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The Chinese Society of Clinical Oncology(CSCO)clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma

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Cancer Communications 2021年第11期41卷 1195-1227页

作者： Ling-Long Tang Yu-Pei Chen Chuan-Ben Chen Ming-Yuan Chen Nian-Yong Chen Xiao-Zhong Chen Xiao-Jing Du Wen-Feng Fang Mei Feng Jin Gao Fei Han Xia He Chao-Su Hu De-sheng Hu guang-Yuan Hu Hao Jiang Wei Jiang Feng Jin Jin-Yi Lang Jin-Gao Li Shao-jun Lin Xu Liu Qiu-Fang Liu Lin Ma Hai-Qiang Mai Ji-Yong Qin Liang-Fang shen Ying Sun Pei-Guo Wang Ren-sheng Wang Ruo-Zheng Wang Xiao-shen Wang Ying Wang Hui Wu Yun-Fei Xia Shao-Wen Xiao Kun-Yu Yang jun-Lin Yi Xiao-Dong Zhu jun Ma Department of Radiation Oncology State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center of Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapySun Yat-sen University Cancer Center651 Dongfeng Road EastGuangzhouGuangdong 510060P.R.China Department of Radiation Oncology Fujian Provincial Cancer HospitalFujian Medical University Department of Radiation OncologyTeaching Hospital of Fujian Medical University Provincial Clinical CollegeCancer Hospital of Fujian Medical UniversityFuzhouFujian 350014P.R.China Department of Nasopharyngeal Carcinoma State Key Laboratory of Oncology in South ChinaCollaborative Innovation Centre for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapySun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Radiation Oncology Cancer CenterWest China HospitalSichuan UniversityChengduSichuan 610041P.R.China Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital)Institute of Cancer and Basic Medicine(IBMC)Chinese Academy of Sciences HangzhouZhejiang 310000P.R.China State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineMedical Oncology DepartmentSun Yat-Sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Radiation Oncology Sichuan Cancer Hospital and InstituteSichuan Cancer CenterSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan 610041P.R.China Department of Radiation Oncology Anhui Provincial Hospital Affiliated to Anhui Medical UniversityHefeiAnhui 230001P.R.China Department of Clinical Laboratory Affiliated Cancer Hospital of Nanjing Medical UniversityJiangsu Cancer HospitalJiangsu Institute of Cancer ResearchNanjingJiangsu 210000P.R.China Department of Radiation Oncology Fudan University Shanghai Cancer CenterShanghai 200032P.R.China Department of Radiotherapy Hubei Cancer HospitalTong

Nasopharyngeal carcinoma(NPC)is a malignant epithelial tumor originating in the nasopharynx and has a high incidence in Southeast Asia and North *** develop these comprehensive guidelines for the diagnosis and management of NPC,the Chinese Society of Clinical Oncology(CSCO)arranged a multi-disciplinary team comprising of experts from all sub-specialties of NPC to write,discuss,and revise the *** on the findings of evidencebased medicine in China and abroad,domestic experts have iteratively developed these guidelines to provide proper management of ***,the guidelines describe the screening,clinical and pathological diagnosis,staging and risk assessment,therapies,and follow-up of NPC,which aim to improve the management of NPC.

关键词： Chinese Society of Clinical Oncology CSCO Nasopharyngeal carcinoma Diagnosis Staging Risk Radiotherapy Chemotherapy Surgery Immunotherapy

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突发公共卫生事件可防可控吗?

医学争鸣 2014年第4期5卷 57-59,62页

作者：柴光军空军后勤部卫生防疫队北京100076

突发公共卫生事件是人类社会面临的最重要公共卫生问题之一,但对突发公共卫生事件的定义、内涵和性质的认识还存在很多模糊之处,特别是对突发公共卫生事件是否可防可控、如何防控更是有不同的理解。本文在总结近年来相关的研究进展、梳... 详细信息

突发公共卫生事件是人类社会面临的最重要公共卫生问题之一,但对突发公共卫生事件的定义、内涵和性质的认识还存在很多模糊之处,特别是对突发公共卫生事件是否可防可控、如何防控更是有不同的理解。本文在总结近年来相关的研究进展、梳理相应的法律法规、结合防治工作的实践经验的基础上,对这些问题进行了系统阐述。

关键词：突发公共卫生事件预防控制

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煤焦颗粒催化气化过程中分形特性的原位研究

燃料化学学报 2022年第5期50卷 523-529页

作者：陈倩韦兵陈俊潜江航叶奕强王兴军郭庆华于广锁王辅臣华东理工大学资源与环境工程学院上海200237 上海市煤气化工程技术研究中心上海200237

通过高温热台原位研究气化阶段钾基催化剂对神府煤焦的催化气化作用。考察了气化温度(800−900℃)和催化剂负载量(4.4%、10%(质量分数))对煤焦反应性能的影响。通过热台显微镜对煤焦颗粒催化气化过程进行可视化研究并引入分形理论对煤焦... 详细信息

通过高温热台原位研究气化阶段钾基催化剂对神府煤焦的催化气化作用。考察了气化温度(800−900℃)和催化剂负载量(4.4%、10%(质量分数))对煤焦反应性能的影响。通过热台显微镜对煤焦颗粒催化气化过程进行可视化研究并引入分形理论对煤焦颗粒表面结构进行分析,揭示分形维数所表征的气化反应性。实验结果表明,煤焦颗粒的分形维数与之碳转化率呈正相关性,即催化剂负载量一定,改变气化温度,分形维数愈大,煤焦颗粒的碳转化率越大;气化温度一定,改变催化剂负载量,分形维数愈大,煤焦颗粒的碳转化率越大;煤焦颗粒的初始气化反应速率与分形维数关系与碳转化率一致;煤焦颗粒的分形维数与煤焦球度、角度间相关性较大,存在指数关系;即分形维数随煤焦颗粒角度的增加而增大;煤焦颗粒分形维数指标可用于煤焦催化气化过程的研究。

关键词：原位高温热台煤焦颗粒分形特性催化气化气化反应性

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单螺杆挤出超高分子量聚乙烯管材的熔融理论

高分子材料科学与工程 2008年第10期24卷 9-11,16页

作者：秦建华杨光政王光军武汉工程大学机械工程学院湖北武汉430073

利用传热学理论结合UHMWPE单螺杆挤出管材的成型规律,采用数值计算法(有限差分法)建立起基于UHMWPE单螺杆挤出机的熔融数学模型,并开发出相应CAD软件,采用该软件能比较客观准确地对原料的熔融过程进行数值模拟,对正确设计UHMWPE单螺杆... 详细信息

利用传热学理论结合UHMWPE单螺杆挤出管材的成型规律,采用数值计算法(有限差分法)建立起基于UHMWPE单螺杆挤出机的熔融数学模型,并开发出相应CAD软件,采用该软件能比较客观准确地对原料的熔融过程进行数值模拟,对正确设计UHMWPE单螺杆挤出机的结构参数提供了理论基础。

关键词：超高分子量聚乙烯机简成型法熔融理论数值模拟

高压压气机出口级叶型加工偏差影响的相关性分析

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工程热物理学报 2022年第4期43卷 929-938页

作者：于贤君李明志安广丰刘佳鑫刘宝杰北京航空航天大学航空发动机研究院北京100191 北京航空航天大学能源与动力工程学院北京100191 航空发动机气动热力国防重点实验室北京100191

为探索叶型表面不同区域之间偏差的相互耦合影响规律,本文以高压压气机出口级转子叶中截面叶型作为研究对象,采用互相关敏感性分析方法开展相关性研究,旨在为发展几何偏差的快速气动影响评估方法提供必要的理论支持。本文通过Hicks-Henn... 详细信息

为探索叶型表面不同区域之间偏差的相互耦合影响规律,本文以高压压气机出口级转子叶中截面叶型作为研究对象,采用互相关敏感性分析方法开展相关性研究,旨在为发展几何偏差的快速气动影响评估方法提供必要的理论支持。本文通过Hicks-Henne函数对叶型的局部几何偏差进行建模,采用蒙特卡洛模拟以及代理模型方法对偏差叶型的气动性能进行数值计算。通过分析计算结果,得到了叶型表面不同位置局部几何偏差对叶型气动性能非线性影响的相关性规律,进一步优化了考虑加工成本和叶型性能的偏差控制准则。研究结果表明,叶型局部几何偏差敏感性受局部几何偏差与偏差点上游边界层的相对尺度大小影响,局部几何偏差导致的边界层尺度变化是影响不同区域之间偏差相关性的主要因素。

关键词：加工偏差敏感性分析蒙特卡洛法压气机性能

秦汉县级诸官的流变:以出土文献为中心的讨论

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社会科学 2023年第1期 54-63页

作者：沈刚吉林大学古籍研究所、“古文字与中华文明传承发展工程”协同攻关创新平台

秦汉县级诸官系统的基本职责是保障行政运转。里耶秦简“迁陵吏志”中10个诸官分别是仓、司空、库、少内、田、田官、畜官、都乡、启陵乡、贰春乡。诸官除了服务官府外,还是以经济活动为主的业务部门。诸官体系在汉代依然存在,但其生产... 详细信息

秦汉县级诸官系统的基本职责是保障行政运转。里耶秦简“迁陵吏志”中10个诸官分别是仓、司空、库、少内、田、田官、畜官、都乡、启陵乡、贰春乡。诸官除了服务官府外,还是以经济活动为主的业务部门。诸官体系在汉代依然存在,但其生产功能弱化,机构和吏员减省,一些服务类职官地位上升。这是因为汉代郡的地位上升,有更大的事权,能够组织起公共生产服务,并拥有一些专门的生产职官,而县廷则相形见绌。此外,客观条件的变化也造成了部分县级诸官的消失。秦代县廷控制刑徒劳动力较多,而汉代多使用小农劳役,这也导致了县级诸官收缩。同时,秦代和汉代史料记载的偏差也在一定程度上塑造着我们今日对秦汉诸官演变的直观印象。

关键词：秦汉简牍诸官列曹

Elevated nocturnal and morning blood pressure in patients with obstructive sleep apnea syndrome

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Chinese Medical Journal 2012年第10期125卷 1740-1746页

作者： HE Quan-ying FENG Jing ZHANG Xilong LIANG Zong-an HUANG Shao-guang KANG Jian WANG guang-fa ZHANG Li-qiang MA Li-jun WANG Bei LIN Qi-chang ZHANG Jin-nong LIU Hui-guo LUO Yuan-ming LIU Jian-hong WANG Shi XIAO Gao-hui LU Gan ZHANG Jin FENG Xue-wei CHEN Bao-yuan Department of Respiratory Diseases Peking University People’s HospitalBelling 100044China Department of Respiratory Diseases Tianjin Medical University General HospitalTianiin 300052China Department of Respiratory Diseases First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China Department of Respiratory Diseases West China HospitalSichuan UniversityChengduSichuan 610041China Department of Respiratory Diseases Ruijin HospitalShanghai Jiao Tbng University School of MedicineShanghai 200025China Department of Respiratory Diseases First Affiliated Hospita1 ofChina Medical UniversityShenyangLiaoning 110001China Department of Respiratory Diseases Peking University First HospitalBeijing 100034China Department of Respiratory Diseases Peking University Third HospitalBeijing 100191China Department of Respiratory Diseases Henan Provincial People’s HospitalZhengzhouHenan 450003China Department of Respiratory Diseases Second Affiliated Hospita1 of Shanxi Medical UniversityTaiyuanShanxi 030001China Department of Respiratory Diseases First Affiliated Hospital of Fujian Medical UniversityFuzhouFuiian 350005China Department of Respiratory Diseases Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologywuhanHubei 430022China Department of Respiratory Diseases Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030 China guangzhou Institute of Respiratory Disease.First Affiliated Hospital of guangzhou Medical College GuangzhouGuangdong 510120China Department of Respiratory Diseases Guangxi Zhuang Autonomous Region People’s HospitalNanningGuangxi 530021China Department of Respiratory Diseases Central Hospita1 of Shenyang Medical College ShenyangLiaoning 110024China Department of Respiratory Diseases Beijing Gongan HospitalBeijing 100006China Department of Respiratory Diseases Jiangsu Senility HospitalNanjingJiangsu 210024China Department of Respiratory Diseases Afiliated Hospita1 of Ningxi

Background The nocturnal nondipping and elevated morning blood pressure （BP） in patients with obstructive sleep apnea syndrome （OSAS） have not yet been well investigated in Chinese patients. This study aimed to describe the BP profile, and to elucidate the relationships between daytime BP and nighttime BP, and between evening BP and morning BP in patients with OSAS. Methods Twenty teaching hospital sleep centers in China were organized by the Chinese Medical Association to participate in this study and 2297 patients were recruited between January 2004 and April 2006. BP assessments were made at four time points （daytime, evening, nighttime and morning） and polysomnography （PSG） was performed and subjects were classified into four groups by their apnea-hypopnea index （AHI）： control, n=213 with AHI 〈5; mild, n=420 with AHI -〉5 and 〈15; moderate, n=460 with AHI -〉15 and 〈30; and severe, n=1204 with AHI -〉30. SPSS 11.5 software package was used for statistical analysis and figure drawing. Results All the average daytime, nighttime, evening and morning BPs were positively correlated with AHI and negatively correlated with nadir nocturnal oxygen saturation. The ratios of nighttime/daytime and morning/evening average BP were positively correlated with AHI. The ratio of nighttime/daytime systolic BP became a ＂reversed BP dipping＂ pattern until the classification reached severe, while the ratio of nighttime/daytime diastolic BP became reversed at moderate. Similarly, the ratio of morning/evening diastolic BP becomes reversed even at mild. Conclusions OSAS may result in higher BP levels at all four time points. The ratios of nighttime/daytime and morning/evening BP increase with increased AHI. The increasing of diastolic BP, which is inclined to rise more quickly, is not parallel with increasing systolic BP.

关键词： obstructive sleep apnea syndrome blood pressure hypertension, dipping, polysomnography apnea-hypopnea index

Ni/MgO/Al_2O_3催化剂上以1-甲基萘为模型化合物高温焦炉煤气焦油的催化转化

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高等学校化学学报 2010年第9期31卷 1841-1847页

作者：杨军汪学广李林沈葵鲁雄刚丁伟中上海大学上海市现代冶金与材料制备重点实验室上海200072

采用共浸渍薄水铝石(AlOOH)方法制备了一系列Ni/MgO/Al2O3催化剂,并采用N2气吸附及X射线衍射等手段进行了表征.选择1-甲基萘作为焦油模型化合物,研究了该催化剂催化转化具有较低水蒸气/碳摩尔比(nH2O/nC)的高温焦炉煤气(COG)中焦油催化... 详细信息

采用共浸渍薄水铝石(AlOOH)方法制备了一系列Ni/MgO/Al2O3催化剂,并采用N2气吸附及X射线衍射等手段进行了表征.选择1-甲基萘作为焦油模型化合物,研究了该催化剂催化转化具有较低水蒸气/碳摩尔比(nH2O/nC)的高温焦炉煤气(COG)中焦油催化反应性能.考察了催化剂中MgO含量及反应条件等对催化剂性能的影响.实验结果表明,在775℃和nH2O/nC=0.7条件下,MgO改性的Ni/MgO/Al2O3催化剂对1-甲基萘催化转化为小分子气体反应具有较好的催化活性和稳定性;热重分析表明,MgO的加入能显著提高催化剂的抗积炭能力.在Ni/MgO/Al2O3催化剂上,反应气中高浓度H2S气体(0.25%,体积分数)能够促进焦油催化转化为小分子气体,这可能是由于H2S在Ni表面的可逆吸附形成更适合于重整反应的活性位,同时抑制了烷烃裂解吸附形成的碳在金属中的溶解、扩散并最终形成积炭过程.

关键词：镍催化剂 1-甲基萘焦炉煤气焦油催化转化

KINETIC STUDIES OF CATALYTIC OXIDATIVE COUPLING OF METHANE ON SERIES OF LiMO2 OXIDE

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Journal of Energy Chemistry 1993年第3期 258-261页

作者： LIN jun-Fan shen Cheng-Yu ZHANG Ye-Zhong Department of Chemistry, Nanjing University Nanjing, Jiangsu 210008

Using impregnation method, we synthesized several kinds of Li-doped transitionmetal oxide, LiMO2（M =Cr, Fe, Co, Ni, Zn and Al）, as catalysts for the oxidativecoupling of methane. We found that the Fe-50 catalyst with 50/50 molar ratio ofLi2O/Fe2O3, and Ni-20 with 20/80 molar ratio of Li2O/NiOxhad high activity. At800℃, the coversion of methane on Fe-50 was 43. 2%, C2yield was 21.5%. Ni-20 was a little less effective, the methane conversion and C2yield were 34% and14. 5% respectively.

关键词： Ni KINETIC STUDIES OF CATALYTIC OXIDATIVE COUPLING OF METHANE ON SERIES OF LiMO2 OXIDE OL