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Role of flood discharge in shaping stream geometry:Analysis of a small modern stream in the Uinta Basin,USA

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Journal of Palaeogeography 2017年第1期6卷 84-95页

作者： guang-ming hu Ru-Xin Ding Yan-Bing Li Jing-Fu Shan Xiao-Tao Yu Wei Feng School of Geosciences Yangtze UniversityWuhan 430100HubeiChina State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing 102249China School of Earth Science and Geological Engineering Sun Yat-sen UniversityGuangzhou 510275GuangdongChina guangdong Provincial Key Laboratory of Mineral Resources and Geological Processes Guangzhou 510275GuangdongChina The Third Production Plant Daqing Oilfield BranchPetroChinaDaqing 163000HeilongjiangChina

This small modern river system is located on a retativety flat （about 1°-2°）, unconsotidated sandy pediment surface in the Uinta Basin of Utah, USA, and it is with a scare of about 30 m tong and 0.4-0.8 m wide, simitar as a natural flume experiment modet. The smart stream is informatty divided into upstream, midstream and downstream. The anatysis shows that flood discharge influences channet sinuosity and morphology to produce an initiat meandering pattern which is tater changed to a braided and then a straisht pattern in the downflow direction. The upstream segment has a hish sinuous geometry dominated by both erosion （cutbanks） and deposition （point bars）. In the resistance of sporadic vegetation rooting in banks, the upstream flood deviates its original direction, which resutts in the powerful flood intensively eroding the cutbank and accreting clastics to build point bars, and thus producing a high sinuous channet. The midstream is dominated by deposits （many smart bars） with a moderate to tow sinuosity. Due to the bad drainage of the high sinuous channel in the upstream, the strong flood can cut off the point bar comptetely or even surmount the tevee in the fast meandering upstream, which widens the channel suddenty with a quick decreasing current power. Then, the ctastics from the upstream are untoaded in the midstream and form many smart bars. Untoaded sediments protect the bank, and the tow-power current brings a moderate erosion to the bank, which forms a moderate to tow sinuous channel in the midstream. The downstream shows multistage erosionat terraces in its retativety straight channets. After the midstream water drops its toad, it becomes ＂dear＂ and reaches downstream, the tower current power is hetptess to reform channet 8eometry. Thus, the downstream channel sesment keeps a tower sinuous geometry, evenstraight partially. Small amounts of fine clastics are deposited, and simultaneously multistage terraces are formed due to regressive flood erosion.

关键词： Sinuosity Braiding Point bar Channel bar Flood discharge Uinta Basin

Unraveling brain aging through the lens of oral microbiota

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Neural Regeneration Research 2025年第7期20卷 1930-1943页

作者： Qinchao hu Si Wang Weiqi Zhang Jing Qu guang-hui Liu State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Hospital of Stomatology Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Advanced Innovation Center for human Brain Protection and National Clinical Research Center for Geriatric Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Aging Translational Medicine Center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijingChina CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijingChina University of Chinese Academy of Sciences BeijingChina Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijingChina Aging Biomarker Consortium BeijingChina State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Beijing Institute for Stem Cell and Regenerative Medicine BeijingChina

The oral cavity is a complex physiological community encompassing a wide range of *** of oral microbiota can lead to various oral infectious diseases,such as periodontitis and tooth decay,and even affect systemic health,including brain aging and neurodegenerative *** studies have highlighted how oral microbes might be involved in brain aging and neurodegeneration,indicating potential avenues for intervention *** this review,we summarize clinical evidence demonstrating a link between oral microbes/oral infectious diseases and brain aging/neurodegenerative diseases,and dissect potential mechanisms by which oral microbes contribute to brain aging and *** also highlight advances in therapeutic development grounded in the realm of oral microbes,with the goal of advancing brain health and promoting healthy aging.

关键词： Alzheimer's disease brain aging multiple sclerosis neurodegeneration neurodegenerative diseases oral microbiota Parkinson's disease periodontitis bacteria Porphyromonas gingivalis

Health risks of rare earth elements exposure:Impact on mitochondrial DNA copy number and micronucleus frequency

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Journal of Environmental Sciences 2025年第5期151卷 150-160页

作者： Shiyi Hong Yali Zhang Qiaojian Zhang Zekang Su Guiping hu Li Wang Shanfa Yu Xiaojun Zhu guang Jia Department of Occupational and Environmental Health Sciences School of Public HealthPeking UniversityBeijing 100083China School of Engineering Medicine and Beijing Advanced Innovation Center for Big Data-Based Precision Medicine Beihang UniversityBeijing 100083China Department of Toxicology School of Public HealthBaotou Medical CollegeBaotouInner Mongolia 014040China Henan Institute for Occupational Medicine Zhengzhou 450052China National Center for Occupational Safety and Health Beijing 102308China Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety School of Public HealthPeking UniversityBeijing 100083China

Toxic effects in terms of mitochondria and hereditary substances have been characterized in vitro for individual rare earth elements,while,the joint effects of mixed elements exposure in the population remain *** on the Occupational Chromate Exposure Dynamic Cohort of China,this study investigated the relationship between 15 blood rare earth elements(cerium,dysprosium,erbium,europium,gadolinium,holmium,lanthanum,lutetium,neodymium,praseodymium,samarium,terbium,thulium,yttrium,and ytterbium)and mitochondrial DNA copy number(MtDNACN)as well as peripheral blood lymphocyte micronucleus frequency(MNF).The elastic net was used to select elements highly correlated with effect indicators,whose dose-response relationships were further illustrated by restricted cubic *** kernel regressionwas employed to explore the combined effects of elements and the contributions of single *** results showed that most rare earth elementswere positively correlatedwith effect indicators,with yttrium showing the strongest association(β(95%CI):0.139(0.1089–0.189)for MtDNACN,0.937(0.345–1.684)for MNF).In the mixed exposure model,with the exposure level fixed at the 50th percentile as the reference,the effect estimates on MtDNACN and MNF increased by 0.228 and 0.598 units,respectively,at the 75th *** single effect analysis implied that yttrium,lanthanum and terbium contributed the most to the elevation of MtDNACN,while yttrium posed the highest risk for genetic damage,accordingly,we provided recommendations to prioritize these elements of *** addition,we observed a chief mediating effect of MtDNACN on the elevation of MNF caused by lanthanum,whereas further mechanistic exploration is required to confirm this finding.

关键词： Rare earth elements Mitochondrial DNA copy number Micronucleus frequency Mixed effect

Polymer-based smart fibers and textiles for wearable electronics

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Science China(Technological Sciences) 2025年第1期68卷 81-116页

作者： Sanming hu Li WANG Zaixian YUAN Kun CHEN Wei PENG Hai YIN Zhijun SHI guang YANG School of Biomedical Engineering and Imaging Xianning Medical CollegeHubei University of Science and TechnologyXianning 437100China College of Life Science and Technology Huazhong University of Science and TechnologyWuhan 430074China Wuhan Branch of the National Science Library Chinese Academy of SciencesWuhan 430071China

Smart fibers and textiles have attracted considerable interest for application in wearable devices because of their advantages of being human-friendly,lightweight,flexible,and *** addition,they are considered to have potential applications in health monitoring,energy management,and human-machine interaction *** and polymer fibers,with excellent mechanical strength,wrinkle resistance,and heat resistance,are widely used to fabricate smart fibers and ***,a comprehensive overview of polymer-based fibers and textiles is ***,we review the design principles of various polymer-based smart textiles,including textile-based sensors,energy capture and storage textiles,and computation and display ***,materials used for preparing polymer-based smart fibers,such as metals,carbon-based materials,and natural and synthetic polymers,particularly conductive polymers,are *** addition,this review summarizes key technologies used for preparing smart fibers and the conventional structures of smart ***,the applications of smart textiles in personal health monitoring,thermal management,energy capture and storage,and computation and displays are ***,the current challenges,limitations,and future trends of smart fibers and textiles are discussed.

关键词： polymers smart fibers smart textiles wearable electronics health management

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Bloch函数到BMOA空间的距离

数学学报（中文版） 2022年第4期65卷 723-732页

作者：胡光明刘军明漆毅唐树安金陵科技学院理学院南京211169 广东工业大学应用数学学院广州510520 北京航空航天大学数学科学学院北京100191 贵州师范大学数学科学学院贵阳550001

本文利用高阶导数形式给出了Bloch函数到BMOA空间的距离刻画.这些结论推广了由Peter Jones和赵如汉等人所得到的一阶导数形式的距离公式.作为应用,我们给出了关于小Teichmüller空间的一些等价刻画.

关键词： BMOA空间小Bloch空间小Teichmüller空间

New perspectives on DNA methylation modifications in ocular diseases

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International Journal of Ophthalmology(English edition) 2025年第2期18卷 340-350页

作者： Fei-Fei Zong Da-Dong Jia guang-Kun huang Meng Pan Hao hu Shi-Yi Song Liang Xiao Ru-Weng Wang Liang Liang The First College of Clinical Medical Science China Three Gorges UniversityDepartment of PathologyYichang Central People’s HospitalYichang 443003Hubei ProvinceChina The Second People’s Hospital of China Three Gorges University the Second People’s Hospital of YichangYichang 443000Hubei ProvinceChina Department of Ophthalmology the First Affiliated Hospital of Kunming Medical UniversityKunming 650032Yunnan ProvinceChina Shaanxi University of Chinese Medicine Basic Medical CollegeXianyang 712046Shaanxi ProvinceChina

The methylation of DNA is a prevalent epigenetic modification that plays a crucial role in the pathological progression of ocular *** methylation can regulate gene expression,thereby affecting cell function and signal *** diseases are a kind of complex diseases,and their pathogenesis involves many factors such as genetic,environmental and individual *** addition,inflammation,oxidative stress and lipid metabolism,which abnormal DNA methylation is closely related to,are also considered to be major factors in eye *** current understanding of DNA methylation in eye diseases is becoming more complex and *** addition to the simple suppression of gene expression by hypermethylation,factors such as hypomethylation or demethylation,DNA methylation in non-promoter regions,interactions with other epigenetic modifications,and dynamic changes in DNA methylation must also be ***,although some genes are at abnormal methylation levels,their expression is not significantly changed,which indirectly reflects the complexity of gene *** review aims to summarize and compare some relevant studies,and provide with new ideas and methods for the prevention and treatment of different eye diseases,such as glaucoma,retinoblastoma,and diabetic retinopathy.

关键词： DNA methylation modification epigenetic glaucoma retinoblastoma diabetic retinopathy methylase inhibitors

Near-infrared organic photosensitizers with aggregation-induced emission and switchable fluorescence for fungal infection therapy

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Science China Chemistry 2025年

作者： Xinzhe Yang Zixuan huang Keke Ding huili Yang Lirong Wang Qing Xia Rong hu guang Shi Bingjia Xu Anjun Qin School of Chemistry South China Normal University State Key Laboratory of Luminescent Materials and Devices Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates Center for Aggregation-Induced Emission AIE Institute South China University of Technology Department of Urology The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College) School of Chemistry and Chemical Engineering University of South China

The development of near-infrared (NIR) photosensitizers with aggregation-induced emission (AIE) properties,switchable luminescence colors,and satisfactory photodynamic therapy (PDT) effects on the treatment of fungal infection is of great importance but very ***,two ionic organic luminogens are constructed by employing diphenylamine,diphenylacrylonitrile/1,2-diphenylethene,and methylated quinoline cation as building *** is found that the resulting compounds TCQF and TQF show apparent AIE properties and produce intense fluorescence with high photoluminescence quantum yields of up to 31.2%in the solid *** the meantime,their emission colors can be switched between red and NIR and in the NIR region by mechanical force and solvent vapor,respectively,thereby enabling remarkable and reversible mechanochromism with emission variations of up to 104 *** excitingly,TCQF and TQF can efficiently generate ROS under the illumination of white light and show excellent antimicrobial activities and satisfactory PDT *** by the unique anti-fungus properties,TCQF is employed as a biocompatible NIR photosensitizer for treating wound infection with ***,and apparent PDT effects are *** work provides a new direction for the development of multifunctional NIR materials with AIE properties.

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Precision storage lifetime measurements of highly charged heavy ions in the CSRe storage ring using a Schottky resonator

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Nuclear Science and Techniques 2025年第1期36卷 150-160页

作者： Qian Wang Xin-Liang Yan guang-Yu Zhu Shahab Sanjari Li-Jun Mao He Zhao Yuri ALitvinov Rui-Jiu Chen Meng Wang Yu-hu Zhang You-Jin Yuan Jun-Xia Wu Hong-Yang Jiao Yue Yu Zu-Yi Chen Yin-Fang Luo Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China GSI Helmholtzzentrum für Schwerionenforschung Planckstrasse 164291 DarmstadtGermany FH Aachen University of Applied Sciences Heinrich-Mussmann-Str.152428 JülichGermany

Schottky mass spectrometry utilizing heavy-ion storage rings is a powerful technique for the precise mass and decay half-life measurements of highly charged *** to the nondestructive ion detection features of Schottky noise detectors,the number of stored ions in the ring is determined by the peak area in the measured revolution frequency *** of their intrinsic amplitude-frequency characteristic(AFC),Schottky detector systems exhibit varying sensitivities at different *** low-energy electron-cooled stored ions,a new method is developed to calibrate the AFC curve of the Schottky detector system of the Experimental Cooler Storage Ring(CSRe)storage ring located in Lanzhou,*** the amplitude-calibrated frequency spectrum,a notable refinement was observed in the precision of both the peak position and peak *** a result,the storage lifetimes of the electron-cooled fully ionized^(56)Fe^(26+)ions were determined with high precision at beam energies of 13.7 and 116.4 MeV/u,despite of frequency drifts during the *** electron cooling was turned off,the effective vacuum condition experienced by the 116.4 MeV/u^(56)Fe^(26+)ions was determined using amplitude-calibrated spectra,revealing a value of 2×10^(−10)mbar,which is consistent with vacuum gauge readings along the CSRe *** method reported herein will be adapted for the next-generation storage ring of the HIAF facility under construction in huizhou,*** can also be adapted to other storage ring facilities worldwide to improve precision and enhance lifetime measurements using many ions in the ring.

关键词： Lifetime measurement Schottky mass spectrometry Sensitivity response Highly charged heavy ion Resonator UH vacuum Nondestructive diagnostics

高效液相色谱-抑制化学发光法检测药物中的扑热息痛

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西南师范大学学报（自然科学版） 2003年第3期28卷 500-503页

作者：杨光明周光明胡君梅西南师范大学化学化工学院重庆400715 四川省宣汉县东乡镇东南中心小学四川宣汉636162

基于扑热息痛对鲁米诺铁氰化钾化学发光体系的抑制作用,采用HypersilC18色谱柱分离、抑制化学发光法检测了药物中的扑热息痛含量.扑热息痛浓度在8 0×10-7～1 6×10-5g/mL范围内与化学发光强度呈良好的线性关系,检测限(3σ)为7 4×10-8g... 详细信息

基于扑热息痛对鲁米诺铁氰化钾化学发光体系的抑制作用,采用HypersilC18色谱柱分离、抑制化学发光法检测了药物中的扑热息痛含量.扑热息痛浓度在8 0×10-7～1 6×10-5g/mL范围内与化学发光强度呈良好的线性关系,检测限(3σ)为7 4×10-8g/mL,方法的相对标准偏差为3 4%.该方法已成功应用于扑热息痛片、散利痛和维C银翘片中扑热息痛含量的测定.

关键词：药物检测扑热息痛含量测定高效液相色谱法抑制化学发光法鲁米诺-铁氰化钾化学发光体系