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A network of sex and competition： The promiscuous mating system of an invasive weevil

Current Zoology 2015年第1期61卷 85-97页

作者： Alberto Francesco INGHILESI giuseppe MAZZA Rita CERVO Alessandro CINI Department of Biology University of Florence Via Romana 17 50125 Florence Italy Agricultural Research Council Research Centre for Agrobiology and Pedology via Lanciola 12/A Cascine del Riccio 50125 Florence Italy Department of Biology University of Florence Via Madonna del Piano 6 50019 Sesto Fiorentino Florence Italy Corpo Forestale dello Stato Centro Nazionale Biodiversit~t Forestale "Bosco Fontana"Via C. Ederle 16/a 37100 Verona Italy

Invasive alien pest insect species represent a major threat for agriculture and biodiversity. Because chemical treatments employed to contrast such pests elicit serious environmental and human health problems, a great effort is currently directed to develop long term and environmentally friendly biological control strategies. However, the successful application of some promising techniques, such as the Sterile Insect Technique （SIT）, requires a deep knowledge of the pest basic biology. Here, we argue that understanding pest sexual biology using a social network approach can significantly improve the performance of con- trol strategies. For example, SIT may benefit from understanding how individuals interact and how males accede to reproduction, in order to target the most reproductively active and polygamic males. In this paper we studied the socio-sexual networks of the Asian red palm weevil （RPW） Rhynchophorusferrugineus, a worldwide invader which is causing heavy economic impacts on several palm species. We found that the RPW has a highly promiscuous mating system, characterized by forced interruptions of pair copulations by additional males. The social network is highly non-random nor regular： few males almost monopolize repro- duction, behaving as key-players in the network of matings. Additionally, males have a stable pattern of sexual behaviour over time. We use RPW social network as a case study to direct the development of management techniques such as SIT strategy [Current Zoology 61 （1）： 85-97, 2015].

关键词： Social network analysis Pest management Mating system Reproductive skew Alien pest Rhynchophorusferrugineus

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Lithium:from mood stabilizer to putative cognitive enhancer

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Neural Regeneration Research 2016年第8期11卷 1234-1235页

作者： Adele Quartini Angela Iannitelli giuseppe Bersani Department of Medical-Surgical Sciences and Biotechnologies Faculty of Pharmacy and Medicine-"Sapienza" University of RomeDSM ASL/LT-Unit of Psychiatry"A.Fiorini" Hospital

The monovalent cation lithium,whose introduction in psychiatry dates back at the end of the 1940s,remains the first-line agent in the management of patients with bipolar disorder（BD）.It is effective in the treatment of moderate-to-severe acute mania,prophylactic for recurrent manic and depressive episodes,and reduces the risk of suicide.

关键词： lithium stabilizer enhancer mania bipolar moderate neurotrophic putative boost cortex

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Hepatitis B virus recurrence after liver transplantation: An old tale or a clear and present danger?

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World Journal of Gastroenterology 2020年第18期26卷 2166-2176页

作者： Ilaria Lenci Martina Milana giuseppe Grassi Tommaso M Manzia Carlo Gazia giuseppe Tisone Roberta Angelico Leonardo Baiocchi Hepatology and Liver Transplant Unit University of Tor VergataRome 00133Italy Hepato-Pancreato-Biliary and Transplant Department of SurgeryUniversity of Rome Tor VergataRome 00133Italy

Hepatitis B virus(HBV) recurrence after liver transplantation(LT) has been described more than 50 years ago. Similarly, to other clinical conditions, in which impairment of host immune defense favors viral replication, early reports described in details recurrence and reactivation of HBV in liver transplant recipients. The evidence of a possible, severe, clinical evolution of HBV reappearance in a significant percentage of these patients, allowed to consider,for some years, HBV positivity a contraindication for LT. Moving from the old to the new millennium this picture has changed dramatically. Several studies contributed to establish efficient prophylactic protocols for HBV recurrence and with the advent of more potent anti-viral drugs an increased control of infection was achieved in transplanted patients as well as in the general immunecompetent HBV population. Success obtained in the last decade led some authors to the conclusion that HBV is now to consider just as a "mere nuisance".However, with regard to HBV and LT, outstanding issues are still on the table:(1)A standard HBV prophylaxis protocol after transplant has not yet been clearly defined;(2) The evidence of HBV resistant strains to the most potent antiviral agents is claiming for a new generation of drugs;and(3) The possibility of prophylaxis withdrawal in some patients has been demonstrated, but reliable methods for their selection are still lacking. The evolution of LT for HBV is examined in detail in this review together with the description of the strategies adopted to prevent HBV recurrence and their pros and cons.

关键词： Liver transplant Hepatitis B virus Viral recurrence Prophylaxis Minimization Antiviral drug

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Use of generated artificial road profiles in road roughness evaluation

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Journal of Modern Transportation 2017年第1期25卷 24-33页

作者： giuseppe Loprencipe Pablo Zoccali Department of Civil Building and Environmental EngineeringSapienza University of RomeVia Eudossiana1800184 RomeItaly

In the evaluation of road roughness and its effects on vehicles response in terms of ride quality, loads induced on pavement, drivers＇ comfort, etc., it is very common to generate road profles based on the equation provided by ISO 8608 standard, according to which it is possible to group road surface profiles into eight different classes. However, real profiles are significantly different from the artificial ones because of the non-stationary fea- ture of the first ones and the not full capability of the ISO 8608 equation to correctly describe the frequency content of real road profiles. In this paper, the international roughness index, the frequency-weighted vertical acceleration awz according to ISO 2631, and the dynamic load index are applied both on artificial and real profiles, highlighting the different results obtained. The analysis carried out in this work has highlighted some limitation of the ISO 8608 approach in the description of performance and conditions of real pavement profiles. Furthermore, the different sensitivity of the various indices to the fitted power spectral density parameters is shown, which should be taken into account when performing analysis using artificial profiles.

关键词： Ride quality International roughness indexDynamic load index Road surface irregularities - ISO2631 ISO 8608 Real road profiles Artificial roadprofiles

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Measurement methods and analysis tools for rail irregularities:a case study for urban tram track

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Journal of Modern Transportation 2015年第2期23卷 137-147页

作者： Laura Chiacchiari giuseppe Loprencipe Dipartimento di Ingegneria Civile e Ambientale SapienzaUniversitàdi Roma

Rail irregularities, in particular for urban rail- way infrastructures, are one of the main causes for the generation of noise and vibrations. In addition, repetitive loading may also lead to decay of the structural elements of the rolling stock. This further causes an increase in main- tenance costs and reduction of service life. Monitoring these defects on a periodic basis enables the network rail managers to apply proactive measures to limit further damage. This paper discusses the measurement methods for rail corrugation with particular regard to the analysis tools for evaluating the thresholds of acceptability in re- lation to the tramway Italian transport system. Further- more, a method of analysis has been proposed： an application of the methodology used for treating road profiles has been also utilized for the data processing of rail profilometric data.

关键词： Rail corrugation Noise disturbance Measurement methods Continuous measurement Dataprocessing algorithm Wavebands filtering

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Comparison of Cardiorespiratory and Metabolic Responses Between Kettlebell Half Marathon and Treadmill Running at the Same Average Oxygen Consumption: A Case Study

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Journal of Science in Sport and Exercise 2021年第4期3卷 379-384页

作者： Davide Greco Luca Calanni giuseppe Cerullo Massimo Negro giuseppe D’Antona CRIAMS-Sport Medicine Centre University of PaviaVogheraItaly Department of Movement Sciences and Wellbeing Parthenope UniversityNaplesItaly Department of Public Health Experimental and Forensic Medicine and Sport Medicine Centre VogheraUniversity of Paviavia Foscolo1327058 VogheraItaly

Purposes In kettlebell sport(KS)half marathon,the lift of the kettlebell is required for the highest number of repetitions in 30 *** data are available on cardiorespiratory and metabolic responses during this exercise *** aim of the study was to evaluate cardiopulmonary and metabolic responses to KS half marathon compared to 30 min treadmill running,chosen as a reference paradigm of aerobic exercise,at the same average oxygen consumption(VO_(2)).Methods A male elite KS athlete was enrolled in two trials separated by 7 days of *** the first trial,one-hand long-cycle KS exercise with a 1/3 body weight kettlebell was performed for 30 min(kettlebell half marathon,KT);in the second trial,30 min treadmill running(TR)was performed at the same average VO2 measured in the first trial(speed 9-10 km/h at 1°uphill inclination).Metabolic and cardiopulmonary assessments[respiratory exchange ratio(RER),tidal volume(TV),breathing frequency(f),minute ventilation(VE)],blood lactate(BL)kinetics,heart rate(HR),and blood pressure(BP)were measured in both experimental *** The average VO_(2) was 33.3 mL/min/kg in KT and 30.6 mL/min/kg in *** subject achieved RER_(peak) 1.17,RER_(mean) 0.98,HR_(peak) 172 bpm(94% HR_(max)),HR_(mean) 86% of HR_(max),BP_(peak) 220/100 mmHg in KT,BL_(peak) 7.2 mmol/L(during trial)in KT and RER_(peak) 1.13,RER_(mean) 0.89,HR_(peak) 142 bpm(78%HR_(max)),HR_(mean) 70% of HR_(max),BP_(peak) 160/80 mmHg,BL_(peak) 3.5 mmol/L(4 min after trial)mmol/L in *** Data indicate that a KS half marathon determines much higher cardiopulmonary and metabolic responses to treadmill running performed at similar VO_(2).

关键词： Kettlebell sport Blood lactate Blood pressure Heart rate Oxygen consumption

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Isoxazolone Reactivity Explained by Computed Electronic Structure Analysis

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Chinese Journal of Chemistry 2020年第2期38卷 163-168页

作者： Giovanni Bella Antonio Santoro Massimiliano Cordaro Francesco Nicolò giuseppe Bruno Department of Chemical BiologicalPharmaceutical and Environmental SciencesUniversity of MessinaViale F.Stagno d'Alcontres 3198166 MessinaItaly

Summary of main observation and conclusion lsoxazol(2H)-5-one was chosen as a model molecule to study the structural features(a,p angles and carbonyl bond length)regarding lactone moiety in the isoxazolone species by computational *** method with B3LYP 6-311++G(2df,2p)basis set was used to carry out the optimization on a series(A and B families)of isoxazolones suitably substituted on double bond.

关键词： calculation. moiety substituted

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Numerical Simulation of Compressible Vortical Flows Using a ConservativeUnstructured-GridAdaptive Scheme

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Communications in Computational Physics 2012年第8期12卷 866-884页

作者： giuseppe Forestieri Alberto Guardone Dario Isola Filippo Marulli and giuseppe Quaranta Dipartimento di Ingegneria Aerospaziale Politecnico di MilanoVia La Masa3420156 MilanoItaly

A two-dimensional numerical scheme for the compressible Euler equations is presented and applied here to the simulation of exemplary compressible vortical *** proposed approach allows to perform computations on unstructured moving grids with adaptation,which is required to capture complex features of the *** adaptation is driven by suitable error indicators based on theMach number and by element-quality constraints as *** the new time level,the computational grid is obtained by a suitable combination of grid smoothing,edge-swapping,grid refinement and *** grid modifications-including topology modification due to edge-swapping or the insertion/deletion of a new grid node-are interpreted at the flow solver level as continuous(in time)deformations of suitably-defined node-centered finite *** solution over the new grid is obtained without explicitly resorting to interpolation techniques,since the definition of suitable interface velocities allows one to determine the new solution by simple integration of the Arbitrary Lagrangian-Eulerian formulation of the flow *** simulations of the steady oblique-shock problem,of the steady transonic flow and of the start-up unsteady flow around the NACA 0012 airfoil are presented to assess the scheme capabilities to describe these flows accurately.

关键词： Moving grid method conservative interpolation

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Post-operative imaging in liver transplantation: State-of-the-art and future perspectives

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World Journal of Gastroenterology 2014年第20期20卷 6180-6200页

作者： Rossano Girometti giuseppe Como Massimo Bazzocchi Chiara Zuiani Department of Medical and Biological Sciences Institute of Diagnostic Radiology University of Udine 33100 Udine Italy

Orthotopic liver transplantation(OLT)represents a major treatment for end-stage chronic liver disease,as well as selected cases of hepatocellular carcinoma and acute liver *** ever-increasing development of imaging modalities significantly contributed,over the last decades,to the management of recipients both in the pre-operative and post-operative period,thus impacting on graft and patients *** properly used,imaging modalities such as ultrasound,multidetector computed tomography,magnetic resonance imaging(MRI)and procedures of direct cholangiography are capable to provide rapid and reliable recognition and treatment of vascular and biliary complications occurring after *** defined is the role for imaging in assessing primary graft dysfunction(including rejection)or chronic allograft disease after OLT,e.g.,hepatitis C virus(HCV)*** paper:(1)describes specific characteristic of the above imaging modalities and the rationale for their use in clinical practice;(2)illustrates main imaging findings related to post-OLTcomplications in adult patients;and(3)reviews future perspectives emerging in the surveillance of recipients with HCV recurrence,with special emphasis on MRI.

关键词： Orthotopic liver transplantation Ultrasound Computed tomography Magnetic resonance imaging T-tube cholangiography Endoscopic retrograde cholangiography Percutaneous transhepatic cholangiography Orthotopic liver transplantation complications Human C virus recurrence

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The differential benefit of laparoscopic over open minor liver resection for lesions situated in the anterolateral or posterosuperior segments

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Hepatobiliary Surgery and Nutrition 2024年第4期13卷 604-615,I0015-I0021页

作者： Jasper P.Sijberden Guido Fiorentini Jacopo Lanari Davit Aghayan Daniel Osei-Bordom Nadia Russolillo Arjun Takhar Andrea Benedetti Cacciaguerra Santi Lopez-Ben Mathieu D’Hondt Felice Giuliante David Fuks Fernando Rotellar Andrea Ruzzenente Adnan Alseidi Mikhail Efanov Burak Görgec giuseppe Zimmitti Enrico Gringeri Federica Cipriani Åsmund Avdem Fretland Ravi Marudanayagam Marco Vivarelli John N.Primrose Alessandro Ferrero Robert P.Sutcliffe Bjørn Edwin Umberto Cillo Marc G.Besselink Mohammad Abu Hilal Luca A.Aldrighetti Department of Surgery Fondazione Poliambulanza Istituto OspedalieroBresciaItaly Amsterdam UMC location University of Amsterdam Department of SurgeryAmsterdamthe Netherlands Cancer Center Amsterdam Amsterdamthe Netherlands Hepatobiliary Surgery Division IRCCS San Raffaele HospitalMilanItaly Department of Surgical Oncological and Gastroenterological SciencesGeneral Surgery 2Hepatobiliary Surgery and Liver TransplantationPadua University HospitalPaduaItaly The Intervention Centre and Department of HPB Surgery Oslo University Hospital and Institute of Clinical MedicineUniversity of OsloOsloNorway Department of Surgery Ringerike HospitalVestre Viken Hospital TrustDrammenNorway Liver Unit Queen Elizabeth HospitalBirminghamUK Department of General and Oncological Surgery Umberto I Mauriziano HospitalLargo TuratiTurinItaly Department of Surgery University Hospital Southampton NHS Foundation TrustSouthamptonUK Hepatobiliary and Abdominal Transplantation Surgery Department of Experimental and Clinical MedicineRiuniti HospitalPolytechnic University of MarcheAnconaItaly Servei de Cirurgia General i Digestiva Hospital Doctor Josep Trueta de GironaGironaCataloniaSpain Department of Digestive and Hepatobiliary/Pancreatic Surgery Groeninge HospitalKortrijkBelgium Chirurgia Epatobiliare UniversitàCattolica del Sacro Cuore-IRCCSRomeItaly Department of Digestive Oncologic and Metabolic SurgeryInstitut Mutualiste MontsourisUniversitéParis DescartesParisFrance HPB and Liver Transplantation Unit Department of SurgeryUniversity ClinicUniversidad de NavarraNavarraSpain Institute of Health Research of Navarra(IdisNA) PamplonaSpain Department of Surgery University of VeronaVeronaItaly Department of Surgery Virginia Mason Medical CenterSeattleWAUSA Department of Surgery University of California San FranciscoSan FranciscoCAUSA Department of Hepato-Pancreato-Biliary Surgery Moscow Clinical Research CentreMoscowRussia

Background:It is well known that laparoscopic liver surgery can offer advantages over open liver surgery in selected ***,what type of procedures can benefit most from a laparoscopic approach has been investigated poorly thus *** aim of this study is thus to define the extent of advantages of laparoscopic over open liver surgery for lesions in the anterolateral(AL)and posterosuperior(PS)***:In this international multicentre retrospective cohort study,laparoscopic and open minor liver resections for lesions in the AL and PS segments were compared after propensity score *** differential benefit of laparoscopy over open liver surgery,calculated using bootstrap sampling,was compared between AL and PS resections and expressed as a Delta of the ***:After matching,3,040 AL and 2,336 PS resections were compared,encompassing open and laparoscopic procedures in a 1:1 *** and PS laparoscopic liver resections were more advantageous in comparison to open in terms of blood loss,transfusion rate,complications,and length of ***,AL resections benefitted more from laparoscopy than PS in terms of overall and severe complications(D-difference were 4.8%,P=0.046 and 3%,P=0.046)and blood loss(D-difference was 195 mL,P<0.001).Similar results were observed in the subset for high-volume centres,while in recent years no significant differences were found in the differential benefit between AL and PS ***:The advantage of laparoscopic over open liver surgery is greater in the AL segments than in the PS segments.

关键词： Liver neoplasms hepatectomy laparoscopic liver resection open liver resection

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