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混凝土破损结构的补偿收缩修补砂浆

膨胀剂与膨胀混凝土 2007年第4期 21-25页

作者： S.Collepardi g.corazza g.Fazio S.Monosi R.Troli 刘立

关键词：膨胀剂修补砂浆减缩剂

Methodology and evidence from a case study in Rome to increase pedestrian safety along home-to-school routes

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Journal of Traffic and Transportation Engineering(English Edition) 2020年第5期7卷 715-727页

作者： Maria Vittoria corazza Daniela D'Alessandro Paola Di Mascio Laura Moretti Department of Civil Building and Environmental EngineeringSapienza University of RomeRome 00185Italy

Home-to-school routes are very sensitive areas: they represent, for children, a learning tool for their everyday activities, but if poorly designed, maintained and equipped they can expose them to traffic risks. Sidewalks' inappropriate level of service and poor maintenance, especially, are main factors contributing to walking unsuitability, thus to poor comfort and safety levels for young pedestrians, and more in general for all the vulnerable non-motorized road users. This paper deals with a methodology specifically developed to highlight the quality of the urban environment where the home-to-school routes are located, according to four main criteria: wellbeing, usage, appearance, and safety and security. Each criterion is associated with a checklist including the most relevant features to assess, with a focus on maintenance as a key parameter to create safe and comfortable routes to school. An application, a case study in Rome, where the lack of regular maintenance results into a network of unsafe sidewalks, is also presented, analyzing three different areas where a number of schools are located. Detours when approaching school premises were surveyed, due to the levels of distresses and linked to the poor comfort and safety levels. As the mutual influence of built environment over road safety and maintenance requirements for home-to-school paths is not largely investigated thus far, the paper's goal is to provide advanced knowledge for studies and applications further afield.

关键词： Traffic engineering Road safety Pedestrians Home-to-school routes Sidewalks

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Managing sidewalk pavement maintenance:A case study to increase pedestrian safety

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Journal of Traffic and Transportation Engineering(English Edition) 2016年第3期3卷 203-214页

作者： Maria Vittoria corazza Paola Di Mascio Laura Moretti Department of Civil Building and Environmental EngineeringSapienza University of Rome

Comfort is a major requirement in planning pedestrian facilities. Pedestrians walk where they feel comfortable and when they do not feel at ease, they walk elsewhere. A typical example is that filthy, distressed, or too narrow sidewalks induce pedestrians to walk on carriageways. This behaviour jeopardizes road safety and highly dangerous to most users, leave them vulnerable. Unsuitable pavements can be the result of irregular maintenance operations to restore evenness after shock damage, weather phenomena, installation of equipment （e.g., posts, fences, urban furniture） with a reduction of walkable surface, or substandard repair work on pavements and patches due to emergency operations. These problems can be solved with an appropriate maintenance management system, which optimizes financial resources to make smart decisions about how to intervene with an adequate and lasting maintenance operation. This paper defines an evaluation index for sidewalk conditions as a part of an efficient set-up of a Sidewalk Management System, which is similar to the better known Road Management System. The study relies on sur- veys, as well as the classification and analysis of sidewalk distresses. The authors adapted an index already standardized by ASTM for roads and airports： the Pavement Condition Index （PCI）. PCI has been modified to consider the specific types on the sidewalks studied within this paper. To validate the method, a case study of a residential district in Rome, Italy, was carried out. The chosen area lacks regular maintenance and has therefore resulted in a network of unsafe sidewalks. Frequent detour routes were surveyed and related to the level of distresses within a general assessment of safety. This study con- centrates on sidewalks with flexible pavements because this type of pavement is the only one adopted in the survey areas and, in general, throughout Italy.

关键词： Sidewalks Maintenance Condition index Pedestrians Safety Asphalt pavements

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Safety ranking definition for infrastructures with high PTW flow

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Journal of Traffic and Transportation Engineering(English Edition) 2018年第5期5卷 406-416页

作者： Antonella Ragnoli Maria Vittoria corazza Paola Di Mascio Department of Civil Building and Environmental Engineering Sapienza University of Rome

Powered two-wheelers （PTWs） provide a suitable mode for a large portion of population in many cities due to rider＇s personal convenience and the vehicle supposed easiness of manoeuvring. At the same time PTWs present serious safety issues compared to other motorized vehicles. This paper reports the main outcome of study carried out in Rome, where this mode is very popular and assesses the economic efforts to make infrastructure safer for PTWs. The methodology, extensively described in the paper, includes three steps： the accident analysis, the development of economic indicators of accidents costs, the maintenance priority. In the first step the location of the PTWs local accidents are iden- tified, then the accidents are analyzed by means of the suitable indicators and, among these the safety potential （SAPO）. Lastly, according to the results of the analyzed indicators the need of infrastructure maintenance will be defined. Usually SAPO is applied to rural areas, but here it has been adapted to describe the phenomena of the urban area in hand. As a result, the estimation of the saving potential to improve the infrastructure safety levels, thus reducing the amount of accidents, is presented, along with recommendations on how to upscale the SAPO at city level.

关键词： Safety Accident costsl Powered two-wheeler (PTW) Maintenance

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Paradoxical relationship between proton pump inhibitors and COVID-19: A systematic review and meta-analysis

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World Journal of Clinical Cases 2021年第12期9卷 2763-2777页

作者： Maddalena Zippi Sirio Fiorino Roberta Budriesi Matteo Micucci Ivan corazza Roberta Pica Dario de Biase Claudio giuseppe gallo Wandong Hong Unit of gastroenterology and Digestive Endoscopy Sandro Pertini HospitalRome 00157Italy Unit of Internal Medicine Maggiore HospitalLocal Health Unit of BolognaBologna 40133Italy Food Chemistry and Nutraceuticals Laboratory Department of Pharmacy and Biotechnology(FaBiT)Alma Mater StudiorumUniversity of BolognaBologna 40133Italy Experimental Diagnostic and Speciality Medicine DepartmentUniversity of BolognaBologna 40138Italy Department of Pharmacy and Biotechnology University of BolognaBologna 40138Italy Internal Medicine Unit Budrio Hospital Azienda USLBologna 40138Italy Department of gastroenterology and Hepatology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina

BACKgROUND The proton pump inhibitors(PPIs),used to reduce gastric acid secretion,represent one of the most widely used pharmaceutical classes in the *** consumption as a risk factor for the evolution of severe forms of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection has been investigated as well as the mortality of these *** risks also appear to be linked to the duration and the *** the other hand,several studies have emerged with regard to the protective or therapeutic effects of these *** and more evidence underlines the immunomodulatory and anti-fibrotic role of *** addition,their ability to alkalize the contents of endosomes and lysosomes serves as an obstacle to the entry of the virus into the host *** To identify studies on the relationship between the intake of PPIs and coronavirus disease 2019(COVID-19)in patients affected by SARS-CoV-2 infection,with the main objective of evaluating the outcomes related to severity and *** A literature review was performed in November *** MEDLINE/PubMed,Cochrane Library,EMBASE and google Scholar databases were searched for all relevant articles published in English on this *** search terms were identified by means of controlled vocabularies,such as the National Library of Medicine’s MESH(Medical Subject Headings)and *** MESH terms and keywords used were as follows:“COVID-19”,“proton pump inhibitors”,“PPIs”,“SARS-CoV-2”,“outcomes”,“severity”and“mortality”.The inclusion criteria regarding the studies considered in our analysis were:meta-analysis,casecontrol,hospital-based case-control,population-based case-control,retrospective studies,online survey,as well as cohort-studies,while articles not published as full reports,such as conference abstracts,case reports and editorials were *** tried to summarize and pool all the data if *** A total of 9 studies were found that described the use of PPIs,of which only 5

关键词： COVID-19 Proton pump inhibitors SARS-CoV-2,Severity Mortality

Validation of the Italian translation of the perceived stigma scale and resilience assessment in inflammatory bowel disease patients

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World Journal of gastroenterology 2021年第39期27卷 6647-6658页

作者： Sara Cococcia Marco Vincenzo Lenti Caterina Mengoli Catherine Klersy Federica Borrelli de Andreis Matteo Secco Jihane ghorayeb Mariangela Delliponti gino Roberto corazza Antonio Di Sabatino First Department of Internal Medicine San Matteo Hospital FoundationUniversity of PaviaPavia 27100LombardiaItaly Service of Biometry&Statistics Foundation IRCCS Policlinico San MatteoPavia 27100LombardiaItaly Psychology Zayed UniversityDubai 00000United Arab Emirates

BACKgROUND Stigmatization is the separation of an individual from a group due to aspects that make them *** may in turn influence the perception of *** with inflammatory bowel disease(IBD)are susceptible to stigma,although data are very *** To validate an Italian translation of the IBD perceived stigma scale(PSS)in relation to patients’*** Consecutive IBD outpatients were prospectively enrolled(December 2018-September 2019)in an Italian,tertiary referral,IBD *** and demographic data were *** and resilience were evaluated through the IBD-PSS and the 25-item Connor-Davidson Resilience Scale,*** International Quality of Life Assessment Project approach was followed to translate the IBD-PSS into Italian and to establish data *** scores represent greater perceived stigma and *** analysis for factors associated with greater stigma was *** Overall,126 IBD patients(mean age 46.1±16.9)were *** International Quality of Life Assessment criteria for acceptable psychometric properties of the scale were satisfied,with optimal data *** was no ceiling effect,whilst floor effect was present(7.1%).The discriminant validity and the internal consistency reliability were good(Cronbach alpha=0.87).The overall internal consistency was 95%,and the test-retest reliability was excellent *** median PSS score was 0.45(0.20-0.85).Resilience negatively correlated with perceived stigma(Spearman’s correlation=-0.18,95%confidence intervals:-0.42-0.08,P=0.03).CONCLUSION We herein validated the Italian translation of the PSS scale,also demonstrating that resilience negatively impacts perceived stigma.

关键词： Crohn’s disease Quality of life Stress Ulcerative colitis

Is it worth investigating splenic function in patients with celiac disease?

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World Journal of gastroenterology 2013年第15期19卷 2313-2318页

作者： Antonio Di Sabatino Laura Brunetti gabriella Carnevale Maffè Paolo giuffrida gino Roberto corazza Department of Internal Medicine Celiac CentreS. Matteo Hospital FoundationUniversity of Pavia27100 PaviaItaly

Celiac disease, an immune-mediated enteropathy induced in genetically susceptible individuals by the ingestion of gluten, is the most frequent disorder associated with splenic hypofunction or atrophy. Defective splenic function affects more than one-third of adult patients with celiac disease, and it may predispose to a higher risk of infections by encapsulated bacteria and thromboembolic and autoimmune complications, particularly when celiac patients have concomitant pre-malignant and malignant complications (refractory celiac disease, ulcerative jejunoileitis and enteropathy-associated T-cell lymphoma). However, the clinical management of patients with celiac disease does not take into account the evaluation of splenic function, and in patients with high degree of hyposplenism or splenic atrophy the prophylactic immunization with specific vaccines against the polysaccharide antigens of encapsulated bacteria is not currently recommended. We critically re-evaluate clinical and diagnostic aspects of spleen dysfunction in celiac disease, and highlight new perspectives in the prophylactic management of infections in this condition.

关键词： Hyposplenism Memory B cell Pitted red cell Pneumococcal vaccine Splenic atrophy

肩袖钙化性肌腱病变:经皮超声引导下单针或双针法治疗的随机比较

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国际医学放射学杂志 2018年第1期 94-95页

作者： D.Orlandi g.Mauri F.Lacelli A.corazza C.Messina E.Silvestri 张俊峰 Department of Radiology Ospedale Evangelico Internazionale

摘要目的明确采用单针法或双针法是否会影响超声引导下经皮治疗肩袖钙化性肌腱病变病人的预后和疗效。材料与方法本前瞻性研究已获得病人知情同意和机构伦理委

关键词：超声引导下双针法单针法钙化性

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脾功能缺陷与肠病

国外医学(消化系疾病分册) 1984年第4期 223-225页

作者： corazza gR 朱舜时

脾功能减退(hyposplenism)一词系Eppinger于1913年提出,原指脾切除后状态,也可用以包括获得性脾萎缩引起的脾功能缺陷。长期以来,脾功能减退曾被认为无临床意义。由于若干病例发生暴发性感染,现已普遍认识到该病具有潜在致死性。许多肠... 详细信息

脾功能减退(hyposplenism)一词系Eppinger于1913年提出,原指脾切除后状态,也可用以包括获得性脾萎缩引起的脾功能缺陷。长期以来,脾功能减退曾被认为无临床意义。由于若干病例发生暴发性感染,现已普遍认识到该病具有潜在致死性。许多肠病可伴有脾功能减退,故了解其发生率、形成机制、免疫异常及预防措施具有重要意义。肠病时脾功能减退的发生率非脾切除引起的脾功能损害可见于下列肠病:乳糜泻、溃疡性结肠炎、克隆氏病、疱疹性皮炎、热带性口炎性腹泻、肠原性脂代谢障碍、慢

关键词：功能减退乳糜泻患者淋巴疾病溃疡性结肠脾功能肠疾病肠病