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Antimalarial activity of the aqueous extract of Euphorbia cordifolia Elliot in Plasmodium berghei-infected mice

Asian Pacific Journal of Tropical Medicine 2020年第4期13卷 176-184页

作者： Raceline Gounoue Kamkumo Jaures Marius Tsakem Nangap Lauve Rachel Tchokouaha Yamthe FlorenceNgueguim Tsofack Patrick Valère Tsouh Fokou mariscal Brice Tchatat Tali Théophile Dimo Fabrice FekamBoyom Department of Animal Biology and Physiology University of Yaounde 1Cameroon Institute of Medical Research and Medicinal Plant Studies YaoundeCameroon Department of Biochemistry University of Yaounde 1Cameroon

Objective:To evaluate the antimalarial activity of the aqueous extract of Euphorbia(E.)cordifolia Elliot against Plasmodium(P.)berghei-infected ***:Thirty healthy Swiss mice were intraperitoneally inoculated with 200μL of *** parasitized-erythrocytes and divided into five groups,and then daily treated for 5 d with single dose of 10 mL/kg of distilled water for malaria control,10 mg/kg of chloroquine for the chloroquine control and 100,200 and 400 mg/kg of the aqueous extract of *** for the three test *** was monitored by *** the end of the treatment,animals were sacrificed,and blood was collected for haematological and biochemical *** were collected for biochemical and histopathological *** significance(P<0.05)was evaluated by analysis of variance followed by the Tukey post-test using Graphpad prism ***:*** extract decreased the parasite load to 2.46%,with an effective dose(ED50)of 113.07 mg/kg compared to the malaria group where the parasite load increased to(46.46±10.28)%.*** extract prevented hypoglycaemia,anaemia,leucocytosis and thrombocytopenia,attenuated the increase of transaminases activities,bilirubin and creatinine rate,and improved catalase and superoxide dismutase activities,while reducing malondialdehyde contents in the liver and *** extract significantly prevented histological damages observed in the malaria control *** acute toxicity sign was observed in mice with plant extract at the dose up to 5000 mg/***:*** extract at 200 and 400 mg/kg showed significant antimalarial *** results support its traditional use in the treatment of malaria.

关键词： Antimalarial activity Curative effects Euphorbia cordifolia Plasmodium berghei

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Host-parasite interactions in perpetual darkness:Macroparasite diversity in the cavefish Astyanax mexicanus

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Zoological Research 2023年第4期44卷 782-792页

作者： Ana Santacruz David Hernández-Mena Ramses Miranda-Gamboa gerardo Pérez-Ponce De León Claudia Patricia Ornelas-García Departamento de Zoología Instituto de BiologíaUniversidad Nacional Autónoma de MéxicoMéxico City CP 04510México Departamento de Sistemas y Procesos Naturales Escuela Nacional de Estudios Superiores Unidad MéridaUcúYucatán CP 97357México Instituto de Energías Renovables Universidad Nacional Autónoma de MéxicoTemixcoMorelos CP 62580México Colección Nacional de Peces Departamento de ZoologíaInstituto de BiologíaUniversidad Nacional Autónoma de MéxicoMéxico City CP 04510México Stowers Institute for Medical Research Kansas CityMO 64110USA

Astyanax mexicanus has repeatedly colonized cave environments,displaying evolutionary parallelisms in many troglobitic *** being a model system for the study of adaptation to life in perpetual darkness,the parasites that infect cavefish are practically *** this study,we investigated the macroparasite communities in 18 cavefish populations from independent lineages and compared them with the parasite diversity found in their sister surface fish populations,with the aim of better understanding the role that parasites play in the colonization of new *** the cavefish populations,we identified 13 parasite taxa,including a subset of 10 of the 27 parasite taxa known for the surface *** infecting the cavefish belong to five taxonomic groups,including trematodes,monogeneans,nematodes,copepods,and *** are the most dominant group,found in 14 *** macroparasites include species with direct life cycles and trophic transmission,including invasive ***,paired comparisons indicate higher parasite richness in the cavefish than in the surface *** variation in parasite composition across the caves suggests historical and geographical contingencies in the host-parasite colonization process and potential evolution of local *** base-line data on parasite diversity in cavefish populations of *** provides a foundation to explore the role of divergent parasite infections under contrasting ecological pressures(cave *** environments)in the evolution of cave adaptive traits.

关键词： Adaptation Metazoan parasites Niche change Parasite assemblage Prevalence

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Rayleigh waves from correlation of seismic noise in Great Island of Tierra del Fuego,Argentina:Constraints on upper crustal structure

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Geodesy and Geodynamics 2018年第1期9卷 2-12页

作者： Carolina Buffoni Martin Schimmel Nora Cristina Sabbione María Laura Rosa gerardo Connon Faculty of Astronomical and Geophysical Sciences National University of La PlataPaseo Del Bosque Sin B1900F WAArgentina Institute of Earth SciencesJaume Almera-CSIC Lluis SoléSabarfs S/n Barcelona E-08028Spain Astronomical Station of Rio Grande(EARG) Ruta C y Acceso Aeropuerto9420EARRfo GrandeArgentina National Scientific and Technical Research Council(CONICET) Av.Rivadavia 1917 C1033AAJAutonomous City of Buenos AiresArgentina

In this study, the ambient seismic noise cross-correlation technique is applied to estimate the upper structure of the crust beneath Great Island of Tierra del Fuego（TdF）, Argentina, by the analysis of shortperiod Rayleigh wave group velocities. The island, situated in the southernmost South America, is a key area of investigation among the interaction between the South American and Scotia plates and is considered as a very seismically active one. Through cross-correlating the vertical components of ambient seismic noise registered at four broadband stations in TdF, we were able to extract Rayleigh waves which were used to estimate group velocities in the period band of 2.5-16 s using a timefrequency analysis. Although ambient noise sources are distributed in homogeneously, robust empirical Green＇s functions could be recovered from the cross-correlation of 12 months of ambient noise, The observed group velocities were inverted considering a non-linear iterative damped least-squares inversion procedure and several 1-D shear wave velocity models of the upper crust were *** to the inversion results, the S-wave velocity ranges between 1.75 and 3,7 km/s in the first10 km of crust, depending on the pair of stations considered. These results are in agreement to the major known surface and sub-surface geological and tectonic features known in the area. This study represents the first ambient seismic noise analysis in TdF in order to constraint the upper crust beneath this *** can also be considered as a successful feasibility study for future analyses with a denser station deployment for a more detailed imaging of structure.

关键词： Ambient seismic noise cross-correlation Rayleigh wave dispersion Upper crust Tierra del Fuego

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Animal lectins : a functional view / edited by gerardo R. Vasta, Hafiz Ahmed.

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2009年

作者： edited by gerardo R. Vasta Hafiz Ahmed.

Includes bibliographical references and index.

ISBN: (纸本)9780849372698

Includes bibliographical references and index.

关键词： Lectins.

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Helminth parasites of freshwater fishes from Cuatro Ciénegas,Coahuila,in the Chihuahuan Desert of Mexico:inventory and biogeographical implications

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Integrative Zoology 2014年第3期9卷 328-339页

作者： Rogelio AGUILAR-AGUILAR Andrés MARTÍNEZ-AQUINO Héctor ESPINOSA-PÉREZ gerardo PÉREZ-PONCE DE LEÓN Comparative Biology Department National Autonomous University of MexicoMexico CityMexico Laboratory of Helminthology National Autonomous University of MexicoMexico CityMexico Graduate Program in Biological Sciences National Autonomous University of MexicoMexico CityMexico National Collection of Fish National Autonomous University of MexicoMexico CityMexico

As part of an ongoing inventory of the helminth parasites of freshwater fishes in Mexico, 570 individual fish were collected between Apr 2008 and Oct 2011 in 26 localities along the Cuatro Ciénegas region in Coahuila State, northern Mexico. Seventeen species of hosts, mostly corresponding to Nearctic freshwater elements, were studied. A total of 8324 individual worms were collected during this survey, representing 25 species of helminths, of which 9 were digeneans, 3 monogeneans, 3 acanthocephalans, 9 nematodes and 1 cestode. Most of the records in this checklist represent new host or locality records. The information provided in this checklist may be helpful for our understanding of the biodiversity and historical biogeography of this host-parasite system, because in the Cuatro Ciénegas region occur a Nearctic freshwater fish fauna, along with Neotropical and endemic elements, and from a biogeographical point of view, this may represent a transitional area.

关键词： Acanthocephala Cestoda Cuatro Ciénegas Digenea freshwater fish Mexico Monogenea Nematoda

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Diversity, Endemism and Conservation of Ferns(Polypodiales) in the Mexican Mountain Component

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Journal of Mountain Science 2015年第4期12卷 891-904页

作者： SANGINéS-FRANCO Celia LUNA-VEGA Isolda CONTRERAS-MEDINA Raúl ESPINOSA David TEJERO-DíEZ José Daniel RIVAS gerardo Laboratorio de Biogeografía y Sistemática Departamento de Biología Evolutiva Facultad de Ciencias Universidad Nacional Autónoma de México (UNAM) Escuela de Ciencias Universidad Autónoma "Benito Juárez" de Oaxaca (UABJO) Av.Universidad s/n Ex Hacienda de Cinco Se?ores Oaxaca de Juárez CP 68120 Oaxaca México Facultad de Estudios Superiores Zaragoza Unidad Multidisciplinaria de Investigación Experimental ZaragozaUniversidad Nacional Autónoma de México (UNAM) Carrera de Biología Facultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México MéxicoAvenida de los Barrios Número 1 Colonia Los Reyes Iztacala Tlalnepantla CP 54090 Estado de México México Laboratorio de Biogeografía Acuática Departamento de Biología Comparada Facultad de Ciencias Universidad Nacional Autónoma de México (UNAM)

We analyzed the distributional patterns of95 selected species of leptosporangiate ferns inhabiting the Mexican Mountain Component, using grid-cells of one geographical degree as unit areas,applying endemism indices and richness and beta diversity *** data were obtained from several herbaria and specialized *** grid-cells appear to be important for fern species richness, as they contain 35 to 49 *** gridcells are located in the Sierra Madre Oriental(SMO),Trans-Mexican Volcanic Belt(TMVB) and the Sierra Madre del Sur(SMS).Mean richness by latitudinal belts of one degree showed that the belts with highest values are related to the TMVB and SMS.A total of 13grid-cells were recognized as important from theperspective of endemism; most of them are located also in the SMO, TMVB and *** richest gridcells coincided with one of the main centres of endemism for ferns obtained in this study, located in the convergence of the southern part of the SMO, the eastern portion of the TMVB and the northern part of the SMS, reflecting the high humidity existing on the mountain slopes facing the Gulf of *** important grid-cells recognized from richness and endemism analyses coincide with Mexican Natural Protected *** beta diversity analysis showed a low degree of similarity among grid-cells, implying a high species replacement, as the result of environmental heterogeneity occurring in the Mexican mountain *** the other hand, the spatial analysis suggested a pattern of phytogeographical regionalization comprising twomain areas: the Mexican Transition Zone and the Mexican Central *** play an important role in the Mexican biodiversity and contributing to the beta diversity of Mexico.

关键词： Biogeography Distributional patterns Leptosporangiate ferns Mexico

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Phase equilibrium modelling of the amphibolite facies metamorphism in the Yelapa-Chimo Metamorphic Complex, Mexico

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Geoscience Frontiers 2021年第1期12卷 293-312页

作者： Fabian Gutierrez-Aguilar Peter Schaaf Gabriela Solís-Pichardo gerardo F.Arrieta-García Teodoro Hernandez-Trevino Carlos Linares-Lopez Posgrado en Ciencias de la Tierra Instituto de GeofísicaUniversidad Nacional Autonoma de MexicoAv.Universidad 3000Ciudad de Mexico04510Mexico Laboratorio Universitario de Geoquímica Isotopica(LUGIS) Instituto de GeofísicaUniversidad Nacional Autonoma de MexicoAv.Universidad 3000Ciudad de Mexico04510Mexico Laboratorio Universitario de Geoquímica Isotopica(LUGIS) Instituto de GeologíaUniversidad Nacional Autonoma de MexicoAv.Universidad 3000Ciudad de Mexico04510Mexico Instituto de Geofísica Universidad Nacional Autonoma de MexicoAv.Universidad 3000Ciudad de Mexico04510Mexico

The Yelapa-Chimo Metamorphic Complex forms part of the Jalisco Block in western Mexico and exposes a wide range of Early Cretaceous metamorphic rocks;such as paragneiss,orthogneiss,amphibolites,and ***,the pressure-temperature(P-T)conditions of metamorphism and partial melting remain poorly studied in the *** elucidate metamorphic P-T conditions,phase equilibrium modelling was applied to two sillimanite-garnet paragneisses,one amphibole-orthogneiss,and one ***-garnet paragneisses exhibit a lepidoblastic texture with a biotite+sillimanite+kyanite+garnet+quartz+plagioclase+K-feldspar mineral ***-orthogneiss and amphibolite display a nematoblastic texture with an amphibole+(1)plagioclase+quartz+(1)titanite assemblage and an amphibole+(2)plagioclase+(2)titanite+ilmenite retrograde mineral *** calculated for the two sillimanite-garnet paragneiss samples show P-T peak conditions at~6-7.5 kbar and~725-740℃.The results for amphibole-orthogneiss and the amphibolite yield P-T peak conditions at~8.5-10 kbar and~690-710℃.The mode models imply that metasedimentary and metaigneous units can produce up to~20 vol%and~10 vol%of melt,*** within a closed system during isobaric heating suggests that melt compositions of metasedimentary and metaigneous units are likely to have direct implications for the petrogenesis of the Puerto Vallarta *** new data indicate that the Yelapa-Chimo Metamorphic Complex evolved through a metamorphic gradient between~23-33℃km^-1and the metamorphic rocks formed at depths between~22 km and~30 km with a burial rate of~2.0 km Ma^-***,the P-T data for both metasedimentary and metaigneous rocks provide new constraints on an accretionary framework,which is responsible for generating metamorphism and partial melting in the YelapaChimo Metamorphic Complex during the Early Cretaceous.

关键词： Phase equilibrium modelling Yelapa-Chimo Metamorphic Complex Amphibolite facies Partial melting

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Timing of Proterozoic magmatism in the Sunsas belt, Bolivian Precambrian Shield, SW Amazonian Craton

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Geoscience Frontiers 2021年第6期12卷 277-293页

作者： Ingrid M.Nedel Reinhardt A.Fuck Amarildo S.Ruiz gerardo R.Matos-Salinas Alanielson da C.D.Ferreira Instituto de Geociências Universidade de Brasília(UnB)Brasília-DFBrazil Faculdade de Geociências Universidade Federal de Mato GrossoCuiabá-MTBrazil Instituto de Investigaciones Geológicas y del Medio Ambiente Universidad Mayor de San Andrés(UMSA)Pabellón GeologíaCalle 27Campus Universitario Cota CotaLa PazBolivia Department of Earth Sciences Stellenbosch UniversityPrivate Bag X1Matieland7602 StellenboschSouth Africa

We present new U–Pb zircon and monazite ages from the Sunsas belt granitic magmatism in Bolivia, SW Amazonian Craton. The geochronological results revealed four major magmatic events recorded along the Sunsas belt domains. The older igneous event formed a granitic basement coeval to the Rio Apa Terrane(1.95–1.85 Ga) in the southern domain. The second magmatic episode is represented by 1.68 Ga granites associated to the Paraguá Terrane(1.69–1.66 Ga) in the northern domain. The 1.37–1.34 Ga granites related to San Ignacio orogeny represent the third and more pervasive magmatic event, recorded throughout the Sunsas belt. Moreover, magmatic ages of ~1.42 Ga revealed that the granitogenesis associated to the Santa Helena orogeny also affected the Sunsas belt, indicating that it was not restricted to the Jauru Terrane. Lastly, the 1.10–1.04 Ga youngest magmatism was developed during the Sunsas orogeny and represents the final magmatic evolution related to Rodinia assembly. Likewise, the 1.95–1.85 and 1.68 Ga inherited zircon cores obtained in the ~1.3 Ga and 1.0 Ga granite samples suggest strong partial melting of the Paleoproterozoic sources. The 1079 ± 14 Ma and 1018 ± 6 Ma monazite crystallization ages can be correlated to the collisional tectono-thermal event of the Sunsas orogeny, associated to reactions of medium-to high-grade metamorphism. Thus, the Sunsas belt was built by heterogeneous 1.95–1.85 Ga and 1.68 Ga crustal fragments that were reworked at 1.37–1.34 Ga and 1.10–1.04 Ga related to orogenic collages. Furthermore, the 1.01 Ga monazite age suggests that granites previously dated by zircon can bear evidence of a younger thermal history. Therefore, the geochronological evolution of the Sunsas belt may have been more complex than previously thought.

关键词： SW Amazonian Craton Sunsas belt U–Pb geochronology Zircon Monazite

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The Rational Man Model in Social and Political Studies： A Plea for Relevance

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Journal of Literature and Art Studies 2015年第1期5卷 86-92页

作者： gerardo M. Acay Missouri Valley College Marshall Missouri USA

This paper examines the assumptions of the Rational Man （RM） model familiar in social and political studies. It is observed that the model is too restrictive in its explaining events and behavior in social and political situations. It is suggested that the assumptions of RM model should be relaxed using the familiar methods and techniques of elementary formal logic. The concept of relevance is then introduced to take account of a ＂weaker＂ formal requirement in an attempt to explain events and processes in human action and/or behavior. The concept of ＂justification by reasons＂ is then introduced as a necessary though not sufficient requirement of explaining events and processes in social and political studies

关键词： rational model logic quantifiers relevance justification

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Intestinal amyloidosis:Two cases with different patterns of clinical and imaging presentation

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World Journal of Gastroenterology 2010年第20期16卷 2566-2570页

作者： Pier Paolo Mainenti Sabrina Segreto Marcello Mancini Antonio Rispo Immacolata Cozzolino Stefania Masone Ciro Roberto Rinaldi gerardo Nardone Marco Salvatore IBB CNR NaplesVia Pansini 580131NaplesItaly Department of Biomorphological and Functional Sciences Section of RadiologyUniversity of Naples"Federico II"Via Pansini 580131NaplesItaly Department of Gastro-enterology University of Naples"Federico II"Via Pansini 580131NaplesItaly Department of Biomorphological and Functional Sciences Section of PathologyUniversity of Naples "Federico II"Via Pansini 580131NaplesItaly Department of General Surgery Geriatry and EndoscopyUniversity of Naples"Federico II"Via Pansini 580131NaplesItaly Department of Biotechnology Haema-tology UnitUniversity of Naples"Federico II"Via Pansini 580131NaplesItaly

The involvement of the small bowel in systemic forms of amyloidosis may be diffuse or very rarely *** cases of focal amyloidomas of the duodenum and jejunum without extraintestinal manifestations have been *** focal amyloidomas consisted of extensive amyloid infiltration of the entire intestinal wall *** barium studies,ultrasound and computed tomography(CT)patterns of diffuse small bowel amyloidosis have been described:the signs are non-specific and may include small-bowel dilatation,symmetric bowel wall thickening,mesenteric infiltration,and mesenteric *** data are available about the positron emission tomography (PET)/CT and magnetic resonance imaging(MRI)patterns of intestinal *** report two cases of small bowel amyloidosis:the former characterized by focal deposition of amyloid proteins exclusively within blood vessel walls of the terminal ileum,the latter characterized by diffuse intestinal involvement observed on MRI and PET/CT studies.

关键词： Amyloidosis Small bowel Positron emission tomography/computed tomography Magnetic resonance imaging Computed tomography

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