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Polymorphisms in the 5 ′ regulatory region of my-ostatin gene are associated with early growth traits in Yorkshire pigs

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science china(Life sciences) 2007年第5期50卷 642-647页

作者： YU LingZhi1, TANG Hui1, wang JiYing2, WU Ying2, ZOU LiLi1, JIANG YunLiang1, WU ChangXin3 & LI Ning4 1 college of Animal science and Veterinary Medicine, Shandong agricultural university, Taian 271018, china 2 Institute of Animal science and Veterinary Medicine, Shandong Academy of agricultural sciences, Jinan 250100, china 3 college of Animal science and Technology, china agricultural university, beijing 100094, china 4 State Key Laboratory for Agro-biotechnology, china agricultural university, beijing 100094, china. college of Animal science and Veterinary Medicine Shandong Agricultural University Taian 271018 China Institute of Animal science and Veterinary Medicine Shandong Academy of Agricultural Sciences Jinan 250100 China college of Animal science and Technology China Agricultural University Beijing 100094 China State Key Laboratory for Agro-biotechnology China Agricultural University Beijing 100094 China

Myostatin is a negative regulator of skeletal muscle *** present studycloned the 5' regulatory region of porcine myostatin gene,screened its polymorphisms and analyzedtheir associations with early growth traits in Yorkshire *** results indicated that a fragmentlength polymorphism and a polymorphism concerning two nucleotide changes exist in the 5' regulatoryregion of porcine myostatin *** sites 435 and 447,allele A and allele B have the haplotypes ofA-G and G-A,*** allelic frequency of B is 0.475 in Yorkshire *** homozygous BBgenotype was detected in 9 Laiwu Black *** B was found to have positive effect on bodyweight on day 21 (BW21) (P1),body weight on day 28 (BW28) (P21 d (ADG1) (P1),average daily gain from birth to 28 d(ADG2) (P21 d to 70 d (ADG3) (P1),*** additiveeffect of allele B on BW21,BW28,BW70,ADG1,ADG2 and ADG3 was 0.596±0.205 kg (P=0.0041),0.498±0.200kg (P=0.0136) 1.409±0.551 kg (P=0.0112),28.39±9.74 g P=0.0041),17.78±7.15 g (P=0.0136) and37.00±16.92 g (P=0.0304),respectively,whereas its effect on average daily gain from 28 d to 70 d(ADG4) was not significant (P>0.1),although BB individuals are superior in average daily gain to AAand AB.

关键词： pig, myostatin, 5' regulatory region, polymorphism, early growth trait

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Simulation and Prediction of Soil Organic Carbon Dynamics in Jiangsu Province Based on Model and GIS Techniques

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Journal of Integrative Agriculture 2003年第9期 67-73页

作者： SHEN Yu 1, HUANG Yao 1,2 , ZONG Liang gang 1, ZHANG Wen 1, XU Mao 3 and LIU Lin wang 3 ( 1college of Resources and Environmental sciences, Nanjing agricultural university, Nanjing 210095, P.R.china 2Institute of Atmospheric Physics, Chinese Academy of sciences, beijing 100029, P.R.china 3Jiangsu agricultural and Forestry Department, Nanjing 210036, P.R.china)

Based on the databases of soils, meteorology, crop production, and agricultural management, changes in the soil organic carbon (SOC) of agro ecosystems in Jiangsu Province were simulated by using a soil organic carbon model with a linkage of GIS. Four data sets of soil organic carbon measured from various field experiments in Jiangsu Province were used to validate the model. It was demonstrated that the model simulation in general agreed with the field measurements. Model simulation indicated that the SOC content in approximately 77% of the agricultural soils in Jiangsu Province has increased since the Second National Soil Survey completed in the early 1980s. Compared with the values in 1985, the SOC content in 2000 was estimated to increase by 1.03.0 g kg 1 for the north and the coastal areas of the province, and by 3.55.0 g kg 1 for the region of Tai Lake in the south. A slight decrease (about 0.51.5 g kg 1 ) was estimated for the central region of Jiangsu Province and the Nanjing Zhenjiang hilly area. Model prediction for 2010 A.D. under two scena rios, i.e., with 30 and 50% of the harvested crop straw incorporation, suggested that the SOC in Jiangsu Province would increase, and thus that the agricultural soils would have potential as organic carbon storage. The incorporation of crop straw into soils is of great benefit to increase soil carbon storage, consequently to benefit the control of the rise of atmospheric CO 2 concentration and to maintain the sustainable development of agriculture.

关键词： Soil Organic carbon Model GIS Jiangsu Province

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Inferring Mycobacterium Tuberculosis Drug Resistance and Transmission using Whole-genome Sequencing in a High TB-burden Setting in china

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Biomedical and Environmental sciences 2024年第2期37卷 157-169页

作者： FAN Yu Feng LIU Dong Xin CHEN Yi wang OU Xi Chao MAO Qi Zhi yang Ting Ting wang Xi Jiang HE Wen Cong ZHAO Bing LIU Zhen Jiang ABULIMITI Maiweilanjiang AIHEMUTI Maimaitiaili gao Qian ZHAO Yan Lin Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS) School of Basic Medical SciencesShanghai Medical CollegeFudan UniversityShanghai 200032China National Tuberculosis Reference Laboratory Chinese Center for Disease Control and PreventionBeijing 102206China Hangzhou Red Cross Hospital Hangzhou 310005ZhejiangChina Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention Urumqi 830026XinjiangChina Tuberculosis Dispensary of Kashgar Prefecture Kashgar 844099XinjiangChina

Objective china is among the 30 countries with a high burden of tuberculosis(TB)worldwide,and TB remains a public health *** Prefecture in the southern Xinjiang Autonomous Region is considered as one of the highest TB burden regions in ***,molecular epidemiological studies of Kashgar are *** A population-based retrospective study was conducted using whole-genome sequencing(WGS)to determine the characteristics of drug resistance and the transmission *** A total of 1,668 isolates collected in 2020 were classified into lineages 2(46.0%),3(27.5%),and 4(26.5%).The drug resistance rates revealed by WGS showed that the top three drugs in terms of the resistance rate were isoniazid(7.4%,124/1,668),streptomycin(6.0%,100/1,668),and rifampicin(3.3%,55/1,668).The rate of rifampicin resistance was 1.8%(23/1,290)in the new cases and 9.4%(32/340)in the previously treated *** resistance mutations were detected more frequently in lineage 2 strains than in lineage 3 or 4 strains,respectively:18.6%vs.8.7 or 9%,P25.9%(432/1,668).Multivariate logistic analyses indicated that sex,age,occupation,lineage,and drug resistance were the risk factors for recent *** the low rate of drug resistance,drug-resistant strains had a higher risk of recent transmission than the susceptible strains(adjusted odds ratio,1.414;95%CI,1.023–1.954;P=0.036).Among all patients with drug-resistant tuberculosis(DR-TB),78.4%(171/218)were attributed to the transmission of DR-TB *** Our results suggest that drug-resistant strains are more transmissible than susceptible strains and that transmission is the major driving force of the current DR-TB epidemic in Kashgar.

关键词： Mycobacterium tuberculosis Whole-genome sequencing(WGS) Transmission Drug resistance Xinjiang

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Study and design of an agricultural SMS system based on a GSM modem

Study and design of an agricultural SMS system based on a GS...

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The First International Conference on Computers and Computing Technologies in Agriculture

作者： GANGHONG ZHANG~(1 2) WANLIN gao~(1 *) XIU wang~2 XINLAN JIANG~1 yang PING~1 HONGQIANG yang~1 1 college of Information and Electrical Engineering china agricultural university No.17 Qinghua Dong Lu Haidian beijing 100083 china 2 National Engineering Research Center for Information Technology in Agriculture beijing 100097 china

＜正＞To allow agricultural information to be quickly and accurately transferred in the field,it is possible to utilise existing agricultural information resources through mobile phone messages transferred to *** paper describes an agricultural SMS system based on a GSM modem and its associated *** purpose of this study is to construct a short message service system that is capable of receiving and sending messages freely in rural areas. For this,we create a buffer queue able to receive and send short ***,we establish a separate data table able to communicate incoming and outgoing information to a higher agricultural information management *** this internet system,agricultural information is extracted;organised and communicated back to the farmer.

关键词： agricultural information ISMG GSM modem SMS

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Climate change reductions in lake ice cover duration and thickness help regulate the carbon sink potential of plateau type lakes

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National science Open 2024年第5期3卷 114-129页

作者： Di Shen Yafeng wang Junjie Jia Shuoyue wang Kun Sun yang gao college of Earth and Environment science Lanzhou UniversityLanzhou 730000China State Key Laboratory of Tibetan Plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China college of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China

Lake ice changes in winter under the influence of global climate change,but how lake ice changes will regulate water gross primary productivity(GPP)and carbon sequestration capacity is still ***,we evaluated and analyzed the geographic spatial pattern and dynamic changes of lake ice and GPP on the Qinghai-Tibetan Plateau(QTP)in the past 20 *** show that lake ice duration on the QTP is 123.36±2.43 d on average,although longer for lakes at higher altitudes,of moderate size,and with shallower *** ice thickness is between 55-66 cm on average,and its GPP on the QTP is between 0.17-3.35 g C m^(-2)d^(-1).In the context of global climate change,reductions in lake ice cover duration and changes in ice thickness on the QTP increased phytoplankton GPP during the winter freeze period while decreasing Carbon dioxide(CO_(2))emissions during the melting period.

关键词： Qinghai-Tibetan Plateau lake ice gross primary productivity carbon sequestration

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Plant regeneration in the new era:from molecular mechanisms to biotechnology applications

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science china(Life sciences) 2024年第7期67卷 1338-1367页

作者： Chunli Chen Yuxin Hu Momoko Ikeuchi Yuling Jiao Kalika Prasad Ying Hua Su Jun Xiao Lin Xu Weibing yang Zhong Zhao Wenkun Zhou Yun Zhou Jian gao Jia-Wei wang National Key Laboratory for Germplasm Innovation&Utilization of Horticultural Crops Hubei Hongshan LaboratoryHuazhong Agricultural UniversityWuhan 430070China college of Life science and Technology Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Plant Molecular Physiology Institute of BotanyChinese Academy of Sciences(CAS)China National Botanical GardenBeijing 100093China Division of Biological sciences Graduate School of Science and TechnologyNara Institute of Science and TechnologyNara 630-0192Japan State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China Peking-Tsinghua Center for Life sciences Center for Quantitative BiologyAcademy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Indian Institute of science Education and Research Pune 411008IndiaThiruvananthapuram 695551India State Key Laboratory of Wheat Improvement College of Life SciencesShandong Agricultural UniversityTai’an 271018China Sino-German Joint Research Center on agricultural Biology Shandong Agricultural UniversityTai’an 271018China Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental Biology(IGDB)CASBeijing 100101China CAS-JIC Centre of Excellence for Plant and Microbial science(CEPAMS) IGDBCASBeijing 100101China National Key Laboratory of Plant Molecular Genetics CEMPSInstitute of Plant Physiology and Ecology(SIPPE)CASShanghai 200032China CEPAMS SIPPECASShanghai 200032China Hefei National Laboratory for Physical sciences at the Microscale CEMPSSchool of Life SciencesDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230027China State Key Laboratory of Plant Environmental Resilience College of Biological SciencesChina Agricultural UniversityBeijing 100193China Department of Botany and Plant Pathology and Center for Plant Biology Purdue UniversityWest Lafayette 47907USA School of Life science and Technology Shang

Plants or tissues can be regenerated through various *** animal regeneration,cell totipotency and pluripotency are the molecular basis of plant *** systematic studies on Arabidopsis thaliana gradually unravel the fundamental mechanisms and principles underlying plant ***,plant hormones,cell division,epigenetic remodeling,and transcription factors play crucial roles in reprogramming somatic cells and reestablishing meristematic *** research on basal non-vascular plants and monocot crops has revealed that plant regeneration differs among species,with various plant species using distinct mechanisms and displaying significant differences in regenerative *** multi-omics studies at the single-cell level,tracking plant regeneration processes in real-time,and deciphering the natural variation in regenerative capacity will ultimately help understand the essence of plant regeneration,improve crop regeneration efficiency,and contribute to future crop design.

关键词： apical meristem model species regeneration phytohormone plant cell reprogramming somatic embryogenesis

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Distribution of Soil Organic Carbon Fractions Along the Altitudinal Gradient in Changbai Mountain,china

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Pedosphere 2011年第5期21卷 615-620页

作者： ZHANG Min ZHANG Xiao-Ke LIANG Wen-Ju JIANG Yong DAI Guan-Hua wang Xu-gao HAN Shi-Jie State Key Laboratory of Forest and Soil Ecology Institute of Applied Ecology Chinese Academy of Sciences Shenyang 110164 (China) Vegetable Research Institute Liaoning Academy of Agricultural Sciences Shenyang 110161 (China) Graduate university of Chinese Academy of sciences Beijing 100049 (China)

Understanding the responses of soil organic carbon(SOC) fractions to altitudinal gradient variation is important for understanding changes in the carbon balance of forest *** our study the SOC and its fractions of readily oxidizable carbon(ROC),water-soluble carbon(WSC) and microbial biomass carbon(MBC) in the soil organic and mineral horizons were investigated for four typical forest types,including mixed coniferous broad-leaved forest(MCB),dark coniferous spruce-fir forest(DCSF),dark coniferous spruce forest(DCS),and Ermans birch forest(EB),along an altitudinal gradient in the Changbai Mountain Nature Reserve in Northeast *** results showed that there was no obvious altitudinal pattern in the *** variation trends of SOC with altitude were observed between the organic and mineral *** differences in the contents of SOC,WSC,MBC and ROC were found among the four forest types and between *** contents of ROC in the mineral horizon,WSC in the organic horizon and MBC in both horizons in the MCB and EB forests were significantly greater than those in either DCSF or DCS *** proportion of soil WSC to SOC was the lowest among the three main *** contents of WSC,MBC and ROC were significantly correlated(P < 0.05) with SOC *** can be concluded that vegetation types and climate were crucial factors in regulating the distribution of soil organic carbon fractions in Changbai Mountain.

关键词： active carbon fractions altitude forest ecosystem Northeast china vegetation type

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Efficacy and safety of transvaginal mesh repair in a cohort with a minimum of 10-year follow-up

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science china(Life sciences) 2024年第5期67卷 1061-1068页

作者： Zhibo Zhang Jianbin Guo Weijie Tian Ye Zhang Yuelun Zhang Tianshu Sun Jiali Duan Xinmiao Bao Yuan wang yang Ye Qianqian gao Honghui Shi Abraham Nick Morse Juan Chen Lan Zhu Departmentof Obstetrics and Gynecology Peking Union MedicalCollege HospitalChinese Academyof Medical Sciences&Peking Union MedicalCollegeNational Clinical Research Center for Obstetricand Gynecologic DiseasesBeijing 100730China Department of Gynecology Guizhou Provincial People’s HospitalMedical College of Guizhou UniversityGuiyang 550002China Department of Obstetrics and Gynecology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450000China Medical Research Center Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Medical Doctor Program Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Department of Pathology Peking Union Medical College HospitalBeijing 100730China Tufts university School of Medicine Boston MA 02111USA

Although transvaginal mesh(TVM)repair is no longer used in some countries,long-term outcomes after TVM surgery are of great importance ***,reports with follow-up>10 years are ***,this study aimed to report outcomes in a prospective cohort with at least 10 years of *** with stageⅢ–Ⅳsymptomatic prolapse were approached consecutively from 2008 to 2013 at one tertiary *** main outcome measure was symptomatic *** outcomes included anatomic failure,recurrence,patient satisfaction,complications,and *** Kaplan-Meier curve was used to estimate the cumulative failure *** the 121 patients enrolled in the study,103(85.1%)completed a median follow-up of 11 *** estimated probability rates of symptomatic and anatomic failure were 17.6%and 8.8%in 11 years,*** estimated incidence of symptomatic failure increased by 8.2%between 5 and 11 years;however,the corresponding rate for anatomic failure was 3.7%.The most common complication was vaginal mesh exposure,and its estimated probability increased from 19.3%to 28.4%from 5 to 11 years,*** trimming resolved 80.0%of vaginal *** patients did not report decreased overall *** with vaginal mesh exposure requiring>3 office procedures or mesh removal in the operating room(5.8%by 11 years)had lower satisfaction rates(P1)and were defined as having severe mesh *** rates of postoperative pain,reoperation,and Patient Global Impression of Improvement≥2 were 2.5%,3.3%,and 94.2%,*** results of this study implied that TVM treatment gradually increased the symptomatic failure rate but provided durable anatomical support of the vaginal *** mesh exposure was common in women who were largely not sexually active;however,80%of the cases could be managed in the outpatient clinic,which did not affect patient satisfaction.

关键词： complication efficacy long-term follow-up pelvic organ prolapse safety transvaginal mesh

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基于条件异方差分析的水文时序模型及其应用

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系统工程理论与实践 2009年第11期29卷 19-30页

作者：王红瑞高雄常晋源左恒北京师范大学水科学研究院-水沙科学教育部重点实验室北京100875 北京师范大学数学科学学院北京100875

针对条件异方差现象在水文过程的时序研究中常被忽略的情况,建立了水文过程时间序列分析和预测模型.首先,利用Census X12分解水文时序,由其得到的周期项与趋势项分别建立相应的条件异方差模型;其次,对于分解序列后得到的残差项,建立基... 详细信息

针对条件异方差现象在水文过程的时序研究中常被忽略的情况,建立了水文过程时间序列分析和预测模型.首先,利用Census X12分解水文时序,由其得到的周期项与趋势项分别建立相应的条件异方差模型;其次,对于分解序列后得到的残差项,建立基于BX数据生成的灰色Markov预测模型;再次,将三个模型进行耦合,编制了算法流程,由此提出了一种基于条件异方差的水文时序分析与预测模型;最后以河南省淮河流域的鲇鱼山水文站1975-1999年逐月的径流量为例进行了应用验证.研究结果表明:提出的模型从预测效果来看,总的平均偏差只有17.42%,其精度要明显高于常规的水文时序分析中ARCH和ARMA(1,1)等传统方法.

关键词：时间序列分解条件异方差模型灰色BX数据生成法灰色Markov预测模型鲇鱼山水文站

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Molecular basis of the allergenicity and cross-reactivity of a major allergen-Crassostrea gigas arginine kinase

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Food science and Human Wellness 2024年

作者： Yanbo wang PeiAo Zhang Jinru Zhou Jihui gao Jinlyu Sun Di Wu Wentong Xue Dong yang Linglin Fu Food Safety Key Laboratory of Zhejiang Province， School of Food science and Biotechnology， Zhejiang Gongshang university college of Food science & Nutritional Engineering， china agricultural university Allergy Department， State Key Laboratory of Complex Severe and Rare Diseases， Peking Union Medical college Hospital， Chinese Academy of Medical sciences and Peking Union Medical college Institute for Global Food Security， School of Biological sciences， Queen's university of Belfast， 19 Chlorine Gardens

As an important shellfish group， the oyster can induce severe allergic reactions. We aimed to identify and characterize the major allergen in Crassostrea gigas， and elucidate the molecular basis of its allergenicity and cross-reactivity. The native and recombinant C. gigas-AK displayed significant IgG- and IgE-binding activity. The IgE-binding activity of C. gigas-AK could be reduced by thermal treatment and strong acidic and alkaline conditions. Besides， cross-reactivity of AK was demonstrated between shellfish species. Among seven epitope peptides identified here， P2 is responsible for the specificity of C. gigas-AK， while P3 is responsible for cross-reactions between mollusks and crustaceans. Furthermore， Glu98 and His31 in the light chain， Arg101， and Lys57 in the heavy chain are identified as key IgE residues in recognizing epitopes. These findings provide new insights into the prevention and treatment of shellfish allergy and the development of hypoallergenic shellfish products.

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