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Innovative single-shot 2D pulse front tilt diagnostic

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High Power Laser Science and Engineering 2021年第2期9卷 26-30页

作者： M.Galimberti f.G.Bisesto M.galletti Central Laser facility Science and Technology Facilities CouncilRutherford Appleton LaboratoryDidcotUK INfN Laboratori Nazionali di frascati FrascatiItal

The presence of pulse front tilt(PfT),caused by angular dispersion(AD)in femtosecond laser pulses,could degrade the performance of the laser system and/or impact the experimental *** present a single-shot diagnostic capable of measuring the AD in the x–y plane by adopting an intensity *** can be applied to stretched pulses,making it ideal for diagnosing the AD along the amplification chain of a high-power laser system,and to ultrashort pulses exiting from an optical *** this way,it can help in properly characterizing a laser pulse before it is delivered to the target *** this Letter,we present experimental evidence of AD retrieval for different compression configurations,supported by theoretical analysis.

关键词： femtosecond pulses high-power laser laser diagnostics pulse front tilt

Ultra-broadband near-infrared NOPAs based on the nonlinear crystals Bi BO and YCOB

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High Power Laser Science and Engineering 2020年第3期8卷 6-15页

作者： Mario galletti Hugo Pires Victor Hariton Joana Alves Pedro Oliveira Marco Galimberti Goncalo figueira GoLP/Instituto de Plasmas e fusao Nuclear Instituto Superior TecnicoUniversidade de Lisboa1049-001 LisboaPortugal Central Laser facility Science and Technology Facilities CouncilRutherford Appleton LaboratoryHarwell Science and Innovation CampusDidcotUK INfN-LNf Via Enrico Fermi 5400044 FrascatiItaly

We evaluate and demonstrate ultra-broadband near-infrared noncollinear optical parametric amplification in two nonlinear crystals,bismuth borate(Bi BO)and yttrium calcium oxyborate(YCOB),which are not commonly used for this *** spectral bandwidth is of the microjoule level;the amplified signal is≥200 nm,capable of supporting sub-10 fs *** results,supported by numerical simulations,show that these crystals have a great potential as nonlinear media in both low-energy,few-cycle systems and high peak power amplifiers for terawatt to petawatt systems based on noncollinear optical parametric chirped pulse amplification(NOPCPA)or a hybrid.

关键词： ultrafast laser high power laser nonlinear optics ultra-broadband noncollinear OPA YCOB and Bi BO nonlinear crystal

High efficiency second harmonic generation of nanojoule-level femtosecond pulses in the visible based on BiBO

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High Power Laser Science and Engineering 2019年第1期7卷 82-89页

作者： Mario galletti Hugo Pires Victor Hariton Celso Paiva Joao Swen Künzel Marco Galimberti Goncalo figueira GoLP/Instituto de Plasmas e fusao Nuclear Instituto Superior Técnico Universidade de Lisboa Central Laser facility Science and Technology Facilities Council Rutherford Appleton Laboratory Harwell Science and Innovation Campus

We demonstrate high efficiency second harmonic generation(SHG) of near infrared femtosecond pulses using a BiB3 O6 crystal in a single-pass tight focusing geometry setup. A frequency doubling efficiency of 63% is achieved, which is,to the best of our knowledge, the highest value ever reported in the femtosecond regime for such low energy(nJ-level)pumping pulses. Theoretical analyses of the pumping scheme focusing waist and the SHG efficiency are performed, by numerically solving the three wave mixing coupled equations in the plane-wave scenario and by running simulations with a commercial full 3 D code. Simulations show a good agreement with the experimental data regarding both the efficiency and the pulse spectral profile. The simulated SHG pulse temporal profile presents the characteristic features of the group velocity mismatch broadening in a ‘thick' crystal.

关键词： nonlinear process second harmonic generation pumping scheme parametric amplification/oscillators high power laser

Review on TNSA diagnostics and recent developments at SPARC LAB

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High Power Laser Science and Engineering 2019年第3期7卷 228-239页

作者： fabrizio Bisesto Mario galletti Maria Pia Anania Massimo ferraro Riccardo Pompili Mordechai Botton Elad Schleifer Arie Zigler INfN-LNf Via Enrico Fermi 4000044 FrascatiItaly Central Laser facility Science and Technology Facilities CouncilRutherford Appleton LaboratoryHarwell Science and Innovation CampusDidcot 0X11 OQXUK GoLP Instituto de Plasmas e fusao Nuclear Instituto Superior TecnicoUniversidade de LisboaAv.Rovisco Pais 1049-001 LisbonPortugal Racah Institute of Physics Hebrew University91904 JerusalemIsrael

Interaction between high-intensity lasers with solid targets is the key process in a wide range of novel laser-based particle accelerator schemes,as well as electromagnetic radiation *** to all the processes is the generation of femtosecond pulses of relativistic electrons emitted from the targets as forerunners of the later-time principal products of the interaction *** this paper,some diagnostics employed in laser–solid matter interaction experiments related to electrons,protons,ions,electromagnetic pulses(EMPs)and X-rays are ***,we present our experimental study regarding fast electrons and EMPs utilizing a femtosecond-resolution detector previously adopted only in accelerator facilities.

关键词： high power laser laser-plasma interaction pulsed electric field diagnostic ultra-short high-intensity laser pulses

Classifying Cardiac Anomalies in Right and Left Isomerism:Concordant and Discordant Patterns

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Congenital Heart Disease 2023年第1期18卷 97-111页

作者： Lilia Oreto Giuseppe Mandraffino Paolo Ciliberti Teresa P.Santangelo Placido Romeo Antonio Celona Placido Gitto Lorenzo galletti fiore S.Iorio Alfredo Di Pino Aurelio Secinaro Paolo Guccione Robert H.Anderson Salvatore Agati Mediterranean Pediatric Cardiology Center Bambino GesùChildren’s HospitalVia SirinaTaorminaItaly Internal Medicine Unit Department of Clinical and Experimental MedicineUniversity of MessinaMessinaItaly Department of Pediatric Cardiology and Cardiac Surgery Bambino GesùChildren’s HospitalRomaItaly Advanced Cardiovascular Imaging Unit Department of ImagingBambino GesùChildren’s HospitalRomaItaly Radiology Department S.Vincenzo HospitalTaorminaItaly Biosciences Institute Newcastle UniversityNewcastle upon TyneUK

Aims:Evidence is emerging that,in the setting of isomerism,the atrial and bronchial arrangement are not always concordant,nor are these patterns always harmonious with the arrangement of the abdominal *** aimed to evaluate the concordance between these features in a cohort of patients with cardiac malformations in the setting of known isomerism,seeking to determine whether it was feasible to assess complexity on this basis,in this regard taking note of the potential value of bronchial as opposed to appendage *** and Results:We studied 78 patients known to have isomerism of the bronchuses,43 with right and 35 with left *** anatomy could be determined in 49 cases(63%),all but one of these being concordant with bronchial *** assessing abdominal features,in only 59 cases(76%)was splenic morphology in keeping with the thoracic *** expected,right isomerism was associated with greater complexity of cardiac malformations,with an odds ratio of 6.53,with confidence intervals from 2.2–19.3(pfound in the setting of left ***:Harmony is excellent between bronchial and appendage isomerism,but less so with the arrangement of the abdominal *** isomerism in our cohort,was indicative of a sixfold increase in intracardiac *** discordance was found between the systems,however,the cardiac anomalies were less typical of the anticipated findings for right *** isomerism of the appendages.

关键词： Isomerism asplenia polysplenia congenital heart disease bronchial isomerism atrial appendages

预测20年总死亡与心血管病死亡风险增加的尿酸阈值

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中华高血压杂志 2020年第1期28卷 99-99页

作者： Virdis A Masi S Casiglia E Tikhonoff V Cicero AfG Ungar A Rivasi G Salvetti M Barbagallo CM Bombelli M Dell'Oro R Bruno B Lippa L D'Elia L Verdecchia P Mallamacif Cirillo M Rattazzi M Cirillo P Gesualdo L Mazza A Giannattasio C Maloberti A Volpe M Tocci G GeorgiopoulosG Iaccarino G Nazzaro P Parati G Palatini P galletti f ferri C Desideri G Viazzi f Pontremoli R Muiesan ML Grassi G Borghi C 赵狄(摘译) 刘莉(审校) 不详

目前识别心血管病风险不同分层的血清尿酸水平仍未确定。采用基于人群的大数据,研究人员评估了总死亡和与心血管病死亡(cardiovascular mortality,CVM)风险增加的血清尿酸水平。尿酸与心脏健康(uric acid right for heart health,URRAH... 详细信息

目前识别心血管病风险不同分层的血清尿酸水平仍未确定。采用基于人群的大数据,研究人员评估了总死亡和与心血管病死亡(cardiovascular mortality,CVM)风险增加的血清尿酸水平。尿酸与心脏健康(uric acid right for heart health,URRAH)研究是一项收集意大利几个基于大型人群纵向研究大数据的多中心回顾性观察性研究(随访20年),患者均在意大利高血压协会的高血压诊所就诊。

关键词：心血管病尿酸水平死亡风险

Activation of Defense Response Pathways by OGs and fig22 Elicitors in Arabidopsis Seedlings

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Molecular Plant 2008年第3期1卷 423-445页

作者： Carine Denoux Roberta galletti Nicole Mammarella Suresh Gopalan Danièle Werck Giulia De Lorenzo Simone ferrari frederick M. Ausubel Julia Dewdney Department of Genetics Harvard Medical School and Department of Molecular Biology Massachusetts General Hospital 185 Cambridge St Simches 7700Boston MA 02114 USA Institut de Biologie Moleculaire des Plantes CNRS Universite Louis Pasteur. Strasbourg France Dipartimento di Biologia Vegetale University di Roma 'La Sapienza' Piazzale Aldo Moro 5 00185 Rome. Italy

We carried out transcriptional profiling analysis in 10-d-old Arabidopsis thaliana seedlings treated with oligogalacturonides （OGs）, oligosaccharides derived from the plant cell wall, or the bacterial flagellin peptide fig22, general elicitors of the basal defense response in plants. Although detected by different receptors, both OGs and fig22 trigger a fast and transient response that is both similar and comprehensive, and characterized by activation of early stages of multiple defense signaling pathways, particularly JA-associated processes. However, the response to fig22 is stronger in both the number of genes differentially expressed and the amplitude of change. The magnitude of induction of individual genes is in both cases dose-dependent, but, even at very high concentrations, OGs do not induce a response that is as comprehensive as that seen with fig22. While high doses of either microbe-associated molecular pattern （MAMP） elicit a late response that includes activation of senescence processes, SA-dependent secretory pathway genes and PR1 expres- sion are substantially induced only by fig22. These results suggest a lower threshold for activation of early responses than for sustained or SA-mediated late defenses. Expression patterns of amino-cyclopropane-carboxylate synthase genes also implicate ethylene biosynthesis in regulation of the late innate immune response.

关键词： fig22 唇形科种子活化作用

Ultra-broadband all-OPCPA petawatt facility fully based on LBO

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High Power Laser Science and Engineering 2020年第4期8卷 1-16页

作者： Mario galletti Pedro Oliveira Marco Galimberti Munadi Ahmad Giedre Archipovaite Nicola Booth Emerald Dilworth Andy frackiewicz Trevor Winstone Ian Musgrave Cristina Hernandez-Gomez GoLP/Instituto de Plasmas e fusao Nuclear Instituto Superior TecnicoUniversidade de Lisboa1049-001 LisboaPortugal Central Laser facility Science and Technology Facilities CouncilRutherford Appleton LaboratoryHarwell Science and Innovation CampusDidcotUK INfN-LNf Via Enrico Fermi 5400044 FrascatiItaly School of Engineering and Physical Sciences Heriot-Watt UniversityEdinburghUK

A petawatt facility fully based on noncollinear optical parametric chirped pulse amplification(NOPCPA)technology,Vulcan OPPEL(Vulcan OPCPA PEtawatt Laser),is *** system will be coupled with the existing hybridCPA/OPCPA VULCAN laser system(500 J,500 fs beamline;250 J,ns regime beamline)based on Nd:glass *** pulse duration(20 times shorter)combined with the system design will allow the auxiliary beamline and its secondary sources to be used as probe beams for longer pulses and their interactions with *** newly designed system will be mainly dedicated to electron beam generation,but could also be used to perform a variety of particle acceleration and optical radiation detection experimental *** this communication,we present the entire beamline design discussing the technology choices and the design supported by extensive simulations for each system ***,we present experimental results and details of our commissioned NOPCPA picosecond front end,delivering 1.5 mJ,~180 nm(1/e^(2))of bandwidth compressed to sub-15 fs.

关键词： high-power laser LBO nonlinear crystal nonlinear optics ultra-broadband OPA ultrafast laser

Simultaneous observation of ultrafast electron and proton beams in TNSA

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High Power Laser Science and Engineering 2020年第2期8卷 147-152页

作者： fabrizio Bisesto Mario galletti Maria Pia Anania Gemma Costa Massimo ferrario Riccardo Pompili Arie Zigler fabrizio Consoli Mattia Cipriani Martina Salvadori Claudio Verona INfN-LNf Via Enrico Fermi 5400044 FrascatiItaly Central Laser facility Science and Technology Facilities CouncilRutherford Appleton LaboratoryHarwell Science and Innovation CampusDidcot OX110QXEngland GoLP Instituto de Plasmas e fusao Nuclear Instituto Superior TecnicoUniversidade de LisboaAv.Rovisco Pais1049-001 LisbonPortugal Racah Institute of Physics Hebrew University91904 JerusalemIsrael ENEA fusion and Technologies for Nuclear Safety and Security Department C.R.FrascatiVia E.Fermi 4500044 FrascatiItaly Universita’di Roma La Sapienza Piazzale Aldo Moro 500185 RomaItaly INRS-EMT VarennesQuebecCanada University of Rome“Tor Vergata” Industrial Engineering DepartmentVia Cracovia 5000133 RomaItaly

The interaction of ultra-intense high-power lasers with solid-state targets has been largely studied for the past 20 years as a future compact proton and ion ***,the huge potential established on the target surface by the escaping electrons provides accelerating gradients of TV/*** process,called target normal sheath acceleration,involves a large number of phenomena and is very difficult to study because of the picosecond scale *** the SPARC LAB Test facility,the high-power laser fLAME is employed in experiments with solid targets,aiming to study possible correlations between ballistic fast electrons and accelerated *** detail,we have installed in the interaction chamber two different diagnostics,each one devoted to characterizing one *** first relies on electro-optic sampling,and it has been adopted to completely characterize the ultrafast electron *** the other hand,a time-of-flight detector,based on chemical-vapour-deposited diamond,has allowed us to retrieve the proton energy *** this work,we report preliminary studies about simultaneous temporal resolved measurements of both the first forerunner escaping electrons and the accelerated protons for different laser parameters.

关键词： electro-optic sampling diagnostics high-power laser laser-plasma interaction time-of-flight diagnostics target normal sheath acceleration ultrashort high-intensity laser pulses