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Robust H∞ Output-feedback Vehicle Yaw Control Using an Active Front Wheel Steering

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Robust H∞ Output-feedback Vehicle Yaw Control Using an Acti...

Differentiation of adipose-derived stem cells toward nucleus pulposuslike cells induced by hypoxia and a three-dimensional chitosan-alginate gel scaffold in vitro

第37届中国控制会议

作者： Jinhao Liang Guodong Yin guangmin Li School of Mechanical Engineering Southeast University

In this paper, we investigate the vehicle stability control problem under the side wind disturbance. To improve the vehicle lateral stability, an active front wheel steering（AFS） is designed based on the robust H∞ output-feedback control. The robust controller takes the wind disturbance and uncertain parameters of the cornering stiffness into consideration while system modeling and controller designing. The simulation with obstacles suddenly encountering shows the vehicle can avoid the obstacles safely and effectively with side wind disturbances. By this way, the controller can improve the vehicle lateral stability and drivability significantly, and reduce the workload of the driver. In addition, good robustness is achieved while uncertain parameters exist.

关键词： Active Front Wheel Steering Robust H∞ output-feedback control Lateral Stabilization Control

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Chinese Medical Journal 2014年第2期127卷 314-321页

作者： Zhang Zhicheng Li Fang Tian Haiquan Guan Kai Zhao guangmin Shan Jianlin Ren Dajiang People's Liberation Army Institute of Orthopedics Beijing Army General Hospital Beijing 100700 China

Background Injectable three-dimensional （3D） scaffolds have the advantages of fluidity and moldability to fill irregularshaped defects,simple incorporation of bioactive factors,and limited surgical ***-derived stem cells （ADSCs） are multipotent and can be differentiated toward nucleus pulposus （NP）-Iike cells.A hypoxic environment may be important for differentiation to NP-like cells because the intervertebral disc is an avascular ***,we investigated the induction effects of hypoxia and an injectable 3D chitosan-alginate （C/A） gel scaffold on *** The C/A gel scaffold consisted of medical-grade chitosan and *** porosity was calculated by liquid displacement *** microstructure was analyzed by light and scanning electron *** were isolated and cultured by conventional *** 2 BrdU-labeled ADSCs were co-cultured with the C/A *** were divided into three groups （control,normoxia-induced,and hypoxia-induced groups）.In the control group,cells were cultured in 10％ FBS/***-induced and normoxia-induced groups were induced by adding transforming growth factor-β1,dexamethasone,vitamin C,sodium pyruvate,proline,bone morphogenetic protein-7,and 1％ ITS-plus to the culture medium and maintaining in 2％ and 20％ O2,*** and morphological changes were observed by light and electron *** were characterized by flow *** viability was investigated by BrdU *** and type Ⅱ collagen were measured by safranin O staining and the Sicool method,*** expression of hypoxia-inducing factor-1α （HIF-1α）,aggrecan,and Type Ⅱ collagen was determined by reverse transcription-polymerase chain *** C/A gels had porous exterior surfaces with 80.57％ porosity and 50-200 μm pore *** cytometric analysis of passage 2 rabbit ADSCs showed high CD90 expression,while CD45 expression was very *** morphology of induced ADSCs resembl

关键词： intervertebral disc degeneration adipose-derived stem cells tissue engineering chitosan-alginate gel

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美联储加息、人民币汇率与价格波动

国际贸易问题 2017年第3期411卷 131-142页

作者：傅广敏浙江省中小企业发展促进中心浙江省经济运行监测中心

随着中国与其它国家的互动关系逐步加强,国内经济更易受外国货币政策冲击的影响。本文通过构建两国经济DSGE模型,采用参数校准法选取模型参数,利用经济变量波动特征和脉冲响应函数,分析了美国加息对人民币汇率和相关价格的影响。研究结... 详细信息

随着中国与其它国家的互动关系逐步加强,国内经济更易受外国货币政策冲击的影响。本文通过构建两国经济DSGE模型,采用参数校准法选取模型参数,利用经济变量波动特征和脉冲响应函数,分析了美国加息对人民币汇率和相关价格的影响。研究结果表明:美国加息会导致中国通货膨胀率下降和股票价格下跌,人民币汇率贬值,但汇率贬值不一定引起出口增加;美国加息冲击发生后,中国股票价格的相对波动性最大,其次是人民币汇率,随后是通货膨胀率,利率的相对波动性最小。最后提出完善宏观调控政策和加强金融宏观审慎管理制度建设等建议。

关键词：美国加息政策外溢人民币汇率两国经济DSGE模型

降钙素联合骨化三醇胶丸对糖尿病合并骨质疏松症的影响

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中国骨质疏松杂志 2019年第1期25卷 103-106页

作者：卢广民周生艳徐剡临沂市经济技术开发区人民医院山东临沂276023 山东兰陵县人民医院山东兰陵276024 内蒙古医科大学附属医院内蒙古呼和浩特010070

目的探讨降钙素联合骨化三醇胶丸治疗糖尿病合并骨质疏松症患者对骨代谢、骨密度及血糖的影响。方法采用配对比较法将我院2011年1月至2015年12月收治的2型糖尿病合并骨质疏松症患者分为接受骨化三醇胶丸治疗的对照组及接受降钙素联合骨... 详细信息

目的探讨降钙素联合骨化三醇胶丸治疗糖尿病合并骨质疏松症患者对骨代谢、骨密度及血糖的影响。方法采用配对比较法将我院2011年1月至2015年12月收治的2型糖尿病合并骨质疏松症患者分为接受骨化三醇胶丸治疗的对照组及接受降钙素联合骨化三醇胶丸治疗的观察组,各40例。两组均接受基础降糖治疗,观察两组患者治疗前及治疗1年后骨代谢、血糖、骨密度情况和治疗期间的不良反应。骨代谢指标包括骨钙素(bone gamma-carboxyglutamic-acid-containing proteins,BGP)、β-胶原片段(beta-crosslaps,β-CTX)、25羟基维生素D[25-hydroxyvitamin D,25(OH)D]、人骨碱性磷酸酶(bone alkaline phosphatase,BALP)、甲状旁腺素(parathyroid hormone,PTH)。结果两组治疗前骨代谢指标、血糖指标及不同部位骨密度对比,差异无统计学意义(P>0.05),观察组治疗1年后BGP、β-CTX、BALP、PTH低于同组治疗前及对照组同期(P0.05);观察组总有效率(97.50%)高于对照组(80.00%)(P0.05)。结论降钙素联合骨化三醇对糖尿病合并骨质疏松患者疗效显著,可有效改善骨代谢,治疗骨质疏松。

关键词：降钙素骨化三醇糖尿病骨质疏松骨代谢骨密度血糖

高寒小嵩草草甸可能成为青藏高原相同地理和气候单元下多种类型草地的偏途演替状态

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Journal of Plant Ecology 2023年第5期16卷 58-72页

作者： Li Lin guangmin Cao Xingliang Xu Fawei Zhang Junjie Huang Bo Fan Bencuo Li Yikang Li Qinghai Haibei National Field Research Station of Alpine Grassland Ecosystem and Key Laboratory of Adaptation and Evolution of Plateau Biota Northwest Institute of Plateau BiologyChinese Academy of SciencesXining 810008China University of Chinese Academy of Sciences Beijing 100049China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 130028China School of Mechanical and Power Engineering Henan Polytechnic UniversityJiaozuo 454000China

高寒嵩草(Kobresia)草甸是青藏高原冬春放牧草场的主体,在放牧强度分异的条件下可以形成特征迥异的稳态。然而,目前还不清楚在不同放牧强度下其他类型草地是否可以演替成为这些稳态。本研究通过土壤剖面特征推断其历史植物群落特征,以... 详细信息

高寒嵩草(Kobresia)草甸是青藏高原冬春放牧草场的主体,在放牧强度分异的条件下可以形成特征迥异的稳态。然而,目前还不清楚在不同放牧强度下其他类型草地是否可以演替成为这些稳态。本研究通过土壤剖面特征推断其历史植物群落特征,以植物群落现场调查确定其现实植物群落特征,以非结构式问卷调查确定草地放牧强度,采用多元回归树模型分析导致草地稳态转化的节点。研究结果表明,高寒灌丛草甸和旱化沼泽草甸在过度放牧条件下均可转化成为高寒矮嵩草(***)草甸和高寒小嵩草(***)草甸,从而使高寒灌丛草甸和旱化沼泽化草甸进入高寒矮嵩草草甸退化演替序列,最终转化成为黑土滩-杂类草次生裸地。以放牧强度为分节点,最多可以将这些植物群落划分为4类稳态,各稳态转化的节点依次为11.0、8.0、5.5羊/ha。所有研究草地总体表现为随放牧强度的增高地上总生物量呈下降趋势。其中,11.0羊/ha是草地转化成为黑土滩杂类草次生裸地的节点。放牧强度改变可以影响植物群落特征及其演替方向,进而改变草地的畜牧生产服务能力,因此放牧强度可以作为反映牧场畜牧生产服务能力的表观指标。未来牧场的可持续发展策略应以草畜平衡为主,合理控制放牧强度,增加草地生产附加值和延伸畜牧业产业链以实现区域草场生态和生产效益的双赢。

关键词：植物群落演替土壤剖面特征区域可持续发展生态系统稳定性状态转化

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CaCO_3软垢的成因

同济大学学报（自然科学版） 2007年第5期35卷 626-630页

作者：李杰朱广敏徐敬同济大学物理系上海200092

依据实验观察和理论计算分析,研究了添加化学阻垢剂使水垢软化的物理机理.实验研究表明:方解石晶粒聚集时形成坚实的硬垢,球霰石聚集时形成松软的软垢;根据球霰石聚集形成的垢体结构,首次提出了球霰石间的聚集是软垢形成的主要机制.实... 详细信息

依据实验观察和理论计算分析,研究了添加化学阻垢剂使水垢软化的物理机理.实验研究表明:方解石晶粒聚集时形成坚实的硬垢,球霰石聚集时形成松软的软垢;根据球霰石聚集形成的垢体结构,首次提出了球霰石间的聚集是软垢形成的主要机制.实验观察表明:添加阻垢剂有效地抑制了方解石晶核的生成几率,从而提升了球霰石在析出物中所占的比例,因而促成了水垢的软化.分子模拟研究和结构分析揭示,阻垢剂只能有效地抑制具有层状生长机制的晶面,即F平面的生长,而不能有效地抑止K晶面的生长,这为阻垢剂促成球霰石生成几率提高提供了理论根据.

关键词：软垢球霰石方解石聚集周期性键链理羟基乙叉二膦酸论

Anacardic acid(6-pentadecylsalicylic acid) induces apoptosis of prostate cancer cells through inhibition of androgen receptor and activation of p53 signaling

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Chinese Journal of Cancer Research 2012年第4期24卷 275-283页

作者： Jing Tan Binghai Chen Leye He Yuxin Tang Zhiqiang Jiang guangmin Yin Jinrong Wang Xianzhen Jiang Department of Urology the third Xiangya Hospital of Xiangya Medical CollegeCentral South University

Anacardic acid （AA） is a mixture of 2-hydroxy-6-alkylbenzoic acid homologs. It is widely regarded as a non-specific histone acetyltransferase inhibitor of p300. The effects and the mechanisms of AA in LNCaP cells （prostate cancer cells） remain unknown. To investigate the effect of AA on LNCaP cells, we had carried out several experiments and found that AA inhibits LNCaP cell proliferation, induces G1/S cell cycle arrest and apoptosis of LNCaP cell. The mechanisms via which AA acts on LNCaP cells may be due to the following aspects. First, AA can regulate p300 transcription and protein level except for its mechanisms regulating function of p300 through post-translational modification in LNCaP cells. Second, AA can activate p53 through increasing the phosphorylation of p53 on Serl 5 in LNCaP cells. AA can selectively activate p21 （target genes of p53）. Third, AA can down-regulates androgen receptor （All） through supressing p300. Our study suggests that AA has multiple anti-tumor activities in LNCaP cells and warrants further investigation.

关键词： Prostate cancer anacardic acid apoptosis LNCaP p300 p53

Corrosion Mechanisms of SEN Slagband Materials

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China's Refractories 2013年第2期22卷 6-10页

作者： Harald HARMUTH Nathalie KBL Barbara ROLLINGER guangmin XIA Chair of Ceramics Montanuniversitaet Leoben RHI AG Voestalpine Stahl GmbH

Wear of a zirconia graphite slagband material by mold slag during casting of a TRIP steel grade was investigated on worn specimens with respect to corrosion and erosion. Corrosion dissolution of both the stabilizer oxide and the zirconia is decisive. Oxidation is dominating graphite wear whereas a possible dissolution in the liquid steel was not observed to play an important role here. The ratio of oxide corrosion to graphite oxidation decreases with decreasing vertical distance of the hot face to the steel bath. Unfortunately and contrary to other applications of carbon bonded refractories in steel industry graphite exhibits to be wetted by mold slag in the special case investigated here： it still acts as a refractive component but only partly as an infiltration inhibitor. Infiltration is followed by zirconia corrosion thus reducing erosion resistance, but nevertheless also gas phase transport of slag components may cause exsolution of the stabilizer oxide in un-infiltrated regions.

关键词： zirconia, graphite corrosion mechanism slagband

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白色石墨润滑涂料研制

非金属矿 2000年第6期23卷 21-22页

作者：王光民青岛石墨股份有限公司莱西南墅266613

利用氟化石墨与其他辅助材料 ,通过一定的工艺研制成功了一种乳胶状的白色石墨悬浮液 ,这种高级润滑涂料适用于机械加工业中金属拉拔、加压以及模具脱模等过程中的润滑 ,是国内目前较为理想的润滑涂料。

关键词：氟化石墨白色悬浮液润滑涂料工艺流程表面处理