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Natural Disaster Reduction in China 1980年第1期 242-265页

作者： gabriella e.pia

The early Bronze Age settlement at Ostiano *** is located on afluvial terrace at the confluence of the rivers Oglio and *** site produced evidenceof an archaeological layer,pits and post *** prehistoric structures yielded pottery and flint artefacts attributable to a local aspectof the Polada Culture,while no Middle Bronze Age potsherds or handles,arise ad ascia forinstance,have been found so *** chronological sequence of the pits seems to be asfollows:5,3,Ⅳ,Ⅰ,Ⅱ and Ⅲ.Pits 1 and 4 might be contemporary to each *** produced a small amount of *** results will be available when thestudy of all the structures will be *** faunal remains show that a well balanced economy was practised at the ***,sheep/goat and pig,in descending order,were the animals killed for meat.A scarcehunting activity is attested by red deer and roe deer *** data slightly differfrom those from the other Po Plain eBA sites from where there is evidence of a prevailingpig *** were also cultivated as revealed by the presence of burnt seeds andsickle blades made from *** at Ostiano *** also collected wild plants.A few pieces of daub indicate that the buts had wooden and clay *** greatvariety of vessels produced by the pits might suggest that pottery was locally *** contrary the flint artefacts are very rare,being composed of 28 tools *** bronzeimplements are extremely *** actually do not know whether this is due to thedistance of the site from the ore veins or to the various activities practised at differentsites complementary to each *** eBA settlement closed to *** is Cella Dati which also produced a few MBAsherds.

关键词： Pi DeL BRONZO AD OSTIANO LOCALIT SAN SALVATORe Nota preliminare sulla campagna dell’agosto 1980 STAZIONe DeLL’ANTICA eT CReMONA La

Methionine sources and genotype affect embryonic intestinal development, antioxidants, tight junctions, and growth-related gene expression in chickens

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Animal Nutrition 2024年第1期16卷 218-230页

作者： James K.Lugata Sawadi F.Ndunguru Gebrehaweria K.Reda Xénia e.Ozsváth eszter Angyal Levente Czeglédi gabriella Gulyás Renáta Knop János Oláh Zoltán Mészár Rita Varga Brigitta Csernus Csaba Szabó Department of Animal Nutrition and Physiology Faculty of Agriculture and Food Sciences and Environmental Management University of Debrecen Faculty of Agriculture and Food Sciences and environmental Management Doctoral School of Animal Science University of Debrecen Department of Animal Husbandry Faculty of Agriculture and Food Sciences and Environmental Management University of Debrecen Department of evolutionary Zoology and Human Biology Faculty of Science and Technology University of Debrecen Institutes for Agricultural Research and educational Farm University of Debrecen Department of Anatomy Histology and Embryology Faculty of Medicine University of Debrecen

Methionine(Met) is an essential and first limiting amino acid in the poultry diet that plays a significant role in chicken embryonic development and growth. The present study examined the effect of in ovo injection of DL-Met and L-Met sources and genotypes on chicken embryonic-intestinal development and health. Fertilized eggs of the two genotypes, TeTRA-SL layer hybrid(TSL)—commercial layer hybrid and Hungarian Partridge colored hen breed(HPC)—a native genotype, were randomly distributed into four treatments for each genotype. The treatment groups include the following: 1) control non-injected eggs(NoIn); 2) saline-injected(SaIn); 3) DL-Met injected(DLM); and 4) L-Met injected(LM). The in ovo injection was carried out on 17.5 d of embryonic development; after hatching, eight chicks per group were sacrificed, and the jejunum was extracted for analysis. The results showed that both DLM and LM groups had enhanced intestinal development as evidenced by increased villus width, villus height, and villus area(P ed to the control. The DLM group had significantly reduced crypt depth, glutathione(GSH) content, glutathione S-transferase 3 alpha(GST3), occludin(OCLN) gene expression and increased villus height to crypt depth ratio in the TSL genotype than the LM group(P e HPC genotype has overexpressed insulin-like growth factor 1(IGF1) gene, tricellulin(MD2), occludin(OCLN),superoxide dismutase 1(SOD1), and GST3 genes than the TSL genotype(P ese findings showed that in ovo injection of Met enhanced intestinal development, and function, with genotypes responding differently under normal conditions. Genotypes also influenced the expression of intestinal antioxidants, tight junction, and growth-related genes.

关键词： DL-Methionine L-Methionine In ovo injection Intestinal development Poultry

Social determinants of gastrointestinal malformation mortality in Brazil:a national study

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World Journal of Pediatric Surgery 2024年第2期7卷 134-141页

作者： Ayla Gerk Amanda Rosendo Luiza Telles Aricia Gomes Miranda Madeleine Carroll Bruna Oliveira Trindade Sarah Bueno Motter esther Freire gabriella Hyman Julia Ferreira Fabio Botelho Roseanne Ferreira David P Mooney Joaquim Bustorff-Silva Program in Global Surgery and Social Change Harvard Medical SchoolBostonMassachusettsUSA Faculty of Medicine and Health Sciences McGill UniversityMontrealQuebecCanada Harvey e.Beardmore Division of Pediatric Surgery The Montreal Children's HospitalMcGill University Health CentreMontrealQuebecCanada Department of Surgery Universidade Estadual de Campinas(UNICAMP)CampinasBrazil Instituto de educação Médica(IDOMeD/estácio Campus Vista Carioca)Rio de JaneiroBrazil Faculty of Medicine Universidade Federal do Delta do ParnaibaParnaibaPiauiBrazil Universidade Federal de Ciencias da Saude de Porto Alegre Porto AlegreBrazil Universidade Federal da Bahia SalvadorBrazil Department of Health Research Methods McMaster UniversityHamiltonSouthern OntarioCanada Department of Pediatric Surgery Boston Children's HospitalBostonMassachusettsUSA

Introduction In Brazil,approximately 5%are born with a congenital disorder,potentially fatal without *** study aims to evaluate the relationship between gastrointestinal congenital malformation(GICM)mortality,health indicators,and socioeconomic factors in *** GICM admissions(Q39-Q45)between 2012 and 2019 were collected using national *** demographics,socioeconomic factors,clinical management,outcomes,and the healthcare workforce density were also accounted *** Surgical Workforce density and the number of neonatal intensive care units in a region were extracted from national datasets and combined to create a clinical index termed'NeoSurg'.Socioeconomic variables were combined to create a socioeconomic index termed Socecon'.Simple linear regression was used to investigate if the temporal changes of both indexes were *** correlation between mortality and the different indicators in Brazil was evaluated using Pearson's correlation *** Over 8 years,Brazil recorded 12804 GICM *** Southeast led with 6147 cases,followed by the Northeast(2660),South(1727),North(1427),and Midwest(843).The North and Northeast reported the highest mortality,lowest NeoSurg,and Socecon Index ***,mortality rates declined across regions from 7.7%(2012)to 3.9%(2019),a 51.7%*** North and Midwest experienced the most substantial reductions,at 63%and 75%,*** significantly correlated with the indexes in nearly all regions(pe correlation between social determinants of health and GICM mortality in Brazil,using two novel indexes in the pediatric *** findings provide an opportunity to rethink and discuss new indicators that could enhance our understanding of our country and could lead to the development of necessary solutions to tackle existing challenges in Brazil and globally.

关键词： Northeast Brazil globally

Proposed GSSP for the base of Cambrian Stage 9,coinciding with the first appearance of Agnostotes orientalis, at Duibian, Zhejiang, China

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Science China earth Sciences 2009年第4期52卷 434-451页

作者： Loren e. BABCOCK gabriella BAGNOLI School of earth Sciences The Ohio State University Department of earth Sciences of Pisa University

exposed in natural outcrops near the Duibian Village, Jiangshan County, Zhejiang Province, China, the Duibian B section is proposed as the boundary stratotype for the base of an unnamed stage termed provisionally Cambrian Stage 9. The proposed position of the GSSP is 108.12 m above the base of the Huayansi Formation, at a horizon coinciding with the first appearance of the cosmopolitan agnostoid trilobite Agnostotes orientalis. This horizon coincides also with the first appearance of the cosmopoli-tan polymerid trilobite Irvingella angustilimbata. The section fulfills all the requirements for a GSSP, and the horizon can be constrained not only by the primary stratigraphic marker (A. orientalis) but also with secondary biostratigraphic, chemostratigraphic, and sequence-stratigraphic correlation tools. The first appearance of A. orientalis is one of the most readily recognizable levels in Cambrian, and can be correlated with precision to all paleocontinents.

关键词： Cambrian GSSP FAD of Agnostotes orientalis China chronostratigraphy

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The interrill erosion for a sandy loam soil

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International Journal of Sediment Research 2013年第3期28卷 329-337页

作者： gabriella BALACCO Dipartimento di Ingegneria Civile Ambientaledel TerritorioEdile e di Chimica(DICATECh)Politecnico di BariBari Italy

This paper resumes a laboratory experience on a slope adjustable plot with the aim of examining the role of rainfall intensity and slope gradient for a sandy loam soil,typical of Southern Italy,with particular initial moisture *** results of the simulations performed show that a rainfall reduction causes a corresponding percentage reduction of sediment output.A similar behaviour can be attributed to slope gradient,while runoff moderately increases with rainfall intensity but it is not sensitive to slope *** also highlight that the degree of saturation can affect runoff and soil loss values.

关键词： Interrill erosion Runoff Slope gradient

Numerical entropy andAdaptivity for FiniteVolume Schemes

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Communications in Computational Physics 2011年第10期10卷 1132-1160页

作者： gabriella Puppo Matteo Semplice Dipartimento di Matematica Politecnico di TorinoCorso Duca degli Abruzzi 2410129 TorinoItalia Dipartimento di Fisica e Matematica Universit`a dell’InsubriaVia Valleggio 1122100 ComoItalia

We propose an a-posteriori error/smoothness indicator for standard semidiscrete finite volume schemes for systems of conservation laws,based on the numerical production of *** idea extends previous work by the first author limited to central finite volume schemes on staggered *** prove that the indicator converges to zero with the same rate of the error of the underlying numerical scheme on smooth flows under grid *** construct and test an adaptive scheme for systems of equations in which the mesh is driven by the entropy *** adaptive scheme uses a single nonuniform grid with a variable *** show how to implement a second order scheme on such a space-time non uniform grid,preserving accuracy and conservation *** also give an example of a p-adaptive strategy.

关键词： Finite volume schemes hyperbolic systems local grid refinement entropy

An Implicit Scheme for Moving Walls and Multi-Material Interfaces in Weakly Compressible Materials

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Communications in Computational Physics 2020年第1期27卷 116-144页

作者： emanuela Abbate Angelo Iollo gabriella Puppo Universit`a degli Studi dell’Insubria via ValleggioComo 22100Italy Universit́e Bordeaux IMBUMR 5251F-33400 TalenceFrance equipe-projet Memphis Inria Bordeaux-Sud OuestF-33400 TalenceFrance La Sapienza Universit`a di Roma Piazzale Aldo Moro00185 RomaItaly

We propose a numerical method for the simulation of flows from weakly compressible to low Mach regimes in domains with moving ***-miscible weakly compressible materials separated by an interface are included as *** scheme is fully implicit and it exploits the relaxation all-speed scheme introduced in[1].We consider media with significantly different physical properties and constitutive laws,as fluids and hyperelastic *** proposed numerical scheme is fully eulerian and it is the same for all *** present numerical validations by simulating weakly compressible fluid/fluid,solid/solid and solid/fluid interactions.

关键词： Multi-material interfaces moving boundaries low Mach regime eulerian elasticity

Improving the Hydromechanical Deep-Drawing Process Using Aluminum Tailored Heat Treated Blanks

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Acta Metallurgica Sinica(english Letters) 2015年第12期28卷 1482-1489页

作者： Antonio Piccininni gabriella Di Michele Gianfranco Palumbo Donato Sorgente Luigi Tricarico Dipartimento di Meccanica Matematica e Management Politecnico di Bari

The present work demonstrates the effectiveness of combining the hydromechanical deep-drawing process with the Tailored Heat Treated Blank（THTB） technique. In the hydromechanical deep-drawing process, the fluid pressure is used for postponing the fracture occurrence in the blank, while the THTB technique allows to create a material property gradient through a suitable artificial aging treatment carried out prior to the forming process. Since the number of process variables is large, in the present work the authors propose an optimization loop for the determination of the parameters controlling the extension of the blank regions to be subjected to the aging treatment and the temperature levels to be set during the heat treatment. The proposed methodology couples a simple finite element model（Abaqus） with a multiobjective optimization platform（mode FRONTIeR）. A preliminary experimental campaign was carried out for determining the effect of the aging treatment on the mechanical（through tensile tests） and deformative（through formability tests）behavior of the AC170 PX aluminum alloy. Optimization results prove the effectiveness of the adopted methodology and put in evidence that the adoption of properly aged blanks in the hydromechanical deep drawing allows to increase the limit drawing ratio and to simplify the process since it is conducted at room temperature.

关键词： Aluminum alloy Aging Hydromechanical deep drawing Finite element analysis Mechanical characterization Formability

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CD28 ligation increases macrophage suppression of T-cell proliferation

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Cellular & Molecular Immunology 2012年第4期9卷 341-349页

作者： Daniel Silberman Amanda Bucknum Thomas Bartlett gabriella Composto Megan Kozlowskil Amanda Walker Amy Werda Jackelyn Cua Arlene H Sharpe John e Somerville James e Riggs Department of Biology Rider University Lawrenceville NJ 08648 USA Department of Pathology Harvard Medical School Cambridge MA 02115 USA Immunosciences Bristol-Myers Squibb Princeton NJ 08543 USA

When compared to spleen or lymph node cells, resident peritoneal cavity cells respond poorly to T-cell activation in vitro. The greater proportional representation of macrophages in this cell source has been shown to actively suppress the T-cell response. Peritoneal macrophages exhibit an immature phenotype （MHC class IIlo, B7lo） that reduces their efficacy as antigen-presenting cells. Furthermore, these cells readily express inducible nitric oxide synthase （iNOS）, an enzyme that promotes T-cell tolerance by catabolism of the limiting amino acid arginine. Here, we investigate the ability of exogenous T-cell costimulation to recover the peritoneal T-cell response. We show that CD28 ligation failed to recover the peritoneal T-cell response and actually suppressed responses that had been recovered by inhibiting iNOS. As indicated by cytokine eLISpot and neutralizing monoclonal antibody （mAb） treatment, this ＇cosuppression＇ response was due to CD28 ligation increasing the number of interferon （IFN）-y-secreting cells. Our results illustrate that cellular composition and cytokine milieu influence T-cell costimulation biology.

关键词： CD28 costimulation macrophages suppression

The resilience of pollination interactions: importance of temporal phases

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Journal of Plant ecology 2019年第1期12卷 157-162页

作者： edy Fantinato Silvia Del Vecchio Carlo Gaetan gabriella Buffa Department of environmental Sciences Informatics and StatisticsCa’Foscari University of VeniceVia Torino 15530172 VeniceItaly

Aims The loss of species that engage in close ecological interactions,such as pollination,has been shown to lead to secondary extinctions,ultimately threatening the overall ecosystem stability and *** studies are currently flourishing at all possible levels of interaction organization(i.e.,species,guild,group and network),and different methodological protocols aimed to define the resil-ience of pollination interactions have been ***,the temporal dimension of the resilience of pollination interactions has been often *** the light of these considerations,we addressed the following questions:does a temporal approach help to reveal critical moments during the flowering season,when polli-nation interactions are less resilient to perturbations?Do pollination interactions evaluated at species,guild,group and network level show different patterns when assessed through time?Methods We monitored contacts between plant and pollinator species in dry grassland communities every 15 days during the overall community flowering season(12 surveys).For each survey,we built a quantita-tive plant-pollinator interaction matrix and we calculated two sets of metrics characterizing,respectively,the diversity and the distribution of interactions across hierarchical *** describe the diversity of interactions,we calculated partner diversity(PD)at the species level,vulnerability/generality(V/G)at the guild level,and interaction diver-sity and evenness at the network *** distribution of interactions was characterized by calculating selectiveness at the species and the network level,and modularity at the group *** assessed the temporal variation of PD,V/G at the level of plants and pollinators,and species selectiveness,by means of Linear Mixed Models(LMMs).To investigate the temporal variation of indexes calculated at group and network level,we applied simple linear and quadratic regres-sions after checking for temporal autocorrelation

关键词： asymmetry complementarity ecosystems’resilience redundancy species-rich ecosystems