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关节镜下半月板成形术与康复训练治疗中年退行性内侧半月板撕裂的疗效比较

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中华损伤与修复杂志（电子版） 2024年第2期19卷 134-140页

作者：韩伟峰王典陈艺丹曾峥首都医科大学附属北京天坛医院骨科 100070 首都医科大学附属北京天坛医院手术室 100070

目的对比分析关节镜下半月板成形术与康复治疗中年单纯退行性膝内侧半月板撕裂的临床疗效。方法回顾性分析2017年1月至2020年1月首都医科大学附属北京天坛医院骨科收治的90例中年内侧半月板撕裂患者资料,依据不同治疗方式,分为半月板成... 详细信息

目的对比分析关节镜下半月板成形术与康复治疗中年单纯退行性膝内侧半月板撕裂的临床疗效。方法回顾性分析2017年1月至2020年1月首都医科大学附属北京天坛医院骨科收治的90例中年内侧半月板撕裂患者资料,依据不同治疗方式,分为半月板成形组(48例),康复治疗组(42例),于术前、术后3个月、术后2年采集患者一般情况、膝关节功能评分量表(KOOS)、膝关节影像学评估(KL分级),比较两组患者的临床疗效。结果半月板成形组与康复治疗组在年龄、性别、体质量指数(BMI)方面组间差异无统计学意义;半月板成形组术前KOOS评分[(36.61±7.14)分]与康复治疗组[(36.7±11.59)分]相比差异无统计学意义;半月板成形组术后3个月KOOS评分[(64.3±14.39)分]显著高于康复治疗组[(44.65±1.66)分](P<0.05);半月板成形组术后2年KOOS评分[(71.2±14.37)分]与康复治疗组[(72.7±12.15)分]相比差异无统计学意义;术后2年膝骨关节炎进展半月板成形组(术前KL 0级3例,1级24例,2级21例;术后2年0级0例,1级12例,2级36例)显著快于康复治疗组(治疗前KL 0级4例,1级18例,2级20例;治疗后2年0级0例,1级16例,2级26例)(P<0.05)。结论相对于康复治疗方案,单纯退行性膝内侧半月板撕裂患者接受半月板成形术在早期可显著改善临床症状和膝关节功能,尤其是疼痛和日常生活能力,在中期临床随访中无显著差异,半月板成形术加速膝骨关节炎进展。与康复治疗相比,关节镜下半月板成形术治疗退行性膝内侧半月板撕裂并无明显优势,应采取谨慎态度。

关键词：半月板撕裂膝关节镜半月板成形康复

Staphylococcus aureus bacteremia and infective endocarditis in a patient with epidermolytic hyperkeratosis:A case report

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World Journal of Clinical Cases 2022年第36期10卷 13418-13425页

作者： Yu Chen dian Chen Hao Liu Chen-guang Zhang Lin-Lin Song Department of Emergency Beijing Tsinghua Changgung HospitalBeijing 102218China Department of Dermatology Beijing Tsinghua Changgung HospitalBeijing 102218China Department of Pathology Beijing Tsinghua Changgung HospitalBeijing 102218China

BACKGROUND Staphylococcus aureus bacteraemia(SAB)is among the leading causes of bacteraemia and infectious *** frequency of infectious endocarditis(IE)among SAB patients ranges from 5%to 10%-12%.In adults,the characteristics of epidermolytic hyperkeratosis(EHK)include hyperkeratosis,erosions,and *** with inflammatory skin diseases and some diseases involving the epidermis tend to exhibit a disturbed skin barrier and tend to have poor cellmediated *** SUMMARY We describe a case of SAB and infective endocarditis in a 43-year-old male who presented with fever of unknown origin and skin *** genetic tests,the skin disease was diagnosed as *** A breached skin barrier secondary to EHK,coupled with inadequate sanitation,likely provided the opportunity for bacterial seeding,leading to IE and deepseated abscess or organ *** may be associated with skin infection and multiple risk factors for extracutaneous *** with EHK should be treated early to minimize their *** patients with EHK present with prolonged fever of unknown origin,IE and organ abscesses should be ruled out,including metastatic spreads.

关键词： Staphylococcus aureus bacteremia Infective endocarditis Epidermolytic hyperkeratosis Case report

Online algorithms for scheduling with machine activation cost on two uniform machines

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第1期8卷 127-133页

作者： han Shu-guang JIANG Yi-wei HU Jue-liang Department of Mathematics Zhejiang University Hangzhou 310027 China Faculty of Science Zhej iang Sci- Tech University Hangzhou 310018 China

In this paper we investigate a variant of the scheduling problem on two uniform machines with speeds 1 and s. For this problem, we are given two potential uniform machines to process a sequence of independent jobs. Machines need to be activated before starting to process, and each machine activated incurs a fixed machine activation cost. No machines are initially activated, and when a job is revealed, the algorithm has the option to activate new machines. The objective is to minimize the sum of the makespan and the machine activation cost. We design optimal online algorithms with competitive ratio of (2s+1)/(s+1) for every s≥1.

关键词： Online algorithm Competitive analysis Uniform machine scheduling Machine activation cost

电解水制氢以及氢燃料电池用聚电解质阴离子交换膜的研究进展

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高分子通报 2024年第9期37卷 1210-1221页

作者：李佳纯韩晨光胡超魏天鹤贾妍张瑛中国石油大学(北京)新能源与材料学院北京102249

氢能是一种具有广阔应用前景的新能源,阴离子交换膜电解水制氢技术(AEMWE)与阴离子交换膜氢燃料电池技术(AEMFC)被认为是极具发展前景的氢能源技术,两者均需要聚电解质阴离子交换膜(AEM)。本综述首先概述了AEMWE和AEMFC技术原理,提出AE... 详细信息

氢能是一种具有广阔应用前景的新能源,阴离子交换膜电解水制氢技术(AEMWE)与阴离子交换膜氢燃料电池技术(AEMFC)被认为是极具发展前景的氢能源技术,两者均需要聚电解质阴离子交换膜(AEM)。本综述首先概述了AEMWE和AEMFC技术原理,提出AEM的技术要求,解释了AEM中OH^(-)的传输机制。接着根据主链结构的不同,重点对聚芳醚类、聚苯并咪唑类、聚苯烷撑类、聚烯烃类阴离子交换膜的研究进展进行了详细介绍,旨在为今后AEM的研发和设计提供思路。

关键词：氢能电解水制氢氢燃料电池聚电解质阴离子交换膜

Synthesis and Characterization of CdSe Nanocrystals Capped by CdS

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Chemical Research in Chinese Universities 2003年第3期19卷 269-274页

作者： SUXing-guang LINZhang-bi HUHai ZhanGJia-hua JINQin-han LaboratoryofExcitedStateProcesses ChineseAcademyofSciencesChangchun130021P.R.China CollegeofChemistry JilinUniversityChangchun130023P.R.China CollegeofChemistry JilinUniversityChangchun130023P.R.China LaboratoryofExcitedStateProcesses ChineseAcademyofSciencesChangchun130021P.R.China

CdSe semiconductor nanocrystals capped by CdS were synthesized in the aqueous solution with 2 mercaptoethanol as the stabilizer. The CdS capping with a higher band gap than that of the core crystallite has successfully eliminated the surface traps. Optical absorption and fluorescence emission spectra were used to probe the effect of CdS passivation on the electronic structure of the nanocrystals. The composite CdSe/CdS nanocrystals exhibit strong, narrow(FWHM≤40 nm) and stable band edge photoluminescence. X ray powder diffraction, transmission electron microscopy and X ray photoelectron spectroscopy were used to analyze the composite nanocrystals and determine their average size, size distribution, shape, internal structure and elemental composition.

关键词： CdSe/CdS Nanocrystal Synthesis Characterization

Rutin pretreatment promotes microglial M1 to M2 phenotype polarization

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Neural Regeneration Research 2021年第12期16卷 2499-2504页

作者： guang-Ping Lang Can Li Ying-Ying han Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education Zunyi Medical UniversityZunyiGuizhou ProvinceChina Special Key Laboratory of Oral Diseases Research Higher Education Institutions of Guizhou ProvinceZunyi Medical UniversityZunyiGuizhou ProvinceChina

Microglial cells are important resident innate immune components in the central nervous system that are often activated during *** microglia can display one of two phenotypes,M1 or M2,which each play distinct roles in ***,a dietary flavonoid,exhibits protective effects against ***,whether rutin is able to influence the M1/M2 polarization of microglia remains *** this study,in vitro BV-2 cell models of neuroinflammation were established using 100 ng/mL lipopolysaccharide to investigate the effects of 1-hour rutin pretreatment on microglial *** results revealed that rutin pretreatment reduced the expression of the proinflammatory cytokines tumor necrosis factor-α,interleukin-1β,and interleukin-6 and increased the secretion of *** pretreatment also downregulated the expression of the M1 microglial markers CD86 and inducible nitric oxide synthase and upregulated the expression of the M2 microglial markers arginase 1 and *** pretreatment inhibited the expression of Toll-like receptor 4 and myeloid differentiation factor 88 and blocked the phosphorylation of I kappa B kinase and nuclear factor-kappa *** results showed that rutin pretreatment may promote the phenotypic switch of microglia M1 to M2 by inhibiting the Toll-like receptor 4/nuclear factor-kappa B signaling pathway to alleviate lipopolysaccharide-induced neuroinflammation.

关键词： BV-2 cells flavonoid M1 microglia M2 microglia microglia activation microglia polarization neuroinflammation proinflammatory cytokines rutin TLR-4 signaling

Existence of Mild Solutions for a Class of Fractional Non-autonomous Evolution Equations with Delay

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Acta Mathematicae Applicatae Sinica 2020年第4期36卷 870-878页

作者： Bo ZHU Bao-yan han Wen-guang YU School of Mathematics and Quantitative Economics Shandong University of Finance and EconomicsJinan 250014China Common Course Teaching Department Shandong University of Art and DesignJinan 250014China School of Insurance Shandong University of Finance and EconomicsJinan 250014China

In this paper,we consider the existence and uniqueness of the mild solutions for a class of fractional non-autonomous evolution equations with delay and Caputo's fractional *** using the measure of noncompactness,β-resolvent family,fixed point theorems and Banach contraction mapping principle,we improve and generalizes some related results on this *** last,we give an example to illustrate the application of the main results of this paper.

关键词： Fractional non-autonomous evolution equations β-resolvent family Mild solution Measure of noncompactness.

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以南岸区为例探讨重庆洪旱灾害应对工作

武汉船舶职业技术学院学报 2024年第4期23卷 88-92页

作者：高光淑陈国涵重庆市南岸区河长制工作指导中心重庆401336 重庆市南岸区三峡移民事务中心重庆401336

近些年来,受全球气候变化影响,我国极端洪旱灾害事件时有发生,对区域经济社会发展造成严重影响。以重庆市南岸区为例,分析南岸区洪旱灾害防御问题和应对方法,提出如何进一步搞好洪旱灾害应对工作的建议,以期为当地洪旱灾害防治提供参考。

关键词：南岸区洪旱灾害应对建议

神经外科Ⅰ类切口手术预防使用抗菌药物情况调查及术后颅内感染影响因素分析

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中国处方药 2024年第9期22卷 46-49页

作者：韩广信王昌盛广东药科大学附属第一医院广州510062

目的调查某院神经外科Ⅰ类切口手术预防使用抗菌药物情况及分析术后颅内感染影响因素,为制订某院Ⅰ类切口手术预防使用抗菌药物管理制度,采取临床干预,实施监控措施提供依据。方法抽调2023年1月~5月在某院神经外科接受Ⅰ类切口手术患者... 详细信息

目的调查某院神经外科Ⅰ类切口手术预防使用抗菌药物情况及分析术后颅内感染影响因素,为制订某院Ⅰ类切口手术预防使用抗菌药物管理制度,采取临床干预,实施监控措施提供依据。方法抽调2023年1月~5月在某院神经外科接受Ⅰ类切口手术患者的病例资料,共1276例,按统一方法及标准统计分析某院神经外科Ⅰ类切口手术预防用抗菌药物及术后颅内感染情况。结果1276例患者中,预防性使用抗菌药物的比例为96.6%(1232/1276);抗菌药物品种选择的合理率为51.1%(629/1232);给药时机的合理率为86.8%(1069/1232);术中应追加的合理率为23.4%(97/415);疗程≤24 h的比例为11.8%(145/1232);24 h48 h的比例为86.0%(1060/1232);术后颅内感染发生率为2.1%(27/1276);细菌培养的阳性率为40.7%(11/27);单因素分析结果显示:手术时间>4 h,术中出血量>750 ml,颅内置引流管时间>72 h是术后颅内感染的高危因素。结论某院神经外科Ⅰ类切口手术抗菌药物使用存在预防用药比例高,品种选择合理率低、疗程长、给药时机及术中应追加的合理率低等问题。建议某院根据国家围术期抗菌药物管理规范,对神经外科Ⅰ类切口手术患者进行术后颅内感染风险预测及分层,探索有效、可行的管理模式,提高神经外科Ⅰ类切口手术抗菌药物的合理应用水平。

关键词：神经外科 Ⅰ类切口抗菌药物颅内感染影响因素