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Intrumer:A Multi Module Distributed Explainable IDS/IPS for Securing Cloud Environment

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Computers, Materials & Continua 2025年第1期82卷 579-607页

作者： Nazreen banu A S.K.b.Sangeetha Department of Computer Science and Engineering SRM Institute of Science and TechnologyVadapalani CampusChennai600026Tamil NaduIndia

The increasing use of cloud-based devices has reached the critical point of cybersecurity and unwanted network *** environments pose significant challenges in maintaining privacy and *** approaches,such as IDS,have been developed to tackle these ***,most conventional Intrusion Detection System(IDS)models struggle with unseen cyberattacks and complex high-dimensional *** fact,this paper introduces the idea of a novel distributed explainable and heterogeneous transformer-based intrusion detection system,named INTRUMER,which offers balanced accuracy,reliability,and security in cloud settings bymultiplemodulesworking together within *** traffic captured from cloud devices is first passed to the TC&TM module in which the Falcon Optimization Algorithm optimizes the feature selection process,and Naie bayes algorithm performs the classification of *** selected features are classified further and are forwarded to the Heterogeneous Attention Transformer(HAT)*** this module,the contextual interactions of the network traffic are taken into account to classify them as normal or malicious *** classified results are further analyzed by the Explainable Prevention Module(XPM)to ensure trustworthiness by providing interpretable *** the explanations fromthe classifier,emergency alarms are transmitted to nearby IDSmodules,servers,and underlying cloud devices for the enhancement of preventive *** experiments on benchmark IDS datasets CICIDS 2017,Honeypots,and NSL-KDD were conducted to demonstrate the efficiency of the INTRUMER model in detecting network trafficwith high accuracy for different *** outperforms state-of-the-art approaches,obtaining.b.tter performance metrics:98.7%accuracy,97.5%precision,96.3%recall,and 97.8%*** results validate the robustness and effectiveness of INTRUMER in securing diverse cloud environments against sophisticated cyber threats.

关键词： Cloud computing intrusion detection system transformers and explainable artificial intelligence(XAI)

Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João b.Relvas Institute of Research and Innovation in Health(i3S)and Institute for Molecular and Cell biology(IbMC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

Federated Learning’s Role in Next-gen TV Ad Optimization

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Computers, Materials & Continua 2025年第1期82卷 675-712页

作者： g.b.iela Dobrita Simona-Vasilica Oprea Adela bâra Department of Economic Informatics and Cybernetics Bucharest University of Economic StudiesBucharest010374Romania

In the rapidly evolving landscape of television advertising,optimizing ad schedules to maximize viewer engagement and revenue has become *** methods often operate in silos,limiting the potential insights gained from broader data analysis due to concerns over privacy and data *** article introduces a novel approach that leverages Federated Learning(FL)to enhance TV ad schedule optimization,combining the strengths of local optimization techniques with the power of global Machine Learning(ML)models to uncover actionable insights without compromising data *** combines linear programming for initial ads scheduling optimization with ML—specifically,a K-Nearest Neig.b.rs(KNN)model—for predicting ad spot *** into account the diversity and the difficulty of the ad-scheduling problem,we propose a prescriptivepredictive approach in which first the position of the ads is optimized(using google’s OR-Tools CP-SAT)and then the scheduled position of all ads will be the result of the optimization ***,this output becomes the target of a predictive task that predicts the position of new entries based on their characteristics ensuring the implementation of the scheduling at large scale(using KNN,Light gradient boosting Machine and Random Forest).Furthermore,we explore the integration of FL to enhance predictive accuracy and strategic insight across different broadcasting networks while preserving data *** FL approach resulted in 8750 ads being precisely matched to their optimal category placements,showcasing an alignment with the intended diversity ***,there was a minimal deviation observed,with 1133 ads positioned within a one-category variance from their ideal placement in the original dataset.

关键词： Ad scheduling prescriptive-predictive approach federated learning KNN

Energy Efficiency building Codes for Egypt

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Journal of Energy and Power Engineering 2011年第12期5卷 1134-1141页

作者： g.b. Hanna Housing and building National Research Center Cairo 12311 Egypt

This paper summarizes the results of energy simulation analysis to determine the effectiveness of building characteristics in reducing electrical energy consumption in residential buildings （conditioned and unconditioned） and commercial buildings （office ＆ hotel） in Egypt. Specifically, the impact on building envelope performance is investigated for different strategies such as window size, glazing type and building construction for two geographical locations in Egypt. This paper also studies the energy savings in residential and nonresidential buildings for different lighting power densities （LPD）, energy input ratios （EIR）, set point temperatures （SPT） and heating, ventilation, and air conditioning （I-WAC） systems. The study shows certain findings of practical significance, e.g. that a window-to-wall ratio of 0.20 and reasonably shaded windows lower the total annual electricity use for nonresidential buildings by more than 20% in the two Egyptian locations.

关键词： Energy codes simulation VDOE WWR LPD EPD SPT EIR.

building Energy Code for New Residential buildings in Egypt

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Journal of Environmental Science and Engineering 2011年第5期5卷 596-602页

作者： g.b. Hanna Housing and building National Research Center Cairo P. C. 11511 Egypt

This paper evaluates the potential of building envelope to save energy associated with the total electricity consumed. It summarizes the simulation analysis to determine the effectiveness of envelope construction in reducing total electrical consumption for residential buildings in Egypt. This paper studied the effect of the building envelope construction, orientation, window opening area as a ratio of wall area, and the glazing type for Cairo and Alexandria. It was determined that for most residential buildings in Egypt with SHgC values above 0.61, increases the total electrical consumption by 25%. Roof and wall insulation provides significant energy savings, 40% for the roofs and 12% for walls.

关键词： Energy code residential simulation insulation WWR SHgC PF.

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阿克巴大帝时代

On the pressure and stress singularities induced by steady flows of a pair of nonmiscible,incompressible,viscous fluids contacting a wall with slip

2017年

作者： (英)g. b.马勒森

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Acta Mechanica Sinica 2020年第3期36卷 686-691页

作者： g.b.Sinclair Department of Mechanical Engineering Louisiana State UniversityBaton RougeLA 70803USA

An earlier asymptotic analysis identified the flow-induced power and log singularities present when two nonmiscible,incompressible,viscous fluids contact a wall with no slip *** a parallel asymptotic analysis identifies such singularities in pressures and stresses when slip is *** the singularity exponents for the two types of contact conditions are similar,the angles of interface impingement that have either power or log singularities are usually quite distinct.

关键词： Incompressible viscous fluids Slip conditions Fluid-structure interactions Singular stresses

Deep learning identification of novel autophagic protein-protein interactions and experimental validation of beclin 2-Ubiquilin 1 axis in triple-negative breast cancer

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Oncology research 2025年第1期33卷 67-81页

作者： Xiang Li Wenke Jin Lifeng Wu Huan Wang Xin Xie Wei Huang.b.O Liu State Key Laboratory of Southwestern Chinese Medicine Resources School of Pharmacy and College of Medical Technology Chengdu University of Traditional Chinese Medicine Chengdu 611137 China. Department of biotherapy Cancer Center and State Key Laboratory of Biotherapy West China Hospital Sichuan University Chengdu 610041 China.

background:Triple-negative breast cancer (TNbC), characterized by its lack of traditional hormone receptors and HER2, presents a significant challenge in oncology due to its poor response to conventional therapies. Autophagy is an important process for maintaining cellular homeostasis, and there are currently autophagy biomarkers that play an effective role in the clinical treatment of tumors. In contrast to targeting protein activity, intervention with protein-protein interaction (PPI) can avoid unrelated crosstalk and regulate the autophagy process with minimal interference pathways.Methods:Here, we employed Naive bayes, Decision Tree, and k-Nearest Neig.b.rs to elucidate the complex PPI network associated with autophagy in TNbC, aiming to uncover novel therapeutic targets. Meanwhile, the candidate proteins interacting with beclin 2 were initially screened in MDA-Mb-231 cells using.b.clin 2 as bait protein by immunoprecipitation-mass spectrometry assay, and the interaction relationship was verified by molecular docking and CO-IP experiments after intersection. Colony formation, cellular immunofluorescence, cell scratch and 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) tests were used to predict the clinical therapeutic effects of manipulating candidate PPI.Results:by developing three PPI classification models and analyzing over 13,000 datasets, we identified 3733 previously unknown autophagy-related PPIs. Our network analysis revealed the central role of beclin 2 in autophagy regulation, uncovering its interactions with 39 newly identified proteins. Notably, the CO-IP studies identified the substantial interaction between beclin 2 and Ubiquilin 1, which was anticipated by our model and discovered in immunoprecipitation-mass spectrometry assay results. Subsequently, investigations showed that overexpressing.b.clin 2 increased Ubiquilin 1, promoted autophagy-dependent cell death, and inhibited proliferation and metastasis in MDA-Mb-231 cells.

关键词： Artificial intelligence (AI) Autophagy beclin 2 Protein-protein interactions (PPI) Triple-negative breast cancer (TNbC) Ubiquilin 1

Reduction Method for Reachability Analysis of Petri Nets

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Tsinghua Science and Technology 2003年第2期8卷 231-235页

作者： HAN Zandong(韩赞东) LEE g.b.(李基范) Department of Mechanical Engineering Tsinghua University Beijing 100084 China Research Institute of Industrial Science and Technology Pohang 790600 Korea

Reachability analysis is an important approach for acquiring Petri net (PN) properties. The reachability tree and the solution of the state equation are two commonly used methods for reachability analysis, but they can result in state explosion and spurious solutions in some cases. As a significant complementary method, the PN reduction technique simplifies the reachability analysis by reducing the net size while preserving the reachability. This paper introduces several useful reduction rules and defines a reduction process for the analysis of reachability which is easy to understand and implement. Some examples are given to explain the method to solve the reachability problem. The analysis shows that the proposed reduction method preserves the visualization feature of PN and can be easily used.

关键词： Petri net reachability analysis reduction rules net reduction