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Recent Advancements on Three‑Dimensional Electrospun Nanofiber Scaffolds for Tissue Engineering

Advanced Fiber Materials 2022年第5期4卷 959-986页

作者： Yujie Chen Xutao Dong Muhammad Shafiq gregory myles Norbert Radacsi Xiumei Mo Shanghai Engineering Research Center of Nano‑Biomaterials and Regenerative Medicine State Key Laboratory for Modification of Chemical Fibers and Polymer MaterialsCollege of ChemistryChemical Engineering and BiotechnologyDonghua UniversitySongjiangShanghai 201600China School of Engineering Institute for Materials and ProcessesThe University of EdinburghKing’s BuildingsEdinburgh EH93FBUnited Kingdom

Electrospinning is widely accepted as a technique for the fabrication of nanofibrous three-dimensional(3D)scaffolds which mimic extracellular matrix(ECM)microenvironment for tissue engineering(TE).Unlike normal densely-packed two-dimensional(2D)nanofibrous membranes,3D electrospun nanofiber scaffolds are dedicated to more precise spatial control,endowing the scaffolds with a sufficient porosity and 3D environment similar to the in vivo settings as well as optimizing the properties,including injectability,compressibility,and ***,the 3D morphology regulates cellular interaction and mediates growth,migration,and differentiation of cell for matrix *** variation among scaffold structures,functions and applications depends on the selection of electrospinning materials and methods as well as on the post-processing of electrospun *** review summarizes the recent new forms for building electrospun 3D nanofiber scaffolds for TE applications.A variety of approaches aimed at the fabrication of 3D electrospun scaffolds,such as multilay-ering electrospinning,sacrificial agent electrospinning,wet electrospinning,ultrasound-enhanced electrospinning as well as post-processing techniques,including gas foaming,ultrasonication,short fiber assembly,3D printing,electrospraying,and so on are discussed,along with their advantages,limitations and ***,the current challenges and prospects of 3D electrospun scaffolds are rationally discussed,providing an insight into developing the vibrant fields of biomedicine.

关键词： Electrospun Nanofibers Three-dimensional Tissue engineering Regenerative medicine Scaffold Polymer

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门诊手术麻醉协会关于手术后恶心呕吐的处理指南

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麻醉与镇痛 2008年第6期4卷 12-26,43页

作者： Tong J. Gan, MD Tricia A. Meyer, PharmD, MS Christian C. Apfel, MD, PhD Frances Chung, FRCPC Peter J. Davis, MD Ashraf S. Habib, MB, FRCA Vallire D. Hooper,MSN, RN, CPAN, FAAN Anthony L. Kovac,MD Peter Kranke, MD, PhD, MBA Paul myles, MD Beverly K. Philip, MD gregory Samsa, PhD Daniel I. Sessler, MD James Temo, CRNA, MSN, MBA Martin R. Tramer, MD, DPhil Craig Vander Kolk,MD Mehernoor Watcha, MD 谢郭豪(译) 方向明(校) Department of Anesthesiology Duke University Medical Center Durham North Carolina Consultant Anesthesiologist University of Wuerzburg WuerzburgGermany Department of Anesthesia and Perioperative Care UCSF Medical Center at Mt. Zion San FranciscoCalifornia Department of Anesthesia University of Toronto Toronto Canada Department of Anesthesi-ology and Pediatrics University of Pittsburgh School of Medicine Pittsburgh Pennsylvania School of Nurs-ing Medical College of Georgia Augusta Georgia Department of Anesthesiology University of KansasMedical Center Kansas City Kansas Consultant Anesthesiologist University of Wuerzburg WuerzburgGermam Department of Anesthesia and Perioperative Medicine Alfred Hospital Monash University Mel-bourne Australia Department of Anesthesiology Perioperative and Pain Medicine Brigham and Women'sHospital Harvard Medical School Boston Massachusetts Department of Biometry and Bioinformatics Duke University Medical Center Durham North Carolina Department of OUTCOMES RESEARCH TheCleveland Clinic Cleveland Ohio Duke University Nurse Anesthetist Program Durham North Caro-lina Division of Anesthesiology Geneva University Hospitals and Faculty of Medicine Geneva Switzer-land Department of Surgery Division of Plastic Surgery Johns Hopkins University School of Medicine Bal-timore Maryland Department of Anesthesiology Texas Children's Hospital Houston Texas 不详

本指南是在门诊手术麻醉协会发起下，由国际专家组编撰而成。该专家组成员涉及与手术后恶心、呕吐（PONV）相关的多个学科，他们审慎的评估了当前关于PONV的医学文献，为PONV高风险的成年及儿童外科手术患者提供了循证医学的参考工具。... 详细信息

本指南是在门诊手术麻醉协会发起下，由国际专家组编撰而成。该专家组成员涉及与手术后恶心、呕吐（PONV）相关的多个学科，他们审慎的评估了当前关于PONV的医学文献，为PONV高风险的成年及儿童外科手术患者提供了循证医学的参考工具。指南的重点是识别成人及儿童患者中发生PONV的危险因素；推荐降低PONV基础风险的方法；甄别出对PONV进行预防性治疗最为有效的单一药物及联合用药方案；推荐对已发生的PONV的治疗方法；并为具有较高PONV风险的患者提供了处理流程。

关键词：手术后恶心呕吐手术麻醉指南协会门诊 PONV 外科手术患者联合用药方案

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