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Biomedical and Environmental Sciences 2022年第4期35卷 351-355页

作者： ZHANG Bo ZHANG Jing YAO Bin Wei xu Xin ping WANG Hui ZHAO Li DONG Ji WANG Hao Yu TAN Sheng Zhi PENG Rui Yun Department of Experimental Pathology Beijing Institute of Radiation MedicineBeijing 100850China Department of Pathology Beiya Orthopedic HospitalBeijing 100102China

With the in creasing use of microwave technology in wireless communication,medical research,and other fields,the risk of energy leakage and excessive human exposure requires more *** to a certain frequency of microwave has been found to have harmful effects on multiple organs,including the heart[1-3],which is an important organ for blood circulation and any injury to which can cause a series of adverse consequences.

关键词： organs microwave consequences

Risk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis:a nationwide retrospective study in China

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World Journal of Pediatrics 2024年第5期20卷 506-516页

作者： Li-Wen Tan Jun-Li Wan Chun-Hua Zhu Hong xu Zheng-Kun Xia Li-Zhi Chen Xiao-Chuan Wu Fang Wang Xiao-Rong Liu Cheng-guang Zhao Xiao-Zhong Li Jian-Hua Mao Xiao-Wen Wang Wen-Yan Huang Yu-Hong Li Jian-Jiang Zhang Shi-Pin Feng Jun Yang Jiao-Jiao Liu Chun-Lin Gao Li-ping Rong Lan-Jun Shuai Ke xu He-Jia Zhang Qiu Li Ai-Hua Zhang Mo Wang Department of Nephrology Children’s Hospital of Chongqing Medical UniversityZhongshan 2nd Rd.136Chongqing400014China Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChildren’s Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of Pediatrics Children’s Hospital of Chongqing Medical UniversityChongqingChina Department of Nephrology Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing210008China Department of Nephrology Children’s Hospital of Fudan UniversityNational Paediatric Medical Center of ChinaShanghaiChina Department of Pediatrics Jinling HospitalNanjing Medical UniversityNanjingChina Department of Pediatrics Jinling HospitalThe First School of Clinical MedicineSouthern Medical UniversityNanjingChina Department of Pediatrics Jinling HospitalMedical School of Nanjing UniversityNanjingChina Department of Pediatric Nephrology and Rheumatology The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhouChina Department of Pediatrics The Second Xiangya Hospital of Central South UniversityChangshaChina Department of Pediatrics Peking University First HospitalBeijingChina Department of Nephrology Beijing Children’s HospitalCapital Medical UniversityBeijing100045China National Center for Children’s Health BeijingChina Department of Pediatrics Shengjing Hospital of China Medical UniversityShenyangChina Department of Nephrology and Immunology Children’s Hospital of Soochow UniversitySuzhouChina Department of Nephrology Children HospitalZhejiang University School of MedicineHangzhouChina Department of Nephrology Wuhan Children’s Hospital(Wuhan Maternal and Child Healthcare Hospital)Tongji Medical CollegeHuazhong University of Science&TechnologyWuhanChina Department of Nephrology and Rheumatology Shanghai Children’s HospitalSchool

Background Pediatric antineutrophil cytoplasmic antibody-associated vasculitis(AAV)is a life-threatening systemic vasculitis featured by liability to renal ***,there are few studies on the risk factors and predictive models for renal outcomes of AAV in *** Data from 179 AAV children in multiple centers between January 2012 and March 2020 were collected *** risk factors and predictive model of end-stage renal disease(ESRD)in AAV were *** Renal involvement was the most typical manifestation(95.5%),and the crescent was the predominant pathological lesion(84.9%).The estimated glomerular filtration rate(eGFR)was evaluated in 114 patients,of whom 59.6%developed ESRD,and the median time to ESRD was 3.20 *** eGFR[P=0.006,odds ratio(OR)=0.955,95%confidence interval(CI)=0.924–0.987]and the percentages of global glomerulosclerosis(pGGS;P=0.018,OR=1.060,95%CI=1.010–1.112)were independent risk factors for ESRD of renal *** on the pGGS and eGFR at renal biopsy,we developed three risk grades of ESRD and one predictive *** Kaplan‒Meier curve indicated that renal outcomes were significantly different in different risk grades(P<0.001).Compared with serum creatinine at baseline,the predictive model had higher accuracy(0.86 versus 0.58,P<0.001)and a lower coefficient of variation(0.07 versus 0.92)in external *** Renal involvement is the most common manifestation of pediatric AAV in China,of which more than half deteriorates into *** predictive model based on eGFR at renal biopsy and the pGGS may be stable and accurate in speculating the risk of ESRD in AAV children.

关键词： Antineutrophil cytoplasmic antibody End-stage renal disease Glomerulonephritis Pediatric nephrology Vasculitis

Plant above-ground biomass and litter quality drive soil microbial metabolic limitations during vegetation restoration of subtropical forests

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Soil Ecology Letters 2023年第2期5卷 103-115页

作者： Shuo Zhang Ying-ping Wang Xi Fang Jinlei Chen Nannan Cao pingping xu Mengxiao Yu Xin Xiong Xiangping Tan Qi Deng Junhua Yan Key Laboratory of Vegetation Restoration and Management of Degraded Ecosystems South China Botanical GardenChinese Academy of SciencesGuangzhou 510650China University of Chinese Academy of Sciences Beijing 100049China CSIRO Oceans and Atmosphere PMB 1AspendaleVictoria 3195Australia Faculty of Life Science and Technology Central South University of Forestry and TechnologyChangsha 410004China

Changes in litter quality(carbon:nitrogen,C:N)and above-ground biomass(AGB)following vegetation restoration significantly impact soil physicochemical properties,yet their effects on soil microbial metabolic limitations remain *** measured litter quality,AGB,soil physicochemical properties,and extracellular enzyme activity(EEA)along a vegetation restoration gradient(7,14,49,70 years,and nearly climax evergreen broadleaved forests)in southern *** also evaluated soil microbial metabolic limitations by a vector analysis of the *** revealed the soil microbial metabolisms were co-limited by C and phosphorus(P).The microbial C limitation initially decreased(before 14 years)and then increased,while the microbial P limitation initially increased(before 49 years)and then *** least squares path modeling(PLS-PM)showed that the microbial C limitation was mainly attributed to microbial C use efficiency induced by litter quality,suggesting that microorganisms may transfer cellular energy between microbial growth and Cacquiring enzyme *** microbial P limitation was primarily correlated with AGB-driven change in soil elements and their stoichiometry,highlighting the importance of nutrient stoichiometry and balance in microbial *** shifts between microbial C and P limitations and the strong connections of plant–soil-microbe processes during vegetation restoration revealed here will provide us with helpful information for optimal management to achieve forest restoration success.

关键词： Extracellular enzymatic stoichiometry Microbial metabolic limitations Above-ground biomass Litter quality Vegetation restoration Subtropic

Generalized Hyers-Ulam Stability of a General Mixed Additive-cubic Functional Equation in Quasi-Banach Spaces

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Acta Mathematica Sinica,English Series 2012年第3期28卷 529-560页

作者： Tian Zhou xu John Michael RASSIAS Wan Xin xu School of Mathematics Beijing Institute of Technology Pedagogical Department E.E. Section of Mathematics and InformaticsNational and Capodistrian University of Athens Department of Electrical and Computer Engineering College of EngineeringUniversity of Kentucky

In this paper, we establish a general solution and the generalized Hyers-Ulam-Rassias stability of the following general mixed additive-cubic functional equation

关键词： Stability additive mapping cubic mapping quasi-Banach space p-Banach space

STRONGLY　ALGEBRAIC　LATTICES　AND　CONDITIONS　OF　MINIMAL　MAPping　PRESERVING　INFS

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Chinese Annals of Mathematics,Series B 1994年第1期15卷 105-114页

作者： xu XIAOQUAN JIANGXI NORMAL UNIV DEPT MATHNANCHANG 330027PEOPLES R CHINA

The tabor gives some characterizations of strongly algebraic lattices, and proves that thecategory of strongly algebraic lattices is complete and cocomplete. Finally, this paper gives thecomplete conditions under whic... 详细信息

关键词： Strongly algebraic lattice Category of strongly algebraic lattices Completeness and cocompleteness Minimal mapping.

Effect of Zinc and Composting Time on Dynamics of Different Soluble Copper in Chicken Manures

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Agricultural Sciences in China 2010年第6期9卷 861-870页

作者： LU Li-lan WANG xu-dong xu Ming-hui College of Resources and Environmental Sciences Northwest A&F University Yangling 712100 P.R.China Hainan Branch Institute of Medical Plant Development Chinese Academy of Medical Sciences Wanning 571533 P.R.China

Chicken manures added with Cu and Zn were used for composting experiment to study the dynamics of different soluble humus complexed copper （H2O-Cu,NaOH-Cu and NaOH-Na4P2O7-Cu）.The effect of zinc in compost on humus complexed copper and the relationship between humus complexed copper were also *** results showed that H2O-Cu increased before the 45 d of composting and decreased *** the treatments of 1：1,2：1 and 3：1 with the added copper content increasing,H2O-Cu increased with decomposition *** high level zinc in manure could decrease the relative H2O-Cu content at the last stage of ***-Cu decreased greatly with the compost *** the added copper content increasing in manure,the percentage of NaOH-Cu to total copper *** zinc had no significant impact on NaOH-Cu ***-Na4P2O7-Cu increased with *** the added copper content increasing in compost manure,the percentage of NaOH-Na4P2O7-Cu to total copper increased,and showed an increase trend with composting *** zinc in manure increased *** composts,55-80% of extracted copper was present in NaOH fraction,10-30% in NaOH-Na4P2O7-Cu fraction,and 0-10% in H2O *** the added copper or zinc contents increased in manures,the distribution percent of NaOH- Na4P2O7-Cu （pressed as percent of extracted Cu） increased and that of H2O-Cu and NaOH-Cu *** extracted Cu （H2O,NaOH and Na4P2O7） were strongly correlated to each other,H2O-Cu and NaOH-Na4P2O7-Cu were significantly correlated to H2O-extracted organic C and NaOH-Na4P2O7-extracted organic C,respectively.

关键词： chicken manure extractable copper extractable organic C

Role of p300 in the pathogenesis of Henoch-Schonlein purpura nephritis and as a new target of glucocorticoid therapy in mice

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Chinese Medical Journal 2019年第16期132卷 1942-1950页

作者： Ming-Yu Jiang Wei Li Xiang-ping xu Jie-Qing Zhou Hong Jiang Department of Pediatrics The First Affiliated Hospital of China Medical UniversityShenyangLiaoning 110001China Department of Pediatrics The First Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150001China

Background: Henoch-Schonlein purpura nephritis (HSPN) is a very common secondary kidney disease of childhood. Its pathogenesis and the treatment mechanism of glucocorticoid have not been fully elucidated. The aim of this study was to determine the relationship between p300 and the pathogenesis, glucocorticoid therapy in mice with HSPN, respectively. Methods: Forty-eight C57BL/6N male mice, weighing 18 to 20 g, were selected (3–4 weeks old, n = 8 per group). The mice in the normal control group (Group I) were given normal solvent and the HSPN model group (Group II) were given sensitizing drugs. The mice in Group III were injected intraperitoneally with dexamethasone after being given sensitizing drugs. Meanwhile, mice in Groups IV, V and VI with conditional knockout of p300 were also given normal solvent, sensitizing drugs and dexamethasone. The levels of serum IgA, creatinine, and circulating immune complex (CIC) concentrations, 24 h urinary protein and urinary erythrocyte in C57 wild mice, and p300 conditional knockout mice in each group were measured. The expression of p300 in renal tissues and the expression of glucocorticoid receptor (GR)α and β, transforming growth factor (TGF)-β1, and activator protein (AP)-1 after dexamethasone treatment were determined by real-time polymerase chain reaction and Western blotting. Results: Compared with the normal solvent control group (Group I), the expression of p300 mRNA in the model group (Group II) was significantly up-regulated. Western blotting further confirmed the result. Urinary erythrocyte count, 24 h urinary protein quantification, serum IgA, CIC, and renal pathologic score in Group V were distinctly decreased compared with non-knockout mice in Group II (9.7 ± 3.8 per high-power field [/HP] vs. 18.7 ± 6.2/HP, t = 1.828, P = 0.043;0.18 ± 0.06 g/24 h vs. 0.36 ± 0.08 g/24 h, t = 1.837, P = 0.042;18.78 ± 0.85 mg/mL vs. 38.46 ± 0.46 mg/mL, t = 1.925, P = 0.038;0.80 ± 0.27 μg/mL vs. 1.64 ± 0.47 μg/mL, t = 1.892, P = 0.04

关键词： p300 Henoch-Schonlein purpura nephritis Pathogenesis Glucocorticoid treatment

Post-subdution evolution of the Northern Lhasa Terrane, Tibet: Constraints from geochemical anomalies, chronology and petrogeochemistry

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China Geology 2022年第1期5卷 84-95页

作者： Shi-mian Yu xu-dong Ma Yan-chun Hu Wei Chen Qing-ping Liu Yang Song Ju-xing Tang Geological Museum of Guizhou Guiyang 550081China MNR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesChinese Academy of Geological SciencesBeijing 100037China No.1 Institute of Geology and Mineral Resources of Shandong Province Jinan 250014China

Bangong-Nujiang collisional zone(BNCZ)is an older one in Qinghai-Tibet Plateau and resulted in the famous Bangong-Nujiang metallogenic belt,which plays an important role in evaluating the formation and uplift mechanism of *** northern and central Lhasa Terrane composed the southern part of the *** ore deposits can be used as markers of geodynamic evolution,the authors carried 1∶50000 stream sedimental geochemical exploration in the Xiongmei area in the Northern Lhasa Terrane to manifest the mineralization,and based on this mineralization with geochemical and chronological characteristics of related magmatic rocks to constrain their geodynamics and connection with the evolution of the Lhasa *** authors find Early Cretaceous magma mainly resulted in Cu,Mo mineralization,Late Cretaceous magma mainly resulted in Cu,Mo,and W mineralization in the studying *** results suggest a southward subduction,slab rolling back and break-off,and thickened lithosphere delamination successively occurred within the Northern Lhasa Terrane.

关键词： Bangong-Nujiang collisional zone Geochemical anomalies Mineralization Slab rolling-back/break-off Delamination Northern Lhasa Terrane Geological survey engineering Tibet

Wear State Recognition of Drills Based on K-means Cluster and Radial Basis Function Neural Network

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International Journal of Automation and computing 2010年第3期7卷 271-276页

作者： xu Yang Department of Mechanical System Engineering Faculty of Engineering Gunma University Kiryu 376-8515 Japan Department of Mechanical Engineering School of Mechanical Engineering and Automation Dalian Polytechnic University Dalian 116034 PRO

Drill wear not only affects the surface smoothness of the hole, but also influences the life of the drill. Drill wear state recognition is important in the manufacturing process, which consists of two steps： first, decomposing cutting torque components from the original signals by wavelet packet decomposition （WPD）; second, extracting wavelet coefficients of different wear states （i.e., slight, normal, or severe wear） with signal features adapting to Welch spectrum. Finally, monitoring and recognition of the feature vectors of cutting torque signal are performed by using the K-means cluster and radial basis function neural network （RBFNN）. The experiments on different tool wears of the multivariable features reveal that the results of monitoring and recognition are significant and effective.

关键词： Drill wear state recognition cutting torque signals wavelet packet decomposition (WPD) Welch spectrum energy K-means cluster radial basis function neural network

Mesoporous MnSiO3@Fe3O4@C Nanoparticle as p H-responsive T1-T2* Dual-modal Magnetic Resonance Imaging Contrast Agent for Tumor Diagnosis

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Chinese Journal of Chemical Physics 2019年第3期32卷 391-398,I0002,I0003-I0012页

作者： Bei-chen Duan Peng-ping xu Zhen Guo Qian-wang Chen Hefei National Laboratory for Physical Sciences at the Microscale Collaborative Innovation Center of Suzhou Nano Science and TechnologyDepartment of Materials Science & EngineeringCAS High Magnetic Field LaboratoryUniversity of Science and Technology of ChinaHefei 230026China Anhui Key Laboratory for Cellular Dynamics and Chemical Biology and School of Life Sciences University of Science and Technology of ChinaHefei 230026China

Mesoporous structured MnSiO3@Fe3O4@C nanoparticles(NPs)were prepared via a facile and efficient strategy,with negligible cytotoxicity and minor side *** as-prepared MnSiO3@Fe3O4@C NPs hold great potential in serving as pH-responsive T1-T2^*dual-modal magnetic resonance(MR)imaging contrast *** released Mn^2+shortened T1 relaxation time,meanwhile the superparamagnetic Fe3O4 enhanced T2 contrast *** release rate of Mn ions reaches 31.66%under the condition of pH=5.0,which is similar to tumor microenvironment and *** assays show that MnSiO3@Fe3O4@C NPs have minor toxicity,even at high *** intravenous injection of MnSiO3@Fe3O4@C NPs,a rapid contrast enhancement in tumors was achieved with a significant enhancement of 132%after 24 h of the ***,a significant decreasement of 53.8%was witnessed in T2 MR imaging *** demonstrated that MnSiO3@Fe3O4@C NPs can act as both positive and negative MR imaging contrast ***,owing to the pH-responsive degradation of mesoporous MnSiO3,MnSiO3@Fe3O4@C NPs can also be used as potential drug systems for cancer theranostics.

关键词： Magnetic resonance imaging MnSiO3@Fe3O4@C Dual-modal Contrast agent