检索结果-南通市图书馆

HIV screening and retention in care in people who use drugs in Madrid, Spain: a prospective study

Infectious Diseases of Poverty 2021年第4期10卷 77-85页

作者： Pablo Ryan Jorge Valencia guillermo cuevas Jesus Troya Juan Torres-Macho Maria Jose Munoz-Gomez Nuria Munoz-Rivas Isabel Canorea Sonia Vazquez-Moron Salvador Resino Hospital Universitario Infanta Leonor MadridSpain Universidad Complute nse de Madrid(UCM) MadridSpain Instituto de Investigacion Sanitaria Gregorio Maranon(liSGM) MadridSpain Unidad de Reduccion de Darios"SMASD"Madrid Spain Unidad de Infeccion Viral e Inmunidad Centro Nacional de MicrobiologiaInstituto de Salud Carlos IIICarretera Majada-honda-PozueloKm 2.228220 MajadahondaMadridSpain

Background::The burden of human immunodeficiency virus(HIV)infection in people who use drugs(PWUD)is *** aimed to screen HIV infection among PWUD and describe their retention in HIV ***,we also screen for hepatitis C virus(HCV)infection among HIV-seropositive PWUD and describe their linkage to ***::We conducted a prospective study in 529 PWUD who visited the"Ca?ada Real Galiana"(Madrid,Spain).The study period was from June 1,2017,to May 31,*** diagnosis was performed with a rapid antibody screening test at the point-of-care(POC)and HCV diagnosis with immunoassay and PCR tests on dried blood spot(DBS)in a central *** PWUD were referred to the *** used the Chi-square or Fisher’s exact tests,as appropriate,to compare rates between ***::Thirty-five(6.6%)participants were positive HIV antibodies,but 34 reported previous HIV diagnoses,and 27(76%)had prior antiretroviral *** patients with a positive HIV antibody test,we also found a higher prevalence of homeless(P<0.001)and injection drug use(PWID)(P<0.001),and more decades of drug use(P=0.002).All participants received HIV test results at the *** the 35 HIV positives,28(80%)were retained in HIV medical care at the end of the HIV screening study(2018),and only 22(62.9%)at the end of ***,12/35(34.3%)were positive for the HCV RNA *** the latter,10/12(83.3%)were contacted to deliver the HCV results test(delivery time of 19 days),5/12(41.7%)had an appointment and were attended at the hospital and started HCV therapy,and only 4/12(33.3%)cleared ***::We found almost no new HIV-infected PWUD,but their cascade of HIV care was low and remains a challenge in this population at *** high frequency of active hepatitis C in HIV-infected PWUD reflects the need for HCV screening and reinforcing the link to care.

关键词： HIV Point-of-care Screening People who use drugs Retention in care Hepatitis C Dried blood spot Antiviral treatment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dobesilate for dry age-related macular degeneration

引用

Journal of Biomedical Science and Engineering 2013年第10期6卷 8-14页

作者： Pedro cuevas Luis A.Outeirino Carlos Azanza Javier Angulo guillermo Giménez-Gallego Departamento de Investigación IRYCISHospital Universitario Ramón y CajalMadridSpain Departamento de Oftalmología Hospital de Día Pío XIIMadridSpain Departamento de Estructura y Función de Proteínas Centro de Investigaciones BiológicasCSICMadridSpain

We have evaluated the effects of intravitreal dobesilate, a synthetic fibroblast growth factor inhibitor, in patients with dry age-related macular degeneration, an inflammatory-related retinal disease without available treatment up to date. 36 eyes from 36 patients with dry age-related macular degeneration were treated with a single intravitreal dobesilate injection. The end points were the improvement from baseline visual acuity and normalization of retinal histology at one month. Intravitreal dobesilate injection resulted in a significant improvement in functional and anatomical outcomes at one month after injection. Our results suggest that intravitreal dobesilate may increase the chance of visual acuity gain in dry age-related macular degeneration, even in cases with initial low vision. This study supports the findings of previously published case reports, regarding the short-term improvement in visual acuity by intravitreal dobesilate injection in different degenerative retinal diseases.

关键词： Dry Age-Related Macular Degeneration Fibroblast Growth Factor Inhibition Intravitreal Dobesilate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Dramatic resolution of vitreous hemorrhage after an intravitreal injection of dobesilate

引用

Military Medical Research 2015年第3期3卷 163-165页

作者： Pedro cuevas Luis Antonio Outeirino Carlos Azanza Javier Angulo guillermo Giménez-Gallego Facultad de Medicina Universidad Alfonso X Departamento de Oftalmología Hospital de Día Pío XII Servicio de Histología Departamento de Investigación IRYCISHospital Universitario Ramón y Cajal Departamento de Estructura y Función de Proteínas Centro de Investigaciones Biológicas CSIC

Vitreous hemorrhages are important clinical manifestations of proliferative diabetic retinopathy. Non-cleared vitreous hemorrhages could lead to hemosiderosis bulbi and glaucoma. Here, we describe the case of a type 2 diabetic patient presenting anterior segment and vitreous hemorrhages that resolved three days after treatment with a single intravitreal injection of dobesilate.

关键词： Proliferative diabetic retinopathy Vitreous hemorrhage Dobesilate

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Improvement in the signs and symptoms of dry eye disease with dobesilate eye drops

引用

Journal of Medical Colleges of PLA(China) 2016年第1期31卷 51-55页

作者： Pedro cuevas Luis Antonio Outeiriño Carlos Azanza Javier Angulo guillermo Giménez-Gallego Facultad de Medicina Universidad Alfonso Ⅹ Madrid Spain Departamento de Oftalmología Hospital de Día Pío Ⅻ Madrid Spain Servicio de Histología.Departamento de Investigación IRYCIS Hospital Universitario Ramón y Cajal Madrid Spain Departamento de Estructura y Función de Proteínas Centro de Investigaciones Biológicas.CSIC Madrid Spain

Background:Dry eye is a multifactor disease of the tear film and ocular surface that substantially affects quality of *** presentation:Dobesilate administered as eye drops was well tolerated and effective in treating both the objective signs and subjective symptoms of dry eye disease in this 2-week ***:To the best of our knowledge,this is the first clinical report of using dobesilate in eye *** may provide a novel approach to treating drying diseases of the eye.

关键词： Dry eye disease Dobesilate eye drops Fibroblast growth factor Vascular endothelial growth factor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：