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Improving Film Cooling Performance by Using One-Inlet and Double-Outlet Hole

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Journal of Thermal Science 2010年第5期19卷 430-437页

作者： guang-chao li and Wei Zhang Aeroengine and Energy Engineering College,Shenyang Areospace University Shenyang China 110136 Aeroengine and Energy Engineering College Shenyang Areospace University Shenyang China

The film cooling performance of a trunk-branch hole is investigated by numerical simulation in this paper. The geometry of the hole is a novel cooling concept, which controls the vortices-pair existing at the mink hole outlet using the injection of the branch hole. The trunk-branch holes require easily machinable round hole as compared to the shaped holes. The flow cases were considered at the blowing ratios of 0.5, 0.75, 1.0, 1.5 and 2.0. At the low blowing ratio of 0.5, the vortices-pair at the outlet of the trunk hole is reduced and the laterally coverage of the film is improved. At the high blowing ratio of 2.0, the vortices-pair is killed by the vortex which is produced by the injection of the branch hole. The flow rate of the two outlets becomes more significantly different when the blowing ratio increases from 0.75 to 2.0. The discharge coefficients increase 0.15 and the laterally averaged film effectiveness improve 0.2 as compared to the cylindrical holes. The optimal blowing ratios occur at M=1.0 or M= 1.5 according to the various locations downstream of the holes.

关键词： aerospace propulsion system gas turbine film cooling heat transfer

Effect of 37Cl enrichment on neutrons in a molten chloride salt fast reactor

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Nuclear Science and Techniques 2020年第3期31卷 45-56页

作者： liao-Yuan He guang-chao li Shao-Peng Xia Jin-Gen Chen Yang Zou Gui-Min liu University of Chinese Academy of Sciences Beijing 100049China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China CAS Innovative Academies in TMSR Energy System Shanghai 201800China Institute of Nuclear and New Energy Technology Tsinghua UniversityBeijing 100084China

A molten chloride salt fast reactor(MCFR)is well suited to fuel breeding and the transmutation of transuranium(TRU)elements owing to its advantageous features of fast neutron spectrum and high TRU ***,the neutron absorption cross section of 35Cl is approximately 1000 times greater than for 37Cl,which has a significant impact on the neutron physical characteristics of a *** on an automatic online refueling and reprocessing procedure,the influences of 37Cl enrichment on neutron economy,breeding performance,and the production of harmful nuclides were *** show that 37Cl enrichment strongly influences the neutron properties of a *** natural chlorine,233U breeding cannot be achieved and the yields of S and 36Cl are very *** the 37Cl enrichment to 97%brings a clear improvement in its neutronics property,making it almost equal to that corresponding to 100%***,when 37Cl is enriched to 99%,its neutronics parameters are almost the same as for 100%*** the enrichment cost and the neutron properties,a 37Cl enrichment of 97%is *** an optimal neutronics performance requires 99%37Cl enrichment.

关键词： Molten salt reactor Molten chlorine salt fast reactor 37Cl enrichment Th-U fuel breeding

Ultrathin porous graphitic carbon nanosheets activated by alkali metal salts for high power density lithium-ion capacitors

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Rare Metals 2020年第12期39卷 1364-1373页

作者： Yu-Qing Dai guang-chao li Xin-Hai li Hua-Jun Guo Zhi-Xing Wang Guo-Chun Yan Jie-Xi Wang School of Metallurgy and Environment&College of Chemistry and Chemical Engineering Central South UniversityChangsha410083China Engineering Research Center of the Ministry of Education for Advanced Battery Materials School of Metallurgy and Environment&College of Chemistry and Chemical EngineeringChangsha410083China

Graphitic carbons with reasonable pore volume and appropriate graphitization degree can provide efficient li+/electrolyte-transfer channels and ameliorate the sluggish dynamic behavior of battery-type carbon negative electrode in lithium-ion capacitors(liCs).In this work,onion-like graphitic carbon materials are obtained by using carbon quantum dots as precursors after sintering,and the effects of alkali metal salts on the structure,morphology and performance of the samples are *** results show that alkali metal salts as activator can etch graphitic carbons,and the specific surface area and pore size distribution are intimately related to the description of the alkali metal ***,it also affects the graphitization degree of the *** porous graphitic carbons(SGCs)obtained by NaCl activation exhibit high specific surface area(77.14 m^(2)·g^(-1))and appropriate graphitization *** is expectable that the electrochemical performance for lithium-ions storage can be largely promoted by the smart combination of catalytic graphitization and pores-creating ***-performance liCs(S-GCs//AC liCs)are achieved with high energy density of 92 Wh·kg^(-1)and superior rate capability(66.3 Wh·kg^(-1)at10 A·g^(-1))together with the power density as high as10020.2 W·kg^(-1).

关键词： Alkali metal salts activation Porous graphitic carbons Catalytic graphitization lithium-ion capacitors

P-modified cobalt oxide: A novel and effective catalyst for oxidative dehydrogenation of propane

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Chinese Chemical Letters 2013年第9期24卷 789-792页

作者： Xiao-Zhang lin guang-chao li Chuan-Jing Huang Wei-Zheng Weng Hui-lin Wan State Key Laboratory of Physical Chemistry of Solid Surfaces National Engineering Laboratory for Green Chemical Productions of Alcohols Ethers and Esters and Department of Chemistry College of Chemistry and Chemical Engineering Xiamen University

A series ofnanosized cobalt oxide catalysts modified with phosphorus have been synthesized by the solgel method and investigated in the oxidative dehydrogenation of propane to propene. With the addition of phosphorus, the crystallite size of the catalyst was largely decreased, while the P species in the catalyst were highly dispersed. Compared to pure cobalt oxide, the P-modified samples showed higher propane conversion and enhanced propene selectivity. Over the PCoO catalyst with a P/Co atomic ratio of 0.05, the maximal propene yields of 15.7% with a propane conversion of 28.3% were obtained at 520 ℃.

关键词： Propane Propene Oxidative dehydrogenation Nanosized PCoO catalyst

Technological Characters and Improvements on Type SLC-S Precalciner Kiln

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Journal of Wuhan University of Technology(Materials Science) 2001年第2期16卷 69-72页

作者：胡曙光 Wuhan University of Technology Wuhan 430070 China

In this paper the problems on SP kiln period is discussed, whichlead to low CaCO_3 decarbon- ation rate in the hot meal, so that kilncoating is vulnerable and material frequently falls off and blocksthe pre- heater. Excellent effects are achieved when skipping the SPkiln period, neglecting the function of the dividing gate below theC4 preheater and sending the material completely into the calciner.

关键词： precalciner character improvement

环糊精手性色谱柱HPLC同时测定酒石酸布托啡诺注射液中酒石酸布托啡诺及其右旋异构体和苄索氯铵的含量

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中国药学杂志 2016年第19期51卷 1695-1698页

作者：裴琳王立云卢京光王超李新荣青岛市食品药品检验研究院山东青岛266071

目的建立环糊精手性色谱柱HPLC同时测定酒石酸布托啡诺注射液中酒石酸布托啡诺、右旋异构体和抑菌剂苄索氯铵的含量。方法采用Astec CyclobondⅡ环糊精手性色谱柱(4.6 mm×250 mm,5μm),流动相:0.05 mol·L^(-1)醋酸铵溶液(冰乙酸调节p... 详细信息

目的建立环糊精手性色谱柱HPLC同时测定酒石酸布托啡诺注射液中酒石酸布托啡诺、右旋异构体和抑菌剂苄索氯铵的含量。方法采用Astec CyclobondⅡ环糊精手性色谱柱(4.6 mm×250 mm,5μm),流动相:0.05 mol·L^(-1)醋酸铵溶液(冰乙酸调节pH值为4.1)(A)-乙腈(B)梯度洗脱;检测波长:280 nm;流速:1.0 mL·min^(-1);紫外检测器。结果 3种待测组分线性关系良好,酒石酸布托啡诺线性范围为0.04~2.0 mg·mL^(-1)(r=0.999 9),平均加样回收率为100.2%;右旋异构体线性范围为0.01~2.0 mg·mL^(-1)(r=1.000),平均加样回收率为100.7%;苄索氯铵线性范围为0.02~1.0 mg·mL^(-1)(r=0.999 9),平均加样回收率为99.4%。结论该方法简便、准确,重复性好,可用于酒石酸布托啡诺注射液的质量控制。

关键词：高效液相色谱法环糊精手性色谱柱酒石酸布托啡诺异构体抑菌剂苄索氯铵

Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang li Xiaomei Tang Jinyu Zeng Yige Song chao Xu Kai Zhao Guoqiang liu Youming Lu Xinyan li Kai Shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate Student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury

Small extracellular vesicles derived from cerebral endothelial cells with elevated microRNA 27a promote ischemic stroke recovery

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Neural Regeneration Research 2025年第1期20卷 224-233页

作者： Yi Zhang Zhongwu liu Michael Chopp Michael Millman Yanfeng li Pasquale Cepparulo Amy Kemper chao li li Zhang Zheng Gang Zhang Department of Neurology Henry Ford HospitalDetroitMIUSA Department of Physics Oakland UniversityRochesterMIUSA Department of Pathology Henry Ford HospitalDetroitMIUSA Division of Pharmacology Department of NeuroscienceReproductive and Dentistry SciencesSchool of MedicineUniversity of Naples“Federico Ⅱ”NaplesItaly

Axonal remodeling is a critical aspect of ischemic brain repair processes and contributes to spontaneous functional *** previous in vitro study demonstrated that exosomes/small extracellular vesicles(sEVs)isolated from cerebral endothelial cells(CEC-sEVs)of ischemic brain promote axonal growth of embryonic cortical neurons and that microRNA 27a(miR-27a)is an elevated miRNA in ischemic *** the present study,we investigated whether normal CEC-sEVs engineered to enrich their levels of miR-27a(27a-sEVs)further enhance axonal growth and improve neurological outcomes after ischemic stroke when compared with treatment with non-engineered CEC-sEVs.27a-sEVs were isolated from the conditioned medium of healthy mouse CECs transfected with a lentiviral miR-27a expression *** EVs isolated from CECs transfected with a scramble vector(Scra-sEVs)were used as a *** male mice were subjected to permanent middle cerebral artery occlusion and then were randomly treated with 27a-sEVs or *** array of behavior assays was used to measure neurological *** with treatment of ischemic stroke with Scra-sEVs,treatment with 27a-sEVs significantly augmented axons and spines in the peri-infarct zone and in the corticospinal tract of the spinal grey matter of the denervated side,and significantly improved neurological *** vitro studies demonstrated that CEC-sEVs carrying reduced miR-27a abolished 27a-sEV-augmented axonal *** analysis revealed that 27a-sEVs systemically administered preferentially localized to the pre-synaptic active zone,while quantitative reverse transcription-polymerase chain reaction and Western Blot analysis showed elevated miR-27a,and reduced axonal inhibitory proteins Semaphorin 6A and Ras Homolog Family Member A in the peri-infarct *** of the Clathrin-dependent endocytosis pathway substantially reduced neuronal internalization of *** data provide evidence that 27a-sEVs have

关键词： axonal remodeling cerebral endothelial cells exosomes miR-27a mitochondria Semaphorin 6A small extracellular vesicles stroke

Protein-based functional hydrogel improves cutaneous nerve repair and diabetic wound healing

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Nano Research 2025年第1期18卷 586-596页

作者： Hanzhi Lu Mingrui Cui Yi Wang Xinran Du Xinyi Zhou Yuhan Fang Xiaoyan Gao Ying Peng Jianyong Zhu guang Yang Fulun li Department of Dermatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine College of Biological Science and Medical EngineeringDonghua UniversityShanghai 201620China Clinical Laboratory Medicine Center Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China

Cutaneous nerve regeneration in diabetic wounds remains a challenge for current clinical ***,a natural protein-based functional hydrogel is developed using keratin as the sole matrix,and protocatechuic aldehyde(PA)and zinc ions as the building blocks through dual-dynamic crosslinking reactions of thiol-aldehyde addition and catecholzinc ions *** unique structural design endows the hydrogel with excellent injectability,skin adhesion,self-healing and antibacterial ability,and *** addition,this hydrogel acts as a drug carrier for the loading and sustained release of phellopterin(PP),a natural compound extracted from traditional Chinese medicine Angelica *** findings demonstrate that the PP-loaded hydrogel promotes cutaneous nerve regeneration,angiogenesis and tissue remodeling in the full-thickness wounds in both db/db and streptozotocin-induced C57BL/6 diabetic mice,notably by the synergistic effect of zinc ions and PP,showing a great potential in diabetic wound therapy.

关键词： functional hydrogel cutaneous nerve regeneration dynamic crosslinking diabetic wounds