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Parallel difference schemes with interface extrapolation terms for quasi-linear parabolic systems

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Science China Mathematics 2007年第2期50卷 253-275页

作者： guang-wei yuan xu-deng hang Zhi-qiang SHENG Laboratory of Computational Physics Institute of Applied Physics and Computational MathematicsBeijing 100088China

In this paper some new parallel difference schemes with interface extrapolation terms for a quasi-linear parabolic system of equations are constructed. Two types of time extrapolations are proposed to give the interface values on the interface of sub-domains or the values adjacent to the interface points, so that the unconditional stable parallel schemes with the second accuracy are formed. Without assuming heuristically that the original boundary value problem has the unique smooth vector solution, the existence and uniqueness of the discrete vector solutions of the parallel difference schemes constructed are proved. Moreover the unconditional stability of the parallel difference schemes is justified in the sense of the continuous dependence of the discrete vector solution of the schemes on the discrete known data of the original problems in the discrete W2(2,1) (Q△) norms. Finally the convergence of the discrete vector solutions of the parallel difference schemes with interface extrapolation terms to the unique generalized solution of the original quasi-linear parabolic problem is proved. Numerical results are presented to show the good performance of the parallel schemes, including the unconditional stability, the second accuracy and the high parallelism.

关键词： parallel difference scheme interface extrapolation quasi-linear parabolic system unconditional stability convergence 65M06 65M12 65M55

Inhibition of the cGAS–STING pathway:contributing to the treatment of cerebral ischemia-reperfusion injury

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Neural Regeneration Research 2025年第7期20卷 1900-1918页

作者： hang Yang Yulei Xia Yue Ma Mingtong Gao Shuai Hou Shanshan xu Yanqiang Wang School of Clinical Medicine Shandong Second Medical UniversityWeifangShandong ProvinceChina Department of Emergency The Affiliated Hospital of Weifang Medical UniversityWeifangShandong ProvinceChina Department of Neurology Ⅱ The Affiliated Hospital of Weifang Medical UniversityWeifangShandong ProvinceChina

The cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart,liver,brain,and kidney,but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically ***,we outline the components of the cGAS–STING pathway and then analyze its role in autophagy,ferroptosis,cellular pyroptosis,disequilibrium of calcium homeostasis,inflammatory responses,disruption of the blood–brain barrier,microglia transformation,and complement system activation following cerebral ischemia-reperfusion *** further analyze the value of cGAS–STING pathway inhibitors in the treatment of cerebral ischemia-reperfusion injury and conclude that the pathway can regulate cerebral ischemia-reperfusion injury through multiple *** of the cGAS–STING pathway may be helpful in the treatment of cerebral ischemia-reperfusion injury.

关键词： calcium homeostasis cellular autophagy cerebral ischemia-reperfusion injury cGAS–STING pathway ferroptosis gut–brain–microbiota axis inflammatory light chain 3 microglial cells Syntaxin-17 protein

Review on the progress of ultra-precision machining technologies

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Frontiers of Mechanical Engineering 2017年第2期12卷 158-180页

作者： Julong yuan Binghai LYU wei hang Qianfa deng Ultra-precision Machining Center Zhejiang University of Technology Hangzhou 310014 China Key Laboratory of E&M Zhejiang University of Technology (Ministry of Education and Zhejiang Province) Hangzhou 310014 China

Ultra-precision machining technologies are the essential methods, to obtain the highest form accuracy and surface quality. As more research findings are published, such technologies now involve complicated systems engineering and been widely used in the production of components in various aerospace, national defense, optics, mechanics, electronics, and other high-tech applications. The conception, applications and history of ultra-precision machining are introduced in this article, and the develop- ments of ultra-precision machining technologies, espe- cially ultra-precision grinding, ultra-precision cutting and polishing are also reviewed. The current state and problems of this field in China are analyzed. Finally, the development trends of this field and the coping strategies employed in China to keep up with the trends are discussed.

关键词： ultra-precision grinding ultra-precision cut-ting ultra-precision polishing research status in China,development tendency

Free Vibration Analysis of Moderately-Thick Laminated Doubly-Curved Shells with the Modified Higher-Order Theory

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Acta Mechanica Solida Sinica 2023年第1期36卷 132-142页

作者： yuan Tao Jie xu xuegang yuan hang Yin School of Mathematics Boda College of Jilin Normal UniversitySiping 136000China Department of Mechanics Northeastern UniversityShenyang 110819China School of Science Dalian Minzu UniversityDalian 116600China

In this work,the free vibration properties ofmoderately-thick laminated doubly-curved shells are *** model of the natural frequency of the simply-supported laminated doubly-curved shell is formulated via the variational *** on the numerical solutions,the influences of the shell type,the aspect ratio,the lamination angle and the layer number on the free vibration are *** obtained results show that,for the symmetrically laminated curved shells with fixed thickness,when the layer number is greater than 4,the increasing number has no impact on the natural frequency;however,the lamination angle plays a key role in the fundamental frequency of the spherical shell,while it has little effect on the hyperbolic paraboloid ***,a higher-order shear deformation theory with modified parameters is developed for the moderately-thick laminated doubly-curved shells in this work,i.e.,the geometrically nonlinear strain–displacement relationships are derived with a stricter series expansion form,which are more suitable for the moderately-thick curved shells.

关键词： Vibration analysis Laminated doubly-curved shell Modified displacement fields Higher-order shear deformation

Squeeze flow of interstitial Herschel-Bulkley fluid between two rigid spheres

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Particuology 2010年第4期8卷 360-364页

作者： Chunhui xu Li yuan Yong xu Wenbin hang College of Science China Agricultural University Beijing 100083 China

Interaction between two spheres with an interstitial fluid is crucial in discrete element modeling for simulating the behaviors of ＇wet＇ particulate materials. The normal viscous force of squeeze flow between two arbitrary rigid spheres with an interstitial HerscheI-Bulkley fluid was studied on the basis of Reynolds＇ lubrication theory, resulting in analytical integral expressions of pressure distribution and the viscous force between the two spheres. According to the variation of shear stress, the fluid was divided into yielding and unyielding regions, followed by a discussion on the thickness of the two regions. The result of this paper could be reduced to either the power-law fluid or the Bingham fluid case.

关键词： Wet granuleDiscrete element method Herschel-Bulldey fluid Viscous force

粒子输运离散纵标方程基于界面修正的并行计算方法

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计算物理 2006年第6期23卷 637-641页

作者：袁光伟杭旭登北京应用物理与计算数学研究所北京100088

为了改造粒子输运方程求解的隐式格式,研究设计适应大型并行计算机的并行计算方法,介绍一类求解粒子输运方程离散纵标方程组的基于界面修正的源迭代并行计算方法.应用空间区域分解,在子区域内界面处首先采用迎风显式差分格式进行预估,... 详细信息

为了改造粒子输运方程求解的隐式格式,研究设计适应大型并行计算机的并行计算方法,介绍一类求解粒子输运方程离散纵标方程组的基于界面修正的源迭代并行计算方法.应用空间区域分解,在子区域内界面处首先采用迎风显式差分格式进行预估,构造子区域的入射边界条件,然后,在各个子区域内部进行源迭代求解隐式离散纵标方程组.在源迭代过程中,在内界面入射边界处采用隐式格式进行界面修正.数值算例表明该并行计算方法在精度、并行度、简单性诸方面均具有良好的性质.

关键词：粒子输运方程并行差分方法迭代法界面修正

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爆炸切割网络传爆中的间隙与角度效应

火工品 2025年第1期 37-43页

作者：周晓鹏姜勇袁航中国船舶集团有限公司第七一三研究所河南郑州450015 河南省水下智能装备重点实验室河南郑州450015

为研究爆炸切割网络中传爆节点处传爆能力的关键影响因素,通过改变切割索对传爆药柱的传爆间隙进行了平板传爆试验,将试验结果结合仿真分析确定了JO-11C传爆药柱的仿真材料参数,并进一步分析了传播角度对传爆能力的影响。研究结果表明:... 详细信息

为研究爆炸切割网络中传爆节点处传爆能力的关键影响因素,通过改变切割索对传爆药柱的传爆间隙进行了平板传爆试验,将试验结果结合仿真分析确定了JO-11C传爆药柱的仿真材料参数,并进一步分析了传播角度对传爆能力的影响。研究结果表明:随着传爆间隙的增加,传爆能力下降,切割索对传爆药柱的最大传爆间隙区间为2.0~2.5 mm;同时,传爆角度的增大能够显著提高传爆能力。本研究为爆炸切割网络的传爆性能研究以及提高武器系统的可靠性提供了参考。

关键词：爆炸切割网络传爆间隙传爆角度传爆药柱仿真分析

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Trace Ir(Ⅲ)complex enhanced electrochemiluminescence of AIE-active Pdots in aqueous media

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Science China Chemistry 2020年第5期63卷 715-721页

作者： hang Gao Nan Zhang Yang Li wei Zhao Yiwu Quan Yixiang Cheng Hong-yuan Chen Jing-Juan xu Key Lab of Mesoscopic Chemistry of MOE and Jiangsu Key Laboratory of Advanced Organic Materials School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China Key Laboratory of High Performance Polymer Material and Technology of Ministry of Education Department of Polymer Science and EngineeringSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China

Trace Ir(Ⅲ)complex enhanced aggregation-induced electrochemiluminescence(AIECL)of poly-tetraphenylethene(p TPE)in aqueous media was investigated for the first *** poly-TPE end-capped by Ir(Ⅲ)complex(Ir@p TPE)and its corresponding model polymer poly-TPE(Ph@pTPE)could be synthesized by Suzuki coupling polymerization reaction of 1,2-bis(4-bromophenyl)-1,2-diphenylethene(M-1)with 1,2-diphenyl-1,2-bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethene(M-2)and the continuous Suzuki coupling end-capped reaction of poly-TPE-pinacol boronate with(pq)2 Ir(pico)Br and bromobenzene,***,the corresponding Ir@p TPE Pdots and Ph@p TPE Pdots encapsulated with poly(styrene-co-maleicanhydride)(PSMA)could be obtained by nanoprecipitation *** with Ph@p TPE Pdots,the Ir@p TPE Pdots with a trace amount of Ir(Ⅲ)complex(1.34‰of Ir(Ⅲ)content,wt)could exhibit 9.9-fold enhancement of the electrochemiluminescence(ECL)signal for visual *** work provided a novel strategy on designing highly efficient ECL materials based on trace Ir(Ⅲ)-end capping AIE-active polymer dots.

关键词： electrochemiluminescence aggregation-induced emission Ir(Ⅲ)complex polymer dots

New insight into Ca^(2+)-permeable channel in plant immunity

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Journal of Integrative Plant Biology 2024年第3期66卷 623-631页

作者： wei Wang hang-yuan Cheng Jian-Min Zhou State Key Laboratory of Plant Genomics Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijing 100049China College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China Hainan Yazhou Bay Seed Laboratory Sanya 572025China

Calcium ions(Ca^(2+)) are crucial intracellular second messengers in eukaryotic cells. Upon pathogen perception, plants generate a transient and rapid increase in cytoplasmic Ca^(2+)levels, which is subsequently decoded by Ca^(2+)sensors and effectors to activate downstream immune responses. The elevation of cytosolic Ca^(2+)is commonly attributed to Ca^(2+)influx mediated by plasma membranelocalized Ca^(2+)–permeable channels. However, the contribution of Ca^(2+)release triggered by intracellular Ca^(2+)-permeable channels in shaping Ca^(2+)signaling associated with plant immunity remains poorly understood. This review discusses recent advances in understanding the mechanism underlying the shaping of Ca^(2+)signatures upon the activation of immune receptors, with particular emphasis on the identification of intracellular immune receptors as non-canonical Ca^(2+)-permeable channels. We also discuss the involvement of Ca^(2+)release from the endoplasmic reticulum in generating Ca^(2+)signaling during plant immunity.

关键词： Ca^(2+)-permeable channels endoplasmic reticulum phosphorylation plant immunity resistosome