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To be or not to be direct:The role of neuromedin U in neuro-eosinophil crosstalk

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Science Bulletin 2024年第2期69卷 148-150页

作者： Ruichao liu Wenhao Shao jun Xu Coco Chu SXMU-Tsinghua Collaborative Innovation Center for Frontier Medicine Taiyuan 030001China Insttute for Immunogy Department of Basic Medical SciencesSchool of Medicinesinghua UnierstyBejing 100084China Tsinghua-Peking Center for Life Sciences Tsinghua UniversityBeijing 100084China Shanxi Medical University Taiyuan 030012China Department of Surgery First Hospital of Shanxi Medical UniversityShanxi Provincial Key Laboratory for Digestive Diseases and Organ TransplantationTaiyuan 030001China Beijing Key Laboratory for Immunological Research on Chronic Diseases Tsinghua UniversityBejing 100084China

With the development of new experimental techniques(e.g.,single-cell RNA sequencing(scRNA-seq),light sheet microscopy,and clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9),emerging studies have begun to uncover the interactions between the nervous system and the immune system,both in health and *** example,in mucosal tissues such as the lung and the intestine,neurotransmitters including acetylcholine[1]and adrenaline[2]can directly regulate the immune cell functions thus affect the results of allergy,asthma,and anti-pathogen host defense[3].

关键词： intestine lung asthma

Effects of rare earth elements on inclusions, microstructure and impact toughness of spring steel

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Journal of Iron and Steel Research(International) 2024年第4期31卷 933-944页

作者： Chun-lei Hao Chao-yun Yang Peng liu Yi-kun Luan Bao-guang Sang Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina School of Mechanical Engineering and Automation Dalian Polytechnic UniversityDalian 116034LiaoningChina

Spring steel is an indispensable basic part manufacturing material in mechanical equipment,which is widely used in transportation tools such as automobiles,railways,construction machinery and other *** effects of rare earth(RE)on inclusions,microstructure,carbides and impact toughness of 50CrV spring steel were studied by means of optical microscope,scanning electron microscope,transmission electron microscope and impact *** results show that the addition of rare earth can modify the main MnS and Al_(2)O_(3) inclusions in steel to form spherical or near-spherical rare earth inclusions,and the size of inclusions is significantly *** the quenched structure,the size of martensite slab becomes smaller and the structure is *** tempering,the carbide changes from sheet to ellipse,which makes it easier for spring steel to form stress concentration cracks under *** becomes finer and more dispersed,which leads to better pinning of grain boundaries and smaller grain *** impact toughness of 50CrV-RE spring steel increased from 21 to 41 J by 95%due to the improvement of inclusions,microstructure and carbides by rare *** is possible to improve the strength and toughness of spring steel for the improvement of railway running speed and the development of vehicle lightweight in China.

关键词： Rare earth-Spring steel Inclusion Microstructure Impact toughness

Two-layer Lagrange-based relay network topology and trajectory design for solar system explorations

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Science China(Information Sciences) 2024年第6期67卷 342-358页

作者： jun CAO Jian JIAO Hao liu Rongxing LU Qinyu ZHANG guangdong Provincial Key Laboratory of Aerospace Communication and Networking Technology Harbin Institute of Technology (Shenzhen) Faculty of Computer Science (FCS) University of New Brunswick

Exploration targeting outer planets and even the edge of the solar system is an emerging direction for the deep-space exploration in the next decades. To address this challenge, a novel two-layer Lagrangebased relay network topology is proposed in this study. Specifically, we utilize the Sun-Mars and Sun-Saturn Lagrange points(LPs) L4 and L5 to build a two-layer backbone relay network, which ensures continuous and high-efficiency communication capability for the exploration of the solar system. Furthermore, we utilize the planetary gravity assist and design the transfer trajectory of backbone relays with the help of planetary celestial body motion equations and Kepler's laws. Moreover, we conduct link budget analysis for multihop relay transmission under Gamma-Gamma distribution, shadowed Rician fading, and additive white Gaussian noise channels in several typical exploration scenarios and validate that the LP relays can effectively support future deep-space exploration missions.

关键词： deep-space communication Lagrangian points backbone relay network transfer trajectory relay selection

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Experimental investigation on using CO_(2)/H_(2)O emulsion with high water cut in enhanced oil recovery

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Petroleum Science 2024年第2期21卷 974-986页

作者： Xi-Dao Wu Peng Xiao Bei liu guang-Jin Chen Jian-Hua Pang State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing102249China Ocean Intelligence Technology Center Shenzhen Institute of Guangdong Ocean UniversityShenzhen518120GuangdongChina

CO_(2) emulsions used for EOR have received a lot of interest because of its good performance on CO_(2)mobility ***,most of them have been focusing on the high quality CO_(2) emulsion(high CO_(2) fraction),while CO_(2) emulsion with high water cut has been rarely *** this paper,we carried out a comprehensive experimental study of using high water cut CO_(2)/H_(2)O emulsion for enhancing oil ***,a nonionic surfactant,alkyl glycosides(APG),was selected to stabilize CO_(2)/H_(2)O emulsion,and the corresponding morphology and stability were evaluated with a transparent PVT ***,plugging capacity and apparent viscosity of CO_(2)/H_(2)O emulsion were measured systematically by a sand pack displacement apparatus connected with a 1.95-m long capillary ***,a high water cut(40 vol%) CO_(2)/H_(2)O emulsion was selected for flooding experiments in a long sand pack and a core sample,and the oil recovery,the rate of oil recovery,and the pressure gradients were *** results indicated that APG had a good performance on emulsifying and stabilizing CO_(2) *** inversion from H_(2)O/CO_(2) emulsion to CO_(2)/H_(2)O emulsion with the increase in water cut was ***_(2)/H_(2)O emulsions with lower water cuts presented higher apparent viscosity,while the optimal plugging capacity of CO_(2)/H_(2)O emulsion occurred at a certain water ***,the displacement using CO_(2)/H_(2)O emulsion provided 18.98% and 13.36% additional oil recovery than that using pure CO_(2) in long sand pack and core tests,*** work may provide guidelines for EOR using CO_(2) emulsions with high water cut.

关键词： CO_(2)/H_(2)O emulsion High water cut CO_(2) mobility control Enhanced oil recovery

Transient state analysis of a rub-impact rotor system during maneuvering flight

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Chinese Journal of Aeronautics 2024年第7期37卷 236-251页

作者： jun WANG Yunfei liu Zhaoye QIN Liang MA Fulei CHU Beijing Key Laboratory of Health Monitoring and Self-Recovery for High-End Machinery Equipment Beijing University of Chemical TechnologyBeijing 100029China State Key Laboratory of Tribology Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China College of Aeronautical Engineering Civil Aviation University of ChinaTianjin 300300China

Maneuvering flight substantially affects the dynamic behavior of rotors;particularly,such flight may cause rubbing between a rotor and stator,which is one of the most serious damages in aircraft *** this paper,a nonlinear dynamic model for describing the dynamic characteristics of a rub-impact rotor system during maneuvering flight is established based on the Lagrange ***,numerical simulations employing the Newmark method are performed,delving into the detailed discussion of the influence of parameters such as rotational speed and maneuvering flight on the transient and steady-state responses of the rotor *** effect mechanism of maneuver load and its coupling with rub impact is *** results show that the impact response induced by maneuvering flight is more obvious in the subcritical state than in the supercritical *** additional stiffness and damping are also induced;in particular,the additional damping has a coupling ***,the rub impact imposes an additional constraint on the rotor system,thereby weakening the influence of the maneuver load and becoming the major factor that determines the dynamic behavior of the rotor system at high speeds.

关键词： Maneuvering flight Rub impact Rotor system Dynamic response Impact response

Artificial intelligence for the detection of glaucoma with SD-OCT images:a systematic review and Meta-analysis

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 408-419页

作者： Nan-Nan Shi Jing Li guang-Hui liu Ming-Fang Cao Department of Ophthalmology Affiliated People’s Hospital(Fujian Provincial People’s Hospital)Fujian University of Traditional Chinese MedicineFuzhou 350004Fujian ProvinceChina Eye Institute of Integrated Chinese and Western Medicine Fujian University of Traditional Chinese MedicineFuzhou 350004Fujian ProvinceChina

●AIM:To quantify the performance of artificial intelligence(AI)in detecting glaucoma with spectral-domain optical coherence tomography(SD-OCT)images.●METHODS:Electronic databases including PubMed,Embase,Scopus,ScienceDirect,ProQuest and Cochrane Library were searched before May 31,2023 which adopted AI for glaucoma detection with SD-OCT *** pieces of the literature were screened and extracted by two ***-analysis,Meta-regression,subgroup,and publication of bias were conducted by *** risk of bias assessment was performed in Revman5.4 using the QUADAS-2 tool.●RESULTS:Twenty studies and 51 models were selected for systematic review and *** pooled sensitivity and specificity were 0.91(95%CI:0.86–0.94,I2=94.67%),0.90(95%CI:0.87–0.92,I2=89.24%).The pooled positive likelihood ratio(PLR)and negative likelihood ratio(NLR)were 8.79(95%CI:6.93–11.15,I2=89.31%)and 0.11(95%CI:0.07–0.16,I2=95.25%).The pooled diagnostic odds ratio(DOR)and area under curve(AUC)were 83.58(95%CI:47.15–148.15,I2=100%)and 0.95(95%CI:0.93–0.97).There was no threshold effect(Spearman correlation coefficient=0.22,P>0.05).●CONCLUSION:There is a high accuracy for the detection of glaucoma with AI with SD-OCT *** application of AI-based algorithms allows together with“doctor+artificial intelligence”to improve the diagnosis of glaucoma.

关键词： artificial intelligence spectral-domain optical coherence tomography glaucoma Meta-analysis

Unstructured Road Extraction in UAV Images based on Lightweight Model

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Chinese Journal of Mechanical Engineering 2024年第2期37卷 372-384页

作者： Di Zhang Qichao An Xiaoxue Feng Ronghua liu jun Han Feng Pan School of Automation Beijing Institute of TechnologyBeijing 100081China Tianjin Institute of Maritime Navigation Instruments Tianjin 300130China The 716th Research Institute of China Shipbuilding Group Co. LtdJiangsu 222061China

There is no unified planning standard for unstructured roads,and the morphological structures of these roads are complex and *** is important to maintain a balance between accuracy and speed for unstructured road extraction *** road extraction algorithms based on deep learning have problems such as high model complexity,high computational cost,and the inability to adapt to current edge computing ***,it is best to use lightweight network *** the need for lightweight models and the characteristics of unstructured roads with different pattern shapes,such as blocks and strips,a TMB(Triple Multi-Block)feature extraction module is proposed,and the overall structure of the TMBNet network is *** TMB module was compared with SS-nbt,Non-bottleneck-1D,and other modules via *** feasibility and effectiveness of the TMB module design were proven through experiments and *** comparison experiment,using multiple convolution kernel categories,proved that the TMB module can improve the segmentation accuracy of the *** comparison with different semantic segmentation networks demonstrates that the TMBNet network has advantages in terms of unstructured road extraction.

关键词： Unstructured road Lightweight model Triple Multi-Block(TMB) Semantic segmentation net

Research progress of carbon-based particle electrodes in three-dimensional electrode reactors for wastewater treatment

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新型炭材料(中英文) 2024年

作者： LU Hua-yu liu Wei-feng QIN Lei liu Xu-guang Institute of New Carbon Materials College of Materials Science and Engineering Taiyuan University of Technology Key Laboratory of Interface Science and Engineering in Advanced Materials (Taiyuan University of Technology) Ministry of Education Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering

Three-dimensional(3D) electrode technology is a competitive water treatment technology owing to its high catalytic efficiency, low energy consumption, and promising development. The introduction of a third electrode on the basis of a 2D electrode system forms a 3D electrode system, and the introduced third electrode is also known as the particle electrode. Particle electrodes in3D electrode system are generally in the form of particles or crumbs that be filled in between the cathode and anode. The core of the3D electrode system is the particle electrode, so the selection of particle electrode materials is the focus of the research of 3D electrode technology. Carbon-based materials are widely used as particle electrodes in 3D electrode technology because of their advantages of large specific surface area, good adsorption performance, high chemical stability, and low price. In this review, the research progress of carbon-based materials as particle electrodes for degrading organic pollutants in recent years is collected, the principle of3D electrode technology is introduced, along with the classification of particle electrodes and the current research status of carbonbased particle electrodes, and the challenges and future development of carbon-based particle electrodes in wastewater treatment are summarized.

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Asymptotic Inference in the Random Coefficient Autoregressive Model with Time-functional Variance Noises

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 320-346页

作者： En-wen ZHU Zi-wei DENG Han-jun ZHANG jun CAO Xiao-hui liu Department of Mathematics and Statistics Changsha University of Science and TechnologyChangsha 410114China School of Mathematics and Computational Science Xiangtan UniversityXiangtan 411105China School of Statistics and Data Science and Key Laboratory of Data Science in Finance and EconomicsJiangxi University of Finance and EconomicsNanchang 330013China

This paper considers the random coefficient autoregressive model with time-functional variance noises,hereafter the RCA-TFV *** first establish the consistency and asymptotic normality of the conditional least squares estimator for the constant *** semiparametric least squares estimator for the variance of the random coefficient and the nonparametric estimator for the variance function are constructed,and their asymptotic results are reported.A simulation study is presented along with an analysis of real data to assess the performance of our method in finite samples.

关键词： random coefficient autoregressive model time-functional variance conditional least squares semiparametric least squares