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Fle.ible.ultra-thin supe.-re.olution e.doscopy

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Scie.ce.China(Physics,Me.hanics & Astronomy) 2024年第3期67卷 171-172页

作者： george S.D.Gordon De.artme.t of e.e.trical and e.e.tronic e.gine.ring University of NottinghamNottingham NG7 2RDUK

In re.e.t ye.rs, multimode.fibe.(MMF) has be.ome.an important tool for high-re.olution e.doscopic imaging in narrow channe.s(e.g., in the.brain via ne.dle. or inside.blood ve.se.s) due.to its high mode.de.sity and fine.diame.e., typically e.e., a major obstacle.to wide.pre.d de.loyme.t in applications is that re.listic pe.turbations, including be.ding, twisting and change. in te.pe.ature. cause.unacce.table.image.de.radation.

关键词： fibe. re.olution typically

Bulk ge.che.istry,Rb-Sr,Sm-Nd,and stable.O-H isotope.syste.atics of the.Me.zime.in high-grade.iron ore.de.osit,Mbalam iron ore.district,southe.n Came.oon

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Acta Ge.chimica 2024年第4期43卷 677-706页

作者： Samndong Cyril Tufoin Che. e.manue. Suh Tabod Charle. Tabod george Le.e.ihbwe. Ngiamte De.artme.t of Ge.logy Mining and Environmental ScienceThe University of BamendaB.P.39BambiliNorth West RegionCameroon e.onomic Ge.logy Unit Department of GeologyUniversity of BueaP.O.63BueaSouth West RegionCameroon De.artme.t of Physics Faculty of ScienceThe University of BamendaB.P.39BambiliNorth West RegionCameroon De.artme.t of Ge.logy Pan-African University Life and Earth Sciences Institute(PAULESI)University of IbadanIbadanNigeria

Bulk ge.che.istry,Sr,Nd,and O-H isotope.syste.atics are.re.orte. for the.first time.on bande. iron formation(BIF)-hoste. high-grade.iron ore.at the.northwe.te.n se.me.t of Congo Craton(CC).Locate. in Mbalam iron ore.district,Southe.n Came.oon,Me.zime.in iron ore.de.osit is a he.atite.magne.ite.BIF syste.,dominate. by SiO_(2)+Fe.(2)O_(3)(97.1 to 99.84 wt%),with low conce.trations of clastic e.e.e.ts e.g.,Al_(2)O_(3),TiO_(2),and HFSe.de.icting a ne.rly pure.che.ical *** Re.+Y signature.of the.iron de.osit displays strong positive.e. anomaly,strong ne.ative.Ce.anomaly,and chondritic to supe.chondritic Y/Ho ratios,sugge.tive.of formation by mixe. se.wate.-high te.pe.ature.hydrothe.mal fluids in oxidising ***^(87)Sr/^(86)Sr ratios of the.BIF are.highe. than the.maximum^(87)Sr/^(86)Sr e.olution curve. for all Arche.n re.e.voirs(bulk silicate.e.rth,Arche.n crust and Arche.n se.wate.),indicating involve.e.t of contine.tally-de.ive. compone.ts during BIF formation and ***Ɛ_(Nd)(t)(+2.26 to+3.77)and Nd mode. age.indicate.that che.ical constitue.ts for the.BIF we.e.de.ive. from undiffe.e.tiate. crustal source.be.we.n 3.002 and 2.88 *** variable.and dive.se.O and H isotope.data(−1.9‰to 17.3‰and−57‰to 136‰re.pe.tive.y)indicate.that the.Me.zime.in iron ore.forme. initially from magmatic plume. and late. e.riche. by magmatic-me.amorphic-modifie. me.e.ric *** balance.calculations indicate.mine.alisation by combine. le.ching and pre.ipitation,with an ave.age.iron e.richme.t factor of>2.67 and SiO_(2)de.le.ion factor of>*** is associate. with an ove.all volume.re.uction of 28.27%,re.le.ting ne. le.ching and volume.collapse.of the.BIF protholith.

关键词： Bulk ge.che.istry Rb-Sr Sm-Nd Mitzime.in High-grade.iron ore

Se.tic cardiomyopathy phe.otype.in the.critically ill may de.e.d on antimicrobial re.istance

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Journal of Inte.sive.Me.icine 2024年第3期4卷 355-361页

作者： Vasiliki Tsolaki Kyriaki Parisi george e.Zakynthinos e.rosini Ge.ovasile.ou Nikitas Karavidas Vassile.os Vazgiourakis e.aminondas Zakynthinos De.osthe.e. Makris Inte.sive.Care.Unit University Hospital of LarissaUniversity of Thessaly Faculty of MedicineLarissaGreece Third Cardiology Clinic University of AthensSotiria HospitalAthensGreece Re.piratory De.artme.t University Hospital of LarissaUniversity of Thessaly Faculty of MedicineLarissaGreece

Background Se.sis is a life.thre.te.ing organ dysfunction,and se.tic cardiomyopathy(SCM)may complicate.the.course.of the.*** with multidrug-re.istant(MDR)pathoge.s has be.n linke. with worse.*** study aims to e.aluate.SCM in patie.ts with infe.tions cause. by diffe.e.t antimicrobial-re.istant *** This re.rospe.tive.study include. patie.ts with se.sis/se.tic shock,hospitalize.,and intubate. in the.inte.sive.care.unit of the.Unive.sity Hospital of Larissa be.we.n January 2022 and Se.te.be. 2023 with e.hocardiographic data during the.first two days afte. infe.tion *** patie.ts we.e.divide. into two groups:non-MDR-SCM group and MDR-SCM *** cardiac function was compare. be.we.n the.two *** A total of 62 patie.ts we.e.include. in the.***-four patie.ts comprise. the.MDR-SCM and 18 the.non-MDR-SCM ***-six patie.ts(41.9%)pre.e.te. with le.t ve.tricular(LV)systolic dysfunction,and≤35%right ve.tricular fractional are. change.RVFAC)was pre.e.t in 56.4%.LV systolic function was more.se.e.e.y impaire. in the.non-MDR-SCM group(le.t ve.tricular e.e.tion fraction,35.8%±4.9%vs.45.6%±2.4%,P=0.049;LV outflow tract ve.ocity time.inte.ral,[10.1±1.4]cm vs.[15.3±0.74]cm,P=0.001;LV-Strain,–9.02%±0.9%vs.–14.02%±0.7%,P=0.001).The.MDR-SCM group pre.e.te. with more.se.e.e.right ve.tricular(RV)dilatation(right ve.tricular e.d-diastolic are./le.t ve.tricular e.d-diastolic are.,0.81±0.03 vs.0.7±0.05,P=0.042)and worse.RV systolic function(RVFAC,32.3%±1.9%vs.39.6%±2.7%,P=0.035;tricuspid annular plane.systolic e.cursion,[15.9±0.9]mm vs.[18.1±0.9]mm,P=0.165;systolic tissue.Dopple. ve.ocity me.sure. at the.late.al tricuspid annulus,[9.9±0.5]cm/s vs.[13.1±0.8]cm/s,P=0.002;RV-strain,–11.1%±0.7%vs.–15.1%±0.9%,P=0.002).Conclusion SCM re.ate. to MDR infe.tion pre.e.ts with RV systolic dysfunction pre.ominance.while.non-MDR-SCM is mainly de.icte. with LV systolic dysfunction impairme.t.

关键词： Se.tic cardiomyopathy Multidrug-re.istant pathoge. Le.t ve.tricular failure Right ve.tricular dysfunction Le.t/right ve.tricular longitudinal strain Ve.triculoarte.ial Coupling

Multifunctional nanoparticle.me.iate. combining the.apy for human dise.se.

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Signal Transduction and Targe.e. The.apy 2024年第2期9卷 343-375页

作者： Xiaotong Li Xiuju Pe.g Makhloufi Zoulikha george Frimpong Boafo Koshe.i Thapa Magar Yanmin Ju We. He School of Pharmacy China Pharmaceutical UniversityNanjing 2111198PR China Xiangya School of Pharmace.tical Scie.ce. Central South UniversityChangsha 410013PR China Shanghai Skin Dise.se.Hospital Tongji University School of MedicineShanghai 200443China

Combining e.isting drug the.apy is e.se.tial in de.e.oping ne. the.ape.tic age.ts in dise.se.pre.e.tion and *** pre.linical inve.tigations,combine. e.fe.t of ce.tain known drugs has be.n we.l e.tablishe. in tre.ting e.te.sive.human *** to syne.gistic e.fe.ts by targe.ing various dise.se.pathways and advantage.,such as re.uce. administration dose.de.re.se. toxicity,and alle.iate. drug re.istance.combinatorial tre.tme.t is now be.ng pursue. by de.ive.ing the.ape.tic age.ts to combat major clinical illne.se.,such as cance.,athe.oscle.osis,pulmonary hype.te.sion,myocarditis,rhe.matoid arthritis,inflammatory bowe. dise.se.me.abolic disorde.s and ne.rode.e.e.ative.*** the.apy involve. combining or co-de.ive.ing two or more.drugs for tre.ting a spe.ific ***(NP)-me.iate. drug de.ive.y syste.s,i.e.,liposomal NPs,polyme.ic NPs and nanocrystals,are.of gre.t inte.e.t in combinatorial the.apy for a wide.range.of disorde.s due.to targe.e. drug de.ive.y,e.te.de. drug re.e.se.and highe. drug stability to avoid rapid cle.rance.at infe.te. *** re.ie. summarize. various targe.s of dise.se.,pre.linical or clinically approve. drug combinations and the.de.e.opme.t of multifunctional NPs for combining the.apy and e.phasize. combinatorial the.ape.tic strate.ie. base. on drug de.ive.y for tre.ting se.e.e.clinical ***,we.discuss the.challe.ging of de.e.oping NP-code.ive.y and translation and provide.pote.tial approache. to addre.s the.*** re.ie. offe.s a compre.e.sive.ove.vie. for re.e.t cutting-e.ge.and challe.ging in de.e.oping NP-me.iate. combination the.apy for human dise.se..

关键词： drugs dise.se. pre.e.tion

A Lite.ature.Re.ie.: Pote.tial e.fe.ts That He.lth Apps on Mobile.De.ice. May Have.on Patie.t Privacy and Confide.tiality

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e.He.lth Te.e.ommunication Syste.s and Ne.works 2024年第3期13卷 23-44页

作者： Anna She.i george Jomin george Judy Je.kins Faculty of Me.icine.and He.lth Life.Scie.ce. Swansea University Swansea UK

Purpose. This re.e.rch aims to e.aluate.the.pote.tial thre.ts to patie.t privacy and confide.tiality pose. by mHe.lth applications on mobile.de.ice.. Me.hodology: A compre.e.sive.lite.ature.re.ie. was conducte., se.e.ting e.ghty-e.ght article. publishe. ove. the.past fifte.n ye.rs. The.study asse.se. data gathe.ing and storage.practice., re.ulatory adhe.e.ce. le.al structure., conse.t proce.ure., use. e.ucation, and strate.ie. to mitigate.risks. Re.ults: The.findings re.e.l significant advance.e.ts in te.hnologie. de.igne. to safe.uard privacy and facilitate.the.wide.pre.d use.of mHe.lth apps. Howe.e., pe.siste.t e.hical issue. re.ate. to privacy re.ain large.y unchange. de.pite.the.e.te.hnological stride..

关键词： Mobile.De.ice. Patie.t Privacy Confide.tiality Bre.che. Data Se.urity Data Prote.tion Re.ulatory Compliance Use. Conse.t Data e.cryption Third-Party Inte.ration Use. Aware.e.s

A Re.e.ling Voyage.Visit to China dispe.s mispe.ce.tions,shows the.re.l picture.of China-Africa frie.dship

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ChinAfrica 2024年第9期16卷 62-63页

作者： george MUSIIMe De.e.opme.t Watch Ce.tre Nigeria

It is ve.y e.sy for an African living in Africa to be.misle. into be.ie.ing that the.China-Africa frie.dship is *** fact,with so much of information re.ching Africa about China-Africa coope.ation be.ng targe.e. at unde.mining the.frie.dly re.ations e.joye. by the.two side. and the.e.orts to build a China-Africa community with a share. future.this in a way is not surprising.

关键词： Africa supe.ficial frie.ds

Rocahe.e.irus ratti: An unde.re.ognise. cause.of acute.he.atitis

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World Journal of He.atology 2024年第8期16卷 1084-1090页

作者： george S Ghe.lan De.artme.t of Infe.tious Dise.se. “Carol Davila”University of Medicine and PharmacyBucharest 050474Romania

Zoonose. are.re.ponsible.for many of all e.e.ging infe.tious dise.se. as we.l as for those.alre.dy *** ratti is a rat-originate. virus re.ate. to the.he.atitis e.virus(Paslahe.e.irus balayani)but highly dive.ge.t ge.e.ically from this,with a high cross-spe.ie. infe.tion pote.tial and zoonotic *** can infe.t humans,le.ding to acute.he.atitis,and is primarily transmitte. through the.consumption of contaminate. *** ratti was first discove.e. in Ge.many in *** first human case.was de.cribe. in 2017 in Hong Kong in an immune.compromise. *** first case.of chronic infe.tion with Rocahe.-e.irus ratti was de.cribe. in 2023.A me.a-analysis base. on 38 studie. publishe. be.we.n 2000 and 2023 ide.tifie. 21 case. in humans de.cribe. up to this date.and 489 infe.tions in diffe.e.t *** aware.e.s re.arding this virus is e.se.tial,as the.e.are.probably many case. that re.ain undiagnose.,and the.virus e.e. has the.ability to produce.chronic infe.tions in se.e.te. patie.ts.

关键词： He.atitis Rocahe.e.irus ratti Rats Zoonose. He.e.iridae Live.

Fe.ding be.avior and hormoligosis associate. with imidacloprid re.istance.in Asian citrus psyllid,Diaphorina citri

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Inse.t Scie.ce 2024年第4期31卷 1211-1221页

作者： Xue.Dong Che. Justin george Laure. M.Die.e.brock Hunte. Gosse.t Guoping Liu Jawwad A.Qure.hi Lukasz L.Ste.inski e.tomology and Ne.atology De.artme.t University of FloridaCitrus Research and Education CenterLake AlfredFloridaUSA Southe.n Inse.t Manage.e.t Re.e.rch Unit USDA-ARSStonevilleMississippiUSA e.tomology and Ne.atology De.artme.t University of FloridaSouthwest Florida Research and Education CenterImmokaleeFloridaUSA

Imidacloprid is a ne.nicotinoid inse.ticide.use. for managing the.Asian citrus psyllid,Diaphorina citri Kuwayama,which se.ve. as ve.tor of phytopathoge.s causing citrus ***,de.e.opme.t of re.istance.to ne.nicotinoids among populations of *** has coincide. with occasional control failure. in the.*** obje.tive. of this re.e.rch we.e.to(1)surve. curre.t le.e.s of imidacloprid re.istance.in Florida citrus;(2)compare.fe.ding be.avior be.we.n imidacloprid-re.istant and susce.tible.*** using e.e.trical pe.e.ration graph re.ordings,and(3)inve.tigate.the.possible.amplification of inse.ticide.hormoligosis associate. with *** surve.s confirme. that the.susce.tibility of *** populations to imidacloprid has de.re.se. in comme.cial Florida citrus grove. compare. with a laboratory-susce.tible.*** 12 ge.e.ations of se.e.tion,re.istance.to imidacloprid incre.se. by 438 fold compare. with the.susce.tible.***-susce.tible.*** fe.ding on citrus e.hibite. significantly more.bouts associate. with inte.ce.lular pathway(C),phloe. pe.e.ration(D),phloe. salivation(e.),and nonprobing(Np)activitie. than imidacloprid-re.istant ***,the.e.we.e.no diffe.e.ce. obse.ve. in the.fre.ue.cy or duration of phloe. inge.tion or xyle. fe.ding be.we.n susce.tible.and re.istant *** was no statistical diffe.e.ce.in fe.undity be.we.n re.istant and susce.tible.***,the.fe.undity of imidacloprid-susce.tible.fe.ale.*** tre.te. with a suble.hal conce.tration of imidacloprid(LC_(25))incre.se. significantly compare. with controls,while.such hormoligosis was le.s pronounce. among imidacloprid-re.istant *** re.ults sugge.t that imidacloprid-re.istant psyllids may ce.se.fe.ding soone. than susce.tible.counte.parts following suble.hal e.posure.to this inse.ticide.indicative.of a be.avioral re.istance.me.hanism.

关键词： artificial se.e.tion e.e.trical pe.e.ration graph fe.ding be.avior hormoligosis inse.ticide.re.istance suble.hal e.posure

De.ormations at e.rth’s dayside.magne.opause.during quasi-radial IMF conditions:Global kine.ic simulations and Soft X-ray Imaging

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e.rth and Plane.ary Physics 2024年第1期8卷 59-69页

作者： ZhongWe. Yang RiKu Jarvine. XiaoChe.g Guo TianRan Sun Dimitra Koutroumpa george K.Parks Can Huang BinBin Tang QuanMing Lu Chi Wang State.Ke. Laboratory of Space.We.the. National Space Science CenterChinese Academy of SciencesBeijing 100190China Finnish Me.e.rological Institute FI-00101 HelsinkiFinland LATMOS/IPSL CNRSUVSQ UniversitéParis-SaclaySorbonne UniversitéGuyancourt78280France Space.Scie.ce. Laboratory University of CaliforniaBerkeleyCalifornia 94720USA CAS e.gine.ring Laboratory for De.p Re.ource. e.uipme.t and Te.hnology Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029 China De.p Space.e.ploration Laboratory/School of e.rth and Space.Scie.ce. University of Science and Technology of ChinaHefei 230026China

The.Solar wind Magne.osphe.e.Ionosphe.e.Link e.plore.(SMILe.is a joint mission of the.e.rope.n Space.Age.cy(e.A)and the.Chine.e.Acade.y of Scie.ce.(CAS).Primary goals are.inve.tigating the.dynamic re.ponse.of the.e.rth's magne.osphe.e.to the.solar wind(SW)impact via simultane.us in situ magne.oshe.th plasma and magne.ic fie.d me.sure.e.ts,X-Ray image. of the.magne.oshe.th and magne.ic cusps,and UV image. of global auroral *** de.ormations associate. with magne.oshe.th high spe.d je.s(HSJs)unde. a quasi-paralle. inte.plane.ary magne.ic fie.d condition are.studie. using a thre.dime.sional(3-D)global hybrid *** X-ray inte.sity calculate. base. on both physical quantitie. of solar wind proton and oxyge. ions is *** obtain ke. findings conce.ning de.ormations at the.magne.opause.(1)Magne.opause.de.ormations are.highly cohe.e.t with the.magne.oshe.th HSJs ge.e.ate. at the.quasi-paralle. re.ion of the.bow shock,(2)X-ray inte.sitie. e.timate. using solar wind h+and se.f-consiste.tO7+ions are.consiste.t with e.ch othe.,(3)Visual space.raft are.e.ploye. to che.k the.discrimination ability for capturing magne.opause.de.ormations on Lunar and polar orbits,*** SMILe.space.raft on the.polar orbit could be.e.pe.te. to provide.opportunitie. for capturing the.global ge.me.ry of the.magne.opause.in the.e.uatorial plane.A striking point is that SMILe.has the.pote.tial to capture.small-scale.magne.opause.de.ormations and magne.oshe.th transie.ts,such as HSJs,at me.ium altitude. on its *** re.ults also de.onstrate.that a lunar base. image.(e.g.,Lunar e.vironme.t he.iosphe.ic X-ray Image.,Le.I)is e.pe.te. to obse.ve.a localize. brighte.ing of the.magne.oshe.th during HSJ e.e.ts in the.me.idian *** pre.iminary re.ults might contribute.to the.pre.studie. for the.SMILe.and Le.I missions by providing qualitative.and quantitative.soft X-ray e.timate. of dayside.kine.ic proce.se..

关键词： collisionle.s shock SMILe.mission fore.hock