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A review on biomedical and dental applications of cerium oxide nanoparticles——Unearthing the potential of this rare earth metal

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Journal of Rare Earths 2023年第11期41卷 1645-1661,I0001页

作者： Lalitha S Jairam Akshatha chandrashekar T.Niranjana Prabhu Sunil Babu Kotha M.S.girish Indira Mysuru Devraj M.Dhanya Shri K.Prashantha Department of Pediatric and Preventive Dentistry Faculty of Dental SciencesM.S.Ramaiah University of Applied SciencesNew BEL RoadMSR NagarBangalore560054India Department of chemistry Faculty of Mathematical and Physical SciencesM.S.Ramaiah University of Applied SciencesNo.470-PIV PhasePeenya Industrial AreaBangalore560058India Department of Preventive Dentistry Pediatric Dentistry DivisionCollege of DentistryRiyadh Elm UniversityRiyadhKingdom of Saudi Arabia Department of Pediatric and Preventive Dentistry JSS Dental College&HospitalJSS Academy of Higher Education&ResearchMysuruIndia Center for Research and Innovation Adichunchanagiri School of Natural SciencesAdichunchanagiri UniversityBGSITB.G.Nagara571448India

Nanotechnology deals with particles ranging from 1 to 100 nm in size called as *** nano particles exhibit unique properties which find an application in many industries and medical fields.A growing body of evidence points out the newer developing technologies adopted in the field of medicine in terms of target therapies,imaging systems,drug deliveries,*** through the incorporation of *** oxide nanoparticles have gained attention in the last decade due to exceptional properties such as redox activity,biofilm inhibition,antibacterial activity,anti-inflammatory activity,*** method of synthesis of cerium oxide nanoparticles plays a pivotal role in its *** exhibits redox properties and catalytic activity and thus has found its use in biomedical *** are incorporated into dental materials such as restorative cements/sealants,adhesives,and denture systems to improve their *** the various metal oxide nanoparticles,ce rium oxide nanoparticles(CeO_(2)NPs)are known to exhibit lower toxicity to mammalian cells and possess unique antibacterial *** addition,they exhibit potent properties such as antitumor,antiinflammatory,antibacterial activities,and functions as an ***_(2)NPs have excellent scavenging properties for reactive oxygen species,which is why they are being considered for therapeutic *** this review,various methods of synthesis of CeO_(2)NPs are *** factors that determine the particle size and morphology of these materials are important for biomedical and dental *** is given to preparation methods and variables such as calcination temperature,which have a profound effect on particle size and *** article also presents various applications of CeO_(2)NPs in the biomedical and dental fields.

关键词： Cerium oxide nanoparticles Synthesis Antibacterial activity Biomedical applications Dental applications Rare earths

^(57)Fe M?ssbauer spectroscopy study of organic rich sediments(source rocks) from test well CT-1, chinnewala structure of Jaisalmer basin,India

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Geoscience Frontiers 2016年第5期7卷 793-798页

作者： R.P.Tripathi Beena Bhatia R.Sharma K.R.Patel S.S.Meena girish Ganwani S.C.Mathur Department of Physics Jai Narain Vyas University Jodhpur 342 005 India Department of Geology Jai Narain Vyas University Jodhpur 342 005 India

^57Fe Mossbauer spectroscopic study was carried out on the organic rich sedimentary samples collected at different depth intervals from newly drilled test well chinnewala Tibba-1（CT-1） located in Jaisalmer Petroliferous basin India. It is found that iron is mainly distributed in high spin Fe^3＋and Fe^2＋ state in clay minerals. The plot of Fe^2＋/（Fe^2＋＋ Fe^3＋） indicates the presence of poor redox conditions in the *** obtained are also compared with those already reported in the literature. This comparison shows that there may exist a correlation between prospecting of the basin, the redox environment in sediments and the nature of iron bearing minerals distributed in the sedimentary sequence.

关键词： Jaisalmer petroliferous basin chinnewala Tibba structure ^57Fe Mossbauer spectroscopic study Source rocks Hydrocarbon prospecting

中国玩具企业在印度市场的营销策略研究——以A公司为例

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中国玩具企业在印度市场的营销策略研究——以A公司为例

作者： KRISHNAN girish 南昌大学

学位级别：硕士

中国自1978年改革开放以来,其经济迅猛发展。同时,贸易方式也发生了巨大的转变,由最初的“三来一补”为特征的加工贸易逐步转变为开发自有品牌的贸易模式。不得不承认,中国改革开放30多年来,其在各方面都已经取得了令世人瞩目的成就。当... 详细信息

中国自1978年改革开放以来,其经济迅猛发展。同时,贸易方式也发生了巨大的转变,由最初的“三来一补”为特征的加工贸易逐步转变为开发自有品牌的贸易模式。不得不承认,中国改革开放30多年来,其在各方面都已经取得了令世人瞩目的成就。当前,全球经济整体下滑,尤其是欧美国家需求疲软和中国国内需求不足的情况下,中国以出口为主的外向型经济的发展受到了严重的制约。同第三世界国家如南亚地区发展经贸关系将会是中国转变外贸结构的必然选择。中国国家总理李克强在2013年5月访问印度期间,双方提议建设孟中印缅经济走廊,以此来加强中印两个大市场的贸易伙伴关系。同年中国国家主席习近平提出“一带一路”的战略构想,为进一步深化中国与友好国家的合作提供了契机。一方面,中国改革玩具行业既是世界玩具生产大国同时又是出口大国。但是另一方面,中国玩具行业还存在着很多的困难,比较突出的如面临着如何更好地拓宽国际市场的问题。印度经济近些年飞速发展,人们的生活水平也在不断提高,同时居住环境和办公条件日益改善,市场对玩具的需求量也不断扩大,为中国玩具产品提供了良好的海外拓展空间。在此背景下,本文首先对营销策略理论、现代营销组合理论、国际市场营销理论等相关理论和国内外众多学者研究成果的梳理,为后文研究提供理论和研究基础;其次,分析了印度玩具市场需求特点、玩具营销策略制定的影响因素,建立中国玩具产品印度市场营销策略制定影响因素体系;第三,以A玩具生产企业为例,通过SWOT分析法深入剖析其开拓印度市场的必要性、可行性,并提出相关营销策略;最后,对中国玩具企业如何进一步拓展印度市场提出了一些具有针对性的策略,以期对相关行业企业实施海外营销提供借鉴。

关键词：中国玩具企业印度市场营销策略 SWOT分析

Entropy generation minimization in the Carreau nanofluid flow over a convectively heated inclined plate with quadratic thermal radiation and chemical reaction:A Stefan blowing application

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Propulsion and Power Research 2024年第2期13卷 233-244页

作者： B.Lavanya J.girish Kumar M.Jayachandra Babu C.S.K.Raju Bander Almutairi Nehad Ali Shah Department of Mathematics Manipal Institute of TechnologyManipal Academy of Higher EducationManipalKarnataka 576104India Department of Mathematics S.V.A Government CollegeSrikalahasti 517644India Department of Mathematics GITAM School of Science(GSS)GITAMBangaloreKarnatakaIndia Department of Mathematics College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia Department of Mechanical Engineering Sejong UniversitySeoul 05006South Korea

Entropy analysis can help to identify the sources of entropy generation in a heat transfer process more accurately than other methods,such as energy efficiency *** is because entropy analysis takes into account the quality of energy as well as its ***-nofluids have already been shown to have superior heat transfer characteristics compared to *** blowing can further enhance the heat transfer capabilities of nano-fluids by increasing the massflux and turbulence at the *** can be beneficial in a wide range of applications,such as heat exchangers,electronic cooling,and solar energy *** convective boundary condition accounts for heat transfer effects,influencing temperature distribution and the thermal boundary *** on the direction of heat transfer,the convective boundary condition can induce cooling or heating effects on the inclined *** has practical implications for various engineering applications,such as the cooling of electronic devices or heating in industrial *** nanofluids have a wide range of potential applications in heat transfer,energy storage,drug delivery,and food *** research investigates how the presence of Stefan blowing affects the properties of Carreau nanofluid flow across a convectively heated tilted *** and mass transport phenomena are studied using quadratic thermal radiation and chemical reaction *** mathematical model for this work is based on the Buongiorno *** governing equations are converted into a system of ordinary differential equations and then solved using the bvp4c *** parameters such as the mass transfer rate can be visualized using bar *** study’s primary findings are that when the Weissenberg number increases,the velocity rises and the concentration profile declines due to Brownian *** is discovered that,when 0.5≤γ≤3(the inverse porosity parameter),the friction factor declines by 0

关键词： Thermal radiation BVP4C Stefan blowing Biot number Brownian motion Irreversibilit

Giant idiopathic renal arteriovenous fistula managed by coils and amplatzer device:Case report and literature review

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World Journal of Clinical Cases 2016年第11期4卷 364-368页

作者： Prashant Nagpal girish Bathla Sachin S Saboo Ashish Khandelwal Abhishek Goyal Frank J Rybicki Michael L Steigner Department of Radiology University of Iowa Hospitals and Clinics Department of Radiology Brigham and Women’s HospitalHarvard Medical School Department of Radiology Cardiothoracic ImagingUT Southwestern Medical Center Department of Internal Medicine Westchester Medical CenterNew York Medical College

An idiopathic renal arteriovenous(AV) fistula is a rare malformation of the kidney that may present insidiously with heart failure or *** treatment may be challenging due to large fistula size that may limit endovascular *** authors report a case of an 85-year-old Caucasian woman who presented with acute heart failure and was found to have a right renal AV *** she had no prior history of renal intervention or trauma,a diagnosis of idiopathic renal AV fistula was *** was managed by endoluminal occlusion using multiple stainless steel coils and Amplatzer vascular plug II *** follow-up computed tomography showed complete occlusion of the *** report highlights the late presentation of this rare disease and presents the utility of the combination of coils and Amplatzer device for management of a large *** also reiterates that even if large,these fistulas can be managed by endovascular occlusion.

关键词： Heart failure Idiopathic Arteriovenous fistula Endovascular management Amplatzer device

Understanding the role of endothelial cells in brain tumor formation and metastasis: a proposition to be explored for better therapy

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Journal of the National Cancer Center 2023年第3期3卷 222-235页

作者： Tejas girish Agnihotri Sagar Salave Tanuja Shinde Induri Srikanth Vijay Gyanani Jeffrey C.Haley Aakanchha Jain Department of Pharmaceutics National Institute of Pharmaceutical Education and Research(NIPER)-AhmedabadPalajIndia Long Acting Drug Delivery Celanese CorporationIrvingUnited States

Glioblastoma is one of the most devastating central nervous system *** a highly vascular brain tumor,it is distinguished by aberrant vessel *** lends credence to the idea that endothelial cells(ECs)linked with glioblastoma vary fundamentally from ECs seen in the healthy human *** effectively design an antiangiogenic treatment,it is crucial to identify the functional and phenotypic characteristics of tumor-associated *** ECs associated with glioblastoma are less prone to apoptosis than control cells and are resistant to cytotoxic ***,ECs associated with glioblastoma migrate more quickly than control ECs and naturally produce large amounts of growth factors such as endothelin-1,interleukin-8,and vascular endothelial growth factor(VEGF).For designing innovative antiangiogenic drugs that particularly target tumor-related ECs in gliomas,it is critical to comprehend these distinctive features of ECs associated with *** review discusses the process of angiogenesis,other factors involved in the genesis of tumors,and the possibility of ECs as a potential target in combating *** also sheds light on the association of tumor microenvironment and ECs with *** review,thus gives us the hope that neuro endothelial targeting with growth factors and angiogenesis regulators combined with gene therapy would open up new doorways and change our traditional perspective of treating cancer.

关键词： Angiogenesis Gene therapy Growth factors Metastasis Neuro endothelial cells

Comparative analysis of real-world data of frequent treatment sequences in metastatic prostate cancer

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Current Urology 2024年第2期18卷 104-109页

作者： Jiten Jaipuria Ishleen Kaur Mohammad Najmud Doja Tanvir Ahmad Amitabh Singh Sudhir Kumar Rawal Vineet Talwar girish Sharma Uro-oncology division Rajiv Gandhi Cancer Institute and Research CentreNew DelhiIndia Amity Centre for Cancer Epidemiology and Cancer Research Amity Institute of BiotechnologyAmity UniversityNoidaIndia School of Engineering and Technology Vivekananda Institute of Professional Studies–Technical CampusNew DelhiIndia Department of Computer Engineering Jamia Millia IslamiaNew DelhiIndia Indian Institute of Information Technology SonepatIndia Department of MedicalOncology Rajiv Gandhi Cancer Institute and Research CentreNew DelhiIndia

Background:The incidence of prostate cancer is increasing worldwide.A significant proportion of patients developmetastatic disease and are initially prescribed androgen deprivation therapy(ADT).However,subsequent sequences of treatments in real-world settings that may improve overall survival remain an area of active *** and methods:Data were collected from 384 patients presenting with de novo metastatic prostate cancer from 2011 to 2015 at a tertiary cancer *** were categorized into surviving(n=232)and deceased(n=152)groups at the end of 3 *** sequence pattern mining techniques(Generalized Sequential Pattern Mining and Sequential Pattern Discovery using Equivalence Classes)were applied to determine the exact order of the most frequent sets of treatments in each ***:Degarelix,as the initial form of ADT,was uniquely in the surviving *** sequence of ADT followed by abiraterone and docetaxel was uniquely associated with a higher 3-year overall *** followed by fosfestrol was found to have a unique niche among surviving patients with a long duration of response to the initial *** who received chemotherapy followed by radiotherapy and those who received radiotherapy followed by chemotherapy were found more frequently in the deceased ***:We identified unique treatment sequences among surviving and deceased patients at the end of 3 *** should be the preferred formof *** who received ADT followed by abiraterone and chemotherapy showed better *** requiring palliative radiation and chemotherapy in any sequence were significantlymore frequent in the deceased group,identifying the need to offer such patients the most efficacious agents and to target them in clinical trial design.

关键词： Hormone therapy Metastatic prostate cancer Sequence mining Survival

Titanasilsesquioxane-Alkylaluminum Catalyst System for Ethylene Polymerization

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Modern Research in Catalysis 2012年第3期1卷 29-42页

作者： Akshay Mehta Gopal Tembe Parimal Parikh girish Mehta Applied chemistry Department S. V. National Institute of Technology Surat India chemical Engineering Department S. V. National Institute of Technology Surat India Reliance Technology Group Reliance Industries Limited Vadodara Manufacturing Division Vadodara India

Homogeneous Ti(IV) complexes covalently anchored to Polyhedral Oligomeric Silsesquioxane (POSS) have been synthesized by the stoichiometric reaction between titanium(IV)alkoxide and (iso-Octyl)7Si7O9(OH)3. These catalyst precursors formulated as [Ti(OR)(iso-Octyl)7Si7O12] were characterized by physicochemical and spectroscopic methods. These supported catalysts are found to be active in polymerization of ethylene at high temperatures in presence of ethylaluminum sesquichloride (Et3Al2Cl3, EASC) as co-catalyst. The polyethylene obtained are generally linear, crystalline and display low molecular weight distribution. The microstructure of the polymer was analyzed by NMR and FT-IR spectroscopic methods which indicated a chain transfer reaction to aluminum. The unique molecular properties of PE formed has been compared with commercial micronized PE wax which find industrial applications in surface coating and ink formulations. The effect of reaction conditions on catalytic behaviour is described.

关键词： POSS Titanasilsesquioxane Polyethylene Ethylaluminum Sesquichloride Polymer Microstructure

Zinc supplementation as an adjunct to standard therapy in childhood nephrotic syndrome-a systematic review

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World Journal of Clinical Pediatrics 2016年第4期5卷 383-390页

作者： girish chandra Bhatt Shikha Jain Rashmi Ranjan Das Department of Pediatrics All India Institute of Medical Sciences Department of Pediatrics All India Institute of Medical Sciences

AIM To evaluate the role of zinc as add on treatment to the "recommended treatment" of nephrotic syndrome(NS)in *** All the published literature through the major databases including IVledline/Pubmed,Embase,and Google Scholar were searched till 31 st December *** lists from the articles were reviewed to identify additional pertinent *** papers concerning the role of zinc in childhood NS were reviewed by the authors,and the data were extracted using a standardized data collection *** trials(RCTs) comparing zinc vs placebo was *** of zinc was studied in both steroid sensitive and steroid dependent/frequent relapsing *** primary outcome measure was the risk of relapse in 12 *** secondary outcome measures were mean relapse rate per patient in 12 mo,mean relapse rate per patient in 6 mo,risk of infection associated relapse in 12 mo,cumulative dose of steroids in two groups,mean length of time to next relapse,adverse effects of therapy,and change in serum zinc *** Of 54 citations retrieved,a total of 6 RCTs were *** was used at a dose of 10-20 mg/d,for the duration that varied from 6-12 *** to placebo,zinc reduced the frequency of relapses,induced sustained remission/no relapse,reduced the proportion of infection episodes associated with relapse with a mild adverse event in the form of metallic *** GRADE evidence generated was of "very low-quality".CONCLUSION Zinc may be a useful additive in the treatment of childhood *** evidence generated mostly was of "very low-quality".We need more good quality RCTs in different country setting as well different subgroups of children before any firm recommendation can be made.

关键词： Nephrotic syndrome Pediatric Relapse Zinc Micronutrient