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A comparative study of pseudo-static slope stability analysis using different design codes

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Water Science and Engineering 2018年第4期11卷 310-317页

作者： xin-guang yang En-di Zhai Yuan Wang Zhong-bo Hu Central Research Institute of Building and Construction Co. Ltd. MCC Group Beijing 100088 China Goldwind Science & Technology Co. Ltd. Beijing 100176 China College of Mechanics and Materials Hohai University Nanjing 210098 China China Three Gorges Corporation Beijing 100038 China

Many researchers have developed new calculation methods to analyze seismic slope stability problems, but the conventional pseudo-static method is still widely used in engineering design due to its simplicity. Based on the Technical Code for Building Slope Engineering（GB 50330-2013） of China and the Guidelines for Evaluating and Mitigating Seismic Hazards in California（SP117）, a comparative study on the pseudo-static method was performed. The results indicate that the largest difference between these two design codes lies in determination of the seismic equivalence reduction factor( f;). The GB 50330-2013 code specifies a single value for f;of 0.25. In SP117, numerous factors,such as magnitude and distance, are considered in determining f;. Two case studies show that the types of slope stability status evaluated by SP117 are in agreement with those evaluated by the seismic time-history stability analysis and Newmark displacement analysis. The factors of safety evaluated by SP117 can be used in practice for safe design. However, the factors of safety evaluated by GB 50330-2013 are risky for slope seismic design.

关键词： Earthquake Slope stability Pseudo-static method Design code

A pilot study of intraocular lens explantation in 69 eyes in Chinese patients

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International Journal of Ophthalmology(English edition) 2017年第4期10卷 579-585页

作者： Fang Chai Bo Ma xin-guang yang Juan Li Mei-Fang Chu Xi’an No.4 Hospital Shaanxi Ophthalmic Medical CenterAffiliated Guangren HospitalSchool of MedicineXi'an Jiaotong University

AIM：To study the effects of intraocular lens（IOL） explantation and demographic ***：Retrospective non-comparative case *** data recorded from patient charts included the following：demographic,preoperative and postoperative characteristics;complications;surgical methods,and changes in visual ***：A total of 69 eyes in 67 Chinese patients who received IOL explants were *** patients＇ mean age at the time of explantation was 46.1 years old [SD 22.5（6-85）],and 37 patients were female（55.2%）.Regarding employment,47.8% were farmers,23.9% were retired,16.4% were students,4.5% were unemployed,3% were workers,and 4.5% were other（including staff members,teachers and officers）.The main reasons for explantation were dislocation/decentration in 41 cases（59.4%） and retinal detachment in 10 cases（14.5%）.The third most prevalent cause was incorrect lens power in 7 eyes（10.1%）.The remaining reasons were endophthalmitis in 6 cases（8.7%）,posterior capsular opacity in 3 eyes（4.3%）,and impacting retinal surgery operation in 2 cases（2.9%）.The main comorbidities were high myopia in 18 eyes（26.1%）,trauma in 8 eyes（11.6%）,retinal detachment in 6 eyes（8.7%）,congenital cataracts in 8 eyes（11.6%）,and Marfan＇s syndrome in 2 eyes（2.9%）.The mean time from implantation to explantation was 4.0y [SD 4.2（0.005-15）].Treatment after explantation included posterior chamber IOL implantation in 44 eyes（63.8%） and aphakia in 25 eyes（36.2%）.After surgery,the best corrected visual ability（BCVA） was improved in 50 cases（72.5%）,including 28 patients（40.6%） in whom visual ability was improved by more than two ***：Dislocation/decentration is the main cause for explantation,and high myopia is a main risk *** chamber IOL implantation remains the most elected treatment after explantation.

关键词： explantation intraocular lens dislocation

Diagnostic ability of ganglion cell complex thickness to detect glaucoma in high myopia eyes by Fourier domain optical coherence tomography

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International Journal of Ophthalmology(English edition) 2018年第5期11卷 791-796页

作者： Wei-Wei Wang Huai-Zhou Wang Jian-Rong Liu Xi-Fang Zhang Meng Li Yan-Jiao Huo xin-guang yang Department of Ophthalmology Xi'an No.4 HospitalShaanxi Ophthalmic Medical CenterAffiliated Guangren Hospital School of MedicineXi'an Jiaotong University Department of Ophthalmology Beijing Tongren HospitalCapital Medical University

AIM：To evaluate the ability of macular ganglion cell complex（GCC） thickness using Fourier domain optical coherence tomography（FD-OCT） to detect glaucoma in highly myopic ***：Cross-sectional study.A total of 114 participants,consecutively were *** GCC thickness and peripapillary retinal nerve fiber layer（RNFL） thickness were obtained with RTVue *** operating characteristics curves were constructed for each measurement parameter,and areas under the curves（AUCs） were ***：Both the average GCC and average RNFL thickness showed negative correlations with axial length（rGCC=-0.404,P=0.001;rRNFL=-0.561,P〈0.001）.The largest AUCs from GCC,and RNFL parameters were 0.968 [global loss volume（GLV）],and 0.855（average RNFL）,*** was significantly better for detecting high myopic glaucoma than average RNFL（P〈0.001）.CONCLUSION：Macular GCC thickness has higher diagnostic power than peripapillary RNFL thickness to discriminate glaucoma patients from non-glaucoma subjects in high myopia.

关键词： optical coherence tomography glaucoma high myopia ganglion cell complex

Multiphysics simulation and optimization of the in-situ beneficiation process of ilmenite minerals from lunar regolith

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Science China Earth Sciences 2025年第1期68卷 195-207页

作者： Peng ZHANG xin LIU guanghui LIU Wei DAI Hanzhe yang Haibo ZHENG Zhi WANG Ran NIU Yifan BAI yang ZHANG Chengbao LIU Ge yang Junwei yang guang ZHANG Technology and Engineering Center for Space Utilization Chinese Academy of Sciences Beijing Hegong Simulation Co. Ltd

The exploration and utilization of lunar resources have become the major objectives of future lunar exploration missions. The classified collection and processing of lunar minerals is the basic prerequisite for the in-situ exploration and utilization of lunar resources. In this study, we propose a scheme for in-situ separation of magnetic minerals from lunar soils using the dry magnetic separation method. The scheme can realize the purpose of separating magnetic minerals from lunar regolith by altering the motion trajectory of lunar regolith particles with different magnetic properties. Detailed modeling of the dry magnetic separation device is conducted, and the three-dimensional distribution of magnetic parameters is calculated and analyzed. Based on the characterization and analysis of the Chang E-5's samples, the morphologies and physical parameters of lunar regolith particles are modeled and simulated. A discrete element simulation of the motion process of lunar regolith particles under multi-physical field conditions is performed, and the influences of key parameters on the beneficiation performance of lunar magnetic minerals are investigated. Our results indicate that optimal separation and beneficiation of lunar regolith particles can be achieved under specific conditions of magnetic field strength and drum speed. Additionally, we analyze the effects of lunar weak gravity conditions and the charged nature of lunar particles on the beneficiation process, showing that these factors can obviously enhance the beneficiation process of lunar ilmenites. This study demonstrates the feasibility of using the dry magnetic separation method for the beneficiation of magnetic minerals from lunar regolith, providing a theoretical basis for the scientific tasks of collecting, processing, and utilizing lunar mineral resources.

关键词： Lunar regolith In-situ resource utilization Magnetic separation Classified sampling

Late Paleozoic to early Mesozoic volcanic-sedimentary history of the southeastern margin of the Central Asian Orogenic Belt: Timing of uplift of the Inner Mongolia paleo-uplift

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Science China Earth Sciences 2025年第1期68卷 297-309页

作者： Wenxing HAO Jin-Hui yang guang ZHU State Key Laboratory of Lithospheric Evolution Institute of Geology and Geophysics Chinese Academy of Sciences School of Resource and Environmental Engineering Hefei University of Technology

The Kulun region is located in the eastern Bainaimiao arc belt on the southeastern margin of the Central Asian Orogenic Belt(CAOB), adjacent to the North China Craton(NCC) to the south. This region records the closure of the PaleoAsian Ocean during the Paleozoic to early Mesozoic and is key to study the tectonic evolution of the northern margin of the *** conducted zircon U-Pb geochronology and Hf isotope analysis of volcanic-sedimentary and intrusive rocks in the Kulun region. The volcanic-sedimentary rocks were previously assigned an early Carboniferous age, but include volcanic rocks with ages of 267–266 Ma and sedimentary rocks with youngest detrital zircon age peaks of 265–244 Ma, which were intruded by a granite with an age of 242 Ma. This indicates that these rocks are actually middle Permian to Middle Triassic in age(267–242Ma) and correspond to the Qingfengshan and Liujiagou formations. Moreover, two volcanic rock samples have high εHf(t) values(+1.6 to +16.1) and relatively young two-stage Hf model ages(1095–327 Ma), indicating their sources associated with the CAOB. The age spectra and Hf isotopic characteristics of detrital zircons from the sedimentary rocks suggest that, during the middle Permian to Middle Triassic, the sedimentary provenance in the Kulun region was mainly the CAOB. However, by the Early Jurassic, the provenance changed to the NCC(i.e., the Inner Mongolia Paleo-uplift, IMPU). This result, combined with the development of a series of conglomerates on the northern margin of the NCC in the Late Triassic(i.e., xingshikou, Xiaoyingzi,and Xiaohekou formations), indicates the Kulun region experienced an abrupt change in paleogeography during the Late Triassic, with the IMPU undergoing significant uplift and thus becoming the main sediment source in the Kulun region. Based on the Late Triassic alkaline igneous belt(235–215 Ma) in the IMPU, we speculate that this uplift was caused by detachment of the southward-subducting Paleo-Asian oceanic

关键词： Central Asian Orogenic Belt the North China Craton Zircon geochronology Hf isotopes Inner Mongolia Paleo-uplift

Hybrid surgery for symptomatic chronic near-total or total occlusion of the internal carotid artery

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Chinese Medical Journal 2021年第9期134卷 1104-1106页

作者： Chang-Ming Wang Jin-Tao Han Zi-Chang Jia guang-xin yang Xuan Li Department of Vascular Surgery and Interventional Radiology Peking University Third HospitalBeijing 100191China

Stroke is the second leading cause of death globally and accounts for an estimated 5.5 million deaths each year worldwide.[1]Revascularization of the carotid artery is one of the key procedures to reduce the incidence of *** total occlusion(TO)and near-total occlusion(NO)of the carotid artery are *** for TO and NO is controversial with potential complications,including periprocedural stroke,intracranial hemorrhage,and carotid-cavernous fistula(CCF).[2]There have been attempts to implement carotid artery endarterectomy(CEA)and endovascular treatment,but the success rates were far from *** patients with TO,the success rate of revascularization is around 40%and 60%,respectively,for CEA and endovascular technique.[3]For patients with NO,the morbidity and mortality rates are 3%and 9%,respectively.

关键词： carotid occlusion artery

Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： xin yang Yu-Wen Alvin Huang John Marshall Department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

Distribution and mapping of temperate savanna in the sandy lands of eastern China

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Science China Earth Sciences 2025年第1期68卷 128-141页

作者： Xiaoya LI Feng WANG Tao DUAN Kaijie yang Bin yang Chunmei WANG xin TIAN Qi LU Institute of Ecological Conservation and Restoration Institute of Desertification Studies Chinese Academy of Forestry Institute of Desertification Institute of Desertification Studies Chinese Academy of Forestry Institute of Great Green Wall Satellite Application Centre for Ecology and Environment MEE Institute of Microelectronics Chinese Academy of Sciences Aerospace Information Research Institute Chinese Academy of Sciences Institute of Forest Resource Information Techniques Chinese Academy of Forestry

Savannas are distributed globally across various *** perform a significant socioeconomic role in regulating net primary productivity and the terrestrial carbon *** to the high spatial heterogeneity induced by the mixed distribution of trees and grasses,current global land-cover classification maps often classify savannas as forests or grasslands Temperate savannas in China cover a vast area,yet their spatial patterns and extent remain poorly *** study developed a novel remote sensing temperate savannas mapping method by integrating very high-resolution （VHR） unmanned aerial vehicle （UAV） and GF-6 satellite imagery based on the vegetation structure characteristics of temperate savannas using the FAO definition of *** and validation datasets were collected from VHR UAV imagery covering the main temperate savannah types with a ground area of 1818 *** fractional woody vegetation cover （FWVC） and fractional herbaceous vegetation cover （FHVC） in temperate savannas were estimated by integrating Classification and Regression Tree and Random Forest *** current distribution of temperate savannas in the Horqin and Otindag Sandy Lands of Eastern China was mapped to a unit area of 0.5 *** root-mean-square error （RMSE） values for the FWVC and FHVC models were 10.69% and 11.67%,and the R2values were 0.66 and 0.63,*** assessment indicated that the new temperate savanna map had high identification accuracy,with a Kappa coefficient of 0.70,overall accuracy of 0.88,and average accuracy of *** savannas in the sandy lands of eastern China were primarily distributed in the northern Horqin Sandy Land the central and eastern regions of the Otindag Sandy Land,and the transition zone from the southern slopes of the Greater Khingan Mountains to the plains,covering a total area of 3.27×10～6 *** main savannah types were elm,oak/maple,and shrub *** savannas were widely distributed in the Otindag Sandy

关键词： Temperate savanna UAV imagery GF-6 Fractional woody vegetation cover Fractional herbaceous vegetation cover Machine learning

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Multiclass screening of ＞ 200 pharmaceutical and other residues in aquatic foods by ultrahigh performance liquid chromatography-quadrupole-Orbitrap mass spectrometer

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Multiclass screening of ＞ 200 pharmaceutical and other resi...