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Selenoprotein-p and insulin resistance in children and adolescents with obesity

World Journal of Clinical Pediatrics 2024年第3期13卷 40-52页

作者： Amany elbarky Kholoud gamal Ismail Yousef Fouad Yousef Rasha mohamed gamal elshafiey Radwa mahmoud elsharaby Asmaa el-Kaffas mohammed Al-Beltagi Gastroenterology and Clinical Nutrition Unit Pediatric DepartmentFaculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Clinical Pathology Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Paediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain

BACKGROUND Insulin resistance and obesity present significant challenges in pediatric *** P1(SEPP1)serves as a biomarker for assessing selenium levels in the *** its association with metabolic syndrome is established in adults,its relevance in children remains *** To ascertain SEPP1 blood levels in children and adolescents diagnosed with obesity and to assess its correlation with insulin resistance and adiposity *** 170 children participated in this study,including 85 diagnosed with obesity and an equal number of healthy counterparts matched for age and *** participant underwent a comprehensive medical evaluation,encompassing a detailed medical history,clinical examination,and anthropometric measurements like waist circumference and waist-to-height ***,routine blood tests were conducted,including serum SEPP1,visceral adiposity index(VAI),and Homeostatic model Assessment of Insulin Resistance(HOmA-IR)*** Our findings revealed significantly lower serum SEPP1 levels in children with obesity compared to their healthy ***,notable negative correlations were observed between serum SEPP1 levels and body mass index,VAI,and *** The study suggests that SEPP1 could serve as a valuable predictor for insulin resistance among children and adolescents diagnosed with *** highlights the potential utility of SEPP1 in pediatric metabolic health assessment and warrants further investigation.

关键词： Obesity Childhood obesity Selenium status Selenoprotien P1 Insulin resistance

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Asymptomatic bile duct stones:The devil is in the details

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World Journal of Gastrointestinal Endoscopy 2024年第5期16卷 227-231页

作者： mohammed Omar Khalifa elsayed mohamed gamal Talkhan Department of Gastroenterology South Tees Hospitals NHS Foundation TrustMiddlesbrough TS43BWUnited Kingdom

Common bile duct(CBD)stones are a common biliary tract *** asymp-tomatic CBD stones,stone removal by endoscopic retrograde cholangiopancreato-graphy(ERCP)is recommended in available *** asymptomatic CBD stones is a benign disease with no noticeable symptoms,the risk vs benefit strategy should be thoroughly considered before performing ERCP in these *** care review,technical aspects of the procedure,and patient preferences should also be considered.

关键词： Asymptomatic Common bile duct stones Endoscopic retrograde cholangiopancreatography Outcome Guidelines

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Does salinity change determine zooplankton variability in the saline Qarun Lake(Egypt)?

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Chinese Journal of Oceanology and Limnology 2015年第6期33卷 1368-1377页

作者： gamal m.el-SHABRAWY elena V.ANUFRIIEVA mousa O.GERmOUSH mohamed E.GOHER Nickolai V.SHADRIN National Institute of Oceanography and Fisheries Fish Research Station mLR Key Laboratory of Saline Lake Resources and Environments Institute of Mineral Resources Institute of Biology of the Southern Seas Biology Department College of ScienceAl Jouf University

Zooplankton and 14 abiotic variables were studied during August 2011 at 10 stations in Lake Qarun, Egypt. Stations with the lowest salinity and highest nutrient concentrations and turbidity were close to the discharge of waters from the el-Bats and E1-Wadi drainage systems. A total of 15 holozooplankton species were identified. The salinity in Lake Qarun increased and fluctuated since 1901：12 g/L in 1901; 8.5 g/L in 1905; 12.0 g/L in 1922; 30.0 g/L in 1985; 38.7 g/L in 1994; 35.3 g/L in 2006, and 33.4 g/L in 2011. The mean concentration of nutrients （nitrate, nitrite and orthophosphate） gradually increased from 35, 0.16 and 0.38 μg/L, respectively, in 1953-1955 to 113, 16.4, and 30.26 μg/L in 2011. From 1999-2003 some decrease of species diversity occurred. Average total zooplankton density was 30 000 ind./m^3 in 1974-1977; 356 125 ind./m^3 in 1989; 534 000 ind./m^3 in 1994-1995; from 965 000 to 1 452 000 ind./m^3 in 2006, and 595 000 ind./m^3 in 2011. A range of long-term summer salinity variability during the last decades was very similar to a range of salinity spatial variability in summer 2011. There is no significant correlation between zooplankton abundance and salinity in spatial and long-term changes. We conclude that salinity fluctuations since at least 1955 did not directly drive the changes of composition and abundance of zooplankton in the lake. A marine community had formed in the lake, and it continues to change. One of the main drivers of this change is a regular introduction and a pressure of alien species on the existent community. Eutrophication also plays an important role. The introduction ofmnemiopsis leidyi, first reported in 2014, may lead to a start of a new stage of the biotic changes in Lake Qarun, when eutrophication and the population dynamics of this ctenophore will be main drivers of the ecosystem change.

关键词： saline lake Copepoda Rotifera mnemiopsis leidyi alien species

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The Effect of Atrial Septal Defect Closure on Cardiac Volumetric Changes in Adults, Transcatheter Versus Surgical Closure, a Pilot Cardiac magnetic Resonance Study

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Congenital Heart Disease 2023年第6期18卷 679-691页

作者： Amr mansour Noha m.gamal Alaa m.Nady Amr Ibraheem Dalia m.Salah Khaled m.el-maghraby Cardiology Department Congenital and Structural Heart Disease UnitAin Shams University HospitalsFaculty of MedicineAin Shams UniversityCairoEgypt Cardiology Department Faculty of MedicineAssuit UniversityAssuitEgypt Cardiothoracic Surgery Department Faculty of MedicineAssuit UniversityAssuitEgypt Anesthesia Department Faculty of MedicineAssuit UniversityAssuitEgypt

Background:Closure of an atrial septal defect(ASD)reduces right-side heart volumes by abolishing shunting with simultaneous improvement of the left ventricle(LV)ﬁlling and functions due to ventricular interdependence,thereby improving ***,studies conducted on atrial volume changes after ASD closure are *** magnetic resonance(CmR)is considered as the gold standard method for measuring cardiac volume and ***:We aimed to study the effect of transcatheter and surgical closure of secundum ASD on cardiac volumes and systolic functions as well as the fate of tricuspid regurgitation(TR),using CmR ***:We prospectively enrolled 30 adult patients with isolated secundum ASD who were referred to ASD *** evaluation of cardiac chambers indexed volumes,systolic function,myocardial mass index,and tricuspid regurgitant fraction were done at before and 6 months after ***:RV volumes decreased in both groups when compared to baseline(p-value 0.001),the device group had more reduction in volumes and more improvement in RV function after closure(p-value 0.001)when compared to the surgical *** changes in the RV mass index were insigniﬁcant between both groups(p-value 0.31).Functional TR improved to the same extent in both *** ventricular end diastolic volume index(LVEDVI)and LV mass index increased sig-niﬁcantly in both groups when compared to baseline in both groups but with no difference between groups p-value 0.01),left ventricular end systolic volume index(LVESVI)changes were insigniﬁ*** systolic function improved in patients who underwent device closure only(63.53±3.85 vs.67.13±4.34,p-value 0.01).There was a signiﬁcant reduction in right atrial(RA)volumes and an insigniﬁcant decrease in left atrial(LA)volumes,with no difference between ***:Transcatheter and surgical secundum ASD closure resulted in volumetric changes in some cardiac chambers with better improvement in bi-ventricular

关键词： Atrial septal defect closure cardiac volumetric changes functional tricuspid regurgitation cardiac CmR

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microstructure and mechanical properties of hot extruded 6016 aluminum alloy/graphite composites

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Journal of materials Science & Technology 2018年第9期34卷 1580-1591页

作者： mohamed m.el-Sayed Seleman mohamed m.Z.Ahmed Sabbah Ataya Department of metallurgical and materials Engineering Faculty of Petroleum and Mining Engineering Suez University 43518 Suez Egypt Suez and Sinai metallurgical and materials Research Center of Scientific Excellence (SSmmR-CSE) 43518 Suez Egypt The British University in Egypt Mechanical Engineering Deportment El-Sherouk City 11837 Cairo Egypt Department of mechanical Engineering College of Engineering AI Imam Mohammad Ibn Saud Islamic University Riyadh 11432 saudi Arabia

The incorporation of graphite particles into AA6016 aluminum alloy matrix to fabricate metal/ceramic composites is still a great challenge and various parameters should be considered. In this study, dense AA6016 aluminum alloy/（0-20 wt%） graphite composites have successfully been fabricated by powder metallurgy process. At first, the mixed aluminum and graphite powders were cold compacted at 200 mPa and then sintered at 500 ℃ for 1 h followed by hot extrusion at 450 ℃. The influence of ceramic phases（free graphite and in-situ formed carbides） on microstructure, physical and mechanical properties of the produced composites were finally investigated. The results show that the fabricated composites have a relative density of over 98%. SEm observations indicate that the graphite has a good dispersion in the alloy matrix even at high graphite content. Hardness of all the produced composites was higher than that of aluminum alloy matrix. No cracks were observed at strain less than 23% for all hot extruded *** strength, reduction in height, ultimate tensile stress, fracture stress, yield stress, and fracture strain of all Al/graphite composites were determined by high precision second order equations. Both compressive and ultimate tensile strengths have been correlated to microstructure constituents with focusing on the in-situ formed ceramic phases, silicon carbide（SiC） and aluminum carbide（Al4 C3）. The ductile fracture mode of the produced composites became less dominant with increasing free graphite content and in-situ formed carbides. Wear resistance of Al/graphite composites was increased with increasing graphite content. Aluminum/20 wt% graphite composite exhibited superior wear resistance over that of AA6016 aluminum alloy.

关键词： AA6016/graphite composites Hot extrusion In-situ carbides mechanical properties Wear resistance Fracture behavior

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Effect of Conductive Fillers on the Cyclic Stress-Strain and Nano-Scale Free Volume Properties of Silicone Rubber

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Chinese Journal of Polymer Science 2014年第5期32卷 558-567页

作者： m.H.Abd-el Salam S.el-gamal m.mohsen D.m.Abd el-maqsoud Physics Department Faculty of Education Ain Shams University Physics Department Faculty of Science Ain Shams University

The effect of carbon black （CB） and graphite （G） powders on the macroscopic and nano-scale free volume properties of silicone rubber based on poly（di-methylsiloxane）（PDmS） was studied through thermal and cyclic mechanical measurements, as well as with positron annihilation lifetime spectroscopy （PALS）. The melting temperature of the composites （Tm） and the endothermic enthalpy of melting （ΔHm） were estimated by differential scanning calorimetry （DSC）. Tm and the degree of crystallinity （χc） of PDmS composites were found to decrease with increasing the CB content. This can be explained due to the increase in physical cross-linking which results in a decrease in the crystallite thickness. Besides, χc was found to be dependent on the filler type. Cyclic stress-strain behavior of PDmS loaded with different contents of filler has been studied. mullins ratio （Rm） was found to be dependent on the filler type and content. It was found that, Rm increases with increasing the filler content due to the increase in physical cross-linking which results in a decrease in the size of free volume, as observed through a decrease of the o-Ps lifetime τ3 measured by PALS. moreover, the hysteresis in PDmS-CB composites was more pronounced than in PDmS-G composites. Furthermore, a correlation was established between the free volume Vf and the mechanical properties of PDmS composites containing different fillers. A negative correlation was observed between Vf and Rm.

关键词： Positron annihilation Positronium Free volume Si-rubber Composite Cyclic mechanical properties.

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A computer-based image analysis for tear ferning featuring

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Journal of Innovative Optical Health Sciences 2015年第5期8卷 40-49页

作者： Ali S.Saad gamal A.el-Hiti Ali m.masmali Department of Biomedical Technology College of Applied medical Sciences King Saud University P.O.Box 10219 Riyadh 11433Saudi Arabia Cornea Research Chair(CRC) Department of Optometry College of Applied Medical SciencesKing Saud University Riyadh 11433Saudi Arabia

The present work focuses on the development of a novel computer-based approach for tear ferning(TF)*** original TF images of the recently developedfive-point grading scale have been used to assign a grade for any TF image automatically.A vector characteristic(VC)representing each grade was built using the reference images.A weighted combination between features selected from textures analysis using gray level co-occurrence matrix(GLCm),power spectrum(PS)analysis and linear specificity of the image were used to build the VC of each grade.A total of 14 features from texture analysis were *** at di®erent frequency points and number of line segments in each image were also *** features from GLCm have shown significant di®erences between the recently developed grading scale images which are:angular second moment at 0and 45,contrast,and correlation at 0and 45;thesefive features were all included in the characteristic *** specific power frequencies were used in the VC because of the discrimination *** of line segments was also chosen because of dissimilarities between images.A VC for each grade of TF reference images was constructed and was found to be significantly different from each other'*** is a basic and fundamental step toward an automatic grading for computer-based diagnosis for dry eye.

关键词： Objective grading tear ferning new grading scale texture analysis image processing PS

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Tailored pancreatic reconstruction after pancreaticoduodenectomy: a single-center experience of 892 cases

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Hepatobiliary & Pancreatic Diseases International 2017年第5期16卷 528-536页

作者： Ayman el Nakeeb Ahmad m Sultan Ehab Atef Ali Salem mostaffa Abu Zeid Ahmed Abu el Eneen gamal el Ebidy mohamed Abdel Wahab Gastroenterology Surgical Center Mansoura UniversityMansoura 35516 Egypt

BACKGROUND: Pancreatic reconstruction following pancreaticoduodenectomy(PD) is still debatable even for pancreatic surgeons. Ideally, pancreatic reconstruction after PD should reduce the risk of postoperative pancreatic fistula(POPF) and its severity if developed with preservation of both exocrine and endocrine pancreatic functions. It must be tailored to control the morbidity linked to the type of *** study was to show the best type of pancreatic reconstruction according to the characters of pancreatic stump. mETHODS: We studied all patients who underwent PD in our center from January 1993 to December 2015. Patients were categorized into three groups depending on the presence of risk factors of postoperative complications: low-risk group(absent risk factor), moderate-risk group(presence of one risk factor) and high-risk group(presence of two or more risk factors). RESULTS: A total of 892 patients underwent PD for resection of periampullary tumor. BmI >25 kg/m~2, cirrhotic liver, soft pancreas, pancreatic duct diameter mm, and pancreatic duct location from posterior edge mm are risk variables for development of postoperative complications. POPF developed in 128(14.3%) patients. Delayed gastric emptying occurred in 164(18.4%) patients, biliary leakage developed in 65(7.3%) and pancreatitis presented in 20(2.2%). POPF in low-, moderate-and high-risk groups were 26(8.3%), 65(15.7%) and 37(22.7%) patients, respectively. Postoperative morbidity and mortality were significantly lower with pancreaticogastrostomy(PG) in high-risk group, while pancreaticojejunostomy(PJ) decreases incidence of postoperative steatorrhea in all groups. CONCLUSIONS: Selection of proper pancreatic reconstruction according to the risk factors of patients may reduce POPF and postoperative complications and mortality. PG is superior to PJ as regards short-term outcomes in high-risk group but PJ provides better pancreatic function in all groups and therefore, PJ is superior in l

关键词： periampullary tumor pancreaticogastrostomy pancreaticojejunostomy pancreaticoduodenectomy postoperative pancreatic fistula

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Turbulent flame image classification using Convolutional Neural Networks

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能源与人工智能(英文) 2022年第4期10卷 87-94页

作者： Rathziel Roncancio Aly el gamal Jay P.Gore School of mechanical Engineering Purdue UniversityWest LafayetteIN47907USA School of electrical and Computer Engineering Purdue UniversityWest LafayetteIN 47907USA

Pockets of unburned material in turbulent premixed flames burning CHs,air,and CO_(2) were studied using OH Planar Laser-Induced Fuorescence(PLIF)images to improve current *** flames are ubiquitous in most natural gas air combustors running gas turbines with dry exhaust gas recirculation(EGR)for land-based power *** improvements continue in the charactenization and understanding of turbulent flames with EGR particularly for transient events like ignition and *** and/or islands of unburned material within bumed and unburned turbulent media are some of the features of these *** features reduce the heat release rates and increase the carbon monoxide and hydrocarbons *** present work involves Convolutional Neural Networks(CNN)based dassification of PIF images containing unburned pockets in three turbulent flames with 0%,5%,and 10%CO_(2).The CNN model was constructed using three convolutional layers and two fully connected layers using dropout and weight *** of 94.2%,92.3%and 89.2%were registered for the three flames,*** present approach represents significant computational time savings with respect to conventional image processing methods.

关键词： CNN Flame Neural network Turbulent

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The role and potential of attapulgite in catalytic pyrolysis of refinery waste activated sludge

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Petroleum Science 2022年第1期19卷 354-362页

作者： Qinghong Wang Kanghong Hao Chelsea Benally Yue Kou Zhexuan An mohamed gamal el-Din Chunmao Chen State Key Laboratory of Heavy Oil Processing Beijing Key Laboratory of Oil and Gas Pollution ControlChina University of Petroleum-BeijingBeijing102249China Department of Civil and Environmental Engineering University of AlbertaEdmontonAlbertaT6G 1H9Canada

Pyrolysis is a promising technology for the treatment of refinery waste activated sludge(rWAS).In this study,attapulgite as a natural clay was used to enhance the pyrolysis of *** yields,characteristics of pyrolytic products,pyrolytic kinetics and mechanisms were *** attapulgite improved the conversion of rWAS into non-condensable gases and pyrolytic *** bio-oil quality improved and the biochar yield *** average activation energy of Stage Ⅰ(230-400℃)and Stage Ⅱ(400-500℃)decreased by 36.5%and 49.7%,respectively,compared to rWAS ***_(2)O_(3)and Fe_(2)O_(3)in attapulgite enhanced the dealkylation reaction and cracking of C-C *** content of the gasoline(elative to rWAS *** promoted the deoxygenation,dehydroxylation and dehydrogenation reactions of O-containing compounds,and the content of CO and CO_(2) in non-condensable gases *** of attapulgite(rWAS:attapulgite ratio of 1:1)decreased the O mobility from 14.6%to 12.8%relative to rWAS ***,the content of saturates in bio-oil increased from 38.5 wt%to 47.2 wt%and the lower heating value(LHV)increased from 6.8 kcal/kg to 8.4 kcal/*** heavy metals originally in rWAS were fixed into the pyrolytic residue and the environmental risks are *** study demonstrates the role and potential of attapulgite in catalytic pyrolysis of rWAS with an added advantage of increased cost-effectiveness.

关键词： Catalytic pyrolysis Attapulgite Kinetics Product characteristics

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