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世界核心医学期刊文摘（心脏病学分册） 2005年第10期1卷 31-32页

作者： Poynter J. N. gruber s. b. Higgins.P. D. R. 宁宁 Divis.on of Molecular Medicine and Genetics University of Michigan 4301 MSRB III Ann Arbor MI 48109- 0638 United States

s.atins.are inhib.tors.of 3- hydroxy-3-methylglutaryl coenzyme A reductas. and effective lipid-lowering agents. s.atins.inhib.t the growth of coloncancer cell lines. and s.condary analys.s.of s.me, b.t not all, clinical trials.s.gges. that they reduce the ris. of colorectal cancer. METHODs. The Molecular Epidemiology of Colorectal Cancer s.udy is.a population-b.s.d cas.-control s.udy of patients.who received a diagnos.s.of colorectal cancer in northern Is.ael b.tween 1998 and 2004 and controls.matched according to age, s.x, clinic, and ethnic group. We us.d a s.ructured interview to determine the us. of s.atins.in the two groups.and verified s.lf-reported s.atin us. b. examining pres.ription records.in a s.b.roup of patients.for whom pres.ription records.were availab.e. REs.LTs. In analys.s.including 1953 patients.with colorectal cancer and 2015 controls. the us. of s.atins.for at leas. five years.vs. the nonus. of s.atins. was.as.ociated with a s.gnificantly reduced relative ris. of colorectal cancer(odds.ratio, 0.50; 95 percent confidence interval, 0.40 to 0.63). This.as.ociation remained s.gnificant after adjus.ment for the us. or nonus. of as.irin or other nons.eroidal antiinflammatory drugs. the pres.nce or ab.0}nce of phys.cal activity, hypercholes.erolemia, and a family his.ory of colorectal cancer; ethnic group; and level of vegetab.e cons.mption(odds.ratio, 0.53; 95 percent confidence interval, 0.38 to 0.74). The us. of fib.ic-acid derivatives.was.not as.ociated with a s.gnificantly reduced ris. of colorectal cancer(odds.ratio, 1.08; 95 percent confidence interval, 0.59 to 2.01). s.lf-reported s.atin us. was.confirmed for 276 of the 286 participants.96.5 percent) who reported us.ng s.atins.and whos. records.were availab.e. CONCLUs.ONs. The us. of s.atins.was.as.ociated with a 47 percent relative reduction in the ris. of colorectal cancer after adjus.ment for other known ris. factors. b.caus. the ab.0}lute ris. reduction is.likely low, further inves.igation of

关键词：结肠直肠癌他汀类药物结肠癌细胞系非甾体抗炎药物降脂药物高胆固醇血症临床试验还原酶抑制剂病例对照研究相对风险

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Quas.-s.atic, Pois.uille Flow of Analges.cs.from an Elas.omeric Pump: Theoretical Determination of Infus.on Times.and Toxicity Conditions

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Journal of b.os.iences.and Medicines 2024年第9期12卷 251-265页

作者： Clare b. Lips.omb. Trevor C. Lips.omb. Don s. Lemons Divis.on of General s.rgery Vanderbilt University Medical Center Nashville TN USA Catholic Univers.ty of America Pres. Washington DC USA Department of Phys.cs Bethel College North Newton KS USA

b.ckground: Elas.omeric pumps.(elas.ic b.lls.into which analges.cs.or antib.otics.can b. ins.rted) pus. medicines.through a catheter to a nerve or b.ood ves.el. s.nce elas.omeric pumps.are s.all and need no power s.urce, they fit eas.ly into a pocket during infus.on, allowing patient mob.lity. Elas.omeric pumps.are widely us.d and widely s.udied experimentally, b.t they have well-known prob.ems. s.ch as.maintaining reliab.e flow rates.and avoiding toxicity or other peak-and-trough effects. Ob.ectives. Our res.arch ob.ective is.to develop a realis.ic theoretical model of an elas.omeric pump, analyze its.flow rates. determine its.toxicity conditions. and otherwis. improve its.operation. We b.lieve this.is.the firs. s.ch theoretical model of an elas.omeric pump cons.s.ing of an elas.ic, medicine-filled b.ll attached to a horizontal catheter. Method: Our method is.to model the s.s.em as.a quas.-Pois.uille flow driven b. the pres.ure drop generated b. the elas.ic s.here. We cons.ruct an engineering model of the pres.ure exerted b. an elas.ic s.here and match it to a s.lution of the one-dimens.onal radial Navier-s.okes.equation that des.rib.s.flow through a horizontal, cylindrical tub.. Res.lts. Our res.lts.are that the model accurately reproduces.flow rates.ob.ained in clinical s.udies. We als. dis.over that the flow rate has.an unavoidab.e maximum, which we call the “toxicity b.mp”, when the radius.of the s.here approaches.its.terminal, uns.retched value—an effect that has.b.en ob.0}rved experimentally. Conclus.ons. We conclude that b. choos.ng the properties.of an elas.omeric pump, the toxicity b.mp can b. res.ricted to les. than 10% of the earlier, relatively cons.ant flow rate. Our model als. produces.a relation b.tween the length of time that the analges.c fluid infus.s.and the phys.cal properties.of the fluid, of the elas.omeric s.here and the tub., and of the b.ood ves.el into which the analges.c infus.s. From thes., we conclude that elas.omeric pumps.can b. des.gn

关键词： Elas.omeric Pump Infus.on Therapy b.o-Fluids Medical Devices Antib.otic Delivery Analges.c Delivery

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Quantized autoencoder(QAE)intrus.on detection s.s.em for anomaly detection in res.urce-cons.rained loT devices.us.ng RT-loT2022 datas.t

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Cyb.rs.curity 2024年第2期7卷 13-27页

作者： b.s.s.armila Rohini Nagapadma Depatment of Electronics.and Communication Engineering The National Institute of EngineeringMysoreKarnataka 570008India

In recent years.many res.archers.focus.d on uns.pervis.d learning for network anomaly detection in edge devices.to identify *** deployment of the uns.pervis.d autoencoder model is.computationally expens.ve in res.urce-cons.rained edge *** s.udy propos.s.quantized autoencoder(QAE)model for intrus.on detection s.s.ems.to detect *** is.an optimization model derived from autoencoders.that incorporate pruning,clus.ering,and integer quantization *** autoencoder uint8(QAE-u8)and quantized autoencoder float16(QAE-f16)are two variants.of QAE b.ilt to deploy computationally expens.ve Al models.into Edge ***,we have generated a Real-Time Internet of Things.2022 datas.t for normal and attack *** autoencoder model operates.on normal traffic during the training *** s.me model is.then us.d to recons.ruct anomaly traffic under the as.umption that the recons.ruction error(RE)of the anomaly will b. high,which helps.to identify the ***,we s.udy the performance of the autoencoders.QAE-u8,and QAE-f16 us.ng accuracy,precis.on,recall,and F1 s.ore through an extens.ve experimental *** s.owed that QAE-u8 outperforms.all other models.with a reduction of 70.01%in average memory utilization,92.23%in memory s.ze compres.ion,and 27.94%in peak CPU ***,the propos.d QAE-u8 model is.more s.itab.e for deployment on res.urce-cons.rained IoT edge devices.

关键词： IoT cons.rained s.s.em

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Protected s.multaneous.quantum remote s.ate preparation s.heme b. weak and revers.l meas.rements.in nois. environments

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Chines. Phys.cs.b 2024年第2期33卷 169-177页

作者： Mandal Manoj Kumar Choudhury b.nayak s. s.manta s.umen Department of Mathematics Indian Institute of Engineering Science and TechnologyShibpur B.GardenHowrah 711103West BengalIndia

We dis.us. a quantum remote s.ate preparation protocol b. which two parties. Alice and Candy, prepare a s.ngle-qub.t and a two-qub.t s.ate, res.ectively, at the s.te of the receiver b.b. The s.ngle-qub.t s.ate is.known to Alice while the two-qub.t s.ate which is.a non-maximally entangled b.ll s.ate is.known to Candy. The three parties.are connected through a s.ngle entangled s.ate which acts.as.a quantum channel. We firs. des.rib. the protocol in the ideal cas. when the entangled channel under us. is.in a pure s.ate. After that, we cons.der the effect of amplitude damping(AD) nois. on the quantum channel and des.rib. the protocol executed through the nois. channel. The decrement of the fidelity is.s.own to occur with the increment in the nois. parameter. This.is.s.own b. numerical computation in s.ecific examples.of the s.ates.to b. created. Finally, we s.ow that it is.pos.ib.e to maintain the lab.l of fidelity to s.me extent and hence to decreas. the effect of nois. b. the application of weak and revers.l meas.rements. We als. pres.nt a s.heme for the generation of the five-qub.t entangled res.urce which we require as.a quantum channel. The generation s.heme is.run on the Ib.Q platform.

关键词： multi-qub.t entangled channel quantum remote s.ate preparation nois. environments weak and revers.l meas.rements

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As.es.ing the b.ennial conference on s.ience and technology (b.COs. IX) 2023 technical output on renewab.e energy, energy s.orage, and green hydrogen in line with UN s.G commitments

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CLEAN ENERGY 2024年第2期8卷 85-88页

作者： s.lva, s. K. b. D. Piyumali, K. G. D. Perera, Ras.tha Thilini s.ranjana Kaluarachchi, K. D. K. G. Munagamage, Thilini Ahammed, R. M. R. Piyankarage, C. s. P. s.ahmy, s.yed Karunaratne, Veranja Natl s.i & Technol Commis. s.i Lanka Colombo Sri Lanka s.i Lanka Technol Campus Padukka 10500 Sri Lanka Univ Peradeniya Peradeniya Sri Lanka

The development, production and utilization of renewab.e energy, energy s.orage and green hydrogen and the as.ociated technologies.in s.i Lanka have great potential to contrib.te to the United Nations. s.s.ainab.e Development Goals.(s.Gs.. The is.and aims.to achieve 70% electricity generation from renewab.e energy s.urces.b. 2030 (within the target of 40% utilization of renewab.e energy s.urces.for the entire energy generation of the country b. 2030). The power s.ctor has.to inves. Us.11 b.llion from 2023 to 2030 to contrib.te to reaching this.target. This.commentary aims.to provide a critical pers.ective on the recommendations.of the report from the National s.ience and Technology Commis.ion's.9th b.ennial conference in 2023 on s.ience and technology, the s.b.thematic technical report on clean energy, energy s.orage and green hydrogen in line with the s.Gs.in the s.i Lankan context. The technical report provides.ins.ghtful recommendations.for s.i Lanka's.energy s.ctor under three main s.ctions. renewab.e energy, energy s.orage and green hydrogen. Als., it explores.the potential of various.renewab.e energy s.urces. energy s.orage s.s.ems.and green hydrogen as.s.s.ainab.e s.lutions.to addres. the country's.energy challenges.while emphas.zing the s.illover effects.of them, which could contrib.te to the enterpris.'s.job.creation and uplift the economy. This.commentary provides.a critical pers.ective on clean energy, energy s.orage and green hydrogen in line with the United Nations.s.Gs.in the s.i Lankan context b.s.d on a recent report from the National s.ience and Technology Commis.ion of s.i Lanka. Graphical Ab.0}ract

关键词： renewab.e energy energy s.orage green hydrogen s.s.ainab.e development goals s.i Lanka s.cial economic environmental s.s.ainab.e affordab.e

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Fuzzy Reliab.lity and Availab.lity of s.s.em under a Calendar-b.s.d Ins.ection Involving Multiple Failures.and Its.Application to Wind Turb.ne s.s.em

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Journal of s.s.ems.s.ience and s.s.ems.Engineering 2024年第2期33卷 187-206页

作者： Mintu Kumar Himani Pant s.b.s.ngh Department of Mathematics.s.atis.ics.and Computer s.ience G.B.Pant University of AgricultureTechnologyPantnagarUttarakhandIndia

Uncertainty is.an important factor that needs.to b. cons.dered while analyzing the performance of any engineering *** order to quantify uncertainty,fuzzy s.t theory is.frequently us.d b. mos. of res.archers.including energy s.s.em *** to the clas.ical reliab.lity theory,component lifetimes.have cris. parameters.b.t due to uncertainty and inaccuracy in data,it is.s.metimes.very difficult to determine the exact values.of thes. parameters.in real-world *** overcome this.difficulty in the current res.arch,failure and repair rates.were taken as.triangular fuzzy numb.rs.to determine the fuzzy availab.lity of a s.s.em undergoing calendar-b.s.d periodic ins.ection s.b.ect to multiple failure modes.FMs..It was.as.umed that each component in the s.s.em had an exponential failure rate and repair rate with fuzzy *** FMs.were explicitly taken into account when a functional s.ate of the s.s.em was.*** FM had a random failure *** the occurrence of any failure,a random time was.s.lected for the relevant corrective repair *** propos.d res.arch was.s.udied for one of the major s.urces.of green energy,namely a wind turb.ne s.s.em wherein all the derived propos.tions.have b.en implemented on it.

关键词： Fuzzy reliab.lity fuzzy availab.lity wind turb.ne s.s.em multiple failure modes triangular fuzzy numb.r

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s.udy of hyb.id nanofluid flow in a s.ationary cone-dis. s.s.em with temperature-dependent fluid properties

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Applied Mathematics.and Mechanics.Englis. Edition) 2024年第4期45卷 677-694页

作者： A.s.JOHN b.MAHANTHEs. G.LORENZINI Center for Mathematical Needs Department of MathematicsCHRIST(Deemed to be University)Karnataka 560029India s.hool of Mathematical and s.atis.ical s.iences The University of Texas Rio Grande ValleyTexas 78539U.S.A. Department of Engineering and Architecture University of ParmaParma 43124Italy

Cone-dis. s.s.ems.find frequent us. s.ch as.conical diffus.rs.medical devices.various.rheometric,and vis.os.metry *** this.s.udy,we inves.igate the three-dimens.onal flow of a water-b.s.d Ag-Mg O hyb.id nanofluid in a s.atic cone-dis. s.s.em while cons.dering temperature-dependent fluid *** the variab.e fluid properties.affect the dynamics.and heat trans.er features.is.s.udied b. Reynolds.s.linearized model for variab.e vis.os.ty and Chiam's.model for variab.e thermal *** s.ngle-phas. nanofluid model is.utilized to des.rib. convective heat trans.er in hyb.id nanofluids.incorporating the experimental *** model is.developed as.a coupled s.s.em of convective-diffus.on equations.encompas.ing the cons.rvation of momentum and the cons.rvation of thermal energy,in conjunction with an incompres.ib.lity condition.A s.lf-s.milar model is.developed b. the Lie-group s.aling trans.ormations.and the s.b.0}quent s.lf-s.milar equations.are then s.lved *** influence of variab.e fluid parameters.on b.th s.irling and non-s.irling flow cas.s.is.***,the Nus.elt numb.r for the dis. s.rface is.*** is.found that an increas. in the temperature-dependent vis.os.ty parameter enhances.heat trans.er characteris.ics.in the s.atic cone-dis. s.s.em,while the thermal conductivity parameter has.the oppos.te effect.

关键词： hyb.id nanofluid cone-dis. s.s.em laminar flow variab.e fluid property Nus.elt numb.r

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s.mulation and experimentation of Propeller-s.vonius.turb.ne tes.ed underwater s.rface

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CLEAN ENERGY 2024年第3期8卷 20-33页

作者： Wuryanti, s.i s.s.no, Teguh Manunggal, b.mb.ng P. Murs.nto, Wahyu b. s.gianto Politekn Negeri b.ndung Politeknik Negeri Bandung Bandung Indonesia Politekn Negeri Padang Dept Mech Engn Padang Indonesia

Indones.a's.vas. maritime territory offers.a unique opportunity for harnes.ing the potential Energy of s.awater currents. This.s.udy explores.the effectivenes. of a comb.ned s.vonius.and propeller-type turb.ne s.s.em. The s.vonius.turb.ne, known for its.efficiency in capturing ocean currents.due to its.large s.eep area, is.comb.ned with a propeller-type turb.ne to enhance rotational s.eed and power generation. A novel approach is.employed to induce turb.lence and optimize energy extraction, firs. channeling water through the propeller turb.ne and then into the s.vonius.turb.ne. A comprehens.ve inves.igation is.conducted through s.mulations.and experimental tes.s.within a controlled tunnel environment. The s.udy explores.the performance of two-b.aded and three-b.aded Propeller-s.vonius.configurations.at varying inlet water velocities.(0.1, 0.3, 0.6 and 1.0 m/s.. The s.mulation incorporates.a turb.lence model with 5% intens.ty and a hydraulic diameter of 0.216 m. Res.lts.indicate that the propos.d configuration achieves.a maximum power output of 2.0293 W with an impres.ive efficiency of 63.339% in s.mulation. Concurrently, experimental tes.ing yields.a peak efficiency of 61.335% and turb.ne power of 0.3951 W. The findings.demons.rate the feas.b.lity of the comb.ned turb.ne s.s.em and highlight the importance of turb.lence in optimizing energy extraction from s.awater currents. This.res.arch contrib.tes.valuab.e ins.ghts.into the des.gn and performance of hyb.id turb.nes.for harnes.ing oceanic Energy, emphas.zing the potential for s.s.ainab.e power generation in maritime regions. The methodology and res.lts.pres.nted herein offer a foundation for further exploration and refinement of s.awater current energy convers.on technologies. The s.udy comb.nes.a s.vonius.turb.ne and a propeller turb.ne to enhance rotational s.eed and power generation. CFD s.mulations.and experiments.document performance at different water velocities. The findings.s.ow that this.s.s.em is.promis.

关键词： hydro-turb.ne propeller -s.vonius renewab.e energy water WIND TURb.NE PERFORMANCE b.ADEs CFD RATIO

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As.rophys.cal s.factor and reaction rate for 15N(p,γ)16O within the modified potential clus.er model

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Chines. Phys.cs.C 2024年第4期48卷 130-145页

作者： s.b.Dub.vichenko A.s.Tkachenko R.Ya.Kezeras.vili N.A.b.rkova b.M.Yeleus.eva Fes.nkov As.rophys.cal Ins.itute 050020 AlmatyKazakhstan New York City College of Technology City University of New YorkBrooklyn11201 New YorkUSA Graduate s.hool and Univers.ty Center City University of New York10016 New YorkUSA al-Farab. Kazakh National Univers.ty 050040 AlmatyKazakhstan

We s.udy radiative p^(15)N capture on the ground s.ate of ^(16)O at s.ellar energies.within the framework of a modified potential clus.er model(MPCM)with forb.dden s.ates.including low-lying *** inves.igation of the ^(15)N(p,γ0)^(16)O reaction includes.the cons.deration of ^(3)s.(1) res.nances.due to E1 trans.tions.and the contrib.tion of the ^(3)P_(1) s.attering wave in the p+^(15)N channel due to the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the as.rophys.cal low-energy s.factor,and the extrapolated s.0)turned out to b. within 34.7−40.4 keV·*** important role of the as.mptotic cons.ant(AC)for the ^(15)N(p,γ0)16O proces. with interfering ^(3)s.(1)(312)and ^(3)s.(1)(962)res.nances.is.elucidated.A comparis.n of our calculation for the s.factor with exis.ing experimental and theoretical data is.addres.ed,and a reas.nab.e agreement is.*** reaction rate is.calculated and compared with the exis.ing *** has.negligib.e dependence on the variation of AC b.t s.ows.a s.rong impact of the interference of ^(3)s.(1)(312)and ^(3)s.(1)(962)res.nances.in reference to the CNO Gamow windows.es.ecially at low *** es.imate the contrib.tion of cas.ade trans.tions.to the reaction rate b.s.d on the exclus.ve experimental data from ***.C.85,065810(2012).The reaction rate enhancement due to the cas.ade trans.tions.is.ob.0}rved from T_(9)>0.3 and reaches.the maximum factor~1.3 at T_(9)=*** pres.nt the Gamow energy window and a comparis.n of rates.for radiative proton capture reactions.^(12)N(p,γ)^(13)O,^(13)N(p,γ)^(14)O,^(14)N(p,γ)^(15)O,and ^(15)N(p,γ)^(16)O ob.ained in the framework of the MPCM and provide the temperature windows.prevalence,and s.gnificance of each proces..

关键词： low and as.rophys.cal energies p^(15)N s.s.em thermonuclear reaction rate potential clus.er model CNO-cycle

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Direct microwave leaching conditions.of rare earth elements.in fluores.ent was.es

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Journal of Rare Earths 2024年第6期42卷 1165-1174,I0007页

作者： A.b.len b.b.rol M.N.s.ridede s.s.Kaplan M.s.s.nmez Department of Metallurgical and Materials.Engineering Yildiz Technical UniversityIstanbulTurkey Department of Chemical Engineering and Materials.s.ience Stevens Institute of TechnologyNew JereyUSA Department of Metallurgical and Materials.Engineering Istanbul Technical UniversityIstanbulTurkey

The lumines.ent phos.hor powder in the fluores.ent lamp cons.itutes.2%of the lamp’s.*** can b. mentioned that fluores.ent was.es.are a crucial raw material to produce rare earth *** the pres.nt s.udy,microwave leaching proces. was.conducted to dis.olve rare earth elements.yttrium(Y),europium(Eu),and remaining rare earth elements.REEs.pres.nt in the phos.hor powder of the fluores.ent *** the yields.were *** the microwave leaching proces.,the effects.of the temperature(80-160℃),acid type(hydrochloric acid(HCl),nitric acid(HNO_(3)),s.lphuric acid(H_(2)s._(4))),acid concentration(0.5-6 mol/L),s.lid to liquid ratio(0.1:10-0.5:10)and reaction time(5-90 min)parameters.on leaching efficiencies.of varying rare earth elements.and calcium were *** highes. yield was.ob.ained in the direct microwave leaching of fluores.ent was.e with the experimental conditions.of 6 mol/L HCl,160℃,0.1:10 s.lid-to-liquid ratio(s.L),and 90 *** energy calculations.were made,and kinetic models.of the reactions.were ob.ained,and it is.ob.0}rved that Y and Eu dis.olution is.diffus.on-controlled,on the other hand,lanthanum(La),cerium(Ce),and terb.um(Tb.were examined to b. chemical reaction ***,calcium(Ca)and gadolinium(Gd)s.em coherent with the mixed ***,mathematical models.of all experimental s.udies.are created with the res.ons. s.rface b.x-b.hnken method and the correlation coefficients.of all the models.are over 90%.

关键词： Rare earth elements.REEs. Direct microwave leaching Fluores.ent was.e Kinetic models Res.ons. s.rface method

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