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Detection of blood AFPmRNA in nude mice bearing human HCC using nested RT-PCR and its significance

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World Journal of Gastroenterology 1998年第3期4卷 88-90页

作者： LIU Yang, ZHANG BaiHe, QIAN guangxiang, chen Han and WU MengChao

ＤｅｔｅｃｔｉｏｎｏｆｂｌｏｏｄＡＦＰｍＲＮＡｉｎｎｕｄｅｍｉｃｅｂｅａｒｉｎｇｈｕｍａｎＨＣＣｕｓｉｎｇｎｅｓｔｅｄＲＴＰＣＲａｎｄｉｔｓｓｉｇｎｉｆｉｃａｎｃｅＬＩＵＹａｎｇ，ＺＨＡＮＧＢａｉＨｅ，ＱＩＡＮＧ... 详细信息

ＤｅｔｅｃｔｉｏｎｏｆｂｌｏｏｄＡＦＰｍＲＮＡｉｎｎｕｄｅｍｉｃｅｂｅａｒｉｎｇｈｕｍａｎＨＣＣｕｓｉｎｇｎｅｓｔｅｄＲＴＰＣＲａｎｄｉｔｓｓｉｇｎｉｆｉｃａｎｃｅＬＩＵＹａｎｇ，ＺＨＡＮＧＢａｉＨｅ，ＱＩＡＮＧｕａｎｇＸｉａｎｇ，ＣＨＥＮＨａ...

关键词： carcinoma, hepatocellular/pathology lung neoplasms/secondary kidney neoplasms/secondary alphafetoproteins/analysis RNA, messenger polymerase chain reaction

Acute paraplegia following embolization of spinal dural arteriovenous fistula

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Chinese Medical Journal 2011年第4期124卷 634-636页

作者： HUANG cheng-guang QI xiang-qian chen Huai-rui LU Li-quan WU Xiao-jun BAI Ru-lin LU Yi-cheng Department of Neurosurgery Shanghai Changzheng HospitalShanghai 200003 China

Embolization therapy has been used as the initial treatment for spinal dural arteriovenous fistula （SDAVF） only for certain patients or in certain medical institutions due to its minimal invasiveness, but the recurrence of embolization remains a clinical challenge. The recurrent patient usually exhibits a gradual onset of symptoms and progressive deterioration of neurological function. Developing paraplegia several hours after embolization is commonly seen in patients with venous thrombosis-related complications, for which anticoagulation therapy is often administered. This article reports on a SDAVF patient who had weakness of both lower extremities before embolization and developed complete paraplegia several hours after embolization therapy, later confirmed by angiography as fistula recurrence. The symptoms were relieved gradually after second embolization. The pathophysiology of this patient is also discussed.

关键词： spinal cord arteriovenous fistula paraplegia embolization, therapeutic recurrence

A method of percutaneous vertebroplasty under the guidance of two C-arm fluoroscopes

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A method of percutaneous vertebroplasty under the guidance o...

A method of percutaneous vertebroplasty under the guidance of two C-arm fluoroscopes

2016年浙江省骨科学学术年会

作者： Ren-Jie Xu Yong-Qing Yan guang-xiang chen Tian-Ming Zou Xiao-Qiang Cai Dong-Lai Wang

Objective:To compare the clinical application in the percutaneous vertebroplasty under the guidance ofone or two C-arm ***:One hundred forty three elderly patients with Osteoporotic vertebral compression fractures(OVCFs) underwent percutaneous vertebroplasty under the guidance of one or two C-arm *** number of pulsed imagings,the time of operation and the incidence of cement leakage were ***:The average number of pulsed imagings was 16.00±1.58 vs 13.07±2.00 per patient under theguidance of one vs two C-arm *** average time of operation was 48.42±5.00 minutes vs39.70±7.42 minutes per patient under the guidance of one vs two C-arm *** incidenceof cement leakage was 20%vs 15.7%of the patients under the guidance of one vs two C-arm *** differences in the number of pulsed imagings and the time of operation were statistically *** difference in incidence of cement leakage was not statistically ***:The two-fluoroscopic technique reduce the labor cost,the radiation,the time of operationand the operation risk.

关键词： Osteoporotic vertebral compression fractures Percutaneous vertebroplasty Two C-arm fluoroscopes

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A method of percutaneous vertebroplasty under the guidance o...

三相四线制四桥臂型SiC MOSFET换流器研究

2015年浙江省骨科学学术年会

作者： Ren-Jie Xu Yong-Qing Yan guang-xiang chen Tian-Ming Zou Xiao-Qiang Cai Dong-Lai Wang

Objective:To compare the clinical application in the percutaneous vertebroplasty under the guidance of one or two C-arm ***:One hundred forty three elderly patients with Osteoporotic vertebral compression fractures(OVCFs)underwent percutaneous vertebroplasty under the guidance of one or two C-arm *** number of pulsed imagings,the time of operation and the incidence of cement leakage were ***:The average number of pulsed imagings was 16.00±1.58 vs 13.07±2.00 per patient under the guidance of one vs two C-arm *** average time of operation was 48.42±5.00 minutes vs 39.70±7.42 minutes per patient under the guidance of one vs two C-arm *** incidence of cement leakage was 20%vs 15.7%of the patients under the guidance of one vs two C-arm *** differences in the number of pulsed imagings and the time of operation were statistically *** difference in incidence of cement leakage was not statistically ***:The two-fluoroscopic technique reduce the labor cost,the radiation,the time of operation and the operation risk.

关键词： Osteoporotic vertebral compression fractures Percutaneous vertebroplasty Two C-arm fluoroscopes

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电力电子技术 2017年第9期51卷 42-44页

作者：李向奎秦广涛黄光政樊相臣国网济南供电公司山东济南250000 东北电力大学吉林吉林132012 国网山东节能服务有限公司山东济南250000

三相四线制换流器能实现低压配电网三相不平衡等综合电能质量调节,在此结合碳化硅(SiC)金属-氧化物半导体场效应晶体管(MOSFET)对四桥臂型两电平换流器展开深入研究。根据正弦脉宽调制(SPWM)下开关频率及电流波纹的大小来优化设计高频L... 详细信息

三相四线制换流器能实现低压配电网三相不平衡等综合电能质量调节,在此结合碳化硅(SiC)金属-氧化物半导体场效应晶体管(MOSFET)对四桥臂型两电平换流器展开深入研究。根据正弦脉宽调制(SPWM)下开关频率及电流波纹的大小来优化设计高频LC滤波器,通过效率分析和热等效电路来选取散热器。通过搭建并测试125 kVA三相四线制SiC MOSFET换流器实验装置来验证不同负载条件下设计合理性和SiC-MOSFET优越性。

关键词：换流器碳化硅金属-氧化物半导体场效应晶体管

Laparoscopic liver resection utilizing the ventral avascular area of the inferior vena cava:A retrospective cohort study

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World Journal of Gastroenterology 2025年第1期31卷 42-57页

作者： Kun Huang Zhu chen Heng Xiao Hai-Yang Hu Xing-Yu chen cheng-You Du xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400000China Department of General Surgery Mianyang Hospital of Traditional Chinese MedicineMianyang 621000Sichuan ProvinceChina

BACKGROUND Laparoscopic liver resection(LLR)can be challenging due to the difficulty of establishing a retrohepatic tunnel under *** the third hepatic hilum before parenchymal transection often leads to significant liver mobilization,tumor compression,and bleeding from the short hepatic veins(SHVs).This study introduces a novel technique utilizing the ventral avascular area of the inferior vena cava(IVC),allowing SHVs to be addressed after parenchymal transection,thereby reducing surgical complexity and improving outcomes in in situ *** To introduce and evaluate a novel LLR technique using the ventral avascular area of the IVC and compare its short-term outcomes with conventional *** The clinical cohort data of patients with pathologically confirmed hepatocellular carcinoma or intrahepatic cholangiocarcinoma who underwent conventional LLR and novel LLR between July 2021 and July 2023 at the First Affiliated Hospital of Chongqing Medical University were retrospectively *** novel LLR,we initially separated the caudate lobe from the IVC using dissecting forceps along the ventral avascular area of the ***,we transected the parenchyma of the left and right caudate lobes from the caudal side to the cephalic side using the avascular area as a ***,we addressed the SHVs and finally dissected the root of the right hepatic vein or left hepatic *** short-term postoperative outcomes and oncological results of the two approaches were evaluated and *** A total of 256 patients were included,with 150(58.59%)undergoing conventional LLR and 106(41.41%)undergoing novel *** novel technique resulted in significantly larger tumor resections(6.47±2.96 cm vs 4.01±2.33 cm,P<0.001),shorter operative times(199.57±60.37 minutes vs 262.33±83.90 minutes,P<0.001),less intraoperative blood loss(206.92±37.09 mL vs 363.34±131.27 mL,P<0.001),and greater resection volume(345.11±31.40 mL vs 264.38±31.98 mL,P<0.001)comp

关键词： Laparoscopic liver resection Inferior vena cava Retrohepatic tunnel Short hepatic veins Complex liver tumors Intraoperative bleeding control

Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

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Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： Xiaoqin Li Jian xiang Lu Qiu Xiaohan chen Yinkun Zhao Yujue Wang Qu Yue Taotao Gao Wenlong Liu Dan Xiao Zhaoyu Jin Panpan Li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and Biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation

四川龙门山铜尾矿库植被调查及植被恢复的物种选择探讨

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四川师范大学学报（自然科学版） 2009年第6期32卷 796-802页

作者：宗浩苏光麒张翔陈施羽四川师范大学生命科学学院四川成都610066

通过龙门山铜尾矿库土壤和植物重金属含量测定、植被调查、综合优势比分析,据此进行了该尾矿库植被恢复的植物群落重建方法的尝试.结果表明:尾矿土Cu、Pb、Zn含量分别为1319、901、209mg/kg;Cu超过植物生长临界值19.13倍,Pb超过14.48倍... 详细信息

通过龙门山铜尾矿库土壤和植物重金属含量测定、植被调查、综合优势比分析,据此进行了该尾矿库植被恢复的植物群落重建方法的尝试.结果表明:尾矿土Cu、Pb、Zn含量分别为1319、901、209mg/kg;Cu超过植物生长临界值19.13倍,Pb超过14.48倍,Zn超过5倍.尾矿土重金属含量平均比附近的耕地高25.05倍,铜含量高32.05倍,过高的重金属含量是限制植物在尾矿地定居的主要因子.将该库91种植物分为5个相对稳定的群落类型:葫芦藓+地钱群落;艾蒿群落;白车轴草群落;芭茅+羊耳菊群落;羊耳菊+千里光+密蒙花群落.植物中早熟禾、狗牙根、翦股颖体内Cu和Pb含量均>100mg/kg,为铜和铅的累积植物.最终筛选确定白车轴草、早熟禾、芭茅、棒头草、狗尾草、马桑作为植被重建的优良先锋物种.植物在纯尾沙上长势低弱,难以或不适应立地条件.经过覆盖耕地土处理效果明显好之,植物表现出对土壤条件的适应性;施肥对于生长在尾砂土上的植物作用微弱,却对覆盖耕地土上生长的植物产生了明显的成效.

关键词：龙门山铜矿尾矿库植被调查先锋植物植被恢复与重建

Mutual regulation of microglia and astrocytes after Gas6 inhibits spinal cord injury

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Neural Regeneration Research 2025年第2期20卷 557-573页

作者： Jiewen chen Xiaolin Zeng Le Wang Wenwu Zhang Gang Li Xing cheng Peiqiang Su Yong Wan xiang Li Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina guangdong Province Key Laboratory of Orthopedics and Traumatology GuangzhouGuangdong ProvinceChina

Invasive inflammation and excessive scar formation are the main reasons for the difficulty in repairing nervous tissue after spinal cord *** and astrocytes play key roles in the spinal cord injury micro-environment and share a close ***,the mechanisms involved remain *** this study,we found that after spinal cord injury,resting microglia(M0)were polarized into pro-inflammatory phenotypes(MG1 and MG3),while resting astrocytes were polarized into reactive and scar-forming *** expression of growth arrest-specific 6(Gas6)and its receptor Axl were significantly down-regulated in microglia and astrocytes after spinal cord *** vitro experiments showed that Gas6 had negative effects on the polarization of reactive astrocytes and pro-inflammatory microglia,and even inhibited the cross-regulation between *** further demonstrated that Gas6 can inhibit the polarization of reactive astrocytes by suppressing the activation of the Yes-associated protein signaling ***,in turn,inhibited the polarization of pro-inflammatory microglia by suppressing the activation of the nuclear factor-κB/p65 and Janus kinase/signal transducer and activator of transcription signaling *** vivo experiments showed that Gas6 inhibited the polarization of pro-inflammatory microglia and reactive astrocytes in the injured spinal cord,thereby promoting tissue repair and motor function ***,Gas6 may play a role in the treatment of spinal cord *** can inhibit the inflammatory pathway of microglia and polarization of astrocytes,attenuate the interaction between microglia and astrocytes in the inflammatory microenvironment,and thereby alleviate local inflammation and reduce scar formation in the spinal cord.

关键词： astrocytes Axl cell polarization Gas6 Hippo signal inflammatory micro-environment intercellular interaction microglia single-cell sequencing spinal cord injury