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Efficacy of scraping therapy on blood pressure and sleep quality in stage Ⅰ and Ⅱ essential hypertension: A systematic review and meta-analysis

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Journal of Integrative Medicine 2024年第1期22卷 12-21页

作者： Zheng-gang zhu Jian-ru Wang Xiao-yan Pan School of Nursing Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina School of Health Sciences Universiti Sains MalaysiaKubang Kerian 16150KelantanMalaysia Department of Cardiovascular Medicine the First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina

Background Scraping therapy is widely used in treating stage I and II essential hypertension in China.However,there has been no systematic evaluation of the efficacy of scraping therapy on blood pressure and sleep quality in stage I and II essential hypertension.Search strategy Seven electronic databases(PubMed,Scopus,Cochrane Library,Web of Science,EBSCO,China National Knowledge Infrastructure and Wanfang Data electronic databases)were searched from inception to December 2022.Based on the principle of combining subject words with text words,the search strategy was constructed around search terms for“scraping therapy,”“scraping,”“Guasha,”“Gua sha,”“hypertension,”and“high blood pressure”during the database searches.Inclusion criteria Randomized controlled trials(RCTs)were included if they recruited patients with stage I and II essential hypertension and included a scraping therapy intervention.The intervention group received antihypertensive drugs and scraping therapy,while the control group only took antihypertensive drugs.Data extraction and analysis Review Manager 5.4.0 and STATA 15.1 were used to enter all the relevant outcome variables to conduct the meta-analysis.The quality of the selected RCTs was assessed using the PEDro scale.The sensitivity analysis was carried out by iteratively excluding individual studies and repeating the analysis to determine the stability of the findings and identify any studies with greater influence on the outcome.Subgroup analysis was performed to find the source of heterogeneity.Funnel plots were used to evaluate the publication bias of included studies.Results Nine RCTs including 765 participants were selected.Meta-analysis showed that scraping therapy combined with medication had an advantage over the use of medication alone in lowering systolic blood pressure(mean difference[MD]=?5.09,95%confidence interval[CI]=?6.50 to?3.67,P<0.001)and diastolic blood pressure(MD=?2.66,95%CI=?3.17 to?2.14,P<0.001).Subgroup analysis showed that scraping therapy improved sleep quality in mid

关键词： Scraping therapy Essential hypertension Efficacy Blood pressure Sleep quality Systematic review Meta-analysis

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Digital Twin for Integration of Design-Manufacturing-Maintenance:An Overview

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Chinese Journal of Mechanical Engineering 2022年第4期35卷 1-20页

作者： Yang Fu gang zhu Mingliang zhu Fuzhen Xuan Key Laboratory of Pressure Systems and Safety Ministry of EducationSchool of Mechanical and Power EngineeringEast China University of Science and TechnologyShanghai 200237China

Traditional design,manufacturing and maintenance are run and managed independently under their own rules and regulations in an increasingly time-and-cost inefective manner.A unifed platform for efcient and intelligent designmanufacturing-maintenance of mechanical equipment and systems is highly needed in this rapidly digitized world.In this work,the defnition of digital twin and its research progress and associated challenges in the design,manufacturing and maintenance of engineering components and equipment were thoroughly reviewed.It is indicated that digital twin concept and associated technology provide a feasible solution for the integration of design-manufacturingmaintenance as it has behaved in the entire lifecycle of products.For this aim,a framework for information-physical combination,in which a more accurate design,a defect-free manufacturing,a more intelligent maintenance,and a more advanced sensing technology,is prospected.

关键词： Digital twin Design-manufacturing-maintenance integration Artifcial intelligence Deep learning Information fusion Cyber-physical systems

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Synthesis, performance and structure characterization of glyoxal-monomethylolurea-melamine (G-MMU-M) co-condensed resin

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中国化学工程学报:英文版 2023年第7期59卷 92-104页

作者： Haixiang Liu Jun Zhang Chunlei Dong gang zhu Guanben Du Shuduan Deng Yunnan Key Laboratory of Wood Adhesives and Glue Products Southwest Forestry UniversityKunming 650224China

In order to reduce the formaldehyde emission of formaldehyde-based wood adhesive from the source,it is aimed to develop a novel co-condensed resin of glyoxal-monomethylolurea-melamine(G-MMU-M).A series of G-MMU-M resins with various formulations of raw materials were successfully prepared.The basic properties and bonding performance of the G-MMU-M resins were determined.Furthermore,the structures of resins were characterized by FTIR,^(13)C NMR,XPS,and ESI-MS.The results show that the prepared G-MMU-M resin remains stable for 30 d,meanwhile,the dry and wet bonding strength of the plywoods bonded with the resins,solid content and viscosity are influenced greatly by the addition amount of melamine and MMU/G molar ratio.The G-MMU-M resins with MMU/G molar ratio of 0.9:1.0 and 8% melamine exhibit the highest dry and bonding strength of 1.98 MPa and 1.27 MPa,increased by 34% and 63%,respectively,in comparison with glyoxal-monomethylolurea(G-MMU)resin.In the G-MMU-M resins,there were four main oligomers including M—CH(—^(+)CH-MMU)-O-MMU,M-CH(—CH_(2)OH)-MMU-O-MMU,M—CH(—OH)—^(+)CH-MMU-O-MMU,and M—CH(—^(+)CH-MMU)-MMU-p-G.

关键词： Wood adhesive Glyoxal-monomethylolurea-melamine Synthesis Chemical reaction Measurement Structure

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亲亲为大:现象学的儒学转向与儒学现象学

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哲学动态 2024年第1期 69-80,F0003页

作者：朱刚中山大学哲学系

现象学运动在其发展历程中曾发生多次转向。现象学的转向最终是由向“回到实事本身”这一精神所推动的:正是因为不同的现象学家们对现象学之实事本身究竞为何有不同的理解,现象学才不断发生转向。在现象学的历次转向中,潜藏着一条以时... 详细信息

现象学运动在其发展历程中曾发生多次转向。现象学的转向最终是由向“回到实事本身”这一精神所推动的:正是因为不同的现象学家们对现象学之实事本身究竞为何有不同的理解,现象学才不断发生转向。在现象学的历次转向中,潜藏着一条以时间性或原初时间为实事本身的线索:从胡塞尔的意识时间到海德格尔的存在或生存时间,再到列维纳斯的伦理时间,正是现象学从意识现象学转向存在论现象学再转向伦理现象学的实质。自现象学与中国哲学尤其是儒学相遇后,现象学又发生了儒学转向。儒学转向之实质正在于它以“亲亲”为原初时间形态,亦即实事本身。现象学的儒学转向以及作为其思想成果的儒学现象学,要在这一以时间性为实事本身的现象学谱系上才能显示出其对于整个现象学运动的意义。

关键词：儒学现象学实事本身亲亲时间意义源头

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创立口头传统研究中国学派的新范式:以交流诗学为例

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民俗研究 2024年第3期 55-69,158页

作者：朱刚中国社会科学院大学北京100732 中国社会科学院民族文学研究所北京100732

作为一个植根于中国活态口头传统的理论模型,交流诗学的主旨在于更新人类口头艺术的研究方法,其一方面延续了20世纪人文及社会科学领域普遍发生的语言转向对于当代民俗学研究方法的视域拓展——以演述为中心的范式转换以及聚焦小群体内... 详细信息

作为一个植根于中国活态口头传统的理论模型,交流诗学的主旨在于更新人类口头艺术的研究方法,其一方面延续了20世纪人文及社会科学领域普遍发生的语言转向对于当代民俗学研究方法的视域拓展——以演述为中心的范式转换以及聚焦小群体内部艺术性交流之民俗概念的当代重构;另一方面也从语言学特别是言语研究的理论发展中获得理论动力,将交流的维度引入口头诗学并进一步拓展了既有人类口头艺术的综合性研究传统。在此基础上,经由中国西部民族地区活态口头传统的民族志研究和比较研究,作为交流的口头艺术与作为诗学的交流行为这一跨学科的学术领域,在理论和实践的双重维度均得到了有益拓展与补充。

关键词：交流诗学口头艺术民俗学语言学比较研究

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Association of acute glycemic parameters at admission with cardiovascular mortality in the oldest old with acute myocardial infarction

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Journal of Geriatric Cardiology 2024年第3期21卷 349-358页

作者： Hui-Hui LIU Meng ZHANG Yuan-Lin GUO Cheng-gang zhu Na-Qiong WU Ying GAO Rui-Xia XU Jie QIAN Ke-Fei DOU Jian-Jun LI Cardiometabolic Center State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

OBJECTIVES Stress-related glycemic indicators,including admission blood glucose(ABG),stress-hyperglycemia ratio(SHR),and glycemic gap(GG),have been associated with worse outcomes after acute myocardial infarction(AMI).However,data regarding their prognostic value in the oldest old with AMI are unavailable.Therefore,this study aimed to investigate the association of stress-related glycemic indicators with short-and long-term cardiovascular mortality(CVM)in the oldest old(≥80 years)with AMI.METHODS In this prospective study,a total of 933 consecutive old patients with AMI admitted to FuWai hospital(Beijing,China)were enrolled.On admission,ABG,SHR,and GG were assessed and all participants were classified according to their quartiles.Kaplan-Meier,restricted cubic splines(RCS),and multivariate Cox regression analyses were performed to evaluate the association between these glycemic indicators and CVM within 30 days and long-term follow-up.RESULTS During an average of 1954 patient-years of follow-up,a total of 250 cardiovascular deaths were recorded.Kaplan-Meier analyses showed the lowest CVM in quartile 1 of ABG and in quartile 2 of SHR and GG.After adjusting for potential covariates,patients in quartile 4 of ABG,SHR,and GG had a respective 1.67-fold(95%CI:1.03-2.69;P=0.036),1.80-fold(95%CI:1.16-2.79;P=0.009),and 1.78-fold(95%CI:1.14-2.79;P=0.011)higher risk of long-term CVM risk compared to those in the reference groups(quartile 1 of ABG and quartile 2 of SHR and GG).Furthermore,RCS suggested a J-shaped relationship of ABG and a Ushaped association of SHR and GG with long-term CVM.Additionally,we observed similar associations of these acute glycemic parameters with 30-day CVM.CONCLUSIONS Our data first indicated that SHR and GG consistently had a U-shaped association with both 30-day and longterm CVM among the oldest old with AMI,suggesting that they may be useful for risk stratification in this special population.

关键词： admitted infarction shaped

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The effect of fasting plasma glucose on in-hospital mortality after acute myocardial infarction in patients with and without diabetes:findings from a prospective,nationwide,and multicenter registry

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Journal of Geriatric Cardiology 2024年第5期21卷 523-533页

作者： Rui FU Ying-Xuan zhu Kong-Yong CUI Jin-gang YANG Hai-Yan XU Dong YIN Wei-Hua SONG Hong-Jian WANG Cheng-gang zhu Lei FENG Wei WU Kai-HongCHEN Yan-Yan ZHAO Ye LU Ke-Fei DOU Yue-Jin YANG on behalf of the CAMI Registry Investigators Cardiometabolic Medicine Center Fuwai HospitalNational Center for Cardiovascular DiseasesState Key Laboratory of Cardiovascular DiseaseNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Medical Research&Biometrics Center Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Coronary Heart Disease Center Fuwai HospitalNational Center for Cardiovascular DiseasesState Key Laboratory of Cardiovascular DiseaseNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Cardiology Guangzhou Traditional Chinese Medical College First Affiliated HospitalGuangdong ProvinceChina Department of Cardiology Longyan Hospital First HospitalFujian ProvinceChina 不详

OBJECTIVES To evaluate the predictive value of fasting plasma glucose(FPG)for in-hospital mortality in patients with acute myocardial infarction(AMI)with different glucose metabolism status.METHODS We selected 5,308 participants with AMI from the prospective,nationwide,multicenter CAMI registry,of which 2,081 were diabetic and 3,227 were nondiabetic.Patients were divided into high FPG and low FPG groups according to the optim-al cutoff values of FPG to predict in-hospital mortality for diabetic and nondiabetic cohorts,respectively.The primary endpoint was in-hospital mortality.RESULTS Overall,94 diabetic patients(4.5%)and 131 nondiabetic patients(4.1%)died during hospitalization,and the optimal FPG thresholds for predicting in-hospital death of the two cohorts were 13.2 mmol/L and 6.4 mmol/L,respectively.Compared with individuals who had low FPG,those with high FPG were significantly associated with higher in-hospital mortality in diabet-ic cohort(10.1%vs.2.8%;odds ratio[OR]=3.862,95%confidence interval[CI]:2.542-5.869)and nondiabetic cohort(7.4%vs.1.7%;HR=4.542,95%CI:3.041-6.782).After adjusting the potential confounders,this significant association was not changed.Further-more,FPG as a continuous variable was positively associated with in-hospital mortality in single-variable and multivariable models regardless of diabetic status.Adding FPG to the original model showed a significant improvement in C-statistic and net reclassification in diabetic and nondiabetic cohorts.CONCLUSIONS This large-scale registry indicated that there is a strong positive association between FPG and in-hospital mor-tality in AMI patients with and without diabetes.FPG might be useful to stratify patients with AMI.

关键词： patients fasting infarction

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Group-Theoretic Remarks on Goldbach’s Conjecture

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Advances in Pure Mathematics 2022年第11期12卷 624-637页

作者： Liguo He gang zhu Department of Mathematics Shenyang University of Technology Shenyang China College of Teacher Education Harbin University Harbin China

The famous strongly binary Goldbach’s conjecture asserts that every even number 2n ≥ 8 can always be expressible as a sum of two distinct odd prime numbers. We use a new approach to dealing with this conjecture. Specifically, we apply the element order prime graphs of alternating groups of degrees 2n and 2n −1 to characterize this conjecture, and present its six group-theoretic versions;and further prove that this conjecture is true for p +1 and p −1 whenever p ≥ 11 is a prime number.

关键词： Alternating Group Element Order Prime Graph Goldbach’s Conjecture Centralizer

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Death after discharge:prognostic model of 1-year mortality in traumatic brain injury patients undergoing decompressive craniectomy

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Chinese Neurosurgical Journal 2022年第1期8卷 36-44页

作者： Wenxing Cui Shunnan Ge Yingwu Shi Xun Wu Jianing Luo Haixiao Lui gang zhu Hao Guo Dayun Feng Yan Qu Department of Neurosurgery Tangdu HospitalNo.569 Xin Si RoadXi’an 710038Shaanxi ProvinceChina

Background:Despite advances in decompressive craniectomy(DC)for the treatment of traumatic brain injury(TBI),these patients are at risk of having a poor long-term prognosis.The aim of this study was to predict 1-year mortality in TBI patients undergoing DC using logistic regression and random tree models.Methods:This was a retrospective analysis of TBI patients undergoing DC from January 1,2015,to April 25,2019.Patient demographic characteristics,biochemical tests,and intraoperative factors were collected.One-year mortality prognostic models were developed using multivariate logistic regression and random tree algorithms.The overall accuracy,sensitivity,specificity,and area under the receiver operating characteristic curves(AUCs)were used to evaluate model performance.Results:Of the 230 patients,70(30.4%)died within 1 year.Older age(OR,1.066;95%CI,1.045-1.087;P<0.001),higher Glasgow Coma Score(GCS)(OR,0.737;95%CI,0.660-0.824;P<0.001),higherD-dimer(OR,1.005;95%CI,1.001-1.009;P=0.015),coagulopathy(OR,2.965;95%CI,1.808-4.864;P<0.001),hypotension(OR,3.862;95%CI,2.176-6.855;P<0.001),and completely effaced basal cisterns(OR,3.766;95%CI,2.255-6.290;P<0.001)were independent predictors of 1-year mortality.Random forest demonstrated better performance for 1-year mortality prediction,which achieved an overall accuracy of 0.810,sensitivity of 0.833,specificity of 0.800,and AUC of 0.830 on the testing data compared to the logistic regression model.Conclusions:The random forest model showed relatively good predictive performance for 1-year mortality in TBI patients undergoing DC.Further external tests are required to verify our prognostic model.

关键词： Decompressive craniectomy Traumatic brain injury One-year mortality Prognostic model Random forest

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Integration of multiscale entropy and BASED scale of electroencephalography after adrenocorticotropic hormone therapy predict relapse of infantile spasms

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World Journal of Pediatrics 2022年第11期18卷 761-770页

作者： Lin Wan Chu-Ting Zhang gang zhu Jian Chen Xiu-Yu Shi Jing Wang Li-Ping Zou Bo Zhang Wen-Bin Shi Chien-Hung Yeh Guang Yang Senior Department of Pediatrics Chinese PLA General HospitalBeijing100000China Department of Pediatrics the First Medical CentreChinese PLA General HospitalBeijingChina Medical School of Chinese People’s Liberation Army BeijingChina School of Information and Electronics Beijing Institute of TechnologyBeijing100081China The Second School of Clinical Medicine Southern Medical UniversityGuangzhouChina Department of Neurology and ICCTR Biostatistics and Research Design Center Boston Children’s HospitalHarvard Medical SchoolBostonMAUSA

Background Even though adrenocorticotropic hormone(ACTH)demonstrated powerful efficacy in the initially successful treatment of infantile spasms(IS),nearly half of patients have experienced a relapse.We sought to investigate whether features of electroencephalogram(EEG)predict relapse in those IS patients without structural brain abnormalities.Methods We retrospectively reviewed data from children with IS who achieved initial response after ACTH treatment,along with EEG recorded within the last two days of treatment.The recurrence of epileptic spasms following treatment was tracked for 12 months.Subjects were categorized as either non-relapse or relapse groups.General clinical and EEG recordings were collected,burden of amplitudes and epileptiform discharges(BASED)score and multiscale entropy(MSE)were carefully explored for cross-group comparisons.Results Forty-one patients were enrolled in the study,of which 26(63.4%)experienced a relapse.The BASED score was significantly higher in the relapse group.MSE in the non-relapse group was significantly lower than the relapse group in theγband but higher in the lower frequency range(δ,θ,α).Sensitivity and specificity were 85.71%and 92.31%,respectively,when combining MSE in theδ/γfrequency of the occipital region,plus BASED score were used to distinguish relapse from non-relapse groups.Conclusions BASED score and MSE of EEG after ACTH treatment could be used to predict relapse for IS patients without brain structural abnormalities.Patients with BASED score≥3,MSE increased in higher frequency,and decreased in lower frequency had a high risk of relapse.

关键词： Burden of amplitudes and epileptiform discharges score Infantile spasms Multiscale entropy Prediction Relapse

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