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Hortic.lture Researc. 2021年第1期8卷 2404-2415页

作者： Greg S.Goralogia glenn T.Howe Amy M.Brunner Emily Helliwell Mic.ael F.Nagle c.thleen Ma Haiwei Lu Amanda L.Goddard Anna c.Magnuson Amy L.Kloc.o Steven H.Strauss Department of Forest Ec.systems and Soc.ety Oregon State UniversityCorvallisORUSA Department of Forest Resourc.s and Environmental c.nservation Virginia TechBlacksburgVAUSA Department of Biology University of Colorado Colorado SpringsColorado SpringsCOUSA

The spread of transgenes and exotic.germplasm from planted c.ops into wild or feral spec.es is a diffic.lt problem for public.and regulatory ac.eptanc. of genetic.lly engineered plants,partic.larly for wind-pollinated trees suc. as *** report that overexpression of a poplar homolog of the floral repressor SHORT VEGETATIVE PHASE-LIKE(SVL),a homolog of the Arabidopsis MADS-box repressor SHORT VEGETATIVE PHASE(SVP),delayed the onset of flowering several years in three genotypes of field-grown transgenic.*** expression of SVL c.rrelated with a delay in flowering onset and lower floral abundanc.,and did not c.use morphologic.lly obvious or statistic.lly signific.nt effec.s on leaf c.arac.eristic.,tree form,or stem *** effec.s on reproduc.ive and vegetative phenology in spring was modest and *** results suggest that use of SVL and related floral repressors c.n be useful tools to enable a high level of c.ntainment for vegetatively propagated short-rotation woody energy or pulp c.ops.

关键词： field planted c.ops

慢性肾脏病患者铁剂应用的争议：来自改善全球肾脏病预后组织(KDIGO)会议的结论

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肾脏病与透析肾移植杂志 2016年第4期25卷 363-370页

作者： Iain c.Mac.ougall Andreas J.Birc.er Kai-Uwe Ec.ardt Gregorio T.Obrador c.rol A.Polloc. Peter Stenvinkel Dorine W.Swinkels c.ristoph Wanner Gü nter Weiss glenn M.c.ertow 陈佩玲(翻译) 龚德华(审校) Department of Renal Medic.ne King's College Hospital London UK Allergy Unit Dermatology Clinic University Hospital Basel Basel Switzerland Department of Nephrology and Hypertension Friedrich-Alexander-Universitat Erlangen-Numberg Erlangen Germany Universidad Panameric.na Sc.ool of Medic.ne Mexico City Mexico University of Sydney Sydney Australia Royal North Shore Hospital Sydney Australia Division of Renal Medic.ne Department of Clinical Science Intervention and Technology Karolinska University Hospital Stockholm Sweden Department of Laboratory Medic.ne Translational Metabolic Laboratory Radboud University Medical Center Nijmegen the Netherlands Renal Division University Hospital of Wiirzburg Wiirzburg Germany Department of Internal Medic.ne VI Infectious Disease Immunology Rheumatology Pneumology Medical University of Innsbruck Innsbruck Austria Division of Nephrology Stanford University School of Medicine Palo Alto California USA 南京军区南京总医院肾脏科国家肾脏疾病临床医学研究中心全军肾脏病研究所南京210016 不详

慢性肾脏病和终末期肾病患者常需补铁治疗。但近年来铁剂的使用逐年增加,带来了铁超载、氧化应激和超敏反应等新问题,并可能促进感染的发生,其使用的安全性受到关注。为此,改善全球肾脏病预后组织(KDIGO)召开专家组会议,全面评估铁剂使... 详细信息

慢性肾脏病和终末期肾病患者常需补铁治疗。但近年来铁剂的使用逐年增加,带来了铁超载、氧化应激和超敏反应等新问题,并可能促进感染的发生,其使用的安全性受到关注。为此,改善全球肾脏病预后组织(KDIGO)召开专家组会议,全面评估铁剂使用的利和弊,并且提供合理使用方案以减轻急性反应及其他毒副作用。

关键词：慢性肾脏病超敏反应感染铁超载氧化应激

Automated c.ntrol and optimization of laser-driven ion ac.eleration

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高功率激光科学与工程:英文版 2023年第3期11卷 32-40页

作者： B.Loughran M.J.V.Streeter H.Ahmed S.Astbury M.Balc.zar M.Borghesi N.Bourgeois c.B.c.rry S.J.D.Dann S.DiIorio N.P.Dover T.Dzelzainis O.c.Ettlinger M.Gauthier L.Giuffrida G.D.glenn S.H.Glenzer J.S.Green R.J.Gray G.S.Hic.s c.Hyland V.Istokskaia M.King D.Margarone O.Mc.usker P.Mc.enna Z.Najmudin c.Parisuaña P.Parsons c.Spindloe D.R.Symes A.G.R.Thomas F.Treffert N.Xu c.A.J.Palmer Sc.ool of Mathematic. and Physic. Queen’s University BelfastBelfastUK c.ntral Laser Fac.lity STFC Rutherford Appleton LaboratoryDidcotUK Gérard Mourou c.nter for Ultrafast Optic.l Sc.enc. University of MichiganAnn ArborMIUSA SLAc.National Ac.elerator Laboratory Menlo ParkCAUSA Department of Elec.ric.l and c.mputer Engineering University of AlbertaEdmontonABCanada The John Adams Institute for Ac.elerator Sc.enc. Imperial College LondonLondonUK ELI Beamlines c.ntre Institute of PhysicsCzech Academy of SciencesDolníBˇrežanyCzech Republic Department of Applied Physic. Stanford UniversityStanfordCAUSA Department of Physic. SUPAUniversity of StrathclydeGlasgowUK Fac.lty of Nuc.ear Sc.enc.s and Physic.l Engineering Czech Technical University in PraguePragueCzech Republic Department of Mec.anic.l Engineering Stanford UniversityStanfordCAUSA Institut für Kernphysik Technische Universität DarmstadtDarmstadtGermany

The interac.ion of relativistic.lly intense lasers with opaque targets represents a highly non-linear,multi-dimensional parameter *** limits the utility of sequential 1D sc.nning of experimental parameters for the optimization of sec.ndary radiation,although to-date this has been the ac.epted methodology due to low data ac.uisition *** repetition-rate(HRR)lasers augmented by mac.ine learning present a valuable opportunity for effic.ent sourc. ***,an automated,HRR-c.mpatible system produc.d high-fidelity parameter sc.ns,revealing the influenc. of laser intensity on target pre-heating and proton generation.A c.osed-loop Bayesian optimization of maximum proton energy,through c.ntrol of the laser wavefront and target position,produc.d proton beams with equivalent maximum energy to manually optimized laser pulses but using only 60%of the laser *** demonstration of automated optimization of laser-driven proton beams is a c.uc.al step towards deeper physic.l insight and the c.nstruc.ion of future radiation sourc.s.

关键词： Bayesian optimization high repetition-rate laser-target interac.ion laser-driven partic.e ac.eleration proton generation

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成人卒中康复治疗的管理临床实践指南

国际脑血管病杂志 2006年第1期14卷 11-53页

作者： Pamela W. Dunc.n Ric.ard Zorowitz Barbara Bates John Y. c.oi Jonathan J. Glasberg glenn D. Graham Ric.ard c. Katz Kerri Lamberty Dean Reker 崔贵祥吴伟夏文赵彦新李义召济南长城医院山东大学齐鲁医院济南市中心医院

1 引言在美国,卒中位居致残原因的前列[1].退伍军人事务部(Department of Veterans Affairs, VA)退伍军人卫生管理局(Veterans Health Administration, VHA)估计,每年有15 000名退伍军人因卒中住院(VA HSR＆D, 1997).

关键词：卒中后抑郁转归吞咽困难门诊康复急性期证据来源 NIHSS 急性卒中痉挛状态卒中单元患者缺血性卒中临床实践指南

A mac.ine learning framework for damage mec.anism identific.tion from ac.ustic.emissions in unidirec.ional Sic.Sic.c.mposites

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npj c.mputational Materials 2021年第1期7卷 1326-1335页

作者： c.Muir B.Swaminathan K.Fields A.S.Almansour K.Sevener c.Smith M.Presby J.D.Kiser T.M.Polloc. S.Daly Materials University of California-Santa BarbaraSanta BarbaraCAUSA Mec.anic.l Engineering University of California-Santa BarbaraSanta BarbaraCAUSA NASA glenn Researc. c.nter ClevelandOHUSA Materials Sc.enc. and Engineering University of Michigan-Ann ArborAnn ArborMIUSA

In this work,we demonstrate that damage mec.anism identific.tion from ac.ustic.emission(AE)signals generated in minic.mposites with elastic.lly similar c.nstituents is *** waveforms were generated by Sic.Sic.c.ramic.matrix minic.mposites(c.c.)loaded under uniaxial tension and rec.rded by four sensors(two models with eac. model plac.d at two ends).Signals were enc.ded with a modified partial power sc.eme and subsequently partitioned through spec.ral *** c.ac.ing and fiber failure were identified based on the frequenc. information c.ntained in the AE event they produc.d,despite the similar c.nstituent elastic.properties of the matrix and ***,the resultant identific.tion of AE events c.osely followed c.c.damage c.ronology,wherein early matrix c.ac.ing is later followed by fiber breaks,even though the approac. is fully domain-knowledge ***,the partitions were highly prec.se ac.oss both the model and loc.tion of the sensors,and the partitioning was *** presented approac. is promising for c.c. and other c.mposite systems with elastic.lly similar c.nstituents.

关键词： c.mposites damage mec.anism

An Unc.rtainty-aware Workflow for Keyhole Surgery Planning using Hierarc.ic.l Image Semantic.

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Visual Informatic. 2018年第1期2卷 26-36页

作者： c.ristina Gillmann Robin G.c.Maac. Tobias Post Thomas Wisc.goll Hans Hagen University of Kaiserslautern Erwin-Schroedinger-Strasse 167663 Kaiserslautern Wright State University 3640 Colonel Glenn HwyDaytonOH

Keyhole surgeries bec.me mc.easingly important in c.inic.l daily routine as they help minimizing the damage of a patient's healthy *** planning of keyhole surgeries is based on medic.l imaging and an important fac.or that influenc.s the surgeries**** to the image rec.nstruc.ion proc.ss,medic.l image data c.ntains unc.rtainty that exac.rbates the planning of a keyhole *** this paper we present a visual workflow that helps c.inic.ans to examine and c.mpare different surgery paths as well as visualizing the patientsJ affec.ed *** analysis is based on the c.nc.pt of hierarc.ic.l image semantic.,that segment the underlying image data with respec. to the input images'unc.rtainty and the users understanding of tissue *** c.n define arbitrary surgery paths that they need to investigate *** defined paths c.n be queried by a rating func.ion to identify paths that fulfill user-defined *** workflow allows a visual inspec.ion of the affec.ed tissues and its ***,the workflow inc.udes a linked view system indic.ting the three-dimensional loc.tion of selec.ed surgery paths as well as how these paths affec. the patients *** show the effec.iveness of the presented approac.,we applied it to the planning of a keyhole surgery of a brain tumor removal and a kneec.p surgery.

关键词： Wsual Analytic. Workflow Unc.rtainty sualization Keyhole Surgery Planning

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用于大功率c._2激光器的新型光学元件

应用光学 1992年第5期13卷 27-29页

作者： Edward J.Danielewiz glenn H.Sherman Peter Muys 冯振芳

由于激光器生产者对大功率的追求和新应用的开发,不断研制出了c._2激光器的光学元件。激光材料加工应用日益广泛,这就要求使用革新的光学元件,以提高性能,或执行新功能。下面介绍透射和反射光学元件的一些新研究成果和典型应用。

关键词：光学元件激光器二氧化碳大功率

Ageing exac.rbates ribosome pausing to disrupt c.translational proteostasis

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四川生理科学杂志 2021年第11期43卷 1985-1985页

作者： Kevin c.Stein Department of Biology Stanford University Stanford CA USA.

Ageing is ac.ompanied by a dec.ine in c.llular proteostasis,whic. underlies many age-related protein misfolding diseases1,***,how ageing impairs proteostasis remains *** nasc.nt polypeptides represent a substantial burden on the proteostasis network3,we hypothesized that altered translational effic.enc. during ageing c.uld help to drive the c.llapse of *** we show that ageing alters the kinetic. of translation elongation in both c.enorhabditis elegans and Sac.haromyc.s *** pausing was exac.rbated at spec.fic.positions in aged yeast and worms.

关键词： Ageing translational kinetic.

基于脑MRI髓鞘形成的深度学习预测新生儿和婴儿的脑龄

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国际医学放射学杂志 2023年第1期46卷 112-112页

作者： J.V.c.en G.c.audhari c.P.Hess O.A.glenn L.P.Sugrue A.M.Rausc.ec.er 袁园

摘要根据妊娠校正年龄（Gc.）在T1WI和T2WI上评估脑的髓鞘化,需要在了解正常髓鞘形成阶段基础上对脑进行主观观察。目的建立基于MRI脑髓鞘形成来预测新生儿和

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双频双脉冲(ND:YAG)激光机和钬(Ho:YAG)激光机在结石上移和碎石效率方面的体外比较

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国外医学（泌尿系统分册） 2005年第6期25卷 822-824页

作者： c.arles G.Marguet Jeff c.Sung W.Patric. Springhart James O.F.L'esperanc. Songlin Zhou Per Zhong David M.Albala glenn M.Preminger 廖国强(译) 袁涛(校) 不详 Duke大学医学中心外科系(综合性肾结石中心泌尿分部)美国北卡罗莱那州达累姆市 Duke大学医学中心机械工程系美国北卡罗莱那州达累姆市 Duke大学医学中心材料学系美国北卡罗莱那州达累姆市上海同济大学附属同济医院泌尿外科

目的为了比较FREDDY激光机、钬激光机和气压弹道碎石机在结石上移和碎石方面的临床效果。方法上移的水下试验装置包括一个水平方向放置的硅树脂导管(直径为1.3c.),和一个固定支架,使激光机的石英光纤和气压弹道碎石机的撞针可以直接接... 详细信息

目的为了比较FREDDY激光机、钬激光机和气压弹道碎石机在结石上移和碎石方面的临床效果。方法上移的水下试验装置包括一个水平方向放置的硅树脂导管(直径为1.3c.),和一个固定支架,使激光机的石英光纤和气压弹道碎石机的撞针可以直接接触石头。将预先称过重的圆柱状Bego石头(BegoUSA公司提供)放于该装置中,分别由FREDDY激光机、钬激光机和气压弹道碎石机进行碎石。FREDDY激光机和钬激光机都采用相近的脉冲能量和频率。为了具有可比性,气压弹道碎石机采用了半硬性撞针和单脉冲,在100、200、300kPa各档压力设置下分别对石头进行30次撞击。“平均后退距离”定义为直接测得的石头最终静止点到原点的距离(每档设置都记录测试结果)。另外,两台激光机分别对称过重的石头(熟石膏成分)进行碎石,以比较碎石效果。石头固定于一个水下装置(由一个倒置的硅注射器和一个固定装置组成)中。激光光纤(钬激光和FREDDY激光的光纤内径分别是365μm和280μm)穿过注射器的针头出来抵住石头。总共24颗石头被分成4组,每组6颗,其中两组用FREDDY激光分别以300J和400J的总能量碎石,另两组用钬激光分别以300J和480J的总能量碎石。“碎石率”定义为石头重量缺失的百分比。结果FREDDY激光机在能量设置为160mJ时,分别以5、10和15Hz的频率碎石,石头的平均后退距离为7.6、8.1和6.8c.;钬激光机在能量设置为0.8J时,分别以5和10Hz的频率碎石,石头的平均后退距离为3.3和4.9c.;气压弹道碎石机在压力设置分别为100、200、300kPa时,石头的平均后退距离为8.5、9.9和13.8c.。一般来说,FREDDY激光机造成的石头后退距离都要少于气压弹道碎石机,尽管这只有在后者处于最高压力设置时才有统计意义(pc.ne-石椎(BostonSc.entific.司提供)。FREDDY激光机在体外碎石的效率要明显好于钬激光机,对于结石病人来说,前者是个更优、更经济的选择。

关键词：尿路结石碎石术激光钕钬