检索结果-南通市图书馆

Association between Plasma Myeloperoxidase and Free 3-Nitrotyrosine Levels in Patients with Coronary Artery Disease

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Clinical Medicine 2013年第3期4卷 158-164页

作者： Morteza Pourfarzam Ahmad Movahedian Nizal Sarrafzadegan gholam Basati Saed Ziaaldin Samsamshariat Cardiovascular Research Center Isfahan Cardiovascular Research Institute Isfahan University of Medical Sciences Isfahan Iran Department of Clinical Biochemistry Faculty of Medicine Ilam University of Medical Sciences Ilam Iran Pharmaceutical Sciences Research Centre Department of Clinical Biochemistry School of Pharmacy and Pharmaceutical Sciences Isfahan University of Medical Sciences Isfahan Iran Pharmaceutical Sciences Research Centre Department of Clinical Biochemistry School of Pharmacy and Pharmaceutical Sciences Isfahan University of Medical Sciences Isfahan Iran.

Objective: Myeloperoxidase (MPO) is an inflammatory enzyme that is mainly released by activated neutrophils and monocytes. 3-nitrotyrosine (NT) is a stable inflammatory end product of MPO that is produced through nitrosylation of free and protein-bound tyrosines. Determination of the exact levels of free NT is technically a challenging matter. Also, there is limited information about the relationship between MPO and free NT levels and elevation of them in the plasma of patients with coronary artery disease (CAD). Therefore, we sought to determine the exact level of plasma free NT with a simple and exquisite technique in CAD patients. Methods: This study included 50 stable angina, 50 unstable angina patients, and 50 control subjects. Plasma MPO concentration was measured with an immunoassay method. Plasma free NT level was determined by a modified HPLC-fluorescence method. Lipid profile, high sensitivity C-reactive protein (hsCRP) and other clinical risk factors of patients were also assigned. Results: Plasma level of free NT was efficiently measured by the HPLC-fluorescence method. Plasma levels of MPO and NT were significantly higher in patients with stable and unstable CAD than in control subjects (P < 0.001). There was a significant correlation between the two substances in CAD patients (P < 0.001). Conclusions: We determined plasma free NT levels with a sensitive HPLC-fluorescence method with some modifications in a clinical scale. Plasma levels of MPO and NT were profoundly elevated in CAD patients. The significant relationships of the two substances and elevation of them may have useful clinical implication in patients with stable and unstable CAD.

关键词： Myeloperoxidase 3-Nitrotyrosine Stable Unstable CAD

Evaluation on Water Resources and Determining the Values of Exported and Imported Virtual Water in Hashtgerd Region

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Ecology 2016年第6期6卷 367-376页

作者： Seyed Jalal Yadollahi Nooshabadi Mohammad Reza Jahansuz Nasser Majnoun Hosseini gholam Reza Peykani College Agriculture & Natural Resources University of Tehran Karaj Iran

The concept of virtual water in recent years has been proposed with the world’s water resource consumption management approach. Hashtgerd study area is one of 609 study areas of the country that is located entirely in Alborz Province. Average annual rainfall in this region was about 200 to 340 mm and the average agricultural production per year was more than one million tons and had more than 16 million cubic meters surplus recovery from underground water resources. The aim of this study is to evaluate resources and amounts of virtual water in the agricultural sector of the study area and its impact on the area water resources balance and ultimately provide solutions to reduce water consumption by the agricultural sector. The most important exported water products in Hashtgerd area in order of importance are peaches and nectarines (33% of water exports), plums (15% of water exports), vegetables (5.14 percent of water exports), cherry (4.7% of water exports) and wheat (6.5 percent of water exports). Virtual water trade balance of agricultural and horticultural products in the digital range is equal to 260+ million cubic meters. Density of agricultural lands can be mentioned as the main reasons for positive balance of virtual water trade in this area.

关键词： Virtual Water Agriculture Consumption Hashtgerd

Spatial Variability of Shear Wave Velocity Using Geostatistical Analysis in Mashhad City, NE Iran

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Geology 2014年第8期4卷 354-363页

作者： Azam Ghazi Naser Hafezi Moghadas Hossein Sadeghi Mohammad Ghafoori gholam Reza Lashkaripour Department of Geology Faculty of Sciences Ferdowsi University of Mashhad Mashhad Iran

Shear wave velocity (Vs) is one of the most important parameters of a geological model to assess the site effect and the ground response. In this paper the spatial variability of shear wave velocity in Mashhad capital city are investigated. For this purpose, 243 Vs profiles of different projects throughout the city were used. Based on the Vs profiles the iso-level maps of the Vs interfaces 300, 500, 750, 950 and 1200 m/s were obtained by kriging interpolation method. The best semivariogram models were obtained with changing the effective parameters and assessing the components of the models and spatial dependence. The best models for the entire interfaces were exponential. Based on these models, the spatial dependence of depth data was moderate to strong. The performance of interpolations was checked by cross-validation and its indices?i.e. mean standardized prediction errors (MSPR), root mean square prediction errors (RMSPE), average kriging standard error (AKSE), and root mean square standardized prediction errors (RMSSPE) were assessed. A trend of depth increasing towards the northeast was observed at all of the interfaces.

关键词： Kriging Interpolation Accuracy Vs Interface Mashhad City

Comparing Ecological Functions of Eastern and Southern Slopes of a Rangeland Ecosystem in Chaharbagh Region, Golestan Province, Iran

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Science and Engineering(B) 2012年第3期1卷 403-409页

作者： Reza Dehghani Bidgoli Mohammad Pessarakli gholam. Ali Heshmati Marzieh Yousefi Najafabadi Department of Rangeland Management Gorgan University of Agricultural Sciences and Natural Resources Gorgan *** Ir an School of Plant Sciences The University of Arizona Tucson Arizona 85721 USA Abouriham Campus The University ofTehran Pakdasht *** Iran

Getting aware of one kind of soil surface attributs is very important. Assessment of important attributes of soil and vegetation can help us to be aware of rangeland potential and help us to determine its situation. The goal of this research is to determine some plant and soil indicators of hilly winter rangelands of Eastern and Southern slopes of Chaharbagh region in Golestan province. By considering plant cover and soil surface attributes, it used the SSCC （soil surface classification） method to assess soil surface attributes. The length and width of ecological patches were measured in the forms of lichen, lichen-Grass, forbs, shrub and bare soil inter patches with litter. Also in this research, it measured the 11 soil surface parameters. These parameters are belonging to three main soil attributes stability, infiltration and nutrient cycles. These three indicators were measured in east and west of Eastern and Southern slopes of this ecosystem and showed significance differences （p 〈 0.05） in shrub, forbs and lichen-grass. In southern and especially in west aspect, these indicators in shrub were more than Eastern. But, in lossy hill of Eastern, lichen-grass patch is more significant. The most important ecological indicators of east landscapes of this region are forbs and lichen-grass.

关键词： Ecological function soil attributes soil stability infiltration nutrient cycles.

Correlation of Breast Cancer with the Epstein Bar Virus and Human Cytomegalovirus Frequency and the Expression of Estrogen Receptor-Beta and IL-6 Receptor in Iraqi Women

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural Science 2018年第5期10卷 182-192页

作者： Hayder Kadhim A. L. Shadood Saad Abdul-Aziz Atiya gholam Ali Kardar Department of Medical Biotechnology School of Advanced Technologies in Medicine Tehran University of Medical Sciences-International Campus Tehran Iran Department of Microbiology College of Medicine DHI-QAR University DHI-QAR Iraq

Background and Purpose: In Iraq, breast cancer is the common type of female malignancy. Increasing indication in the past 10 years proposes that Epstein-Barr virus (EBV) and cytomegalovirus (HCMV) are related with some human malignancies including breast cancer. The part of EBV and HCMV in breast cancer is still debatable. Unraveling this relationship is potentially?essential for better understanding of breast cancer etiology, early recognition and possibly inhibition of breast cancer The purpose of the current study is to detect the correlation between EBV,?HCMV and breast cancer in Iraqi women and expression of ERB and IL-6R in breast tissues. Patients and Methods: The study was done on paraffin-embedded?tissues of eighty Iraqi patients with breast cancer in addition to twenty normal breast tissues as controls. Both controls and breast cancer mass?are?divided into two sections, one for DNA extraction and amplification by real time PCR for detect EBV and HCMV occurrence while the other section processed for protein expression (IL-6R, ERB) by immunohistochemistry technique (IHC). Results: The result showed that 18/80 (22.5%) and 5/80 (6.25%) sample from breast cancer were positive for EBV and HCMV respectively, with the?p-value?= 0.062 and 0.597 and the results of IHC for IL-6R and ERB expression in patients with breast cancer were 37/80 (46.25%) and 30/80 (37.5%)?p-value?=?(0.274 and 0.381) respectively. Conclusions: Our findings suggest that EBV might have a role in the pathogenesis of breast cancer and absence this role between HCMV with breast cancer. These findings were based mainly on EBV, HCMV detection by PCR technique. So,?the rolesof these viruses in the development of breast cancer remain unclear.

关键词： Cytomegalovirus Epstein-Barr Virus Breast Cancer Protein Expression

Epidemiology of livestock-related injuries in a major trauma center in Kashan, Iran

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Traumatology 2013年第1期16卷 36-39页

作者： Mahdi Mohammadzadeh Mehrdad Hosseinpour gholam Reza Khosravi Azadeh Sadat Mirzadeh Hoda Jazayeri Trauma Research Center Kashan University of Medical Sciences Kashan IR Iran

Objective： Livestock-related injuries are one of the important factors causing morbidity and mortality in patients admitted to hospital. Treatment of these patients is still a major problem in health care system. The aim of current study was to assess the epidemiology of livestock-related injuries in a major trauma center in Iran from 2006 to 2011. Methods： In a prospective study, patients with live- stock-related injuries who were consecutively admitted to the trauma center in Kashan, Iran between 2006 and 2011 were evaluated. The data collected included patient＇s demographics, place and nature of accident, damaged organ, educational level, transport and outcome. Data were expressed as mean±standard deviation. Results： A total of 129 patients were included in this study, accounting for 0.3% of all trauma admission （40 273 cases）. The mean age was （55.27±14.45） years. Men were affected four times more than women. Falling down from livestock is the main mechanism of trauma in all groups. Upper and lower extremities were most frequently injured （n=72）, followed by the head, neck and spine （n=33 for each）. There was one death resulting from livestock-related injury in this study. Conclusion： Despite the low incidence, livestock-related injuries can damage major organs of human body and therefore appropriate training program to increase the safety awareness in home and outdoor is very important.

关键词： Epidemiology Livestock Iron: Wounds and injuries

Detection of leptospiral antibodies by microscopic agglutination test in north-east of Iran

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2011年第3期1卷 227-229页

作者： Ehsanollah Sakhaee gholam Reza Abdollah pour Department of Clinical Sciences Faculty of Veterinary MedicineShahid Bahonar University of Kerman Department of Clinical Sciences Faculty of Veterinary MedicineUniversity of Tehran

Objective:To detect leptospiral antibodies by microscopic agglutination test(MAT) in northeast of ***:This study was conducted to evaluate prevalence of human leptospiral infections by *** six current reference strains of Leptospira interrogans in north-east of Iran.A total of 285 serum samples were collected from three north-east provinces of Iran,from December,2009 to June,***:Antibodies were detected at least against one serovar of Leptospira interrogans in 45 sera(15.79%) among 283 samples at a dilution 1:100 or *** titers against more than one serovar were detected in 24 sera of the positive ***, there were 75 positive reactions against different serovar of Leptospira *** titers were recorded against serovar icterohaemorrhagiae(31 samples),hardjo(26 samples), grippotyphosa(7 samples),pomona(5 samples),canicola(4 samples) and ballum(***). Conclusions:In present study the most prevalent(Leptospira icterohaemorrhagiae) and the least prevalent(Leptospira ballum) serovar are different from previous ***,species and prevalence of serovars change during the lime in one area and between regions.

关键词： Leptospirosis Microscopic agglutination test Human Iran Prevalence Leptospiral infection Serovar

Stabilizing Effects of Ethanolic Extract of Mastic Gum on Microtubule Polymers:an In Vitro Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Human Physiology 2019年第2期1卷 18-25页

作者： Ali Dadras Fatemeh Shahrokhi Asl gholam Hossein Riazi Shahin Ahmadian Tahereh Javdani Khalife Neuro-organic Lab Institute of Biochemistry and Biophysics(IBB)University of TehranTehranIran

Terpenoids are novel natural products isolated from mastic *** gum was obtained from the Pistacia Lentiscus *** investigations have documented medical and pharmacological properties of mastic gum such as memory enhancement,antifungal,and antibacterial *** was astonishing to study the possible interaction of mastic gum extract with microtubule proteins which are involved in memory and consciousness since the administration of mastic gum is evidenced in the improvement of brain *** a number of studies have demonstrated the effect of microtubule dynamics on mammals'memory,in this study,we investigated the effect of Oxygenated Sesquiterpenes(OST)on microtubule polymerization in *** was purified from the ethanolic extract of mastic *** results revealed that OST induces microtubule polymerization;however,microtubule depolymerization was not affected and fluorometric assays showed conformational changes of tubulin in the presence of *** interestingly found that colchicine was unable to inhibit MT assembly in the presence of OST and OST was solely more efficient than the combination of OST with paclitaxel for elevating microtubule polymerization *** hope that OST could be a promising agent for memory enhancement and the treatment of neurodegenerative diseases as a novel tubulin-binding compound.

关键词： Pistacia lentiscus Mastic gum Oxygenated Sesquitrepene(OST) Tubulin Microtubule

Geodynamics of Dikes in North of Saveh

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Ecology 2015年第9期5卷 452-459页

作者： Mohammad-Hasan Bazoobandi Mohammad-Ali Arian Mohammad-Hashem Emami gholam-Reza Tajbakhsh Abdollah Yazdi Department of Geology Faculty of Science North Tehran Branch Islamic Azad University Tehran Iran Department of Geology Faculty of Science Islamshahr Branch Islamic Azad University Tehran Iran Department of Geology Faculty of Science Yazd University Yazd Iran Department of Geology Faculty of Science Kahnooj Branch Islamic Azad University Kerman Iran

Dikes can be divided into sheeted, feeder, cone and swarm types based on the origin and the formation. A group of dikes that are formed in dense in a relatively broad zone influenced by a particular tectonic regime are referred to as swarm dikes. Swarm dikes have numerous applications such as locating mantle plume centers, determining areas of longstanding tensions and detection of deformation networks. The purpose of this article is classified swarm dikes of “North of Saveh” based on previous studies. In one study, swarm dikes are classified based on their initial geometry into five types of I, II, III, IV and V. According to this classification, our study has been shown that the dikes in north of Saveh are of type IV. In another study, the swarm dikes are classified into three types: parallel, large radial and small radial. According to the classification, our study has been shown that the dikes of North Saveh are parallel that have arisen by tensions caused by the collision of the Arabian plate and the Central Iran plate. In addition to original tensions in the region, local faults have been effective on the arrangement and the establishment of dikes.

关键词： Swarm Dikes Locating Mantle Plume Dikes in North of Saveh Dikes Classification