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The Synthesis of Dialdehyde from Sodium Hydrogen Telluride with 1,1',3,3'-Tetramethyl-2,2'-bis-benzimidazolium Salt

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Chinese Chemical Letters 2002年第9期13卷 836-838页

作者： Yue, Ke Fen gu, huan Shi, Zhen Department of Chemistry Northwest University Xi'an 710069 China

The reaction of bis-benzimidazolium salts with sodium hydrogen telluride is reported, and a new synthetic method for dialdehydes is provided.

关键词： Bis-benzimidazolium salt sodium hydrogen telluride dialdehyde synthesis.

Molecular Mediators of Estrogen Reduction-induced Otolith Shedding

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Current Medical Science 2021年第4期41卷 667-672页

作者： Mei-yan FENG huan-huan gu Qing TIAN Hua-lan YANG Jian-hua ZhuanG Department of Neurology Medical Center for Vertigo and Balance DisordersShanghai Changzheng Hospital of Navy Medical UniversityShanghai200003China Department of Neurology Shanghai Pudong HospitalFudan University Pudong Medical CenterShanghai201399China

Objective Previous study suggested that estradiol(E2)plays an important role in otolith shedding by regulating the expression of otoconin 90(OC90).The purpose of this article is to provide further data on the effect and mechanism of E2 on the morphology of *** The rats receiving bilateral ovariectomy(OVX)were used as animal ***-immunoprecipitation was used to observe the relationship between estrogen receptor(ER)and estrogen-related receptorα(ERRα).The morphology of otolith was observed under the scanning electron *** blotting and qPCR were used for quantitative analysis of the roles of ER and ERRαin regulating OC90 *** The looser otoliths were observed in rats receiving bilateral OVX,which could be reversed by supplementation with *** level of ERRαwas decreased in bilateral OVX *** and ERRαinteracted with each other on the regulation of the expression of *** Our results suggest ER and ERRαare both important downstream receptors involved in regulating OC90 expression in utricles of rats,and ERRαprobably functions by interacting with *** provides evidence for the mechanism of otolith *** it may be significant for future studies of targeted prevention and therapies for benign paroxysmal positional vertigo.

关键词： estrogen-related receptorα estrogen receptor otoconin 90 otolith benign paroxysmal positional vertigo

A case study on behaviors of composite soil nailed wall with bored piles in a deep excavation

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Journal of Central South University 2013年第7期20卷 2017-2024页

作者： ZHU Feng-bin MIAO Lin-chang gu huan-da CHENG Yue-hong Institute of Geotechnical Engineering Southeast University Nanjing 210096 China School of Civil Engineering Suzhou University of Science and Technology Suzhou 215011 China Sttzhou Erjian Construction Group Co. Ltd Suzhou 215131 China

A complete case of a deep excavation was explored. According to the practical working conditions, a 3D non-linear finite element procedure is used to simulate a deep excavation supported by the composite soil nailed wall with bored piles in soft soil. The modified cam clay model is employed as the constitutive relationship of the soil in the numerical simulation. Results from the numerical analysis are fitted well with the field data, which indicate that the research approach used is reliable. Based on the field data and numerical results of the deep excavation supported by four different patterns of the composite soil nailed wall, the significant corner effect is founded in the 3D deep excavation. If bored piles or soil anchors are considered in the composite soil nailed wall, they are beneficial to decreasing deformations and internal forces of bored piles, cement mixing piles, soil anchors, soil nailings and soil around the deep excavation. Besides, the effects due to bored piles are more significant than those deduced from soil anchors. All mentioned above prove that the composite soil nailed wall with bored piles is feasible in the deep excavation.

关键词： deep excavation 3D non-linear finite element bored pile composite soil nailed wall corner effect deformation internal force

A novel method for the formylation of Grignard reagent

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Science China Chemistry 2005年第Z1期48卷 25-28页

作者： SHI Zhen WANG Luyao gu huan LI Jianli BAI Yinjuan YANG Bingqin Department of Chemistry Northwest University Xi'an 710069 China Department of Chemistry Northwest University Xi'an 710069 China Department of Chemistry Northwest University Xi'an 710069 China Department of Chemistry Northwest University Xi'an 710069 China Department of Chemistry Northwest University Xi'an 710069 China Department of Chemistry Northwest University Xi'an 710069 China

A facile and efficient method for the formylation of Grignard reagent was reported, and a new approach for the preparation of aldehydes from Grignard reagent and benzimidazolium salts was provided.

关键词： benzimidazolium salts, Grignard reagent, formylation, aldehyde, synthesis.

DURATION OF APPEARANCE OF Vi ANTIGEN AND SALMONELLA TYPHI IN BLOOD AND URINE OF INFECTED MODELS

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中华医学杂志(英文版) 1991年第1期104卷 46-48页

作者： Wang Dai-ming gu Xin-huan Children's Hospital Shanghai Medical University Shanghai 200032

Salmonella typhi (S typhi) infected models were established to evaluate the latex agglutination test (LAT) and staphylococcal coagglutination test (SCT) for the detection of S typhi Vi antigen in blood and urine. Antigens in serum or urine were detected within 7 days after infection with positive cultures, and decreased in 2 weeks. LAT and SCT were positive in 7 mice with no bacteria isolation from blood and urine but their spleen aspirates yielded S typhi. Both tests are rapid and sensitive and may be used for the diagnosis of typhoid infection, especially in partially treated patients when their blood cultures are negative.

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Osteopontin expression is associated with hepatopathologic changes in Schistosoma japonicum infected mice

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World Journal of Gastroenterology 2011年第46期17卷 5075-5082页

作者： Bo-Lin Chen gui-Ying Zhang Wei-Jian Yuan Shi-Ping Wang Yue-Ming Shen LU Yan huan gu Jia Li Department of Gastroenterology Xiangya Hospital Central South University Changsha 410008 Hunan Province China Department of Pathogenic Biology College of Xiangya Basic Medicine Central South University Changsha 410008 Hunan Province China Department of Gastroenterology Changsha Central Hospital Changsha 410004 Hunan Province China

AIM:To investigate osteopontin expression and its association with hepatopathologic changes in BALB/C mice infected with Schistosoma ***:The schistosomal hepatopathologic mouse model was established by abdominal infection with schistosomal *** samples were obtained from mice sacrif iced at 6,8,10,14,and 18 wk after *** histopathological changes were observed with hematoxylin-eosin and Masson trichrome *** expression of osteopontin was determined with im-munohistochemistry,reverse transcription-polymerase chain reaction,and Western *** expressionof α-smooth muscle actin(α-SMA)and transforming growth factor-β1(TGF-β1)were determined by *** of osteopontin ex-pression with other variables(α-SMA,TGF-β1,hepato-pathologic features including granuloma formation and degree of liver f ibrosis)were ***:Typical schistosomal hepatopathologic changes were induced in the *** changes in the expression of osteopontin were observed at week *** expression increased,peaked at week 10(P<0.01),and then gradually *** correla-tions between osteopontin expression and α-SMA(r=0.720,P<0.01),TGF-β1(r=0.905,P <0.01),granu-loma formation(r=0.875,P<0.01),and degree of liver f ibrosis(r=0.858,P<0.01)were also ***:Osteopontin may play an important role in schistosomal hepatopathology and may promote granuloma formation and liver fi brosis through an un-explored mechanism.

关键词： Schistosoma japonicum, Granuloma Liverfibrosis Osteopontin BALB/C mice

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混合塑料发泡颗粒轻质土的强度特性评价方法

中国公路学报 2007年第1期20卷 41-46页

作者：顾欢达顾熙苏州科技学院土木工程系江苏苏州215011

针对混合塑料发泡颗粒轻质土的特性,利用两相体模型提出了对其强度及变形等工程性质进行评价的方法;并运用该方法,在考虑构成轻质土两种不同材料性质的基础上,对轻质土的强度与变形特性进行了分析。结果表明:该方法可以比较合理地对塑... 详细信息

针对混合塑料发泡颗粒轻质土的特性,利用两相体模型提出了对其强度及变形等工程性质进行评价的方法;并运用该方法,在考虑构成轻质土两种不同材料性质的基础上,对轻质土的强度与变形特性进行了分析。结果表明:该方法可以比较合理地对塑料发泡颗粒轻质土的应力-应变特征及强度特性进行评价;轻质土强度随轻质填充料体积分数的增大而减小,随龄期的增长而提高。

关键词：道路工程塑料发泡颗粒轻质土两相体模型强度特性评价方法

两相体模型在评价发泡颗粒轻质土应力-应变特性中的应用

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岩土工程学报 2006年第8期28卷 994-997页

作者：顾欢达顾熙苏州科技学院土木工程系江苏苏州215011

发泡颗粒轻质土是由基材及轻质填充料两种性质不同的材料构成的两相体材料。利用两相体模型建立发泡颗粒轻质土的应力–应变关系,对不同配比轻质土的应力–应变特性进行评价,并利用试验结果对模型的合理性进行验证,为轻质土的工程应用... 详细信息

发泡颗粒轻质土是由基材及轻质填充料两种性质不同的材料构成的两相体材料。利用两相体模型建立发泡颗粒轻质土的应力–应变关系,对不同配比轻质土的应力–应变特性进行评价,并利用试验结果对模型的合理性进行验证,为轻质土的工程应用提供必要的理论依据。

关键词：轻质土两相体模型体积比应力-应变

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发泡塑料颗粒轻质土的强度、变形特性研究

岩土力学 2006年第11期27卷 1922-1926页

作者：顾欢达顾熙苏州科技学院土木工程系苏州215011

发泡颗粒轻质土是一种比较新颖的土工材料,具有质量轻、强度高等特点。在道路、桥梁、建筑等领域有着广泛的应用前景。为了探讨轻质土的工程特性,利用室内试验及理论分析的方法对发泡颗粒轻质土的强度、变形特性以及影响因素进行了分析... 详细信息

发泡颗粒轻质土是一种比较新颖的土工材料,具有质量轻、强度高等特点。在道路、桥梁、建筑等领域有着广泛的应用前景。为了探讨轻质土的工程特性,利用室内试验及理论分析的方法对发泡颗粒轻质土的强度、变形特性以及影响因素进行了分析。根据分析探讨的结果,利用轻质土的构成特征所建立的两相体计算模型可以比较合理、可靠地分析轻质土的应力-应变特性,并在此基础上可方便地应用计算模型分析时间、轻质填充料含有率等因素对轻质土的强度、变形特性的影响,为轻质土的工程应用提供必要的理论依据。

关键词：轻质土体积比强度两相体模型