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A Case-Control Study on Leisure Time Physical Activity (LTPA) during the Last Three Months of Pregnancy and Foetal Outcomes in Italy

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Health 2016年第2期8卷 133-143页

作者： Guglielmina Fantuzzi Elena Righi gabriella aggazzotti Department of Biomedical Metabolic and Neural Sciences University of Modena and Reggio Emilia Modena Italy

The association between Leisure Time Physical Activity (LTPA) during pregnancy and foetal outcomes has been extensively investigated. However, epidemiological studies specifically referred to LPTA in the last months of pregnancy are scarce. We evaluated the association between LPTA and the risk of both preterm delivery and small for gestational age (SGA) during the last three months of pregnancy in Italy. A nationwide case-control study was performed in nine Italian cities. A total of 299 preterm delivery, 364 SGA and 855 controls were enrolled in the study. A self-administered questionnaire was used to assess socio-demographic variables, medical and reproductive history, life-style habits and LTPA referred to the last three months of pregnancy. Univariate and multivariate regression analyses were performed in order to estimate Odds ratios and 95% CI. LTPA during the last three months of pregnancy decreases the risk of preterm delivery (adjusted OR = 0.56;95% CI 0.39 - 0.79). Among the different types of physical activity, walking, the most frequently referred activity, appears significantly protective against preterm delivery (adjusted OR = 0.53;95% CI 0.36 - 0.81). Moreover, a small protective effect of walking was evidenced against SGA (adjusted OR = 0.72;95% CI 0.51 - 1.00). In conclusion, a mild physical activity such as walking in the last three months of pregnancy seems to reduce the risk of preterm delivery and, at a lesser extent, of SGA, confirming the beneficial effects of physical activity along the whole pregnancy.

关键词： Leisure Time Physical Activity (LTPA) Preterm Delivery Small for Gestational Age Last Three Months of Pregnancy Case Control Study

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Advances in Wireless,Batteryless,Implantable Electronics for Real‑Time,Continuous Physiological Monitoring

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Nano-Micro Letters 2024年第3期16卷 254-302页

作者： Hyeonseok Kim Bruno Rigo gabriella Wong Yoon Jae Lee Woon‑Hong Yeo IEN Center for Wearable Intelligent Systems and Healthcare Georgia Institute of TechnologyAtlantaGA 30332USA George W.Woodruff School of Mechanical Engineering Georgia Institute of TechnologyAtlantaGA 30332USA School of Electrical and Computer Engineering Georgia Institute of TechnologyAtlantaGA 30332USA Wallace H.Coulter Department of Biomedical Engineering Georgia Tech and Emory University School of MedicineAtlantaGA 30332USA Parker H.Petit Institute for Bioengineering and Biosciences Institute for MaterialsInstitute for Robotics and Intelligent MachinesGeorgia Institute of TechnologyAtlantaGA 30332USA

This review summarizes recent progress in developing wireless,batteryless,fully implantable biomedical devices for real-time continuous physiological signal monitoring,focusing on advancing human health *** considerations,such as biological constraints,energy sourcing,and wireless communication,are discussed in achieving the desired performance of the devices and enhanced interface with human *** addition,we review the recent achievements in materials used for developing implantable systems,emphasizing their importance in achieving multi-functionalities,biocompatibility,and *** wireless,batteryless devices offer minimally invasive device insertion to the body,enabling portable health monitoring and advanced disease ***,we summarize the most recent practical applications of advanced implantable devices for human health care,highlighting their potential for immediate commercialization and clinical uses.

关键词： Implantable electronics Biomedical systems Batteryless devices Wireless electronics Physiological signal monitoring

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How Music Intervention Lowered Participants’ Morning Cortisol—Qualitative Case Stories

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Case Reports in Clinical Medicine 2024年第6期13卷 193-206页

作者： Töres Theorell gabriella Engstrom Azita Emami Division of Global Health Karolinska Institutet Stockholm Sweden Stress Research Institute Department of Psychology Stockholm University Stockholm Sweden School of Health and Welfare Dalarna University Falun Sweden Division of Occupational Therapy Department of Neurobiology Care Sciences and Society Karolinska Institutet Stockholm Sweden Yale School of Nursing Yale University New Haven CT USA

Non-pharmacological interventions for improved home care of persons with dementia and their family caregiver are and will be increasingly important for society. A music intervention study was performed on persons with persons with dementia and family caregiver. The persons with dementia and family caregiver were instructed to choose a daily routine for joint listening to recorded music. They selected the music they were interested in from a menu. The intervention period lasted for two months. Both persons with dementia and family caregiver provided daily saliva samples for the assessment of stress-related steroid hormones. In previous reports we have reported that the morning cortisol levels decreased significantly among the family caregiver when the intervention group was compared to a control group. In the present study we report narratives from four dyads, two of whom with beneficial effects of the music intervention, one dyad with no clear beneficial effects and one dyad with mixed results. The narratives illustrate the strong cohesive effect that the joint music listening could have, leading to improved social functioning paralleled by decreased morning cortisol levels particularly in the family caregiver. The narratives also illustrate reasons for failed effects.

关键词： Dementia Family Caregivers Music Stress Saliva Morning Cortisol

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Effectiveness of Frequent Viral Load Testing Plus Additional Interventions to Prevent HIV Transmission in Heterosexual,Serodiscordant Couples—Yunnan Province,China,2019-2021

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China CDC weekly 2024年第27期6卷 658-664,I0001-I0004页

作者： Jing Han Jian Li Yuhua Shi Chunpeng Zang Zhimin Yang Yu Han Yanling Ma Qiongli Duan Yuhua Hu Zikuang Bai Cuiyun Yang gabriella Bulloch Yurong Mao Houlin Tang Zunyou Wu Yufen Liu National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Yunnan Provincial Center for Disease Control and Prevention Kunming CityYunnan ProvinceChina Honghe Prefectural Center for Disease Control and Prevention Honghe CityYunnan ProvinceChina Wenshan Prefectural Center for Disease Control and Prevention Wenshan CityYunnan ProvinceChina Zhaotong Prefectural Center for Disease Control and Prevention Zhaotong CityYunnan ProvinceChina Lincang Prefectural Center for Disease Control and Prevention Lincang CityYunnan ProvinceChina Faculty of Medicine Dentistry and Health SciencesUniversity of MelbourneMelbourneVICAustralia

Summary What is already known about this topic?HIV transmission among serodiscordant couples remains a persistent issue in ***,the practice of combining counseling with antiretroviral therapies(ART)to enhance ART adhe... 详细信息

关键词： China. ant discord

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Methionine sources and genotype affect embryonic intestinal development,antioxidants,tight junctions,and growth-related gene expression in chickens

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Animal Nutrition 2024年第1期16卷 218-230页

作者： James K.Lugata Sawadi F.Ndunguru Gebrehaweria K.Reda Xénia E.Ozsváth Eszter Angyal Levente Czeglédi gabriella Gulyás Renáta Knop János Oláh Zoltán Mészár Rita Varga Brigitta Csernus Csaba Szabó Department of Animal Nutrition and Physiology Faculty of Agriculture and Food Sciences and Environmental ManagementUniversity of DebrecenDebrecenHungary Department of Animal Husbandry Faculty of Agriculture and Food Sciences and Environmental ManagementUniversity of DebrecenDebrecenHungary Faculty of Agriculture and Food Sciences and Environmental Management Doctoral School of Animal ScienceUniversity of DebrecenDebrecenHungary Institutes for Agricultural Research and Educational Farm University of DebrecenDebrecenHungary Department of Anatomy Histology and EmbryologyFaculty of MedicineUniversity of DebrecenDebrecenHungary Department of Evolutionary Zoology and Human Biology Faculty of Science and TechnologyUniversity of DebrecenDebrecenHungary

Methionine(Met)is an essential and first limiting amino acid in the poultry diet that plays a significant role in chicken embryonic development and *** present study examined the effect of in ovo injection of DL-Met and L-Met sources and genotypes on chicken embryonic-intestinal development and *** eggs of the two genotypes,TETRA-SL layer hybrid(TSL)—commercial layer hybrid and Hungarian Partridge colored hen breed(HPC)—a native genotype,were randomly distributed into four treatments for each *** treatment groups include the following:1)control non-injected eggs(NoIn);2)saline-injected(SaIn);3)DL-Met injected(DLM);and 4)L-Met injected(LM).The in ovo injection was carried out on 17.5 d of embryonic development;after hatching,eight chicks per group were sacrificed,and the jejunum was extracted for *** results showed that both DLM and LM groups had enhanced intestinal development as evidenced by increased villus width,villus height,and villus area(P<0.05)compared to the *** DLM group had significantly reduced crypt depth,glutathione(GSH)content,glutathione S-transferase 3 alpha(GST3),occludin(OCLN)gene expression and increased villus height to crypt depth ratio in the TSL genotype than the LM group(P<0.05).The HPC genotype has overexpressed insulin-like growth factor 1(IGF1)gene,tricellulin(MD2),occludin(OCLN),superoxide dismutase 1(SOD1),and GST3 genes than the TSL genotype(P<0.05).In conclusion,these findings showed that in ovo injection of Met enhanced intestinal development,and function,with genotypes responding differently under normal *** also influenced the expression of intestinal antioxidants,tight junction,and growth-related genes.

关键词： DL-Methionine L-Methionine In ovo injection Intestinal development Poultry

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Advancing prognostic understanding in hepatocellular carcinoma through the integration of genomic instability and lncRNA signatures: GILncSig model

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World Journal of Gastrointestinal Surgery 2024年第9期16卷 2774-2777页

作者： Marco Bocchetti gabriella Misso Silvia Zappavigna Marianna Scrima Michele Caraglia Francesca Pentimalli Alessia Maria Cossu Department of Precision Medicine University of Campania“Luigi Vanvitelli”Naples 80138Italy Department of Molecular and Precision Oncology Biogem ScarlInstitute of Genetic ResearchAriano Irpino 83031Italy Department of Medicine and Surgery LUM University Giuseppe De GennaroCasamassima 70010Italy

The recently published study by Duan et al introduces a promising method that combines genomic instability and long non-coding RNAs to improve the prognostic evaluation of hepatocellular carcinoma(HCC),a deadly cancer associated with considerable morbidity and *** editorial aims to analyze the methodology,key findings,and broader implications of the study within the fields of gastroenterology and oncological surgery,highlighting the shift towards precision medicine in the management of HCC.

关键词： Genomic instability Long non-coding RNA Hepatocellular carcinoma Prognosis

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The interrill erosion for a sandy loam soil

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International Journal of Sediment Research 2013年第3期28卷 329-337页

作者： gabriella BALACCO Dipartimento di Ingegneria Civile Ambientaledel TerritorioEdile e di Chimica(DICATECh)Politecnico di BariBari Italy

This paper resumes a laboratory experience on a slope adjustable plot with the aim of examining the role of rainfall intensity and slope gradient for a sandy loam soil,typical of Southern Italy,with particular initial moisture *** results of the simulations performed show that a rainfall reduction causes a corresponding percentage reduction of sediment output.A similar behaviour can be attributed to slope gradient,while runoff moderately increases with rainfall intensity but it is not sensitive to slope *** also highlight that the degree of saturation can affect runoff and soil loss values.

关键词： Interrill erosion Runoff Slope gradient

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Mounting evidence of FKBP12 implication in neurodegeneration

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Neural Regeneration Research 2020年第12期15卷 2195-2202页

作者： gabriella Caminati Piero Procacci Department of Chemistry“Ugo Schiff” University of FlorenceSesto FiorentinoItaly Center for Colloid and Surface Science(CSGI) University of FlorenceSesto FiorentinoItaly

Intrinsically disordered proteins, such as tau or α-synuclein, have long been associated with a dysfunctional role in neurodegenerative diseases. In Alzheimer’s and Parkinson’s’ diseases, these proteins, sharing a common chemical-physical pattern with alternating hydrophobic and hydrophilic domains rich in prolines, abnormally aggregate in tangles in the brain leading to progressive loss of neurons. In this review, we present an overview linking the studies on the implication of the peptidyl-prolyl isomerase domain of immunophilins, and notably FKBP12, to a variety of neurodegenerative diseases, focusing on the molecular origin of such a role. The involvement of FKBP12 dysregulation in the aberrant aggregation of disordered proteins pinpoints this protein as a possible therapeutic target and, at the same time, as a predictive biomarker for early diagnosis in neurodegeneration, calling for the development of reliable, fast and cost-effective detection methods in body fluids for community-based screening campaigns.

关键词： Alzheimer’s disease biomarker detections FKBP12 FK506 binding protein neurodegeneration Parkinson’s disease tau protein α-synuclein

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Plasmon-enhanced rotational dynamics of anisotropic core-shell polymeric-metallic microparticles

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Photonics Research 2022年第12期10卷 2734-2742页

作者： NICOLA PELLIZZI ALFREDO MAZZULLA PASQUALE PAGLIUSI gabriella CIPPARRONE Physics Department University of Calabria87036 Rende(CS)Italy Cnr—Istituto di Nanotecnologia-sede secondaria di Rende(CS) Italy

The development of efficient and cost-effective micromachines is a challenge for applied and fundamental science,given their wide fields of *** is a suitable tool to move small objects in a noncontact way,given its capabilities in exerting forces and ***,when complex manipulation is required,micro-objects with proper architecture could play a specific *** we report on the rotational dynamics of core-shell particles,with a polymeric nematic core of ellipsoidal shape capped by Au *** undergo a peculiar synchronous spinning and orbital motion when irradiated by a simple Gaussian beam,which originates from the coupling of the metallic nanoparticles’optical response and the core *** rotation capabilities are strongly enhanced when the trapping wavelength lies in the plasmonic resonance region:indeed,the spin kinetic energy reaches values two orders of magnitude larger than the one of bare *** proposed strategy brings important insights into optimizing the design of light controlled micro-objects and might benefit applications in microfluidics,microrheology,and micromachining involving rotational dynamics.

关键词： metallic dynamics anisotropic

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Numerical Entropy andAdaptivity for FiniteVolume Schemes

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Communications in Computational Physics 2011年第10期10卷 1132-1160页

作者： gabriella Puppo Matteo Semplice Dipartimento di Matematica Politecnico di TorinoCorso Duca degli Abruzzi 2410129 TorinoItalia Dipartimento di Fisica e Matematica Universit`a dell’InsubriaVia Valleggio 1122100 ComoItalia

We propose an a-posteriori error/smoothness indicator for standard semidiscrete finite volume schemes for systems of conservation laws,based on the numerical production of *** idea extends previous work by the first author limited to central finite volume schemes on staggered *** prove that the indicator converges to zero with the same rate of the error of the underlying numerical scheme on smooth flows under grid *** construct and test an adaptive scheme for systems of equations in which the mesh is driven by the entropy *** adaptive scheme uses a single nonuniform grid with a variable *** show how to implement a second order scheme on such a space-time non uniform grid,preserving accuracy and conservation *** also give an example of a p-adaptive strategy.

关键词： Finite volume schemes hyperbolic systems local grid refinement entropy

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