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探索图书馆新趋势:参加第88届国际图联大会的见解和反思

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图书馆杂志 2023年第10期42卷 4-14页

作者：王超刘国英李嘉汶吴昌洪佟昕瑀傅平中山大学信息管理学院广东广州510006 温莎大学图书馆加拿大温莎N9B 3P4 澳门旅游学院图书馆中国澳门999078 东北师范大学图书馆吉林长春130024 惠特曼学院图书馆美国沃拉沃拉99362

本文介绍了笔者参加2023年在荷兰鹿特丹举行的第88届世界图书馆与信息大会(WLIC 2023)部分会议的主要见解。第88届WLIC展示了图书馆作为创新和知识中心不断发展的形象。大会以“让我们携手合作,让世界‘圕’起来”为主题,吸引了来自100... 详细信息

本文介绍了笔者参加2023年在荷兰鹿特丹举行的第88届世界图书馆与信息大会(WLIC 2023)部分会议的主要见解。第88届WLIC展示了图书馆作为创新和知识中心不断发展的形象。大会以“让我们携手合作,让世界‘圕’起来”为主题,吸引了来自100多个国家的3000多名代表,重新点燃了人们对图书馆作为充满活力知识中心的认知。本文总结了大会的10场分会,讨论的主题包括负责任的AI使用、受控数字借阅、确保图书馆可访问性以及AI在学术图书馆中的变革潜力等。与会者强调了AI的潜力,同时也突出了隐私、偏见和信息素养教育等问题。研究方法包括数据收集、观察和对学者和专业人士的访谈。讨论反思部分强调了AI在图书馆中的潜力,强调了隐私、透明度和AI素养的重要性。此外,本文还讨论了“毒性领导”、图书馆出版、网络安全和包容性工作,强调领导层必须意识到“毒性领导”的危害性,明确促进包容性、与残障社群合作、员工培训和“面向所有人的设计”的重要性。总之,本文为图书馆趋势提供了有价值的见解,提供了有关AI整合、工作场所挑战、数字借阅实践和确保包容性等方面的指导。

关键词：世界图书馆与信息大会图书馆新趋势国际图联

Philippine retinoblastoma initiative multi-eye center study 2010-2020

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 144-156页

作者： Roland Joseph D.Tan Gary John V.Mercado Patricia E.Cabrera Paulita Pamela P.Astudillo Rolando Enrique D.Domingo Josept Mari S.Poblete Charmaine grace M.Cabebe Adriel Vincent R.Te Melissa Anne S.Gonzales Jocelyn G.Sy beltran Alexis A.Aclan Jayson T.So Fatima G.Regala Kimberley Amanda K.Comia Josemaria M.Castro Mara Augustine S.Galang Aldous Dominic C.Cabanlas benedicto Juan E.Aguilar Gabrielle S.Evangelista Jo Michael Maniwan Andrei P.Martin Calvin Y.Martinez John Alfred H.Lim Rena Ivy bascuna Rachel M.Ng Kevin b.Agsaoay Kris Zanna A.Acluba-Arao Ellaine Rose V.Apostol beatriz M.Prieto Department of Ophthalmology and Visual Sciences Philippine General HospitalManila 1000Philippines Department of Ophthalmology Baguio General Hospital and Medical CenterBaguio City 2600Philippines Department of Ophthalmology Manila Doctors HospitalManila 1000Philippines Department of Ophthalmology Rizal Medical CenterPasig City 1600Philippines Department of Ophthalmology Jose B.Lingad Memorial Regional HospitalPampanga 2000Philippines Department of Ophthalmology Southern Philippines Medical CenterDavao City 8000Philippines Department of Ophthalmology East Avenue Medical CenterQuezon City 1100Philippines Department of Ophthalmology Northern Mindanao Medical CenterCagayan de Oro City 9000Philippines Department of Ophthalmology Cebu Velez General HospitalCebu City 6000Philippines Legazpi Eye Center Legazpi City 4500Philippines Department of Ophthalmology Cagayan Valley Medical CenterTuguegarao City 3500Philippines

AIM:To provide a comprehensive and more representative national data on the disease,especially on treatment options and outcomes,and to determine access of retinoblastoma patients from Luzon,Visayas and Mindanao to eye care,and determine if access is associated with delay in consultation,staging and ***:Cohort study of retinoblastoma patients seen in eleven institutions located in the three major areas of the Philippines namely Luzon,Vizayas and Mindanao from ***:Totally 636 patients,involving 821 eyes,were ***(57%)were from Luzon and were seen in institutions in Luzon(72%).Annually,58±10 new cases were seen with 71%having unilateral *** delay of consultation remained long at 9(3,17)mo,longest in patients with unilateral disease(Pbased on the International Retinoblastoma Staging System,only 35%of patients had Stage 1 while 47%already had extraocular *** was the most common treatment received by 484 patients while intravenous chemotherapy was received by *** were 250(39%)patients alive,195(31%)dead,85(13%)abandoned,17(3%)refused and 89(14%)with no ***:This study presents the largest cohort of retinoblastoma patients in the Philippines in terms of patients’and participating institutions’number and geographical location and type of institution(private and public).It also presents more comprehensive data on the treatments used and outcomes(survival,globe salvage,and vision retention rates).Delay in consultation was still long among patients leading to advanced disease stage and lower survival *** increasing capacity to diagnose and manage retinoblastoma in the country,the delay of consultation remains long primarily due to accessibility issues to eye care institutions especially in the Visayas and financial *** delay was still significant that overall survival rate remain low.

关键词： retinoblastoma Philippines clinical profile

蓖麻种质资源多样性AP-PCR与RMAPD分析

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农产品加工（下） 2012年第6期 45-49页

作者：何东王昌禄李伟杨朝晖杨桂仙杨华王玉荣陈勉华李风娟叶锋 grace.Chen 食品营养与安全教育部重点实验室天津科技大学食品工程与生物技术学院天津300457 南开大学蓖麻工程研究中心天津300071 美国农业部农科院西部研究中心美国加利福尼亚94710

为了研究国内主要商业蓖麻品种的种质资源多样性，采用AP—PCR与RMAPD分子标记方法，对来自国内不同地区的31份蓖麻品种进行分析。AP—PCR分子标记的研究结果表明，9条引物扩增的条带为5—12条，共计82条带，平均每条引物扩增出9．1条... 详细信息

为了研究国内主要商业蓖麻品种的种质资源多样性，采用AP—PCR与RMAPD分子标记方法，对来自国内不同地区的31份蓖麻品种进行分析。AP—PCR分子标记的研究结果表明，9条引物扩增的条带为5—12条，共计82条带，平均每条引物扩增出9．1条带，扩增的多态性条带为2。10条，多态率为40％．90．91％，共计53条带，平均每条引物扩增出5．89条多态性带。在9条引物中，引物S3扩增出多态性条带最高，多态率达90．91％。蓖麻种质资源的RMAPD分析结果表明，84对引物扩增的条带为5～12条，共计85条带，平均每对引物扩增出8．5条带，扩增的多态性条带为3。10条，共计56条带，平均每条引物扩增出5．6条多态性带。在84对引物中，引物A3＋b4扩增出的条带最多，多态性最高，多态率达83．3％。对AP—PCR与RMAPD分子标记的数据进行联合聚类分析表明，在遗传系数为0．56处，31份蓖麻种质被分成3大类群。2种分子标记之间的相关系数不显著（R=0．0093）。

关键词：蓖麻种质资源 AP-PCR RMAPD 多怼胜

Use of Polyclonal Antibody for the Diagnosis of Human African Trypanosomiasis

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American Journal of Molecular biology 2023年第2期13卷 127-139页

作者： Dawala Koromtili Oumar Matthew Mutinda Munyao Anne Wanjiru Mwangi Rebecca Wanjiku Waihenya Peter Kipkemboi Rotich Robinson Mugasiali Irekwa Tonny Teya Nyandwaro Caroline Wangui Njoroge Joanne Jepkemei Yego Primrose Muthoni Ndungu Sharlene Kerubo Mageto Damaris Mutethya Kilei Otilmoi Poul Stephen Nicole Sian Tanchu grace Ngendo Kanyita Shingo Inoue Lucy Gitau Samson Muuo Nzou Department of Molecular biology and biotechnology Pan-African University Institute of Basic Sciences Technology and Innovation Nairobi Kenya Centre for Microbiology Research Kenya Medical Research Institute Nairobi Kenya Nagasaki University Institute of Tropical Medicine-Kenya Medical Research Institute Project Nairobi Kenya Production Department Kenya Medical Research Institute Nairobi Kenya Zoology Department Jomo Kenyatta University for Agriculture and Technology Nairobi Kenya Department of Pharmacology and Pharmacognosy University of Nairobi Nairobi Kenya Department of Microbiology Jomo Kenyatta University for Agriculture and Technology Nairobi Kenya Department of biochemistry Microbiology and Biotechnology Kenyatta University Nairobi Kenya Center for biotechnology Research and Development Kenya Medical Research Institute Nairobi Kenya

Human African trypanosomiasis (HAT), commonly known as sleeping sickness is one of the neglected tropical diseases (NTDs), which is fatal if left untreated. Its diagnosis is a challenge since the signs and symptoms of the primary phase are not specific, the existing diagnostic methods have low sensitivity and specificity, and the available drugs have some toxicity. New, robust, and cost-effective techniques are needed for the early identification of parasites. This study aimed to assess the sensitivity and specificity of two different types of polyclonal antibodies against T. b. gambiense using antigen detection ELISA. Polyclonal antibodies against the expressed proteins Tbg I2 and Tbg I17 were produced using New Zealand white rabbits. The antibody titer measured was greater than 32 g/L after the 3rd immunization for the expressed protein Tbg I2. For the expressed protein Tbg I17, the antibody titer measured was greater than 32 g/L after the 4th immunization. The sensitivity and specificity of the Tbg I2 polyclonal antibody confirmed with Polymerase Chain Reaction (PCR) as gold standard were respectively 89.5% and 80.6%, while for the Tbg I17 polyclonal antibody, the sensitivity and specificity were respectively 92.1% and 88.9%. The area under the curve for the Tbg I2 polyclonal antibody was 0.90 ± 0.032, while for the Tbg I17 polyclonal antibody, the area under the curve was 0.92 ± 0.0. The Tbg I17 polyclonal antibody produced in New Zealand white rabbits has good sensitivity and good specificity;it can be successfully used in the diagnosis of HAT.

关键词： Human African Trypanosomiasis Polyclonal Antibody Tbg I2 Expressed Protein Tbg I17 Expressed Protein Sensitivity Specificity

Phenotypic Characterization and Prevalence of Carbapenemase-Producing Acinetobacter baumanii Isolates in Four Health Facilities in Cameroon

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Open Journal of Medical Microbiology 2023年第3期13卷 234-249页

作者： Cécile Ingrid Djuikoue benhamed Nadjia Paule Dana Djouela Djoulako Celianthe Guegang Cedric Seugnou Nana Hélène Valérie Same Njanjo Yemina grace Kombeu Christiane Kiyang Possi Rodrigue Kamga Wouambo Gandhi Ndieffouo Fosso Merimé Joel Tchinda Talokou bianca Tchounga Chimi Olivier Pomte Agbor Michael benjamin D. Thumamo Pokam Nicolas Antoine-Moussiaux Department of Public Health Faculty of Health Sciences of the Université des Montagnes Bangangté Cameroon American Society for Microbiology Bangangte Cameroon Université des Sciences et de la Technologie d’Oran Mohamed boudiaf Oran Algeria Faculty of Medicine Sorbonne Université Paris France Estuary Academic and Strategic Institute (IUEs/INSAM) Douala Cameroon Faculty of Medicine and Pharmaceutic Sciences University of Douala Douala Cameroon Division of Hepatology Department of Medicine II Leipzig University Medical Center University of Leipzig Leipzig Germany Centre Hospitalier Dominicain St Martin de Porres Yaounde Cameroon Department of Medical Laboratory Science Faculty of Health Sciences University of Buea Buea Cameroon Faculty of Veterinary Medicine University of Liège Liège Belgium

background and Objective: Nowadays, the clinical utility of carbapenems is threatened by the emergence of resistant bacteria, favored by its increasing use. According to the WHO, Acinetobacter baumannii: nosocomial infection agent, tops the list of priority antibiotic-resistant pathogens, considered to be the riskiest for humans. This study sought to determine the prevalence of carbapenemase-producing Acinetobacter baumannii strains in four health facilities in the Center and Littoral regions of Cameroon and the associated risk factors. Materials and Method: An analytical cross-sectional study was conducted over a six-month period from January to June 2022. All suspicious A. baumanii isolates obtained from pathological samples at the bacteriology laboratory of the different health facilities were systematically collected and re-identified. Re-identification and antimicrobial susceptibility Testing (AST) were performed using the VITEK 2 System and the Kirby-bauer method according to the guidelines of the Clinical and Laboratory Standards Institute (CLSI). Detection and phenotypic characterization of carbapenemases was performed according to adequate standard procedures. Results: A total of 168/226 clinical isolates of Acinetobacter baumannii were confirmed after re-identification, among which 52.69% derived from male patients, 55.09% from participants aged between 10 - 39 years old, and 46.71% from pus samples. A very high resistance rates to all families of antibiotics was noted, except to colistin (10.2%). 40.12% of these isolates produced carbapenemase, represented by 62.69% of class b and 37.31% of class A. Carbapenemase production was observed only at HMR1, Centre region and at Laquintinie hospital, Littoral region with 53.33% and 50% respectively, even if there is no significant difference (P = 0.81). In addition, frequent hospitalisation was significantly associated to the production of carbapenemase among A. baumanii (Adjusted-OR = 16.53, P-value 0.0001). Con

关键词： Acinetobacter baumannii Resistance Carbapenemases Health Facilities

Improving the accuracy of grace Earth’s gravitational eld using the combination of di erent inclinations

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Progress in Natural Science:Materials International 2008年第5期 555-561页

作者： Wei Zhenga, Chenggang Shaoa, Jun Luo a, Houze Xu b a Department of Physics, Huazhong University of Science and Technology, Wuhan 430074, China b Institute of Geodesy and Geophysics, Chinese Academy of Sciences, Wuhan 430077, China

In this paper, the grace Earth’s gravitational eld complete up to degree and order 120 is recovered based on the combination of di erent inclinations using the energy conservation principle. The results show that because di erent inclinations of satellite are sensitive to the geopotential coe cients with di erent degrees l and orders m, the design of grace exploiting 89° inclination can e ectively improve the accuracy of geopotential zonal harmonic coe cients. However, it is less sensitive to the geopotential tesseral harmonic coef- cients. Accordingly, the second group of grace exploiting lower inclination is required to determine high-accurately the geopotential tesseral harmonic coe cients and cover the shortage of the single group of grace exploiting 89o inclination. Two groups of grace individually exploiting 89° + (82°–84°) inclinations are the optimal combination of the Earth’s gravitational eld recovery complete up to degree and order 120. In the degree 120, the joint accuracy of cumulative geoid height based on two groups of grace individually exploiting 89° and 83° inclinations is averagely two times higher than the accuracy of a group of grace exploiting 89° inclination.

关键词： grace Earth’s gravitational eld Inclination Energy conservation principle

Contemporary nationwide trends in major adverse cardiovascular events in young cannabis users without concomitant tobacco,alcohol,cocaine use

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World Journal of Cardiology 2024年第9期16卷 512-521页

作者： Rupak Desai Priyatham Gurram Adil S Mohammed Rishabh b Salian Shanmukh Sai Pavan Lingamsetty Sandeep Guntuku Ravi Venkata Sai Krishna Medarametla Rawnak Jahan Zainab Muslehuddin Paritharsh Ghantasala Department of Outcomes Research Independent ResearcherAtlantaGA 30033United States Department of Internal Medicine Central Michigan University College of MedicineSaginawMI 48602United States Department of Medicine Kasturba Medical CollegeMangalore 575001India Department of Medicine Mamata Medical CollegeKhammam 507002India Department of Medicine Bangladesh Medical CollegeDhaka 110015Bangladesh Department of Internal Medicine Wayne State UniversitySinai Grace HospitalDetroit Medical CenterDetroitMI 48201United States

bACKGROUND Cannabis use has increased among young individuals in recent *** dependent cannabis use disorder(CUD)has been associated with various cardiac events,its effects on young adults without concurrent substance use remain *** To examine trends in hospitalizations for major adverse cardiac and cerebrovascular events(MACCE)in this *** used the National Inpatient Sample(2016-2019)to identify hospitalized young individuals(18-44 years),excluding those with concurrent substance usage(tobacco,alcohol,and cocaine).They were divided into CUD+and CUD-.Using International Classification of Diseases-10 codes,we examined the trends in MACCE hospitalizations,including all-cause mortality(ACM),acute myocardial infarction(AMI),cardiac arrest(CA),and acuteischemic stroke(AIS).RESULTSOf 27.4 million hospitalizations among young adults without concurrent substance abuse,4.2%(1.1 million)hadco-existent *** CUD+group,hospitalization rates for MACCE(1.71%vs 1.35%),AMI(0.86%vs 0.54%),CA(0.27%vs 0.24%),and AIS(0.49%vs 0.35%)were higher than in CUD-group(Pble between 2016 and *** CUD+group had higher rates of MACCE,but the rising trends were more apparent in the CUD-group ***,the CUD+group had lower ACM rates than the CUD-group.

关键词： Cannabis Major adverse cardiac and cerebrovascular events Myocardial infarction Cardiac arrest Stroke Allcause mortality Young adults Trends

A Novel,Monomeric C18 bonded Phase for High-Resolution Peptide Separations

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A Novel,Monomeric C18 Bonded Phase for High-Resolution Pepti...

The amazing potential of fungi:50 ways we can exploit fungi industrially

8th Chinese International Peptide Symposium

作者： Reno NGUYEN Cindy Lou CHEPANOSKE Nathan VerbERKMOES Michael b.STRADER Larry GROSS grace Vydac Prolexys Pharmaceuticals Chemical Sciences Division Oak Ridge National Laboratory Howard Hughes Medical Institute University of California San Diego

The separation of protein enzymatic digests by RPHPLC is a standard method in protein research and in the development of well-characterized biotechnology pharmaceuticals. Resolution on silicabased RP columns is determined by the nature of the silica, as well as, the silanes and the chemistry that is used to bond them to the stationary phase. Typically, 300A C18 chemistries have carbon coverage ranging from 2.8 to 3.6 μmol/m2. The performance of a novel, monomeric bonded 300A C18 adsorbent with carbon coverage > 4 μmol/m2 is described. The resolution and sensitivity of this stationary phase was assessed using an LC-MS/MS analysis of several tryptic digests including: di

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Fungal Diversity 2019年第4期97卷 1-136页

作者： Kevin D.Hyde Jianchu Xu Sylvie Rapior Rajesh Jeewon Saisamorn Lumyong Allen grace T.Niego Pranami D.Abeywickrama Janith V.S.Aluthmuhandiram Rashika S.brahamanage Siraprapa brooks Amornrat Chaiyasen K.W.Thilini Chethana Putarak Chomnunti Clara Chepkirui boontiya Chuankid Nimali I.de Silva Mingkwan Doilom Craig Faulds Eleni Gentekaki Venkat Gopalan Pattana Kakumyan Dulanjalee Harishchandra Hridya Hemachandran Sinang Hongsanan Anuruddha Karunarathna Samantha C.Karunarathna Sehroon Khan Jaturong Kumla Ruvishika S.Jayawardena Jian-Kui Liu Ningguo Liu Thatsanee Luangharn Allan Patrick G.Macabeo Diana S.Marasinghe Dan Meeks Peter E.Mortimer Peter Mueller Sadia Nadir Karaba N.Nataraja Sureeporn Nontachaiyapoom Meghan O’brien Watsana Penkhrue Chayanard Phukhamsakda Uma Shaanker Ramanan Achala R.Rathnayaka Resurreccion b.Sadaba birthe Sandargo binu C.Samarakoon Danushka S.Tennakoon Ramamoorthy Siva Wasan Sriprom T.S.Suryanarayanan Kanaporn Sujarit Nakarin Suwannarach Thitipone Suwunwong benjarong Thongbai Naritsada Thongklang Deping Wei S.Nuwanthika Wijesinghe Jake Winiski Jiye Yan Erandi Yasanthika Marc Stadler Key Laboratory for Plant Diversity and biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand World Agroforestry Centre East and Central AsiaKunming 650201YunnanPeople’s Republic of China Mushroom Research Foundation 128 M.3 Ban Pa Deng T.PaPaeA.Mae TaengChiang Mai 50150Thailand Aix Marseille Université INRAUMR1163 BBF13288 Marseille Cedex 09France beijing Key Laboratory of Environment Friendly Management on Fruit Diseases and Pests in North China Center of Plant and Environment ProtectionBeijing Academy of Agriculture and Forestry SciencesBeijing 100097People’s Republic of China Center of Chemical Innovation for Sustainability Mae Fah Luang UniversityTasudMuangChiang Rai 57100Thailand Center of Excellence in Microbial Diversity and Sustainable Utilization Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Center for Mountain Ecosystem Studies Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanPeople’s Republic of China Institute of Fungal Research School of Life Science and TechnologyUniversity of Electronic Science and Technology of ChinaChengdu 611731People’s Republic of China Department Microbial Drugs Helmholtz Centre for Infection Researchand German Centre for Infection Research(DZIF)partner site Hannover-BraunschweigInhoffenstrasse 738124 BrunswickGermany Department of biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Department of Chemistry and biochemistry The Ohio State UniversityColumbusOH 43210USA Department of Chemistry University of Science and TechnologyBannuKhyber PakhtunkhwaPakistan Department of Crop Physiology University of Agricultural SciencesGKVKBengaluruKarnataka 560065India Department of Entomology and Plant Pathology Faculty of AgricultureChiang Mai Univers

Fungi are an understudied,biotechnologically valuable group of *** to the immense range of habitats that fungi inhabit,and the consequent need to compete against a diverse array of other fungi,bacteria,and animals,fungi have developed numerous survival *** unique attributes of fungi thus herald great promise for their application in biotechnology and ***,fungi can be grown with relative ease,making production at scale *** search for fungal biodiversity,and the construction of a living fungi collection,both have incredible economic potential in locating organisms with novel industrial uses that will lead to novel *** manuscript reviews fifty ways in which fungi can potentially be utilized as *** provide notes and examples for each potential exploitation and give examples from our own work and the work of other notable *** also provide a flow chart that can be used to convince funding bodies of the importance of fungi for biotechnological research and as potential *** have provided the world with penicillin,lovastatin,and other globally significant medicines,and they remain an untapped resource with enormous industrial potential.

关键词： biocontrol biodiversity biotechnology Food Fungi Mushrooms