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辣椒杂志 2014年第2期12卷 40-50页

作者： seungill Kim Minkyu Park seon-In Yeom Yong-Min Kim Je Min Lee Hyun-Ah Lee Eunyoung seo Jaeyoung Choi Kyeongchae Cheong Ki-Tae Kim Kyongyong Jung Gir-Won Lee sang-Keun Oh Chungyun Bae saet-Byul Kim Hye-Young Lee shin-Young Kim Myung-shin Kim Byoung-Cheorl Kang Yeong Deuk jo Hee-Bum Yang Hee-Jin Jeong Won-Hee Kang Jin-Kyung Kwon Chanseok shin Jae Yun Lim June Hyun Park Jin Hoe Huh June-sik Kim Byung-Dong Kim Oded Cohen Ilan Paran Mi Chung suh saet Buyl Lee Yeon-Ki Kim Younhee shin seung-Jae Noh Junhyung Park Young sam seo suk-Yoon Kwon Hyun A Kim Jeong Mee Park Hyun-Jin Kim sang-Bong Choi Paul W Bosland gregory reeves.s.ng-hwan jo Bong-Woo Lee Hyung-Taeg Cho Hee-seung Choi Min-soo Lee Yeisoo Yu Yang Do Choi Beom-seok Park Allen van Deynze Hamid Ashrafi Theresa Hill Woo Taek Kim Hyun-sook Pai Hee Kyung Ahn Inhwa Yeam James J Giovannoni jocelyn K C Rose Iben sφrensen sang-Jik Lee Ryan W Kim Ik-Young Choi Beom-soon Choi jong-sung Lim Yong-hwan Lee Doil Choi 刘峰张西露 Department of Plant science seoul National University Plant Genomics and Breeding Institute Seoul National University Department of Agricultural Biotechnology Seoul National University Department of Bioinformatics and Life science Soongsil University Vegetable Breeding Research Center Seoul National University Agricultural Research Organization Institute of Plant Science Volcani Center Bet DaganIsrael. Agricultural Research Organization Institute of Plant Science Volcani Center Bet DaganIsrael Department of Bioenergy science and Technology Chonnam National University Genomics Genetics Institute GreenGene BioTech Inc. Codes Division Insilicogen Inc. Ginseng Resources Research Laboratory Korea Ginseng Corporation Korea Research Institute of Bioscience and Biotechnology Division of Bioscience and Bioinformatics Myongji University Department of Plant and Environmental sciences New Mexico State University Chile Pepper Institute New Mexico State University seeders Inc. Department of Biological sciences Seoul National University Arizona Genomics Institute University of Arizona Agricultural Genome Center National Academy of Agricultural Science Rural Development Administration seed Biotechnology Center University of California Davis Davis California USA Department of systems Biology Yonsei University Department of Horticulture and Breeding Andong National University Us Department of Agriculture-Agricultural Research service Robert W. Holley Center Ithaca New York USA Boyce Thompson Institute for Plant Research Cornell University Ithaca New York USA Department of Plant Biology Cornell University Ithaca New York USA Biotechnology Institute Nongwoo Bio Yeoju Korea Genome Center University of California Davis Davis California USA National Instrumentation Center for Environmental Management Seoul National University Seoul Korea 湖南省蔬菜研究所

辣椒(Capsicum annuum)是美洲最古老的驯化作物之一,在全世界被广泛种植。本研究对CM334(墨西哥地方品种)进行了全基因组测序和组装(覆盖度为186.6×),同时还对另外两个栽培种和一个野生种分别进行了重测序和从头(de novo)测序。结果表... 详细信息

辣椒(Capsicum annuum)是美洲最古老的驯化作物之一,在全世界被广泛种植。本研究对CM334(墨西哥地方品种)进行了全基因组测序和组装(覆盖度为186.6×),同时还对另外两个栽培种和一个野生种分别进行了重测序和从头(de novo)测序。结果表明辣椒基因组大小约为番茄的4倍,辣椒基因组上存在大量gypsy转座子和花椰菜病毒家族元件的积累。结合转录组综合分析认为,辣椒素合成酶基因表达模式的改变及新功能化是导致辣椒素生物合成的原因,研究还发现辣椒与番茄在乙烯合成及果实成熟调控方面存在明显不同的分子模式。辣椒参考基因组的发布为辣椒营养品质和药用价值的改善提供了重要平台。

关键词：基因组测序辣椒素参考基因 Capsicum 转座子辣椒果实分子模式生物合成基因表达模式基因组大小

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小腿截肢残端假体的实验研究

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中国康复医学杂志 2003年第9期18卷 548-551页

作者：赵文汝 gregory A.Zych D.O. 王秀汝周庆芬索广文首都医科大学宣武医院功能治疗科北京长椿街45号100053 Department of Orthopedics & Rehabilitation University of Miami School of Medicine 北京矿务局创伤研究中心

目的:利用残端假体增加下肢截肢后骨残端的横截面积,降低负重时截肢残端皮肤单位面积上的压强,减少由于穿戴假肢所引起的并发症。重建离断肌肉的下位附着点,使之保持肌肉的合适初长和原有肌力,并维持肌力平衡,防止关节挛缩畸形,以保持... 详细信息

目的:利用残端假体增加下肢截肢后骨残端的横截面积,降低负重时截肢残端皮肤单位面积上的压强,减少由于穿戴假肢所引起的并发症。重建离断肌肉的下位附着点,使之保持肌肉的合适初长和原有肌力,并维持肌力平衡,防止关节挛缩畸形,以保持截肢平面上位关节的正常活动,提高截肢肢体穿戴假肢后的功能。方法:山羊10只,随机分为2组,左小腿膝下截肢后,分为对照组和假体放置组。假体采用超高分子聚乙烯材料制成,呈蘑菇状外观。术后穿戴假肢开始负重。观察站立和行走的时间,残端皮肤情况,并进行骨残端组织学检查。结果:假体放置组羊能在截肢术后较早穿戴假肢,负重站立和行走,无残端皮肤溃疡。假体与残端骨接合紧密,肌腱与假体连接良好,坚固。未发现任何假体放置后的不良反应和并发症。结论:截肢后骨残端安放假体能明显增加骨残端横截面积,很好保持残肢末端的圆锥形,加之假体材料的缓冲作用,明显减少截肢骨残端与假肢接受腔间软组织单位面积上的压强,使之能较早安装假肢,减少穿戴假肢所引起的并发症,增加假肢穿戴后的肢体功能。

关键词：小腿截肢残端实验人工假体并发症

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Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic

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stroke & Vascular Neurology 2021年第4期6卷 542-552,I0026-I0032页

作者： Thanh N nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri salvatore Mangiafico David Ozretic Vanessa Chalumeau saima Ahmad Umair Rashid syed Irteza Hussain seby john Emma Griffin john Thornton jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy nguyen steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun shin Pedro sC Magalhaes Raghid Kikano santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem sivan-Hoffmann Roberto Crosa Markus Möhlenbruch simon Nagel Hosam Al-Jehani sunil A sheth Victor s Lopez Rivera James E siegler Achmad Fidaus sani Ajit s Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin soo Lee Ji Man Hong Robert Fahed gregory Walker Eiji Hagashi steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis silva Teddy Y Wu simon john Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh stephen Winters johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke shimbo Yusuke sug Neurology RadiologyBoston Medical CenterBostonMassachusettsUSA Neurology Marcus Stroke&Neuroscience CenterGrady Memorial HospitalEmory University School of MedicineAtlantaGAUSA Radiology Radiation OncologyBoston University School of MedicineBostonMassachusettsUSA Neurology National Hospital Organization Osaka National HospitalOsakaJapan Neurosurgery National Hospital Organization Osaka National HospitalOsakaJapan Neurology Alexandria UniversityAlexandriaEgypt Radiology Boston Medical CenterBostonMassachusettsUSA Department of Neurology Xinqiao HospitalChongqingChina Neurosurgery University of Cape TownRondeboschWestern CapeSouth Africa Neurosurgery Interventional NeuroradiologyClinica La Sagrada FamiliaBuenos AiresArgentina Neuroradiologie Neurologie VasculaireHospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Neurologie Vasculaire Hospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Interventional Neuroradiology Fondation Ophtalmologique Adolphe de RothschildParisÎle-de FranceFrance Neurology Hospital Geral de FortalezaFortalezaBrazil Interventional Neuroradiology Hospital Geral de FortalezaFortalezaBrazil Neuroradiology Nottingham University Hospitals NHS TrustNottinghamUK Department of Neurosurgery Kobe City Medical Center General HospitalKobeHyogoJapan Interventional Neurovascular Unit University Hospital CareggiFirenzeToscanaItaly Neuroradiology University Hospital Centre ZagrebZagrebCroatia Interventional Neuroradiology Hopital BicetreLe Kremlin-BicetreFrance stroke and Interventional Neuroradiology Lahore General HospitalLahorePakistan Neurological Institute Cleveland Clinic Abu DhabiAbu DhabiUAE Department of Radiology Beaumont HospitalDublinIreland Neurology Stroke UnitHospital-Estadual CentralVitoriaBrazil Neuroradiology Instituto de Neurocirugia Dr AsengoSantiagoChile Interventional Neuroradiology Institut National de NeurologieTunisTunisia Neurology Boston Medical CenterBostonMassachusettsUSA Neurosurgery Boston Medical Center

Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(sAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar *** We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of sAH,aneurysmal sAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,*** 3-month cumulative volume,monthly volumes for sAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal *** There was a significant decline in sAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,psation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative *** analysis was noted for aneurysmal sAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,pse in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in sAH admissions in this *** There was a relative decrease in the volume of sAH hospitalisations,aneurysmal sAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 *** findings in sAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.

关键词： diagnosis representing subarachnoid

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