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Petrology of Spinel-Lherzolite Xenoliths from Mazéléand Others Northen Xenoliths Localities of Cameroon Volcanic Line: Exchange Reactions and Equilibrium State

作者： gilles ne?ret. [translation Chris Miller].

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Open Journal of Geology 2024年第5期14卷 629-653页

作者： Nguihdama Dagwai Kamgang Pierre Mbowou Gbambié Isaac Bertrand Chazot gilles Ngounouno Ismaïla Department of Life and Earth Sciences Higher Teachers&#8217 Training College University of Maroua Maroua Cameroon Department of Earth Sciences Faculty of Science University of Yaound&#233 1 Yaound&#233 Cameroon Department of Mineral Prospecting and Exploration Technologies School of Geology and Mining Engineering University of Ngaoundere Meiganga Cameroon Ocean Geosciences Laboratory European University Institute of the Sea (IUEM) Brest France

The alkaline volcanism of the Cameroon Volcanic Line in its northern domain has raised many fresh enclaves of peridotites. The samples selected come from five (05) different localities (Liri, in the plateau of Kapsiki, Mazélé in the ne of Ngaoundéré, Tello and Ganguiré in the SE of Ngaoundéré and Likok, locality located in the west of Ngaoundé). The peridotite enclaves of the above localities show restricted mineralogical variation. Most are four-phase spinel-lherzolites, indicating that this is the main lithology that forms the lithospheric mantle below the shallow zone. No traces of garnet or primary plagioclase were detected, which strongly limits the depth range from which the rock fragments were sampled. The textures and the wide equilibrium temperatures (884˚C - 1115˚C) indicate also entrainment of lherzolite xenoliths from shallow depths within the lithosphere and the presence of mantle diapirism. The exchange reactions and equilibrium state established in this work make it possible to characterize the chemical composition of the upper mantle of each region and test the equilibrium state of the phases between them. Variations of major oxides and incompatible elemental concentrations in clinopyroxene indicate a primary control by partial melting. The absence of typical “metasomatic” minerals, low equilibration temperatures and enriched LREE patterns indicate that the upper mantle below septentrional crust of Cameroun underwent an event of cryptic metasomatic enrichment prior to partial melting. The distinctive chemical features, LREE enrichment, strong U, Ce and Pr, depletion relative to Ba, Nb, La, Pb, and T, fractionation of Zr and Hf and therefore ligh high Zr/Hf ratio, low La/Yb, Nb/La and Ti/Eu are all results of interaction of refractory peridotite residues with carbonatite melts.

关键词： Xenoliths Upper Mantle Northern Region Adamawa Cameroon Volcanic Line Exchange Reaction

Faecal calprotectin and magnetic resonance imaging in detecting Crohn's disease endoscopic postoperative recurrence

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World Journal of Gastroenterology 2018年第5期24卷 641-650页

作者： Pierre Baillet Guillaume Cadiot Marion Goutte Felix Goutorbe Hedia Brixi Christine Hoeffel Christophe Allimant Maud Reymond Hélène Obritin-Guilhen Benoit Magnin gilles Bommelaer Bruno Pereira Constance Hordonneau Anthony Buisson Université Clermont Auvergne CHU Clermont-Ferrand Service de radiologie CHU de Reims Service d’Hépato-Gastro Entérologie Université Clermont Auvergne Inserm 3iHP CHU Clermont-Ferrand Service d’Hépato-Gastro Entérologie Université Clermont Auvergne Inserm U1071 CH de Bayonne Service d’Hépato-Gastro Entérologie CHU de Reims Service de radiologie CHU Clermont-Ferrand DRCI Unité de Biostatistiques

AIM To assess magnetic resonance imaging(MRI) and faecal calprotectin to detect endoscopic postoperative recurrence in patients with Crohn's disease(CD).METHODS From two tertiary centers, all patients with CD who underwent ileocolonic resection were consecutively and prospectively included. All the patients underwent MRI and endoscopy within the first year after surgery or after the restoration of intestinal continuity [median = 6 mo(5.0-9.3)]. The stools were collected the day before the colonoscopy to evaluate faecal calprotectin level. Endoscopic postoperative recurrence(POR) was defined as Rutgeerts' index ≥ i2b. The MRI was analyzed independently by two radiologists blinded from clinical *** Apparent diffusion coefficient(ADC) was lower in patients with endoscopic POR compared to those with no recurrence(2.03 ± 0.32 vs 2.27 ± 0.38 × 10^(-3) mm^2/s, P = 0.032). Clermont score(10.4 ± 5.8 vs 7.4 ± 4.5, P = 0.038) and relative contrast enhancement(RCE)(129.4% ± 62.8% vs 76.4% ± 32.6%, P = 0.007) were significantly associated with endoscopic POR contrary to the magnetic resonance index of activity(Ma RIA)(7.3 ± 4.5 vs 4.8 ± 3.7; P = 0.15) and MR scoring system(P = 0.056). ADC negative predictive value(NPV) = 0.65] and RCE > 100%(sensitivity = 0.75, specificity = 0.81, PPV = 0.75, NPV = 0.81) were the best cutoff values to identify endoscopic POR. Clermont score > 6.4(sensitivity = 0.61, specificity = 0.82, PPV = 0.73, NPV = 0.74), Ma RIA > 3.76(sensitivity = 0.61, specificity = 0.82, PPV = 0.73, NPV = 0.74) and a MR scoring system ≥ MR1(sensitivity = 0.54, specificity = 0.82, PPV = 0.70, and NPV = 0.70) demonstrated interesting performances to detect endoscopic POR. Faecal calprotectin values were significantly higher in patients with endoscopic POR(114 ± 54.5 μg/g vs 354.8 ± 432.5 μg/g; P = 0.0075). Faecal calprotectin > 100 μg/g demonstrated high perfor

关键词： Faecal calprotectin Magnetic resonance imaging Postoperative recurrence Crohn’s disease Clermont score Magnetic resonance index of activity

Efficacy of 2LPAPI^®, a Micro-Immunotherapy Drug, in Patients with High-Risk Papillomavirus Genital Infection

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Advances in Infectious Diseases 2016年第1期6卷 7-14页

作者： gilles Thomas Hélène Cluzel Jacqueline Lafon Jacques Bruhwyler Béatrice Lejeune Private Gynecology Practice Perpignan France Labo’Life France sarl Pescalis Les Magny France ECSOR sa/nv Blanmont Belgium Labo’Life Belgium sprl Les Isnes Belgium

Human papillomaviruses (HPVs) are well known for being linked to the development of cervical cancers, most of them being caused by the high-risk (HR) oncogenic genotypes, mainly 16 and 18. The efficacy of 2LPAPI® (Labo’Life), a micro-immunotherapy homeopathic drug, has been evaluated in HR-HPV infected women (n = 18), in a private gynecology practice, by comparing them to an untreated control group (n = 18). Patients were 20 to 45 years old and had cytology with Atypical Squamous Cells of Undetermined Significance (ASCUS) or Low grade Superficial Intra Lesions/ Cervical Intraepithelial neoplasia Grade I (LSIL/CINI). Patients freely chose to be treated with the drug or not. Those deciding not to take the drug remained untreated and were followed as a control group. The drug was taken at the regimen of one capsule per day during 6 months. HR-HPV and cytology were evaluated at 6 and 12 months. After 12 months, HR-HPV was cleared in 78% of the patients taking the drug versus 44% in those not taking it (p = 0.086). In patients over 25 years, HR-HPV clearance in the treated group was significantly higher (81.3%) than in the control group (20%) (p = 0.004). The difference in the regression of the lesion grades almost reached statistical significance (p = 0.053). This follow-up confirms that the micro-immunotherapy drug 2LPAPI® is a safe and effective therapeutic approach to treat HR-HPV cervical lesions in women over 25 years.

关键词： High-Risk Human Papillomavirus Micro-Immunotherapy Genital Infection Homeopathy 2LPAPI®

Anorectal Malformations Operated at University Hospital Brazzaville

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Open Journal of Pediatrics 2020年第2期10卷 263-273页

作者： Caryne Mboutol-Mandavo Eustache Brani Dzipara Jean-Claude Miéret.Irène Patricia Lucienne Ondima Isnack Ngakosso-Ngalouo Jean-Robert Mabiala-Babéla Faculty of Health Sciences Marien Ngouabi University Brazzaville Congo Department of Pediatric Surgery University Hospital of Brazzaville Brazzaville Congo Department of Pediatric Infants University Hospital of Brazzaville Brazzaville Congo

Aim: To appreciate the care of children operated for an anorectal malformation. Materials and methods: It was a ret.ospective study carried out from January 2014 to December 2018 (5 years) in the department of pediatr... 详细信息

Aim: To appreciate the care of children operated for an anorectal malformation. Materials and methods: It was a retrospective study carried out from January 2014 to December 2018 (5 years) in the department of pediatric surgery of university hospital of Brazzaville. Results: We retained 35 files including 20 boys and 15 girls. The mean age of discovery of the malformation was 1.7 days (range 0 and 4 days). On physical examination, we found intestinal occlusion in 22 patients (62.9%): the absence of an anal opening (62.9%), abdominal bloating with tympanism were the most represented signs. (57.1%). There were 13 cases (37.1%) of anorectal malformations high, 12 cases (34.3%) of low and 10 cases (28.6%) of intermediate. There were 20 cases (57.1%) of anorectal malformations without fistula and 15 cases (42.9%) with fistula. The mean age at the time of the anal plasty was 12.7 months (range 2 days and 14 years). We performed the anorectoplasty according to the Peňa and De Vries technique in 26 cases (74.3%), perineal anoplasty in 5 cases (14.3%) and a transposition of the fistula in 4 cases (11.4%). Twenty-seven patients (77.1%) were reviewed with an average follow-up of 2.7 years (1 year and 5 years extremes). The anus had a normal aspect in 20 cases (74.1%). We evaluated anal continence according to the Krickenbeck criteria in 10 patients aged over 3 years, and six had good results.

关键词： Anorectal Malformations Anorectoperineoplasty Child

De l'unité de l'Europe à l'Union européenne

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De l'unité de l'Europe à l'Union européenne

Management of Immediate Postpartum Hemorrhage at the University Hospital Center of the Sino-Central African Friendship

北京论坛（2006）文明的和谐与共同繁荣—对人类文明方式的思考

作者： gilles PECOUT Ecole Normale Supérieure de Paris

Is it possible to conceptualize a continent ? La question se pose-t-elle seulement pour l’Europe ? Le discours public comme l’historographie nous montrent combien en Asie et en Afrique-pour ne pas parler de l’Amerique ou le paradigme d’exclusivite continentale est officiellement utilise au profit d’un seul Etat par la

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Open Journal of Obstetrics and Gynecology 2023年第11期13卷 1783-1790页

作者： Roch M’betid-Degana gilles-Davy Kossa-Ko-Ouakoua Geniva Gracelia Vanciane M’betid-Degana Gamaliel Kerebi Sandrine Sana-Ozako Durant Poutou-Piri Samuel Gondje Appolinaire Hepatraud Eugène Serdouma Antoine Doui-Doumgba Department of Gynecology and Obstetrics University Hospital Center of the Sino-Central African Friendship Bangui Central African Republic Department of Gynecology and Obstetrics Camp Henri IZAMO Hospital (National Gendarmerie) Bangui Central African Republic General Surgery Department University Hospital Center of the Sino-Central African Friendship Bangui Central African Republic

Introduction: Immediate postpartum hemorrhages constitute a frequent maternal complication and remain at the forefront of maternal death in our countries. Objective: Contribute to improving the management of immediate postpartum hemorrhage in our context with a view to reducing maternal mortality. Patients and Methods: We conducted a ret.ospective descriptive and analytical study over a period of 12 months from January 1st to December 31st 2020. Results: We collected a total of 109 files on a total of 4360 deliveries. The frequency of postpartum haemorrhages was of the order of 2.5%. The most represented age group was between 20 and 24 years old. Pauciparas represented the majority of our study population. 64.5% of patients were uneducated. These hemorrhages occurred in patients who often gave birth outside the department with 63.8%. The main causes of postpartum hemorrhage were cervical tears (51.2%) and partial placental ret.ntion (30.7%). The majority of these deliveries (48.8%) were carried out by midwives followed by assistant midwives (33.2%). Active management of the third period of delivery was systematic and immediate followed by the valve examination completed by the infusion of oxytocin in case of uterine atony, tranexamic acid ans misoprostol intrarectally. In the event of persistent hemorrhage, suture of the cervical lesions, ligation of the cervical vessels or even laparotomy either for the selective ligation of the blood vessels or for the hysterectomy for hemostasis were practiced. We do not have a Nalador, nor a Bakry balloon, nor an Interventional Radiology service for embolization of the uterine arteries. We deplore 1.3% of deaths from afibrinogenemia. Conclusion: The frequency of immediate postpartum hemorrhages is lower in our health facility. This is due to the rapid handling of cases. Improving the quality of services offered to women during childbirth can further help reduce the frequency of these hemorrhages.

关键词： Haemorrhage Postpartum Immediate University Hospital Center of the Sino-Central African Friendship

Petrogenetic characterization of the host rocks of the Sanaga iron ore prospect,southern Cameroon

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Acta Geochimica 2023年第2期42卷 195-220页

作者： Tasin Godlove Bafon Anthony Temidayo Bolarinwa Cheo Emmanuel Suh Temesgen Oljira Bekele Ayele Bedada gilles Nyuyki Ngoran Kevin Ijunghi Ateh Boris Martial Keuko Djoumbissie Cho Terence Ngang Department of Geology Pan African University Life and Earth Science InstituteUniversity of IbadanIbadanNigeria Department of Geology Mining and Environmental ScienceUniversity of BamendaP.O.Box 39BambiliCameroon Explorers 33 Consulting Group Sarl P.O.Box 6666YaoundeCameroon Department of Earth Sciences Faculty of ScienceUniversity of Yaounde IP.O.Box 812YaoundeCameroon

The Sanaga iron ore prospect is a recent discovery in the Nyong Series with a resource estimated at 82.9 Mt at 32.1%Fe and whose origin remains *** mineralization occurs as ne-SW oriented discontinuous lenticular bodies of magnetite-bearing pyroxenegneisses(MPG)hosted by ortho-derived *** amphibolites are *** MPG mineral assemblage consists of quartz-magnetite-orthopyroxene-garnet-tremolite/actinolite exhibiting a granoblastic texture,which is characteristic of granulite facies *** granodioritic gneisses show compositional features of the tonalite-trondhjemite-granodiorite *** trace and REE element geochemistry indicate their protolith melt resulted from the partial melting of a subducted oceanic slab,with interaction with the overlying mantle wedge during *** amphibolites show enrichment in LILE with negative Ta–Nb and Zr–Hf indicating arc-related magmas generated by partial melting of a sub-continental lithospheric mantle source with metasomatism by subduction-related *** MPG exhibits oxidation-exsolution features characterized by ilmenite lamellae,with hematite fracture-fillinginmagnetite,andlacksfeatures characteristic of typical BIF such as LREE depletion relative to HREE,positive Eu,La,and Y *** on the results of this study,we interpret.the Sanaga MPG as a possible skarn-type mineralization formed by the metamorphism/metasomatism of a possible BIF *** results of this study compare with similar magnetite-rich mineralization in the Sa o Francisco craton in northeastern Brazil and enhance the correlation of pre-drift reconstructions of the Sa o Francisco–Congo Cratons.

关键词： Magnetite-pyroxene-gneiss Metasomatism Ilmenite exsolution Hematite fracture-filling Skarn type mineralization Nyong Series

Isolation and Identification of Two Antibacterial Agents from <i>Chromolaena odorata</i>L. Active against Four Diarrheal Strains

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Advances in Microbiology 2013年第1期3卷 115-121页

作者： Ménonvè Atindehou Latifou Lagnika Bernard Guérold Jean Marc Strub Minjie Zhao Alain Van Dorsselaer Eric Marchioni gilles Prévost Youssef Haikel Corinne Taddéi Ambaliou Sanni Marie-Hélène Metz-Boutigue CNRS UMR7178 University of Strasbourg Strasbourg France EA 7290 University of Strasbourg Strasbourg France Faculté de Chirurgie Dentaire Université de Strasbourg Strasbourg France Inserm UMR 1121 University of Strasbourg Strasbourg France IPHC-DSA CNRS University of Strasbourg Strasbourg France Université d’Abomey-Calavi Laboratoire de Biochimie et Biologie Moléculaire (LBBM) Cotonou Bénin

Chromolaena odorata L (Asteraceae) is a bad invasive plant, found in the humid tropics and sub-tropics worldwide. It is used against dysentery, diarrhea, malaria, wound healing, headache and toothache in traditional medicine. In the present study, we investigated the antibacterial activities of different leaves extracts of Chromolaena odorata L. (cyclohexane, dichloromethane, ethyl acetate and butanol) against four clinical diarrheal strains (Klebsiella oxytoca, Salmonella enterica, Shigella sonnei and Vibrio cholera). We demonstrated that C. odorata leaves extracts show an antibacterial activity between 0.156 and 1.25 mg/mL. Bioassay-guided chromatography by bioautography with iodonitrotetrazolium-based colorimetric assay allowed the isolation and identification of two active compounds. After the combination of RP-HPLC, mass spectrometry analysis, 1D and 2D-NMR spectroscopy, we isolated and characterized two active molecules corresponding to 3’,4’,5,6,7-Pentamethoxyflavone (Sinensetin) and4’,5,6,7-Tetramethoxyflavone (Scutellareintetramethyl ether).

关键词： Chromolaena odorata 3’ 4’ 5 6 7-Pentamethoxyflavone (Sinensetin) 7-Tetramethoxyflavone (Scutellareintetramethyl ether) Antibacterial Activity Diarrheal Strains