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Lake sediment treatment with aluminum,iron,calcium and nitrate additives to reduce phosphorus release

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第9期10卷 1367-1373页

作者： guang-rong liu Chun-song YE Jing-hao HE Qin QIAN Hua JIANG College of Power and MechanicalEngineering Wuhan University Wuhan 430072 China

Treatment of lake sediments with salts is a promising approach for preventing phosphorus release from sediments. Five 35-d treatments of undisturbed sediment cores in the East Lake, Wuhan, China were applied under anoxic conditions： nothing added （control）, Al2（SO4）3 added, FeCl3 added, CaCl2 added, and NaNO3 added. To identify changes in the P binding sites in the sediment caused by the treatments, different P binding forms were extracted from the sediment before and after the treatments. We found that the mean P release rates for anoxic treatments with Al2（SO4）3, FeCl3, CaCl2 and NaNO3 were -0.6, 0.03, 0.6 and 2.6 mg/（m^2·d）, respectively, while the P release rate with no additives was 7.3 mg/（m^2·d）. In suboxic conditions, the concentration of total phosphorus （TP ge 657 mg/kg） in sediment was much lower than that of untreated sediment （TPaverage 688 mg/kg） and treatments with salts （TP（Al2（SO4）3） 793 mg/kg, TP（FeCl3） 781 mg/kg, TP（NaNO3） 802 mg/kg, TP（CaCl2） 747 mg/kg）. We also found that adding CaCl2 prevented P release because of apatite formation and because PCa （Ca bound P） increased at the sediment surface. Addition of Fe^3＋ and NO3^- to the sediment increased the amounts of PFe. Mn （Redox-sensitive P, mostly Fe and Mn compounds）, since iron oxide has the ability to combine P. Addition of Al2（SO4）3 increased the fraction of PAl, Fe （P bound to metal oxides （Al, Fe）） and decreased the P and Fe in the water above the anoxic sediment, showing the greater ability orAl in binding P. The results showed that Al2（SO4）3, FeCl3, CaCl2 and NaNO3 all had an effect in controlling phosphorus release. The effect was related to the forms of phosphorus existing in the sediment before treatment and the forms resulting after adding the four reagents. The combination of Al^3＋ or Fe^3＋ with NO3^- promises to be a reasonable chemical treatment for increasing the P retention capacity of sediments in eutrophic lakes. If chemical treatment is combined with bioremediation, the aim o

关键词： Sediment Internal phosphorus Aluminum Iron Calcium Nitrate P fraction

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SURVEY OF AIRBORNE POLLEN IN HUBEI PROVINCE OF CHINA

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Chinese Medical Sciences Journal 2008年第4期23卷 212-217页

作者： guang-hui liu rong-fei Zhu Wei Zhang Wen-jing Li Zhong-xi Wang Huan Chen Department of Allergy Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030

Objective To study the genera and seasonal distribution of airborne pollen in Hubei province of China, and its relationship with pollinosis. Methods From November 2003 to October 2004, an airborne pollen investigation was performed in 16 chosen areas in 12 cities of Hubei province using gravity sedimentation technique. Meanwhile, univalent skin prick tests of pollens were performed and the invasion season was studied on 2 300 patients with pollinosis. Among them, 352 cases underwent the airway responsiveness measurements, and the correlation between airway responsiveness and results of pollen count was analyzed. Results A total of 61 pollen genera were observed and 257 520 pollens were collected. The peak of airborne pollen distribution occurred in two seasons each year: spring (March and April) and autumn (from August to October). The attack of pollinosis corresponded to the peak of pollen distribution. There was a significantly negative relationship between the provocation dose causing a 20% decrease of forced expiratory volume in one second (FEV1) from baseline and airborne pollen concentration (r = -0.6829, P < 0.05). Conclusion This study provides useful information for airborne pollen epidemiology of Hubei province, and it provides important insights to clinical prevention, diagnosis, and treatment of pollen-related allergic diseases.

关键词： airborne pollen pollinosis airway responsiveness

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Unraveling brain aging through the lens of oral microbiota

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Neural Regeneration Research 2025年第7期20卷 1930-1943页

作者： Qinchao Hu Si Wang Weiqi Zhang Jing Qu guang-Hui liu State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Hospital of Stomatology Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Advanced Innovation Center for Human Brain Protection and National Clinical Research Center for Geriatric Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Aging Translational Medicine Center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijingChina CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijingChina University of Chinese Academy of Sciences BeijingChina Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijingChina Aging Biomarker Consortium BeijingChina State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Beijing Institute for Stem Cell and Regenerative Medicine BeijingChina

The oral cavity is a complex physiological community encompassing a wide range of *** of oral microbiota can lead to various oral infectious diseases,such as periodontitis and tooth decay,and even affect systemic health,including brain aging and neurodegenerative *** studies have highlighted how oral microbes might be involved in brain aging and neurodegeneration,indicating potential avenues for intervention *** this review,we summarize clinical evidence demonstrating a link between oral microbes/oral infectious diseases and brain aging/neurodegenerative diseases,and dissect potential mechanisms by which oral microbes contribute to brain aging and *** also highlight advances in therapeutic development grounded in the realm of oral microbes,with the goal of advancing brain health and promoting healthy aging.

关键词： Alzheimer's disease brain aging multiple sclerosis neurodegeneration neurodegenerative diseases oral microbiota Parkinson's disease periodontitis bacteria Porphyromonas gingivalis

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Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

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Neural Regeneration Research 2025年第10期20卷 2955-2968页

作者： Wei Zhang Yubao Lu Ruoqi Shen Yingjie Wu Chenrui liu Xingxing Fang Liangming Zhang Bin liu Limin rong Department of Spine Surgery The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina National Medical Products Administration(NMPA)Key Laboratory for Quality Research and Evaluation of Cell Products GuangzhouGuangdong ProvinceChina guangdong Provincial Center for Quality Control of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina guangdong Provincial Center for Engineering and Technology Research of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina

Microglia,the resident monocyte of the central nervous system,play a crucial role in the response to spinal cord ***,the precise mechanism remains *** investigate the molecular mechanisms by which microglia regulate the neuroinflammatory response to spinal cord injury,we performed single-cell RNA sequencing dataset analysis,focusing on changes in microglial *** found that the MG1 subpopulation emerged in the acute/subacute phase of spinal cord injury and expressed genes related to cell pyroptosis,sphingomyelin metabolism,and neuroinflammation at high ***,we established a mouse model of contusive injury and performed intrathecal injection of siRNA and molecular inhibitors to validate the role of ceramide synthase 5 in the neuroinflammatory responses and pyroptosis after spinal cord ***,we established a PC12-BV2 cell co-culture system and found that ceramide synthase 5 and pyroptosis-associated proteins were highly expressed to induce the apoptosis of neuron *** ceramide synthase 5 expression in a mouse model of spinal cord injury effectively reduced ***,ceramide synthase 5-induced pyroptosis was dependent on activation of the NLRP3 signaling *** ceramide synthase 5 expression in microglia in vivo reduced neuronal apoptosis and promoted recovery of neurological ***2g7 formed a“bridge”between sphingolipid metabolism and ceramide synthase 5-mediated cell death by inhibiting the NLRP3 signaling ***,these findings suggest that inhibiting ceramide synthase 5 expression in microglia after spinal cord injury effectively suppressed microglial pyroptosis mediated by NLRP3,thereby exerting neuroprotective effects.

关键词： ceramide synthase 5 gasdermin D microglia neuroinflammation NLRP3 nuclear factor kappa B Pla2g7 pyroptosis sphingomyelin metabolism spinal cord injury

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DNA的亮绿共振光散射法测定

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分析测试学报 2002年第6期21卷 35-37页

作者：方光荣李玲刘立明宋功武湖北大学化学与材料科学学院湖北武汉430062

研究了在表面活性剂十六烷基三甲基溴化铵 (CTMAB)的存在下 ,碱性染料亮绿(BG)与小牛胸腺脱氧核糖核酸 (ctDNA)体系结合反应及其共振发光光谱 ;在 pH7.3～7.6范围内 ,亮绿在核酸分子表面进行长距组装后 ,在470nm产生共振光散射 (RLS)增... 详细信息

研究了在表面活性剂十六烷基三甲基溴化铵 (CTMAB)的存在下 ,碱性染料亮绿(BG)与小牛胸腺脱氧核糖核酸 (ctDNA)体系结合反应及其共振发光光谱 ;在 pH7.3～7.6范围内 ,亮绿在核酸分子表面进行长距组装后 ,在470nm产生共振光散射 (RLS)增强峰 ,其发光强度与DNA浓度呈线性关系 ;

关键词： DNA 测定亮绿共振光散射法脱氧核糖核酸长距组装分析表面活性剂

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Direct and rapid detection of serum amino acid and monoamine neurotransmitters to assist the diagnosis of panic disorder

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Science China Chemistry 2025年第01期 377-384页

作者： Shiwen liu Xuerui Wan Meng Zhao Jiaqi Wang Weilan Wu Linlin You Yonggui Yuan Qian Xu rong Gao Key Laboratory of Environmental Medicine Engineering Ministry of Education School of Public Health Southeast University Key Laboratory of Modern Toxicology of Ministry of Education Department of Hygienic Analysis and Detection School of Public HealthNanjing Medical University Department of Psychosomatics and Psychiatry Zhongda Hospital School of Medicine Southeast University

The measurement of amino acid and monoamine neurotransmitters（NTs） in serum plays a central role in the identification and monitoring of clinical panic disorder（PD）. However, the strong polarity and chemical heterogeneity of NTs make direct extraction and rapid detection extremely challenging. Herein, we developed a strategy that integrated solid phase extraction based on magnetic Fe3O4coated with polydopamine（Fe3O4@PDA） and direct analysis of mass spectrometry in real time（DART-MS） for quantification of 10 NTs. We systematically investigated the optimal conditions of this strategy to achieve good accuracy and precision. Compared with existing magnetic solid phase extraction methods for NTs detection in biological samples, this strategy could adsorb more targets while having similar adsorption efficiencies, and the total process time was reduced by an average of 69.42%. We rapidly determined the metabolic abnormality of 6 types of NTs in the serum of PD patients and demonstrated their diagnostic accuracy. In addition, an outstanding feature of PD in which tryptophan was more metabolized by the KYN pathway and the 5-hydroxytryptamine pathway was inhibited could be elucidated by this strategy. Our results highlighted the potential ability of Fe3O4@PDA coupled with DART-MS to assist in the clinical diagnosis of PD.

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F_2~m上基于ONB的椭圆曲线加密软件的设计与实现

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计算机科学 2003年第1期30卷 128-130,101页

作者：张险峰秦志光陈兴容刘锦德电子科技大学计算机学院IBM技术中心成都610054

1 引言目前,椭圆曲线密码体制(Elliptic Curve Cryptography,ECC)被认为能比其他公钥体制提供更好的加密强度、更快的执行速度和更小的密钥长度。ECC的安全性基于椭圆曲线离散对数问题的难解性。在实际应用的ECC中,椭圆曲线采用的是基... 详细信息

1 引言目前,椭圆曲线密码体制(Elliptic Curve Cryptography,ECC)被认为能比其他公钥体制提供更好的加密强度、更快的执行速度和更小的密钥长度。ECC的安全性基于椭圆曲线离散对数问题的难解性。在实际应用的ECC中,椭圆曲线采用的是基于有限域F_p或F_2~m的椭圆曲线群。F_p中的域元素为整数集合{0,1,2,…,p-1},其中p为素数。

关键词： F2^m ONB 椭圆曲线加密软件软件设计椭圆曲线密码体制离散对数

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Separation of salidroside from the fermentation broth of engineered Escherichia coli using macroporous adsorbent resins

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Chinese Journal of Chemical Engineering 2022年第4期35卷 260-267页

作者： Xiaocui Sun Xue liu guang-rong Zhao Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering(Ministry of Education) School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300350China Georgia Tech Shenzhen Institute Tianjin UniversityShenzhen 518071China

Salidroside(8-O-β-D-glucoside of tyrosol),a plant-derived natural product,is used for treatment of hypoxia,fatigue and aging *** availability of salidroside is restricted since it is extracted from3-5 years old Rhodiola roots,which grow very slowly in the cold region of northern hemisphere of *** laboratory has constructed an engineered Escherichia coli and established a fermentation process to produce salidroside from *** this article,nine macroporous resins from polarity to non-polarity,including NKA-9,S-8,AB-8,SP825,D101,LSA-8,LX-12,LX-18 and LX-68 resins,were tested to separate salidroside from fermentation *** static and dynamic experiments,the weakly polar SP825 resin had a better separation efficiency among nine *** adsorption kinetic and isotherm of salidroside on the SP825 resin were determined,and the pseudo-second-order kinetic model and Langmuir model could be fitted *** effects of the pH on adsorption and ethanol concentration on desorption were investigated,and an optimal separation process was *** adsorption for salidroside in the SP825 resin column was conducted with loading 150 ml at pH 7,and desorpted by washing 50 ml of80%ethanol *** the best process conditions,the purity and yield of salidroside in the final product were 91.6%and 74.0%,*** results showed that the macroporous SP825 resin would be feasible and effective to prepare salidroside and has promising application in the downstream process of microbial fermentation.

关键词： Adsorption Desorption Fermentation Macroporous resin Salidroside

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Rational modulation of fluorophosphate cathode by anionic groups to reduce the polarization behavior for fast-charging sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 509-521页

作者： Xinyuan Wang Fan Zhang Xingyu Zhou Qian Wang Changyu liu Yangyang liu Hui Wang Xiaojie liu Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education College of Chemistry & Materials Science Northwest University

Na3V2（PO4）2O2F （VP） is recognized as a promising cathode material for sodium-ion batteries due to its stable structural framework and high specific *** functional theory （DFT） and finite element simulations show that incorporating SO42-into VP decreases its band gap,lowers the migration energy barrier,and ensures a uniform Na+concentration gradient and stress distribution during charge and discharge ***,the average Na+diffusion coefficient of Na3V2（PO4）1.95（SO4）0.05O2F（VPS-1） is roughly double that of VP,leading to enhanced rate capability (80 C,75.5 mAh g-1) and cycling stability (111.0 mAh g-1capacity after 1000 cycles at 10 C current density) for ***-1 exhibits outstanding fast-charging capabilities,achieving an 80%state of charge in just 8.1 *** assembled VPS-1//SbSn/NPC full cell demonstrated stable cycling over 200 cycles at a high 5 C current,maintaining an average coulombic efficiency of 95.35%.

关键词： Anionic group modulation Polarization behavior Fast-charging Sodium-ion battery Fluorophosphate Cathode

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智慧医疗情境下四方主体隐私行为的交互机理及演化趋势研究

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现代情报 2025年第1期45卷 135-149页

作者：朱光吴晗逸刘雯南京信息工程大学风险治理与应急决策研究院江苏南京210044 南京信息工程大学管理工程学院江苏南京210044

[目的/意义]本文针对智慧医疗情境下隐私行为研究在博弈主体、模型参数等方面的不足,探寻患者、医疗机构、智慧医疗平台和政府四方主体之间的隐私行为交互机理与演化趋势。[方法/过程]基于演化博弈理论,构建患者、医疗机构、智慧医疗平... 详细信息

[目的/意义]本文针对智慧医疗情境下隐私行为研究在博弈主体、模型参数等方面的不足,探寻患者、医疗机构、智慧医疗平台和政府四方主体之间的隐私行为交互机理与演化趋势。[方法/过程]基于演化博弈理论,构建患者、医疗机构、智慧医疗平台和政府四方博弈模型。根据不同参数调节下各方行为策略的收益、成本、损失等计算收益矩阵,求解主体的演化稳定策略,并考虑不同因素对主体行为策略及系统稳定状态的影响。[结果/结论]患者的隐私披露行为与披露隐私后获得的服务收益密切相关,医疗机构的隐私保护投入成本和隐私泄露概率对其隐私保护行为有显著影响,智慧医疗平台的政府奖惩、罚款收益和投入成本是影响其严格管理行为的关键因素,政府的监管行为与奖惩机制等因素密切相关。通过应用本文模型和方法,可以动态调整隐私保护机制,明确各方职责,推动智慧医疗可持续健康发展。

关键词：智慧医疗演化博弈隐私行为患者医疗机构智慧医疗平台政府

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