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changes in acute and late toxicity and patient-reported health-related quality of life following radiotherapy in women with breast cancer:A 1-year longitudinal study

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Journal of Integrative Nursing 2024年第1期6卷 15-21页

作者： gonca Hanedan USLU Aydanur AYDIN Ayla gÜRSOY Department of Radiation Oncology Faculty of MedicineRecep Tayyip Erdogan UniversityRizeTurkey Department of Nursing Antalya Bilim UniversityFaculty of Health SciencesGumushane UniversityGumushaneTurkey Department of Nursing Faculty of Health SciencesAntalya Bilim UniversityAntalyaTurkey

Objective:The objective of this study was to investigate the frequency of acute and late toxicities,as well as changes in the quality of life(QOL)for breast cancer patients following radiotherapy(RT).Materials and Methods:A total of 108 breast cancer women were recruited for this prospective *** were collected at various intervals;prior to,and 1,3,6 months,and 1 year after radiation *** primary outcomes were toxicity radiation therapy oncology group/European Organization for Research and Treatment of cancer(EORTc)*** secondary outcome was QOL,measured using EORTc QLQ-c30 and Edmonton Symptom Assessment *** employed Friedman’s two-way analysis to evaluate the changes in QOL over the course of 1 ***:The early toxicities that are most commonly experienced include pharyngeal,skin,and mucous membrane *** toxicities frequently involve skin and submucosal *** measure patient functionality,all functional subscale scores except for the patient’s emotional state increased over time compared to *** of the patients,which were included in the QOL symptom scale,decreased during the follow-up period,except for fatigue;however,changes in pain,insomnia,and loss of appetite did not significantly *** identified the analogous symptom profiles in *** patients’overall health scores declined in the 1st and 3rd months after radiotherapy(RT),they rebounded at 6 and 12 ***:For breast cancer patients,RT did not adversely affect functional capacity or exacerbate symptoms,but persistent fatigue did increase during the observation ***-care professionals ought to devise strategies to assist patients with skin toxicity and fatigue.

关键词： Breast cancer health‑related quality of life radiotherapy toxicity

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carbon coated LaFe_(0.92)Pd_(0.08)O_(3) composites for catalytic transfer hydrogenation:Balance in the ability of substrates adsorption and conversion

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Nano Research 2024年第5期17卷 3724-3732页

作者： Bowen Wang Nan Zhang Ping Xiao Jian Zhang Sónia A.c.carabineiro Junjiang Zhu Hubei Key Laboratory of Biomass Fibers and Eco-dyeing&Finishing College of Chemistry and Chemical EngineeringWuhan Textile UniversityWuhan 430200China college of chemistry and Materials Engineering Wenzhou UniversityWenzhou 325035China LAQV-REQUIMTE Department of ChemistryNOVA School of Science and TechnologyUniversidade NOVA de LisboaLargo da Torre2829-516 CaparicaPortugal

catalytic transfer hydrogenation(cTH)is a green and efficient pathway for selective hydrogenation of unsaturated aldehydes and ***,managing the abilities of solid catalysts to adsorb substrates and to convert them into desired products is a challenging ***,we report the synthesis of carbon coated LaFe_(0.92)Pd_(0.08)O_(3) composites(LFPO-8@c)for cTH of benzaldehyde(BzH)into benzyl alcohol(BzOH),using isopropanol(IPA)as hydrogen *** coating with carbon improves the ability to adsorb/transfer reactants from solution to active sites,and the doping of Pd2+at Fe3+site strengthens the ability of LaFeO_(3) to convert BzH into BzOH.A balanced point between them(i.e.,abilities to adsorb BzH and to convert BzH into BzOH)is obtained at LFPO-8@c,which exhibits a BzOH formation rate of 3.88 mmol·gcat^(-1)·h^(-1) at 180℃ for 3 h,which is 1.50 and 2.72 times faster than those of LFPO-8 and LaFeO_(3)@c.A reaction mechanism is proposed,in which the acidic sites(e.g.,Fe^(4+),oxygen vacancy)are used for the activation of c=O bond of BzH and O-H bond of IPA,and the basic sites(e.g.,lattice oxygen)for the activation ofα-H(O-H)bond of IPA.

关键词： LaFe_(0.92)Pd_(0.08)O_(3) porous carbon catalytic transfer hydrogenation isopropanol reaction mechanism

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Impact of cOVID-19 pandemic on cardiovascular health in sedentary and athletes:consensus,uncertainties,and ways for mitigation

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Sports Medicine and Health Science 2024年第3期6卷 205-208页

作者： John c.Quindry Lei Xi School of Integrative Physiology and Athletic Training University of MontanaMissoulaMT59812USA Pauley Heart center Department of Internal MedicineSchool of MedicineVirginia Commonwealth UniversityRichmondVA23298-0204USA

More than 4 years has elapsed since the World Health Organization(WHO)ofﬁcially announced the coronavirus disease 2019(cOVID-19)as a pandemic outbreak in March 11,*** the ongoing investigations and political debates upon the origin,exacerbation,resurgence,andﬁnal control of cOVID-19,medical and scientiﬁc consensus indicates that the now endemic cOVID-19 virus is one of the worst public health crises in our *** every person on earth has been directly or indirectly impacted by the adverse effects of the highly contagious viral pathogen-SARS-coV-2(severe acute respiratory syndrome coronavirus 2).Indeed,the population reach of the cOVID-19 infection includes governmental response measures(e.g.,lockdowns and social distancing,mandates for masks and face coverings,vaccines,etc.)that have restricted entrenched societal routines,personal mobility,and ***,the host of health problems linked to this viral infection linger to this day,with selective groups of people experiencing a higher risk for untoward medical outcomes and/or elevated levels of vulnerability to the post-acute sequelae of cOVID-19(***-cOVID).For example,a 2021 study by Logue et *** initial evidence that 10%–30%of individuals in United States may experience prolonged symptoms following SARS-coV-2 infection,including cardiovascular abnormalities.1 Similarly,a 2021 retrospective cohort study in England suggest that the incidence of major adverse cardiovascular events(*** failure,myocardial infarction,ischemic stroke.

关键词： cardiovascular routine Impact

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Thermodynamic analysis of metal segregation in dual phase high entropy ceramics

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Journal of Materiomics 2024年第4期10卷 889-895页

作者： Steven M.Smith II William g.Fahrenholtz gregory E.Hilmas Stefano curtarolo Missouri University of Science and Technology Materials Science and Engineering DepartmentRollaMO65409USA Duke University Department of Mechanical Engineering and Materials ScienceDurhamNC27708USA Duke University Center of Autonomous Materials DesignDurhamNC27708USA

Equilibrium gibbs'free energy calculations were used to determine metal segregation trends between boride and carbide solid solutions containing two metals that are relevant to dual phase high entropy *** model predicted that Ti had the strongest tendency to segregate to the boride phase followed by Zr,Nb,Mo,V,Hf,and Ta,which matches experimental results of measured *** ratio of a metal in the carbide phase to the content of the same metal in the corresponding metal boride had a linear trend with the change in standard gibbs'free energy of reaction for a metal carbide reacting with B_(4)c to produce its corresponding metal boride and *** proposed model was used to predict the changes in standard gibbs'free energy for crc→crB_(2) to be−260 kJ and Wc→WB_(2) to be 148 kJ,which indicates that cr has the strongest segregation to the boride and W has the strongest segregation to the *** proposed model can be used to estimate the segregation of metals in dual phase high entropy boride-carbide ceramics of any boride/carbide ratio or metal content.

关键词： Dual phase High entropy ceramic Boride carbide Thermodynamics

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Adsorption of pharmaceutical pollutants on Zncl_(2)-activated biochar from corn cob:Efficiency,selectivity and mechanism

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Journal of Bioresources and Bioproducts 2024年第1期9卷 58-73页

作者： christian F.Varela L.c.Moreno-Aldana Yazmin Yaneth Agámez-Pertuz Department of chemistry National University of ColombiaAv.Carrera 30 No.45-03BogotáD.C.Colombia Department of Biology and chemistry University of the Llanoskm 12 road to Puerto LópezVillavicencioColombia

The occurrence of pharmaceuticals in water bodies and drinking water poses risks for the envi-ronment and human health,thus it is necessary to study methodologies that allow the efficient removal of these *** this work,corn cob-derived biochar was obtained by Zncl_(2)-activation,and subsequent carbonization at 700℃.The effect of contact time,temperature,pH,and initial concentration on the adsorption capacity of acetaminophen(AcE)and amoxicillin(AMX)was determined through batch *** addition,the kinetics,isotherms,and ther-modynamics parameters were *** activated biochar exhibited a maximum adsorp-tion capacity of 332.08 mg/g for AcE and 175.86 mg/g for *** adsorption kinetics and adsorption isotherm of AcE corresponded to the pseudo-second order and Langmuir model,***,pseudo-first-order kinetics and the Freundlich isotherm model were well-fitted to AMX *** AcE and AMX co-adsorption had a synergistic effect on AMX but an antagonistic effect on AcE removal,achieving a maximum adsorption capacity of 193.51 and 184.58 mg/g,*** the other hand,fixed-bed column experiments showed that the adsorption capacity depends on the influent concentration,and the breakthrough curve fits the Thomas and Yoon-Nelson *** mechanism adsorption studies showed that surface inter-actions(hydrogen bonding formation and n-𝜋interactions)are the main driving forces for the adsorption process,and pore filling is the rate-limiting *** this way,the prepared biochar exhibits a high potential for the adsorption of pharmaceutical compounds from water.

关键词： Biochar Adsorption Acetaminophen Amoxicillin Wastewater treatment

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The storage and utilization of carbohydrates in response to elevation mediated by tree organs in subtropical evergreen broad-leaved forests

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Forest Ecosystems 2024年第1期11卷 52-61页

作者： Bin Xu Xueli Jiang Yingying Zong g.geoff Wang Fusheng chen Zhenyu Zhao Xiangmin Fang Key Laboratory of National Forestry and grassland Administration on Forest Ecosystem Protection and Restoration of Poyang Lake Watershed College of ForestryJiangxi Agricultural UniversityNanchang330045China Jiulianshan National Observation and Research Station of chinese Forest Ecosystem College of ForestryJiangxi Agricultural UniversityNanchang330045China Department of Forestry and Environmental conservation Clemson UniversityClemsonSC29634USA

global climate change can affect tree growth and carbon sink function by influencing plant carbohydrate synthesis and utilization,while elevation can be used as an ideal setting under natural conditions to simulate climate change *** effect of elevation on tree growth may depend on organ ***,the allocation patterns of nonstructural and structural carbohydrates(NScs and Scs,respectively)in different tree organs and their response to elevation remain *** selected four dominant tree species,Schima superba,castanopsis eyrei,castanopsis fargesii and Michelia maudiae,along an elevation gradient from 609 to 1,207 m in subtropical evergreen broad-leaved forests and analyzed leaf,trunk,and fine root NScs,carbon(c),nitrogen(N)and phosphorus(P)concentrations and the relative abundance of *** NScs increased initially and then decreased,and trunk NScs increased with increasing ***,root NScs decreased with increasing *** relative abundance of Scs in leaves and trunks decreased,while the relative abundance of root Scs increased with increasing *** significant correlations between Scs and NScs in leaves were detected,while there were negative correlations between Scs and NScs in trunks,roots,and all *** partitioning analysis indicated that plant c/N and c/P were the main predictors of changes in Scs and *** results suggest that tree organs have divergent responses to elevation and that increasing elevation will inhibit the aboveground part growth and enhance the root growth of trees.A tradeoff between the c distribution used for growth and storage was confirmed along the elevation gradient,which is mainly manifested in the"sink"organs of *** results provide insight into tree growth in the context of global climate change scenarios in subtropical forest ecosystems.

关键词： Nonstructural carbohydrates Structural carbohydrates Elevation Subtropical evergreen broad-leaved forests Tree organs

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Postbiotics from Saccharomyces cerevisiae fermentation stabilize microbiota in rumen liquid digesta during grain-based subacute ruminal acidosis(SARA) in lactating dairy cows

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Journal of Animal Science and Biotechnology 2024年第5期15卷 2059-2080页

作者： Junfei guo Zhengxiao Zhang Le Luo guan Ilkyu Yoon Jan c.Plaizier Ehsan Khafipour Department of Animal Science University of ManitobaWinnipegMB R3T 2N2Canada Present Address:college of Food and Biological Engineering Jimei UniversityXiamenFujian 361021China Department of Agriculture Food and Nutrition DepartmentUniversity of AlbertaEdmontonAB T6G 2R3Canada Faculty of Land and Food Systems University of British ColumbiaVancouverBC V6T 1Z4Canada Diamond V Cedar RapidsIA 52404United States Present Address:cargill Animal Nutrition 15407 McGinty Road WestWayzataMN 55391USA

Background Subacute ruminal acidosis(SARA)is a common metabolic disorder of high yielding dairy cows,and it is associated with dysbiosis of the rumen and gut microbiome and host *** study evaluated the impact of two postbiotics from Saccharomyces cerevisiae fermentation products(ScFP)on rumen liquid associated microbiota of lactating dairy cows subjected to repeated grain-based SARA challenges.A total of 32 rumen cannulated cows were randomly assigned to 4 treatments from 4 weeks before until 12 weeks after *** groups included a control diet or diets supplemented with postbiotics(ScFPa,14 g/d Original XPc;ScFPb-1X,19 g/d Nutri Tek;ScFPb-2X,38 g/d Nutri Tek,Diamond V,cedar Rapids,IA,USA).grain-based SARA challenges were conducted during week 5(SARA1)and week 8(SARA2)after parturition by replacing 20%DM of the base total mixed ration(TMR)with pellets containing 50%ground barley and 50%ground *** DNA from rumen liquid samples was subjected to V3–V416S r RNA gene amplicon *** of rumen microbiota were compared among treatments and SARA *** Both SARA challenges reduced the diversity and richness of rumen liquid microbiota,altered the overall composition(β-diversity),and its predicted functionality including carbohydrates and amino acids metabolic *** SARA challenges also reduced the number of significant associations among different taxa,number of hub taxa and their composition in the microbial co-occurrence *** with ScFP postbiotics,in particular ScFPb-2X,enhanced the robustness of the rumen *** ScFP supplemented cows had less fluctuation in relative abundances of community members when exposed to SARA *** ScFP supplementation promoted the populations of lactate utilizing and fibrolytic bacteria,including members of Ruminococcaceae and Lachnospiraceae,and also increased the numbers of hub taxa during non-SARA and SARA *** with S

关键词： Postbiotics Rumen microbiota Saccharomyces cerevisiae fermentation products SARA

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Synthetic high-density lipoprotein(sHDL):a bioinspired nanotherapeutics for managing periapical bone inflammation

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International Journal of Oral Science 2024年第3期16卷 460-470页

作者： Renan Dal-Fabbro Minzhi Yu Ling Mei Hajime Sasaki Anna Schwendeman Marco c.Bottino Department of cariology Restorative Sciencesand EndodonticsSchool of DentistryUniversity of MichiganAnn ArborMIUSA Department of Pharmaceutical Sciences College of Pharmacy and Biointerfaces InstituteUniversity of MichiganAnn ArborMIUSA Department of Biomedical Engineering College of EngineeringUniversity of MichiganAnn ArborMIUSA

Apical periodontitis(AP)is a dental-driven condition caused by pathogens and their toxins infecting the inner portion of the tooth(i.e.,dental pulp tissue),resulting in inflammation and apical bone resorption affecting 50%of the worldwide population,with more than 15 million root canals performed annually in the United *** treatment involves cleaning and decontaminating the infected tissue with chemo-mechanical approaches and materials introduced years ago,such as calcium hydroxide,zinc oxide–eugenol,or even formalin ***,we present,for the first time,a nanotherapeutics based on using synthetic highdensity lipoprotein(sHDL)as an innovative and safe strategy to manage dental bone *** application in concentrations ranging from 25μg to 100μg/mL decreases nuclear factor Kappa B(NF-κB)activation promoted by an inflammatory stimulus(lipopolysaccharide,LPS).Moreover,sHDL at 500μg/mL concentration markedly decreases in vitro osteoclastogenesis(Pction in an inflammatory ***,sHDL strongly dampens the Toll-Like Receptor signaling pathway facing LPS stimulation,mainly by downregulating at least 3-fold the pro-inflammatory genes,such as Il1b,Il1a,Il6,Ptgs2,and *** vivo,the lipoprotein nanoparticle applied after NaOcl reduced bone resorption volume to(1.3±0.05)mm^(3) and attenuated the inflammatory reaction after treatment to(1090±184)cells compared to non-treated animals that had(2.9±0.6)mm^(3)(P=0.0123)and(2443±931)cells(P=0.004),thus highlighting its promising clinical potential as an alternative therapeutic for managing dental bone inflammation.

关键词： inflammation lipoprotein markedly

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A review on the parasitic isopod genus Notophryxus ***,1883(crustacea:Isopoda),and first report of Notophryxus globularis ***,1885 from Lakshadweep Sea(Amini Island)

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Acta Oceanologica Sinica 2024年第8期43卷 142-153页

作者： Mukkattu Nazar Suhaana Jaime gómez-gutiérrez Paravanparambil Rajakumar Jayachandran Punnakkal Hari Praved Sivasankaran Bijoy Nandan Department of Marine Biology Microbiology and BiochemistrySchool of Marine SciencesCochin University of Science and TechnologyKochi-Kerala 682016India Departamento de Plancton y Ecología Marina Centro Interdisciplinario de Ciencias MarinasInstituto Politécnico NacionalLa Paz B.C.S.23096Mexico Applied Research centre for Environment and Marine Studies King Fahd University of Petroleum and MineralsDhahran 31261Saudi Arabia

Isopod crustaceans of the family Dajidae are exclusively marine *** genus Notophryxus ***,1883 currently includes nine nominal species,which are very rarely reported as the chances for encountering these specimens are *** comprehension of the taxonomy,biology,ecology,and life cycle of species belonging to the Notophryxus genus is notably *** nominal species of Notophryxus genus are reviewed here to obtain a comprehensive and integrative taxonomic understanding of this genus,in an attempt to address the *** paper also documents the rediscovery of an ectoparasitic isopod from the genus Notophryxus in Indian waters,after 55 *** isopod specimens obtained from the outer reefs of Amini Island in the Lakshadweep archipelago,Southeastern Arabian Sea,display morphological congruence to Notophryxus globularis ***,*** only previous report on this species dates back to 1885 from ***'description of *** as an ectoparasite on the euphausiid Thysanoessa gregaria ***,1883 in the North *** discovery represents a range extension of *** from the North Pacific to the Arabian *** cryptoniscid larvae and three adult females of ***(with dwarf males)were found attached to four adult mysid specimens of Siriella aequiremis Hansen,*** present study provides an improved diagnosis of *** with the aid of light microscopy images and line drawings which was not given in the original ***,1885 *** research also provides a concise description of cryptoniscid larvae from the same sampling location and same host which is most likely to be *** larvae.

关键词： Dajiidae Mysid cryptoniscan larvae Southeastern Arabian Sea Notophryxus

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Isochrone Fitting of galactic globular clusters—Ⅵ.High-latitude clusters Ngc 5024 (M53),Ngc 5053,Ngc 5272 (M3),Ngc 5466,and Ngc7099 (M30)

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Research in Astronomy and Astrophysics 2024年第6期24卷 170-190页

作者： g.A.gontcharov S.S.Savchenko A.A.Marchuk c.J.Bonatto O.S.Ryutina M.Yu.Khovritchev V.B.Il'in A.V.Mosenkov D.M.Poliakov A.A.Smirnov central(Pulkovo)Astronomical Observatory Russian Academy of SciencesPulkovskoye chaussee 65/1St.Petersburg 196140Russia Saint Petersburg State University Universitetskij pr.28St.Petersburg 198504Russia Special Astrophysical Observatory Russian Academy of Sciences369167 Nizhnij ArkhyzRussia Departamento de Astronomia Instituto de FísicaUFRGSAv.Bento Gonçalves9500Porto AlegreRSBrazil Saint Petersburg University of Aerospace Instrumentation Bol.Morskaya ul.67ASt.Petersburg 190000Russia Department of Physics and Astronomy Brigham Young UniversityN283 ESCProvoUT 84602USA

We fit various color–magnitude diagrams(cMDs) of the high-latitude galactic globular clusters Ngc 5024(M53),Ngc 5053,Ngc 5272(M3),Ngc 5466,and Ngc 7099(M30) by isochrones from the Dartmouth Stellar Evolution Database and Bag of Stellar Tracks and Isochrones for α–enrichment [α/Fe] = +*** the cMDs,we use data sets from Hubble Space Telescope,gaia,and other sources utilizing,at least,25 photometric filters for each *** obtain the following characteristics with their statistical uncertainties for Ngc 5024,Ngc 5053,Ngc 5272,Ngc 5466,and Ngc 7099,respectively:metallicities [Fe/H] =-1.93 ± 0.02,-2.08 ± 0.03,-1.60 ± 0.02,-1.95 ± 0.02,and-2.07 ± 0.04 dex with their systematic uncertainty 0.1 dex;ages 13.00 ± 0.11,12.70 ± 0.11,11.63 ± 0.07,12.15 ± 0.11,and 12.80 ± 0.17 gyr with their systematic uncertainty 0.8 gyr;distances(systematic uncertainty added) 18.22 ± 0.06 ± 0.60,16.99 ± 0.06 ± 0.56,10.08 ± 0.04 ± 0.33,15.59 ±0.03 ± 0.51,and 8.29 ± 0.03 ± 0.27 kpc;reddenings E(B-V) = 0.023 ± 0.004,0.017 ± 0.004,0.023 ± 0.004,0.023 ± 0.003,and 0.045 ± 0.002 mag with their systematic uncertainty 0.01 mag;extinctions AV= 0.08 ± 0.01,0.06 ± 0.01,0.08 ± 0.01,0.08 ± 0.01,and 0.16 ± 0.01 mag with their systematic uncertainty 0.03 mag,which suggest the total galactic extinction AV= 0.08 across the whole galactic dust to extragalactic objects at the North galactic *** horizontal branch morphology difference of these clusters is explained by their different metallicity,age,mass-loss efficiency,and loss of low-mass members in the evolution of the core-collapse cluster Ngc 7099 and loose clusters Ngc 5053 and Ngc 5466.

关键词： (stars:)Hertzsprung Russell and c-M diagrams (ISM:)dust extinction (galaxy:)globular clusters:general (galaxy:)globular clusters:individual(Ngc 5024,Ngc 5053,Ngc 5272,Ngc 5466,Ngc7099)

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