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The variation of DOM during long distance water transport by the China South to North Water Diversion Scheme and impact on drinking water treatment

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Frontiers of Environmental Science & Engineering 2024年第5期18卷 85-100页

作者： Hankun Yang Yujuan Li Hongyu Liu Nigel J.D.graham Xue Wu Jiawei Hou Mengjie Liu Wenyu Wang Wenzheng Yu State Key Laboratory of Environmental Aquatic Chemistry Key Laboratory of Drinking Water Science and TechnologyResearch Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing100085China School of Environment and Municipal Engineering Qingdao Technological UniversityQingdao266033China Colleges of Forestry Northeast Forestry UniversityHarbin150006China Department of Civil and Environmental Engineering Imperial College LondonSouth Kensington CampusLondonSW7 2AZUK School of Chemistry and Chemical Engineering Beijing Institute of TechnologyBeijing100081China State Key Laboratory of Separation Membrane Processes School of Environment Science and EngineeringTiangong UniversityTianjin300387China

In this study,samples were taken from three locations,upstream to downstream,along the central route project of the China South to North Water Diversion(SNWD)scheme in summer and *** were used to reveal the variations of dissolved organic matter(DOM)during the water transfer process,and the effects of these variations on drinking water treatment and disinfection by-products formation potential(DBPs-FP).The results showed that polysaccharides accumulate in summer and reduce in winter with flow distance,which has an important effect on the overall properties of DOM,as well as on the performance of coagulation,ultrafiltration,and the formation of *** substances,and their hydrophilic content,also increased in summer and decreased in winter with flow *** contrast,the concentration of small organic substances(MW≤1000 da)increased in both summer and winter with flow distance,which affected both nanofiltration(NF)membrane fouling and *** results provide a useful case study of spatial and temporal changes in raw water DOM during long distance water transfer and their impact on the treatment and quality of drinking water from the SNWD.

关键词： Long-distance water transfer The China South to North Water Diversion Scheme Coagulation Membrane filtration Disinfection by-products

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My mother is looking blue

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World Journal of Emergency Medicine 2019年第4期10卷 251-252页

作者： Howard Tat Chun Chan Anselm Wang Hei Hui Colin graham Joseph Walline Department of Accident and Emergency Medicine Hong Kong Hospital AuthorityPrince of Wales HospitalShatinHong KongChina Accident and Emergency Medicine Academic Unit The Chinese University of Hong KongPrince of Wales HospitalShatinHong KongChina

Dear editor,A 76-year-old Chinese female presented by ambulance to the Emergency Department complaining of dizziness,headache and *** son claimed that the patient“turned blue”three hours prior to onset of the patient’s *** noted the patient’s SpO2 was 83%on room air with no improvement with a nonrebreather *** medical history was signifi cant for diabetes and ***,social and medication history were non-contributory.

关键词： mother looking blue Emergency Department

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Guidelines for Language Classroom lnstruction（Ⅱ）

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基础教育外语教学研究 2008年第10期 38-42页

作者： graham Crookes Craig Chaudron

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广州生物库队列人群心脑血管病相关基因多态性研究

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中华预防医学杂志 2010年第1期44卷 65-69页

作者：刘斌江朝强 graham Neil Thomas 劳向前林洁明岳晓军张维森朱彤林大庆广州市第十二人民医院分子流行病研究室 510620 中国香港大学社会医学系

目的应用Taqman单核苷酸多态性（SNP）分型法检测广州生物库队列人群心脑血管疾病相关基因的多态性。方法从广州生物库队列研究（GBCS）中选取2000名研究对象，应用ABI7900HT型荧光定量PCR仪并采用TaqmanSNP分型法检测该人群rs4220、rs5... 详细信息

目的应用Taqman单核苷酸多态性（SNP）分型法检测广州生物库队列人群心脑血管疾病相关基因的多态性。方法从广州生物库队列研究（GBCS）中选取2000名研究对象，应用ABI7900HT型荧光定量PCR仪并采用TaqmanSNP分型法检测该人群rs4220、rs5368及rs285等15个心脑血管疾病相关基因多态性。对检测的基因分型数据采用遗传平衡定律检测，并与国际染色体单倍型计划（HapMap）的中国人群数据进行比较。结果（1）所有15个SNP的分型数据均满足遗传平衡定律；（2）有两个SNP的分型数据与HapMap的中国人群数据差异有统计学意义（rs422028．2％对17．8％，χ^2=4．891，P=0．028；rs536822．1％对32．2％，χ^2=5．137，P=0．024）。对比美国Perlegen公司人类遗传变异研究（AFD—CHN—PANEL）、美国科学基金会等位基因频率数据库（ALFRED）、日本生物信息学协会（***）等多个基因库数据，造成本研究SNP频率不同于HapMap的中国人群数据的原因是华南人群在遗传背景上与北方人群有一定的差异。结论本研究的数据可能更能反映南方人的特性，冈此，建立大样本的广州人群心脑血管疾病相关基因多态性数据库以研究基因与环境对心脑血管疾病的影响是必要的。

关键词：心血管疾病基因多态性,单核甘酸生物标本库

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Genetic and genomic resources for Rubus breeding:a roadmap for the future

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Horticulture Research 2019年第1期6卷 260-268页

作者： Toshi M.Foster Nahla V.Bassil Michael Dossett Margaret Leigh Worthington Julie graham The New Zealand Institute for Plant and Food Research(PFR)Ltd 55 Old Mill RoadMotuekaNew Zealand USda ARS National Clonal Germplasm Repository(NCGR) 33447 Peoria Rd.CorvallisORUSA Blueberry Council(in Partnership with Agriculture and Agri-Food Canada)Agassiz Food Research Centre ColumbiaBC V0M 1A0Canada Department of Horticulture University of Arkansas316 Plant Science BuildingFayettevilleAR 72701USA The James Hutton Institute Errol RoadInvergowrieDundee DD25DAScotland

Rubus fruits are high-value crops that are sought after by consumers for their flavor,visual appeal,and health *** meet this demand,production of red and black raspberries(*** *** *** L.),blackberries(*** Rubus),and hybrids,such as Boysenberry and marionberry,is growing *** breeding programmes are continually striving to improve flavor,texture,machine harvestability,and yield,provide pest and disease resistance,improve storage and processing properties,and optimize fruits and plants for different production and harvest *** face numerous challenges,such as polyploidy,the lack of genetic diversity in many of the elite cultivars,and until recently,the relative shortage of genetic and genomic resources available for *** review will highlight the development of continually improving genetic maps,the identification of Quantitative Trait Loci(QTL)s controlling key traits,draft genomes for red and black raspberry,and efforts to improve gene *** development of genetic maps and markers,the molecular characterization of wild species and germplasm,and highthroughput genotyping platforms will expedite breeding of improved *** sequenced genomes and accurate gene models facilitate identification of genes underlying traits of interest and enable gene editing technologies such as CRISPR/Cas9.

关键词： breeding cultivar crops

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上海—埃弗尔斯堡(西德)甚长基线干涉(VLBI)实验的综合结果

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天文学报 1982年第4期 376-384页

作者：万同山钱志瀚邬林达华德铭吴文达 D.A.graham R.W.Porcas 中国科学院上海天文台西德马普射电天文研究所

1981年11月上海和埃弗尔斯堡(Effelsberg)之间完成了中—西德之间的首次VLBI实验。所有被观测的射电源都获得干涉条纹。本文发表初步分析得出的综合结果:(1)测定了上海—埃弗尔斯堡基线向量,内部符合达2—3米;(2)测定了射电源1739+52和1... 详细信息

1981年11月上海和埃弗尔斯堡(Effelsberg)之间完成了中—西德之间的首次VLBI实验。所有被观测的射电源都获得干涉条纹。本文发表初步分析得出的综合结果:(1)测定了上海—埃弗尔斯堡基线向量,内部符合达2—3米;(2)测定了射电源1739+52和1928+73的位置,精度0″.05—0″.08,均未经电离层延迟误差的改正;(3)测定了14颗河外射电源的相关流量和可见度,并发现射电源1928+73具有双源结构,间距为8.9毫角秒。

关键词：河外射电源分立射电源甚长基线干涉 VLBI 基线向量弗尔西德德国上海

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杂交改良对撒坝猪肉品质的影响——肌肉食用品质及肌纤维特性分析

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云南农业大学学报 2005年第3期20卷 396-399,427页

作者：贾俊静严达伟赵桂英李琦华陶琳丽葛长荣 Mark Jois graham H Mc Dowell 云南农业大学澳大利亚拉筹伯大学

研究选用24kg左右的去势撒坝猪及其约长撒三元杂交猪各7头,根据基因型分成两组,按活重变化分为3个试验期(前:20～35kg,中:35～60kg 和后期60～90kg),在同一试验期内饲喂同样的日粮进行饲养试验,当活重达90kg进行屠宰试验,研究杂交改良... 详细信息

研究选用24kg左右的去势撒坝猪及其约长撒三元杂交猪各7头,根据基因型分成两组,按活重变化分为3个试验期(前:20～35kg,中:35～60kg 和后期60～90kg),在同一试验期内饲喂同样的日粮进行饲养试验,当活重达90kg进行屠宰试验,研究杂交改良对云南省本地猪种撒坝猪肉品质和肌纤维特性的影响.撒坝猪通过杂交改良后,生长速度和瘦肉率显著提高,但其肉品质均有不同程度的下降.杂交后代肌肉水分显著地增加(P＜0.01),相反,肌肉粗蛋白(P＜0.05)、粗脂肪和肌内脂肪(P＜0.01)显著地降低.杂交后代的系水率、保水率、肉色、嫩度等指标均有不同程度的下降(差异不显著P＞0.05),然而,大理石纹、熟肉率、滋味、多汁性和汤味显著下降(P＜0.05).肌纤维直径和密度变化较为显著.杂交后显著地降低了腰肌、股二头肌和背最长肌肌纤维密度(P＜0.001);腰肌、股二头肌和背最长肌肌纤维密度分别降低了22.3%,22.8%和19.3%.肌纤维密度降低的主要原因是杂交后显著地增加了腰肌、股二头肌和背最长肌肌纤维直径(P＜0.01);腰肌、股二头肌和背最长肌肌纤维直径分别增加了22.5%,18.1%和18.9%.

关键词：撒坝猪肉品质肌纤维

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Seeing the wood for the trees:hyperspectral imaging for high throughput QTL detection in raspberry,a perennial crop species

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Fruit Research 2021年第1期1卷 57-67页

作者： Dominic Williams Christine A.Hackett Alison Karley Susan McCallum Kay Smith Avril Britten Julie graham James Hutton Institute Errol RoadDundee DD25DAUK Biomathematics and Statistics Scotland InvergowrieDundee DD25DAUK James Hutton Limited Errol RoadDundee DD25DAUK

Physiological and physical traits are excellent indicators of many crop characteristics,but precise phenotyping of these traits is time consuming and,therefore,limits progress in crop breeding and the speed of crop *** imaging offers an opportunity to overcome these barriers as a technique for high throughput field *** a recently developed hyperspectral imaging platform devised for plantations of the perennial crop raspberry,this study aimed to further develop the tool and test its capacity as an innovative approach for high throughput field phenotyping,data collection and *** imaging and visual crop assessments were carried out over two growing seasons in a field-grown raspberry mapping population,and data were subject to Quantitative Trait Loci(QTL)*** findings show that reflectance intensity at multiple wavelengths can be linked to known genetic markers in raspberry,and many of these‘spectral traits'are expressed consistently through the growing season and between years,for example spectral ratio 719 nm/691 nm shows up consistently as a QTL on *** traits were identified that co-located with previously mapped physical traits,such as 719 nm/691 nm and cane *** study indicates that hyperspectral imaging can be used as an innovative approach for high throughput field phenotyping of raspberry and could be transferred readily to other perennial *** approach provides a pipeline for automated field data collection and analysis that can be used for rapid QTL detection of spectral traits.

关键词： breeding consuming overcome

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前列腺癌的诊断和治疗：英国国家卫生和临床医疗优选研究所指南概要

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英国医学杂志中文版 2008年第4期11卷 243-245页

作者： John graham Fergus Macbeth Victoria Titshall 肖毅(译) 高江平(校) Leeds TeachingHospitals NHS Trust St James' s University HospitalLeeds LS9 7TF 不详

为什么阅读本概要？前列腺癌是男性最常见的恶性肿瘤之一。在英国和威尔士，每年有大约3．5万新发前列腺癌患者，并且有超过9000人因该病死亡。其临床病程可能迁延多年并且经常涉及多个不同的医疗专业。有证据表明，全英国的诊疗过程差... 详细信息

为什么阅读本概要？前列腺癌是男性最常见的恶性肿瘤之一。在英国和威尔士，每年有大约3．5万新发前列腺癌患者，并且有超过9000人因该病死亡。其临床病程可能迁延多年并且经常涉及多个不同的医疗专业。有证据表明，全英国的诊疗过程差异很大并且存在某些不规范的治疗行为。

关键词：前列腺癌患者临床医疗英国治疗研究所指南优选卫生

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Rates and impact of hepatitis on human immunodeficiency virus infection in a large African cohort

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World Journal of Gastroenterology 2013年第10期19卷 1602-1610页

作者： Nimzing Gwamzhi Ladep Patricia Aladi Agaba Oche Agbaji Auwal Muazu Placid Ugoagwu Godwin Imade graham Cooke Sheena McCormack Simon david Taylor-Robinson John Idoko Phyllis Kanki Section of Hepatology Department of MedicineImperial College LondonSt Mary's Hospital CampusLondon W2 1NYUnited Kingdom AIDS Prevention Initiative in Nigeria Jos University Teaching HospitalJos 930001Nigeria MRC Clinical Trials Unit LondonLondon NW1 2DAUnited Kingdom National Agency for the Control of AIDS Central Business DistrictAbuja 905001Nigeria Immunology and Infectious Diseases Harvard School of Public HealthBostonMA 02115-5810United States

AIM:To determine the rates and impact of hepatitis B virus(HBV) and hepatitis C virus(HCV) infections on response to long-term highly active antiretroviral therapy(HAART) in a large human immunodeficiency virus(HIV) population in ***:HBV and HCV as well as HIV infections are endemic in sub Saharan *** was a retrospective cohort study of 19 408 adults who were recruited between June 2004 and December 2010 in the AIDS Prevention Initiative in Nigeria in Nigeria programme at Jos University Teaching *** assays,including HBV surface antigen(HBsAg) and hepatitis C antibody were used to categorise hepatitis status of the *** was determined using enzyme immunoassay(EIA)(Monolisa HBsAg Ultra3;Bio-Rad).HCV antibody was tested using third generation EIA(*** Diagnostic,Bioprobes srl,Milan,Italy).HIV RNA levels were measured using Roche COBAS Amplicor HIV-1 monitor test version 1.5(Roche Diagnostics,GmbH,Mannheim,Germany) with a detection limit of 400 copies/*** cytometry was used to determine CD4+ cell count(Partec,GmbH Munster,Germany).Comparison of categorical and continuous variables were achieved using Pearson's χ 2 and Kruskal Wallis tests respectively,on MedCalc for Windows,version 9.***.0.0(MedCalc Software,Mariakerke,Belgium).RESULTS:With an overall hepatitis screening rate of over 90% for each virus;HBV,HCV and HBV/HCV were detected in 3162(17.8%),1983(11.3%) and 453(2.5%) HIV infected adults *** rate of liver disease was low,but highest among HIV monoinfected patients(29,0.11%),followed by HBV coinfected patients(15,0.08%).Patients with HBV coinfection and triple infection had higher log 10 HIV RNA loads(HBV:4.6 copies/mL vs HIV only:4.5 copies/mL,P<0.0001) and more severe immune suppression(HBV:645,55.4%;HBV/HCV:97,56.7%) prior to initiation of HAART compared to HIV mono-infected patients(1852,48.6%)(P<0.0001).Of 3025 patients who were 4.4 years on HAART and whose CD4 cell counts results at baseline a

关键词： Human immunodeficiency virus Hepatitis B Hepatitis C Africa Liver disease

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