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Pharmacological Overview of Tinospora cordifolia, an Ethnologically Important Plant of Bangladesh

Pharmacology & Pharmacy 2022年第3期13卷 93-106页

作者： gazi monjur murshid Sukalyan Kumar Kundu Md. Hossain Sohrab Md. Abdul Mazid Department of Pharmaceutical Chemistry University of Dhaka Dhaka Bangladesh Department of Pharmacy Jahangirnagar University Dhaka Bangladesh Pharmaceutical Sciences Research Division Bangladesh Council of Scientific and Industrial Research Dhaka Bangladesh

Tinospora cordifolia (Wild) Hook, local name: Guduchi/Amrita;English: Indian Tinospora, Hindi: Giloya/Gulancha, belongs to the family of Menispermaceae and is found in abundance in Bangladesh, Myanmar, Sri Lanka, and China, the plant is a spreading and mounting shrub with a lot twisting branches. T. cordifolia is used in Ayurveda medicinal system and has numerous therapeutic properties. This article summarizes the chemical constituents and pharmacological properties found within the plant. The review will provide a scientific basis of its use in Ayurveda and is an informative database on an ethno-pharmacologically important medicinal plant for future researchers.

关键词： Tinospora cordifolia Ethnopharmacology Chemical Constituents Biological Activities

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Phytopharmacological evaluation of ethanol extract of Sida cordifolia ***

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Asian Pacific Journal of Tropical Biomedicine 2014年第1期4卷 18-24页

作者： Mohammad Abdul Motalib Momin Sm Faysal Bellah Sarder Mohammad Raussel Rahman Ahmed Ayedur Rahman gazi Mohammad monjur murshid Sarder Mohammad Saker Billah Talha Bin Emran Department of Pharmacy Jahangirnagar University Department of Clinical Pharmacy and Pharmacology Dhaka University Pharmacy Discipline Life Science SchoolKhulna University Department of Chemistry Gort.M.M.University College Department of Pharmacy BGC Trust University

Objective:To investigate the phytochemical screening(group determination)and selected pharmacological activities(antioxidant,antimicrobial and analgesic activity)of the plant Sida cordifolia Linn(***).Methods:Eighty percent concentrated ethanol extract of the roots was *** identify the chemical constituents of plant extract standard procedures were *** phytochemical screening the crude extract was tested for the presence of different chemical groups like reducing sugar,tannins,saponins,steroids,flavonoids,gums,alkaloids and *** antioxidant property of ethanolic extract of *** was assessed by DPPH free radical scavenging *** activity of the extract was tested using the model of acetic acid induced writhing in *** sodium is used as reference standard drug for the analgesic activity test Antibacterial activity of plant extract was carried out using disc diffusion method with five pathogenic bacteria comparison with kanamycin as a ***:Phytochemical analysis of the ethanolic extract of the roots of *** indicated the presence of reducing sugar,alkaloids,steroids and *** DPPH scavenging assay the IC_(50)value was found to be 50 ug/mL which was not comparable to the standard ascorbic *** crude extract produced 44.3%inhibition of writhing at the dose of 300 mg/kg body weight which is statistically significant(P>0.001).The in vitro antimicrobial activity of the ethanol extract of the roots of *** showed no antimicrobial activity against five types of *** experiment was conducted only with five species of bacteria as test species,which do not at all indicate the total inactivity against ***:The obtained results provide a support for the use of this plant in traditional medicine but further pharmacological studies are required.

关键词： Antioxidant Antimicrobial Analgesic DPPH Phytochemical screening

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