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Constructions: A ne. the.re.ical approach to language

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外国语 2003年第3期26卷 1-11页

作者： Ade.e.e. goldberg (Linguistics De.artme.t, Unive.sity of Illinois, Urbana, IL 61801-0168, USA) LinguisticsDe.artmant UniversityofIllinoisUrbanaIL61801-0168USA

A ne. the.re.ical approach to language.has e.e.ge. in the.past 10-15 ye.rs that allows linguistic obse.vations about form-me.ning pairings constructions — to be.state. dire.tly. Constructionist approache. aim to account for the.full range.of facts about language. without assuming that a particular subse. of the.data is part of a privile.e. 揷ore. Re.e.rche.s argue.that unusual constructions she. light on more.ge.e.al issue., and se.ve.to illuminate.what is re.uire. for a comple.e.account of language.

关键词：语言语言学理论语法综述建构理论搭配

A Le.ically Base. Proposal of Argume.t Structure.Me.ningi

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外国语 2005年第1期28卷 3-13页

作者： Ade.e.e.goldberg De.in Case.hise. Nitya Se.huraman Prince.on Unive.sity Princeton UniversityIndiana UniversityUSA

Childre. conse.vative.y produce.syntactic patte.ns on a ve.b-by-ve.b basis (Akhtar and Tomase.lo, 1997;Bake., 1979; Bate. and MacWhinne., 1987; Bowe.man, 1982; Braine. 1976; Brooks and Tomase.lo, 1999;Grope. e. al., 1989; Ingram and Thompson, 1996; Lie.e. e. al., 1997; MacWhinne., 1982; Olguin and Tomase.lo, 1993; Schle.inge., 1982; Tomase.lo, 1992). Ultimate.y, howe.e.,

关键词：构词法副词词汇语法

Asse.sing ke.oid re.urre.ce.following surgical e.cision and radiation

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Burns & Trauma 2020年第1期8卷 34-40页

作者： Michae. H.Gold Mark S.Ne.tor Brian Be.man David goldberg Gold Skin Care.Ce.te. 2000 Richard Jones RoadSuite 220NashvilleTN 37215 Ce.te. for Clinical and Cosme.ic Re.e.rch 2925 NE 199th StSuite 205AventuraFL 33180 De.artme.t of De.matology and Cutane.us Surge.y University of Miami Miller School of MedicineMiamiFL Skin Lase.&Surge.y Spe.ialists of NY/NJ 110 E.55th Street13th floorNew YorkNY 10022

Ke.oids are.a fibroprolife.ative.disorde. that can re.ult from a cutane.us injury to the.re.icular *** rate. as high as 100%have.be.n re.orte. following surgical e.cision ***,a varie.y of post-surgical te.hnique. have.be.n e.ploye. to pre.e.t ke.oid re.urre.ce.including the.use.of *** nume.ous studie. have.shown post-e.cisional X-rays,e.e.tron be.m,lase.s and brachythe.apy can re.uce.the.rate.of ke.oid re.urre.ce.nume.ous inconsiste.cie.,including a wide.range.of de.initions for ke.oid re.urre.ce.make.it difficult to compare.study *** re.ie. aims to e.amine.the.various me.ns for de.ining ke.oid re.urre.ce.in clinical trials involving the.use.of radiation *** of the.Cochrane.Library and PubMe. we.e.pe.forme. to ide.tify the.available.information for post-surgical ke.oid re.urre.ce.following radiation *** ide.tifie. study was re.ie.e. for patie.t followup and crite.ia use. to de.ine.ke.oid *** se.rch re.ults include. clinical studie. with e.te.nal be.m radiation,brachythe.apy and supe.ficial radiation *** studie. did not include.a de.inition of ke.oid re.urre.ce.or de.ine. re.urre.ce.only as the.re.urn of scar *** studie. de.ine. ke.oid re.urre.ce.base. on patie.t se.f-asse.sme.t que.tionnaire.,symptoms and scar e.e.ation and change. in Kyoto Scar Scale.Japan Scar Workshop Scale.and Vancouve. Scar Scale.*** re.ults of this re.ie. indicate.ke.oide.tomy followe. by radiation the.apy provide.satisfactory re.urre.ce.rate.;howe.e.,clinical studie. e.aluating the.e.tre.tme.ts do not de.cribe.tre.tme.t outcome. or use.diffe.e.t de.initions of ke.oid ***,re.urre.ce.rate. vary wide.y,making comparisons across studie. *** re.urre.ce.should be.cle.rly de.ine. using both obje.tive.and subje.tive.me.sure..

关键词： Ke.oid Ke.oid scar Re.urre.ce e.te.nal be.m radiation Brachythe.apy Supe.ficial radiation the.apy

Pe.formance.characte.istics of re.rograde.single.balloon e.doscopy: A single.ce.te. e.pe.ie.ce

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World Journal of Gastrointe.tinal e.doscopy 2016年第15期8卷 501-507页

作者： Kaci e.Christian Karan Kapoor e.ic M goldberg De.artme.t of Me.icine Division of Gastroenterology University of Maryland Medical Center

AIM: To e.aluate.the.te.hnical succe.s, diagnostic yie.d(DY) and the.ape.tic pote.tial of re.rograde.single.balloon e.te.oscopy(rS Be.. Me.HODS: A re.rospe.tive.re.ie. of 136 rS Be.proce.ure. pe.forme. at a te.tiary acade.ic re.e.ral ce.te. from January 2006 and Se.te.be. 2013 was comple.e.. Patie.t characte.istics including age. ge.de. and inpatie.t status we.e.colle.te.. The.indication for the.proce.ure.was cate.orize. into one.of thre. groups: Obscure.gastrointe.tinal ble.ding(GIB), e.aluation for Crohn's dise.se.and abnormal imaging. Proce.ural characte.istics including inse.tion de.th(ID), proce.ure.time. concordance.with pre.proce.ural imaging and complications we.e.also re.orde.. Lastly, DY, de.ine. as the.pe.ce.tage.of case. producing e.the. a de.initive.diagnosis or findings that could e.plain clinical symptoms and the.ape.tic yie.d(TY), de.ine. as the.pe.ce.tage.of case. in which a de.initive.inte.ve.tion was pe.forme., we.e.de.e.mine.. Mucosal tattooing and biopsy alone.we.e.not include. in the.TY. Re.ULTS: A total of 136 rS Be.proce.ure. we.e.ide.tifie.. Me.n patie.t age.was 57.5(± 16.2) ye.rs, 67(49.2%) we.e.male. and 110(80.9%) proce.ure. we.e.pe.forme. on an outpatie.t basis. Indications for rS Be.include. GIB in 55(40.4%), e.aluation of inflammatory bowe. dise.se.IBD) in 29(21.3%), and imaging sugge.tive.of pathology othe. than GIB or IBD in 43(31.6%). Nine.6.6%) rS Be. we.e.pe.forme. for othe. indications. Me.n ID was 68.3(± 39.3) cm proximal to the.ile.ce.al valve.and me.n time.to comple.ion was 41.7(± 15.5) min. Ove.all, 73(53.7%) case. we.e.diagnostic and 25(18.4%) case. we.e.the.ape.tic in which inte.ve.tions(argon plasma coagulation, stricture.dilatation, polype.tomy, e.c.) we.e.pe.forme.. Pre.proce.ural imaging was pe.forme. in 88(64.7%) patie.ts. e.doscopic concordance.of positive.imaging findings was se.n in 31(35.2%) case.. Follow up data was available.in 93(68.4%) patie.ts; 2(2.2%) re.orte. post-proce.ural abdominal pain within 30 d follow

关键词： Re.rograde Single.balloon e.te.oscopy e.doscopy

消旋棉酚及其旋光异构体对小鼠乳酸脱氢酶(LDH)抑制作用的比较研究

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生殖与避孕 1991年第1期11卷 20-25页

作者：梁志国 Kim IC Walle. DP goldberg e 国家计划生育委员会科学技术研究所美国芝加哥伊利诺伊大学药物所美国西北大学生物系

本文用消旋棉酚及其旋光异构体比较研究了对纯化小鼠肝脏LDH-A_4,心脏LDH-B_4和睾丸LDH-C_4的抑制作用。其抑制程度与实验温度和棉酚剂量有关。37℃时的抑制作用比25℃时强得多。棉酚低浓度(1～4μM)时三种酶对同一种棉酚的反应有明显... 详细信息

本文用消旋棉酚及其旋光异构体比较研究了对纯化小鼠肝脏LDH-A_4,心脏LDH-B_4和睾丸LDH-C_4的抑制作用。其抑制程度与实验温度和棉酚剂量有关。37℃时的抑制作用比25℃时强得多。棉酚低浓度(1～4μM)时三种酶对同一种棉酚的反应有明显的不同,而在较高棉酚浓度(20～100μM)时棉酚对三种酶的抑制作用大体相同。对同一种酶来说,消旋棉酚,右旋棉酚和左旋棉酚对LDH的抑制作用并无差异。结论是,棉酚及其旋光异构体并不特异地抑制LDH-C_4,而在离体试验中,不能反映棉酚在体内试验中所表现的光学立体结构特异性。

关键词：棉酚旋光异构体 NADH LDH同功酶

Anti-ste.totic and anti-fibrotic e.fe.ts of the.KCa3.1 channe. inhibitor, Se.icapoc, in non-alcoholic live. dise.se

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World Journal of Gastroe.te.ology 2017年第23期23卷 4181-4190页

作者： latha paka david e.smith dawoon jung siobhan mccormack ping zhou bin duan jing-song li jiaqi shi yong-jie.hao kai jiang michae. yamin itzhak d goldberg prakash narayan De.artme.t of Re.e.rch and De.e.opme.t Angion Biomedica Corp.

To e.aluate.a calcium activate. potassium channe. (KCa3.1) inhibitor atte.uate. live. dise.se.in mode.s of non-alcoholic fatty live. dise.se.(NAFLD).Me.HODSWe.have.pe.forme. a se.ie. of in vitro and in vivo studie. using the.KCa3.1 channe. inhibitor, Se.icapoc. e.ficacy studie. of Se.icapoc we.e.conducte. in toxin-, thioace.amide.(TAA) and high fat die. (HFD)-induce. mode.s of live. fibrosis in rats. e.ficacy and pharmacodynamic e.fe.ts of Se.icapoc was de.e.mine. through biomarke.s of apoptosis, inflammation, ste.tosis and *** of KCa3.1 e.pre.sion was re.orde. in TAA-induce. and high fat die.-induce. live. dise.se. Tre.tme.t with Se.icapoc de.re.se. palmitic acid-drive. He.G2 ce.l de.th. (P e.finding that Se.icapoc re.uce. lipid-drive. apoptosis in He.G2 ce.l culture.. In animals fe. a HFD for 6 wk, co-tre.tme.t with Se.icapoc, (1) re.uce. non-alcoholic fatty live. dise.se.(NAFLD) activity score.(NAS) (0-8 scale., (2) de.re.se. ste.tosis and (3) de.re.se. he.atic lipid conte.t (Oil Re. O, P e.icle.. Randomization of TAA animals and HFD fe. animals to Se.icapoc was associate. with a de.re.se.in live. fibrosis as e.ide.ce. by hydroxyproline.and Masson’s trichrome.staining (P e.icle.. The.e.re.ults de.onstrate. that Se.icapoc mitigate. both ste.tosis and fibrosis in live. fibrosis *** data sugge.t that Se.icapoc inte.rupts more.than one.node.in progre.sive.fatty live. dise.se.by its anti-ste.totic and anti-fibrotic activitie., se.ving as a double.e.ge. the.ape.tic sword.

关键词： High fat die. Live. Ste.tosis Fibrosis KCa3.1 channe. Se.icapoc Inflammation

Comparison of gastrointe.tinal parasite.communitie. in ve.ve. monke.s

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Inte.rative.Zoology 2017年第6期12卷 512-520页

作者： Kim VALe.TA De.nis TWINOMUGISHA Kathle.n GODFRe. Cynthia LIU Valérie.A.M.SCHOOF Tony L.goldberg Colin A.CHAPMAN McGill School of e.vironme.t McGill UniversityMontrealQuebecCanada Make.e.e.Unive.sity Biological Fie.d Station KampalaUganda Bilingual Biology Program Department of Multidisciplinary StudiesGlendon CampusYork UniversityTorontoOntarioCanada De.artme.t of Pathobiological Scie.ce. School of Veterinary MedicineUniversity of Wisconsin-MadisonMadisonWisconsinUSA Wildlife.Conse.vation Socie.y BronxNew YorkUSA

Globally,habitat de.radation is acce.e.ating,e.pe.ially in the.*** to inte.face.habitats can incre.se.e.vironme.tal ove.lap among nonhuman primate.,pe.ple.and dome.tic animals and change.stre.s le.e.s in wildlife.le.ding to change. in the.r risk of parasite.***,the.dire.tion and conse.ue.ce. of the.e.change. are.uncle.r,since.animals may be.e.it by e.ploiting human re.ource.(e.g.,improving nutritional he.lth by e.ting nutritious crops)and de.re.sing susce.tibility to infe.tion,or inte.actions with humans may le.d to chronic stre.s and incre.se. susce.tibility to *** monke.s are.an e.ce.le.t mode. to unde.stand parasitic dise.se.transmission be.ause.of the.r tole.ance.to anthropoge.ic *** we.quantify the.gastrointe.tinal parasite. of a group of ve.ve. monke.s(Chloroce.us ae.hiops)ne.r Lake.Nabugabo,Uganda,that fre.ue.tly ove.laps with pe.ple.in the.r use.of a highly modifie. *** compare.the.parasite. found in this population to se.e. othe. site. whe.e.ve.ve. monke. gastrointe.tinal parasite. have.be.n ide.ti*** ve.ve.s of Lake.Nabugabo have.the.gre.te.t richne.s of parasite. docume.te. to *** discuss how this may re.le.t diffe.e.ce. in sampling inte.sity or diffe.e.ce. in the.type. of habitat whe.e.ve.ve. parasite. have.be.n sample..

关键词： anthropoge.ic disturbance dise.se gastrointe.tinal parasite habitat de.radation Nabugabo ve.ve. zoonotic dise.se

Re.rograde.intrare.al surge.y for lowe. pole.stone. utilizing stone.displace.e.t te.hnique.yie.ds e.ce.le.t re.ults

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Asian Journal of Urology 2023年第1期10卷 58-63页

作者： Dor Golomb Hanan goldberg Shlomi Tapie.o Yariv Stabholz Paz Lotan Abd e.halim Darawsha Rone. Holland Yaron e.rlich David Lifshitz De.artme.t of Urology Rabin Medical Center-Beilinson HospitalPetach TikvaSackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael De.artme.t of Urology State University of New York Upstate Medical UniversitySyracuseNYUSA

Obje.tive.To e.aluate.the.long-te.m stone.fre. rate.SFR)of re.rograde.intrare.al surge.y(RIRS)in the.tre.tme.t of lowe. pole.re.al calculi using only baske. re.ocation and ide.tify inde.e.de.t pre.ictors of stone.fre. ***:All conse.utive.patie.ts unde.going RIRS lowe. pole.re.al calculi at a single.highvolume.te.tiary ce.te. we.e.analyze. *** pole.stone. we.e.re.ocate. to the.uppe. pole.whe.e.lase. lithotripsy was *** patie.ts we.e.followe. up in the.clinic following the.surge.y and ye.rly *** stone.fre. status was asse.se. with a combination of an abdominal ultrasound and abdominal X-ray,or an abdominal non-contrast compute. tomography if the.stone. we.e.known to be.***:A total of 480 conse.utive.patie.ts who unde.we.t RIRS for tre.tme.t of lowe. pole.re.al calculi,be.we.n January 2012 and De.e.be. 2018,we.e.analyze. from a prospe.tive.y maintaine. database.of 3000 *** a me.ian follow-up time.of 18.6 months,the.me.n SFR was 94.8%.The.proce.ure. we.e.unsucce.sful in 26(5.4%)patie.ts due.to unre.chable.*** me.ian stone.size.of the.unre.chable.stone. was 12 mm(range.10e.0 mm).Multivariable.logistic re.re.sion analysis re.e.le. two pre.ictors of SFR for lowe. pole.stone.:a small cumulative.stone.burde.(odds ratio[OR]:0.903,95%confide.ce.inte.val[CI]:0.867e..941,pe.pe.ative.ure.e.al ste.t inse.tion(OR:0.515,95%CI:0.318e..835,pZ0.007).Conclusion:The.long-te.m SFR of RIRS for the.tre.tme.t of lowe. pole.stone. with baske. displace.e.t with appropriate.patie.t se.e.tion is high.

关键词： Ure.e.oscopy Lowe. pole.stone. Re.rograde.intrare.al surge.y Stone.fre. rate Baske.ing

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社区冠心病死亡率的变化趋势

世界核心医学期刊文摘（心脏病学分册） 2006年第6期2卷 24-25页

作者： goldberg R.J. Glatfe.te. K. Burbank- Schmidt e. 赵君 Division of Cardiovascular Me.icine Department of Medicine University of Massachusetts Medical School 55 Lake Avenue North Worcester MA 01655 United States Dr.

Background: Re.ative.y little.data are.available. particularly from the.more.ge.e.alizable.pe.spe.tive.of a population- base. inve.tigation, de.cribing re.e.t tre.ds in de.th rate. due.to coronary he.rt dise.se.CHD). The.obje.tive. of this obse.vational study we.e.to de.cribe.change. ove. a twe.ve.ye.r pe.iod(1990- 2001) in de.th rate. due.to CHD and acute.myocardial infarction(AMI) in re.ide.ts of the.Worce.te., Massachuse.ts, me.ropolitan are.(2000 ce.sus=478,000). A se.ondary study goal was to de.cribe.change. in de.th rate. attribute. to CHD ove. time.se.arate.y in me. and in wome., in pe.sons of diffe.e.t age., and according to location of de.th. Me.hods: De.th datatape. we.e.obtaine. from the.Massachuse.ts De.artme.t of Public He.lth for gre.te. Worce.te. re.ide.ts who die. ove. the.pe.iod 1990 to 2001. Re.ults: Marke. de.line. we.e.obse.ve. in the.population de.th rate.(pe. 100,000) due.to CHD(1990 de.th rate.322; 2001 de.th rate.224) and AMI(1990 de.th rate.137; 2001 de.th rate.87) in the.gre.te. Worce.te. population. De.line. in the.annual de.th rate. attribute. to CHD we.e.obse.ve. in both the.hospital(4.4% de.line. and out- of- hospital se.ting(1.6% de.line. as we.l as for patie.ts dying from AMI(annual de.line. of 4.8% and 1.9% re.pe.tive.y). Re.uctions in CHD de.th rate. ove. time.we.e.obse.ve. in me. and in wome. and in pe.sons of all age.. Conclusions: The.pre.e.t re.ults de.onstrate.e.couraging de.line. in community de.th rate. due.to CHD and AMI ove. time.and the.impact of e.olving primary and se.ondary pre.e.tion e.forts.

关键词：冠心病(CHD) 年死亡率急性心肌梗死(AMI) 不同年龄人群社区观察性研究研究资料人口普查死亡地点死亡资料