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刺激响应型DNA水凝胶的设计合成及其在食品安全领域的研究进展

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食品与发酵工业 2024年第11期50卷 360-366页

作者：张鸿鹏谢刚李可敬罗菲窦金鑫朱道兴郭玉垚韩逸陶上海理工大学健康科学与工程学院上海200082 国家粮食和物资储备局科学研究院北京100037 武汉轻工大学食品科学与工程学院湖北武汉430043

具有三维网络结构的DNA水凝胶,因其既具备DNA的生物学特性又兼具水凝胶的骨架功能而备受关注,又由于其具有良好的稳定性和特异性识别能力,可以对多种信号响应,并在凝胶和溶胶之间转换,在生物传感方面得到了广泛的应用。该文围绕DNA水凝... 详细信息

具有三维网络结构的DNA水凝胶,因其既具备DNA的生物学特性又兼具水凝胶的骨架功能而备受关注,又由于其具有良好的稳定性和特异性识别能力,可以对多种信号响应,并在凝胶和溶胶之间转换,在生物传感方面得到了广泛的应用。该文围绕DNA水凝胶的合成、刺激信号类型以及在食品安全领域的应用进行综述。根据合成方法的不同分为物理和化学合成方法,按照刺激信号的类型又可以分为温度响应型、pH响应型、光子响应型、生物分子响应型和多重响应型刺激信号的DNA水凝胶,总结了DNA水凝胶在食品安全领域应用于真菌毒素、重金属离子、食源性致病菌、抗生素残留、非法添加剂检测的研究进展,并对其发展前景进行了阐述。

关键词： DNA水凝胶刺激响应生物传感特异性识别食品安全

Unfalsified control research and its application in inverted pendulum system 25th

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Unfalsified control research and its application in inverted...

Analysis of a class of globally divergence-free HDG methods for stationary Navier-Stokes equations

第25届中国控制与决策会议

作者： Lei Cui Yu Xiang Lv gang xie College of Physics and Optoelectronics Taiyuan University of Technology College of Information Engineering Taiyuan University of Technology

ISBN: (纸本)9781467355322

The traditional control theory is based on the assumption model. which leads to the subjectivity weaknesses in control process. In this paper, we introduced a model-free and data-driven control method - unfalsified control method and described its basic theory in details. This algorithm is applied to the straight line inverted pendulum system. It has simple controller and does not depend on the system model, so it’s suitable for real-time online application. The simulation results verified the validity and efficiency of this theoretical approach.

关键词： Inverted pendulum model-free unfalsified control

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Science China Mathematics 2024年第5期67卷 1133-1158页

作者： gang Chen Xiaoping xie School of Mathematics Sichuan University Chengdu 610064China

In this paper,we analyze a class of globally divergence-free(and therefore pressure-robust)hybridizable discontinuous Galerkin(HDG)finite element methods for stationary Navier-Stokes *** methods use the P_(k)/P_(k-1)(k≥1)discontinuous finite element combination for the velocity and pressure approximations in the interior of elements,piecewise Pm(m=k,k-1)for the velocity gradient approximation in the interior of elements,and piecewise P_(k)/P_(k) for the trace approximations of the velocity and pressure on the inter-element *** show that the uniqueness condition for the discrete solution is guaranteed by that for the continuous solution together with a sufficiently small mesh *** on the derived discrete HDG Sobolev embedding properties,optimal error estimates are *** experiments are performed to verify the theoretical analysis.

关键词： Navier-Stokes equations HDG methods divergence-free uniqueness condition error estimates

Kinetics of austenite grain growth in medium-carbon niobium-bearing steel

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第3期12卷 171-176页

作者： Ying-li ZHAO Jie SHI Wen-quan CAO Mao-qiu WANG gang xie School of Material and Metallurgy Engineering Kunming University of Science and Technology Kunming 650093 China Institute for Structural Materials Central Iron and Steel Research Institute Beijing 100081 China

In order to locate a reasonable heating system,the austenite grain growth behavior of Nb microalloyed medium carbon steel has been experimentally studied at various austenitizing temperatures and for different holding *** is indicated that austenite grain growth increases with increasing austenitizing temperatures and holding *** when the austenitizing temperature was above 1100 ℃,austenite grains grew rapidly,and an abnormal austenite grain growth was *** the austenitizing temperature was lower than 1100 ℃,austenite grain size and growth rate were *** activation energy of grain growth in the tested steel is 397 679.5 J/*** ensure an absence of coarse grains in microstructures,the heating technology of the tested steel should be controlled for 1 h at 1100 ℃.The relationships of austenite average grain size with soaking temperature and time of tested steel were obtained by mathematical calculation,and austenite average grain size was found to be in agreement with the measured size for different holding times.

关键词： Microalloyed steel Grain growth Modeling

Effect of direct quenching on microstructure and mechanical properties of medium-carbon Nb-bearing steel

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第10期11卷 776-781页

作者： Ying-li ZHAO Jie SHI Wen-quan CAO Mao-qiu WANG gang xie School of Material and Metallurgy Engineering Kunming U~iversity of Scienee and Technology Kunming 650093 China Institute for Structural Materials Central Iron and Steel Research Institute Beijing 100081 China

The influence of direct quenching (DQ) on microstructure and mechanical properties of 0.19C-1.7Si-1.0 Mn-0.05Nb steel was studied. The microstructure and mechanical properties of reheat quenched and tempered (RQ&T) steel plate were compared with those of direct quenched and tempered (DQ&T) steel plates which were hot rolled at different finish rolling tem-peratures (1173 K and 1123 K), i.e., recrystallization-controlled-rolled direct-quenched (RCR&DQ) and controlled-rolled direct-quenched (CR&DQ), respectively. The strengths generally increased in the following order: RQ&T

关键词： Direct quenching (DQ) Block Mechanical properties Electron backscattering diffraction (EBSD) Nb steel

Fairness based resource allocation for uplink OFDMA systems

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The Journal of China Universities of Posts and Telecommunications 2008年第2期15卷 50-55页

作者： ZHAO Yi ZENG Ling-kang xie gang LIU Yuan-an XIONG Fang Key Laboratory of Universal Wireless communications Beijing Universityof Posts and Telecommunications Beijing 100876 China

This article investigates two fairness criteria with regard to adaptive resource allocation for uplink orthogonal frequency division multiple access （OFDMA） systems. Nash bargaining solution （NBS） fairness and proportional fairness （PF） are two suitable candidates for fairness consideration, and both can provide attractive trade-offs between total throughput and each user＇s capacity. Utilizing Karush-Kuhn- Tucker （KKT） condition and iterative method, two effective algorithms are designed, to achieve NBS fairness and proportional fairness, respectively. Simulation results show that the proposed resource allocation algorithms achieve good tradeoff between the overall rate and fairness, with little performance loss from the total capacity.

关键词： OFDMA resource allocation fairness

Application of Modified Quasi-Regular Solution Model to Binary Metallurgical Molten Slag Systems

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Journal of Iron and Steel Research International 2010年第10期17卷 13-17,22页

作者： HOU Yan-qing xie gang TAO Dong-ping YU Xiao-hua Faculty of Metallurgical and Energy Engineering Kunming University of Science andTechnology Kunming 650093 Yunnan China

Modified quasi-regular solution model has been available based on the sub-regular solution model and quasiregular solution model in this article. The three parameters of this model are set by the computer-aided analysis based on the experimental data of activity at two different temperatures. Seven binary molten slag systems in the whole concentration are calculated by application of the model and the average relative error is within 10%. Ten binary molten slag systems presenting saturation concentration are also calculated, but the average relative error is bigger, especially for the systems containing acidic oxide and neutral oxide. The results show that the calculated results are superior to those calculated by application of regular solution model, sub-regular solution model and quasi-regular solution model.

关键词： activity binary molten slag modified model sub-regular solution

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四仙颗粒治疗化疗后血小板减少的疗效观察

四川中医 2024年第7期42卷 153-155页

作者：汤利萍向生霞谢刚潘燕四川省中西医结合医院肿瘤科四川成都610041 四川省第二中医医院四川成都610031

目的:抗肿瘤的化疗药物大多会引起患者骨髓造血功能障碍,往往导致治疗不能按时、按量进行,影响化疗效果。血小板下降是骨髓功能被抑制的表现之一,目前虽然皮下注射“白介素-11”、“TPO”对提升血小板疗效肯定,但因价格昂贵等原因,在临... 详细信息

目的:抗肿瘤的化疗药物大多会引起患者骨髓造血功能障碍,往往导致治疗不能按时、按量进行,影响化疗效果。血小板下降是骨髓功能被抑制的表现之一,目前虽然皮下注射“白介素-11”、“TPO”对提升血小板疗效肯定,但因价格昂贵等原因,在临床上受到一定的限制。而采用口服的、价格较为低廉的药物来有效治疗化疗后血小板减少的报道甚少。本研究探讨笔者自拟中药“四仙颗粒”对化疗后血小板减少的治疗效果。方法:2015年2月~2016年12月共观察65例化疗后血小板减少患者。其中治疗组33例,除常规对症治疗外,还每天分3次服用“四仙颗粒”1剂,连服2周。对照组32例,仅行常规对症治疗,观察2周。结果:治疗组显效率21.2%,有效率51.5%,总有效率73.7%;对照组显效率12.5%,有效率37.5%,总有效率25.0%,两组比较,有显著性差异(P<0.01)。结论:“四仙颗粒”能有效提升化疗后下降的血小板水平。

关键词：肿瘤化学疗法血小板减少中药

Exploiting the Community Structure of Fraudulent Keywords for Fraud Detection in Web Search

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Journal of Computer Science & Technology 2021年第5期36卷 1167-1183页

作者： Dong-Hui Yang Zhen-Yu Li Xiao-Hui Wang Kavé Salamatian Gao-gang xie Network Technology Research Center Institute of Computing TechnologyChinese Academy of Sciences Beijing 100190China University of Chinese Academy of Sciences Beijing 100049China Global Energy Interconnection Research Institute Co. Ltd.Beijing 102209China LISTIC Laboratory of Computer Science SystemsInformation and Knowledge ProcessingUniversitéSavoie Mont BlancChambéry 73011France Computer Network Information Center Chinese Academy of SciencesBeijing 100190China

Internet users heavily rely on web search engines for their intended *** major revenue of search engines is advertisements(or ads).However,the search advertising suffers from *** generate fake traffic which does not reach the intended audience,and increases the cost of the ***,it is critical to detect fraud in web *** studies solve this problem through fraudster detection(especially bots)by leveraging fraudsters'unique ***,they may fail to detect new means of fraud,such as crowdsourcing fraud,since crowd workers behave in part like normal *** this end,this paper proposes an approach to detecting fraud in web search from the perspective of fraudulent *** begin by using a unique dataset of 150 million web search logs to examine the discriminating features of fraudulent ***,we model the temporal correlation of fraudulent keywords as a graph,which reveals a very well-connected community ***,we design DFW(detection of fraudulent keywords)that mines the temporal correlations between candidate fraudulent keywords and a given list of *** particular,DFW leverages several refinements to filter out non-fraudulent keywords that co-occur with seeds *** evaluation using the search logs shows that DFW achieves high fraud detection precision(99%)and accuracy(93%).A further analysis reveals several typical temporal evolution patterns of fraudulent keywords and the co-existence of both bots and crowd workers as fraudsters for web search fraud.

关键词： community structure fraud analysis fraudulent keyword detection web search