检索结果-南通市图书馆

Effect and Safety of Herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy:A Multicenter Double-Blind Randomized Controlled Trial

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2024年第3期30卷 195-202页

作者： HUANG Hao-yue LIN Yu-ping WEI Hua FU Yu ZHOU yue-hong FANG Zhao-hui QIU Xiao-tang WANG Mei LI Qing-bo LI shan-shan WANG Shi-dong DAI Fang LIU Zhen-jie ZHAO Ling WEN Jian-xuan WU Li-yan ZENG Hui-yan ZHANG Jin-ming LU Qi-yun HE Liu SONG Wei SUN Lu LUO Lu-lu HE Jia-li XIE Wen-wen LIANG Qing-shun HUANG Yuan ZHU Sheng-ling LONG Jie-er GAO Zhi-juan WEN Ze-huai LI Chun-ji OUYANG Wen-wei LI Geng WU Ming-hui LI An-xiang HUANG Jin-zhu Sanjoy K Paul TANG Xian-yu FAN guan-jie Department of Endocrinology Guangdong Provincial Hospital of Chinese MedicineGuangzhou510120China The Second Clinical College of guangzhou University of Chinese Medicine Guangzhou510120China Department of Endocrinology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou510120China guangdong Provincial Academy of Chinese Medical Sciences Guangzhou510120China Department of Endocrinology The First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou450000China Department of Endocrinology Liuyang Hospital of Chinese MedicineChangsha410000China Department of Endocrinology The First Affiliated Hospital of Anhui University of Chinese MedicineHefei230000China Department of Endocrinology Hainan Provincial Hospital of Traditional Chinese MedicineHaikou570100China Department of Endocrinology The Affiliated Hospital of Liaoning University of Traditional Chinese MedicineShenyang110000China Department of Geriatric Luoyang No.1 Hospital of Traditional Chinese MedicineLuoyangHenan Province471000China Department of Endocrinology The Second Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Department of Endocrinology Beijing University of Chinese Medicine Affiliated Dongzhimen HospitalBeijing100000China Department of Endocrinology The First Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Melbourne EpiCentre The University of Melbourne and Melbourne HealthMelbourne3013Australia

Objective:To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled *** with DPN were recruited between November 18,2016 and May 30,2018 from 8 hospitals in *** patients received basic treatments for glycemic *** received foot baths with TW herbal granules either 66.9 g(intervention group)or 6.69 g(control group)for 30 min once a day for 2 weeks and followed by a 2-week rest,as a therapeutic *** the Toronto Clinical Scoring System total score(TCSS-TS)6 points,the patients received a total of 3 therapeutic courses(for 12 weeks)and were followed up for 12 *** primary outcome was change in TCSS-TS score at 12 and 24 *** outcomes included changes in bilateral motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of the median and common peroneal *** was also ***:Totally 632 patients were enrolled,and 317 and 315 were randomized to the intervention and control groups,*** the 12-week intervention,patients in both groups showed significant declines in TCSSTS scores,and significant increases in MNCV and SNCV of the median and common peroneal nerves compared with pre-treatment(P0.05),and no serious adverse event was related with ***:Treatment of TW foot baths was safe and significantly benefitted patients with DPN.A low dose of TW appeared to be more effective than a high dose.(Registry *** CTR-IOR-16009331)

关键词： diabetic peripheral neuropathy herbal medicine foot baths Chinese medicine randomized controlled trial Tangbi Waixi Decoction

在线全文

学校读者我要写书评

暂无评论

四氟菊酯的核磁共振法分析

分析测试学报 2003年第3期22卷 63-65页

作者：祝亚非关山越邵伟艳中山大学测试中心广东广州510275

采用 1HNMR、13CNMR、无畸变增强极化转移实验 (DEPT)、1H - 1H相关谱 (COSY)、1H检测异核多量子相关谱 (HMQC)、1H检测的异核多键相关谱 (HMBC)等方法 ,对四氟菊酯的 1H和 13CNMR谱信号进行了归属 ;并用奥氏核效应 (NOE)差谱法确定了... 详细信息

采用 1HNMR、13CNMR、无畸变增强极化转移实验 (DEPT)、1H - 1H相关谱 (COSY)、1H检测异核多量子相关谱 (HMQC)、1H检测的异核多键相关谱 (HMBC)等方法 ,对四氟菊酯的 1H和 13CNMR谱信号进行了归属 ;并用奥氏核效应 (NOE)差谱法确定了该化合物的立体结构。

关键词：四氟菊酯核磁共振法分析拟除虫菊酯杀虫剂质量控制结构鉴定

闭合回路相干增益原子系统中完美非互易反射光放大

在线全文

学校读者我要写书评

暂无评论

物理学报 2024年第12期73卷 322-329页

作者：李观荣郑怡婷徐琼怡裴笑山耿玥严冬杨红海南师范大学物理与电子工程学院海口571158

高性能非互易光子器件能够有效地提升光量子操控、信息处理以及量子模拟的效率.放大的光信号可以增强并隔离量子系统输出的微弱信号,避免敏感量子系统受反向散射噪声等影响,是高性能光子器件的核心技术.在我们先前的工作(2023 *** 31382... 详细信息

高性能非互易光子器件能够有效地提升光量子操控、信息处理以及量子模拟的效率.放大的光信号可以增强并隔离量子系统输出的微弱信号,避免敏感量子系统受反向散射噪声等影响,是高性能光子器件的核心技术.在我们先前的工作(2023 *** 3138228)中,基于四波混频增益并利用耦合场强度随位置线性变化实现了单向反射光放大的动力学调控.本文巧妙地设计了简单的三能级闭合回路相干增益原子系统,创新性地设置耦合场强度随位置阶梯型变化来破坏极化率空间对称性实现了完美非互易反射光放大.相比之下,耦合场强度阶梯型变化在实验上更容易调节,大大地降低了实验难度.特别地,该系统引入了相位调制.通过改变相位能够切换探测光增益和吸收的频率域,对反射光放大的调节更具灵活性.

关键词：完美非互易反射光放大相对相位

A pilot study of precision treatment for patients with lung cancer pain by Longteng Tongluo recipe(龙藤通络方) using serum genomics

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medicine 2024年第5期44卷 1006-1016页

作者： WU Ruixin FANG Qingliang guan Sisi WEI Xianglong shan Mengjun MAO Zhujun GONG Yabin XU Ling ZHOU Di DONG Changsheng Preclinical Department Shanghai Municipal Hospital of Traditional Chinese MedicineShanghai University of Traditional Chinese Medicine School of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Department of Oncology Longhua HospitalShanghai University of Traditional Chinese Medicine Department of Oncology the Third Affiliated Hospital of Henan University of Traditional Chinese Medicine Department of Oncology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese Medicine Cancer Institute of Traditional Chinese Medicine/Department of Oncology Longhua HospitalShanghai University of Traditional Chinese Medicine

OBJECTIVE: To investigate the efficacy of Longteng Tongluo recipe(龙藤通络方, LTTL) combined with threestep analgesia for the treatment of lung cancer pain, and the changes in serum miRNA expressions before-and after treatment with LTTL and its correlation with lung cancer pain. The possible mechanism underlying LTTL effects on the treatment of lung cancer pain was conducted. METHODS: The pilot study was conducted at the oncology ward of the yueyang Hospital and the Longhua Hospital between March 2018 and October 2019. A prospective, single-blind, placebo controlled, randomized clinical trial of LTTL or placebo combined with three-step analgesia treatments were administered to 24 cancer pain patients diagnosed with lung cancer. Analgesic efficacy was investigated as the primary outcome. Equivalent morphine consumption and numerical rating scale(NRS) scores were used as the secondary outcome. In the present study, we utilized deep sequencing techniques to compare the differential miRNA expressions in serum samples obtained from two groups: the lung cancer pain treatment group(LTTL + three-step analgesia) and the control group(placebo + three-step analgesia). Next, we employed the target prediction database to investigate the target genes for differential miRNA expressions and Gene Ontology(GO) analysis along with Kyoto Encyclopedia of Genes and Genomes(KEGG) pathway enrichment analysis to examine the roles and the major biochemical and signaling pathways related to the differentially expressed target genes, respectively. RESULTS: LTTL treatment significantly reduces the NRS score(P = 0.021) as compared to those before treatment, along with significant reductions in the total morphine equivalent consumption(P = 0.007) and the average daily equivalent morphine consumption(P = 0.003) as opposed to the control group. The expressions of 31 miRNAs differed considerably between the two groups of patients( ≥ 2 times up-modulated or down-regulated between these groups, P < 0.05).

关键词： Longteng Tongluo recipe MicroRNA-chip Supporting information high-throughput nucleotide sequencing lung neoplasms neoplasm metastasis pain

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

螺纹钢锚杆直径与钻孔直径的合理匹配

辽宁工程技术大学学报（自然科学版） 2000年第5期19卷 474-477页

作者：马念杰曹树刚官山月中国矿业大学北京校区北京100083

以大量的实验室和现场试验为基础 ,从技术经济上深入研究了螺纹钢锚杆直径与锚杆外孔直径的合理匹配关系。研究结果认为 ,锚杆钻孔直径为 2 8mm ,使用直径为 2 2mm的无纵筋螺纹钢筋锚杆或直径为 2 0mm带纵筋建筑螺纹钢筋锚杆 ,可以取得... 详细信息

以大量的实验室和现场试验为基础 ,从技术经济上深入研究了螺纹钢锚杆直径与锚杆外孔直径的合理匹配关系。研究结果认为 ,锚杆钻孔直径为 2 8mm ,使用直径为 2 2mm的无纵筋螺纹钢筋锚杆或直径为 2 0mm带纵筋建筑螺纹钢筋锚杆 ,可以取得较大的锚固效果和较好的经济效益。

关键词：锚杆钻孔匹配直径螺纹钢锚杆支护

塔里木盆地西南地区与相邻中亚盆地白垩系——古近系沉积演化对比

在线全文

学校读者我要写书评

暂无评论

沉积与特提斯地质 2017年第3期37卷 103-112页

作者：任泓宇傅恒纪佳关月珊朱达成都理工大学能源学院四川成都610059

塔西南地区位于新特提斯洋北缘,与中亚地区的阿莱盆地、费尔干纳盆地和塔吉克盆地连通。本文综合前人构造研究成果及塔西南地区最新钻井、野外露头资料,发现塔西南地区白垩系—古近系经历了陆相-海相-陆相的沉积演化过程。下白垩统及始... 详细信息

塔西南地区位于新特提斯洋北缘,与中亚地区的阿莱盆地、费尔干纳盆地和塔吉克盆地连通。本文综合前人构造研究成果及塔西南地区最新钻井、野外露头资料,发现塔西南地区白垩系—古近系经历了陆相-海相-陆相的沉积演化过程。下白垩统及始新统上部—渐新统发育陆相沉积,为冲积扇-扇三角洲-湖泊沉积体系;上白垩统—始新统下部发育海相沉积,识别出蒸发台地、开阔台地、局限台地和有障壁海岸等沉积相。中亚地区白垩系—古近系受新特提斯洋海侵-海退过程的影响,整体与塔西南地区同步,也经历了陆相-海相-陆相的沉积演化过程。

关键词：塔西南地区中亚盆地沉积构造演化沉积体系沉积序列对比白垩系古近系

在线全文

学校读者我要写书评

暂无评论

温度对沙巴拟刀角瓢虫生长发育和繁殖的影响

应用昆虫学报 2022年第2期59卷 386-391页

作者：杨果润赵冬梅梁建锋关月姗杨仪韩王兴民广东省生物农药创制与应用重点实验室广东省农业害虫生物防治工程研究中心华南农业大学植物保护学院昆虫学系广州510642 浙江大学山东(临沂)现代农业研究院临沂276034 岭南现代农业科学与技术广东省实验室茂名分中心茂名525099

【目的】明确不同温度对沙巴拟刀角瓢虫Serangiella sababensis生长发育和繁殖的影响,为烟粉虱天敌的应用提供理论依据。【方法】在17、20、25、30和32℃的恒温条件下,测定沙巴拟刀角瓢虫的存活率和发育历期,计算出发育起点温度、有效... 详细信息

【目的】明确不同温度对沙巴拟刀角瓢虫Serangiella sababensis生长发育和繁殖的影响,为烟粉虱天敌的应用提供理论依据。【方法】在17、20、25、30和32℃的恒温条件下,测定沙巴拟刀角瓢虫的存活率和发育历期,计算出发育起点温度、有效积温和生命表参数。【结果】成虫前期存活率和产卵量在25℃时最高,分别为80.78%±6.42%和(284.00±59.71)粒。从卵发育至成虫的发育历期在17℃时最长(57.06±1.28)d,30℃时最短(13.85±0.12)d。成虫前期的发育起点温度和有效积温分别为(11.29±1.86)℃和(271.40±34.44)日·度。在25℃时,沙巴拟刀角瓢虫种群的净增殖力R0最高,内禀增长率rm在30℃最高。【结论】沙巴拟刀角瓢虫的最适温区为25-30℃,与烟粉虱Bemisia tabaci(Gennadius)的最适温区相近,可以在烟粉虱暴发的时期大量应用。

关键词：沙巴拟刀角瓢虫温度发育历期繁殖力生命表烟粉虱

在线全文

学校读者我要写书评

暂无评论

桉树枝瘿姬小蜂胚胎发育及胚后发育

昆虫学报 2022年第7期65卷 905-911页

作者：关月姗朱方丽杨仪韩曹惠怡严玉宁王兴民华南农业大学植物保护学院昆虫系生物防治教育部工程研究中心广州510642 常州市房屋安全和白蚁防治指导中心江苏常州213000 青海高等职业技术学院农业与资源环境系青海海东810700

【目的】对桉属树木的重要害虫桉树枝瘿姬小蜂Leptocybe invasa胚胎发育及胚后发育生物学特征进行详细调查,以期深入了解该害虫的生物学特征及发生为害规律。【方法】对桉树枝瘿姬小蜂雌性生殖系统、卵、虫瘿进行解剖,观察其胚胎发育和... 详细信息

【目的】对桉属树木的重要害虫桉树枝瘿姬小蜂Leptocybe invasa胚胎发育及胚后发育生物学特征进行详细调查,以期深入了解该害虫的生物学特征及发生为害规律。【方法】对桉树枝瘿姬小蜂雌性生殖系统、卵、虫瘿进行解剖,观察其胚胎发育和胚后发育过程,测量其各发育阶段的虫瘿、虫室和幼体的体积及薄壁细胞层的厚度。【结果】桉树枝瘿姬小蜂完成胚胎发育约需138 h,由3个阶段组成:产卵后0-24 h为营养物质聚集期;36-84 h为胚胎期;96-138 h为孵化期。桉树枝瘿姬小蜂在虫瘿内完成发育,其发育过程与虫瘿发育过程保持一致。虫瘿结构由3个基本层组成,由外至内分别为表皮层、中间层和薄壁细胞层。桉树枝瘿姬小蜂幼虫体积增长速率随发育时间呈现单峰型,在30 d时增长速率达到最大;虫瘿体积的增长速率呈抛物线状,并且虫瘿内薄壁细胞层厚度随发育时间也呈现抛物线状,其前期增长较快,后期下降变缓。【结论】桉树枝瘿姬小蜂发育至25 d时处于取食量较小的低龄阶段,而虫瘿内薄壁细胞层(食物)厚度已达到最大,为幼虫体积快速增大阶段作好准备。

关键词：桉树枝瘿姬小蜂胚胎发育胚后发育虫瘿薄壁细胞

在线全文

学校读者我要写书评

暂无评论

乳腺癌术后乳房重建的意义及常用方法

中国医刊 2024年第5期59卷 475-477页

作者：关山首都医科大学附属北京同仁医院乳腺中心北京100176

虽然保乳手术已是早期乳腺癌最主要的手术方式,但对于多中心、病变广泛、术中切缘持续阳性的患者,仍然需要接受乳房切除术治疗。此外,对于家族遗传性乳腺癌或肿瘤与乳房体积比超过保乳整形修复极限的患者,保乳手术可能并非最佳选择。乳... 详细信息

虽然保乳手术已是早期乳腺癌最主要的手术方式,但对于多中心、病变广泛、术中切缘持续阳性的患者,仍然需要接受乳房切除术治疗。此外,对于家族遗传性乳腺癌或肿瘤与乳房体积比超过保乳整形修复极限的患者,保乳手术可能并非最佳选择。乳房切除会给女性患者带来一系列的负面影响,而乳房重建则是弥补乳房缺失根本性的外科治疗手段。

关键词：乳腺癌乳房重建自体组织皮瓣