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Dietary fibre enrichment of supplemental feed modulates the development of the intestinal tract in suckling piglets

journal of Animal Science and Biotechnology 2020年第1期11卷 183-193页

作者： H.M.j.Van Hees M.Davids D.Maes S.Millet S.possemiers L.A.den Hartog T.A.T.g.van Kempen g.p.j.janssens Department of Nutrition Genetics and EthologyGhent UniversityMerelbekeBelgium Research and Development Trouw NutritionAmersfoortThe Netherlands Department of Internal and Vascular Medicine Amsterdam University Medical CentreAmsterdamThe Netherlands Department of Reproduction Obstetrics and Herd HealthGhent UniversityMerelbekeBelgium ILVO Eenheid DierMelleBelgium BioActor MaastrichtThe Netherlands Animal Nutrition Wageningen University and ResearchWageningenThe Netherlands North Carolina State University RaleighNCUSA.

Background:Commercial pre-weaning diets are formulated to be highly digestible and nutrient-dense and contain low levels of dietary *** contrast,pigs in a natural setting are manipulating fibre-rich plant material from a young ***,dietary fibre affects gastrointestinal tract(gIT)development and health in older *** hypothesised that supplemental diets that contain vegetal fibres are accelerating gIT development in suckling piglets in terms of size and *** d 2 of life,sow-suckled piglets had access to a low fibre diet(CON),a diet with a fermentable long-chain arabinoxylan(lc-AXOS),a diet with a largely non-fermentable purified cellulose(CELL),or a diet containing both *** the initial 2 weeks,the control diet was a high-density milk replacer,followed by a dry and highly digestible creep *** weaning at 25 d,15 piglets from each treatment group,identified as eaters and originating from six or seven litters,were sacrificed for post-mortem examination of gIT morphology,small intestinal permeability and metabolic profile of the *** microbiota composition of the mid-colon was evaluated in a sub-set of ten ***:No major statistical interactions between the fibre sources were *** consumed the fibrecontaining milk supplements and creep diets *** size and small intestinal permeability was not *** intestinal fill was increased with lc-AXOS only,while relative large intestinal weight was increased with both fibre sources(ppH and tended to increase ileal DM content compared to CON(ppppropionate(pposition showed a high individual variation and limited dietary ***,CELL induced minor shifts in specific genera,with notable reductions of Escherichia-Sh

关键词： Dietary fibre gut maturation gut microbiota Suckling piglets

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家鸽的营养

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国外畜牧学（猪与禽） 2003年第6期23卷 12-17页

作者：李强康相涛覃矜 j.Sales g.p.j.janssens 比利时ghent大学兽医学院动物营养、遗传、育种和生态系

尽管人们从公元前2500年起就将鸽子用于产肉、观赏、运动及用作实验动物,但关于鸽子的营养需要和饲喂方面的信息却知之甚少。部分原因在于雏鸽由亲鸽喂养至28天时即达到成熟体重。与其它家禽相比,雏鸽的生长速度(0.1466～0.1945克/天)... 详细信息

尽管人们从公元前2500年起就将鸽子用于产肉、观赏、运动及用作实验动物,但关于鸽子的营养需要和饲喂方面的信息却知之甚少。部分原因在于雏鸽由亲鸽喂养至28天时即达到成熟体重。与其它家禽相比,雏鸽的生长速度(0.1466～0.1945克/天)远高于鸡(0.0450克/天)和鹌鹑(0.077～0.097克/天)。这种快速生长是由双亲分泌的鸽乳引起的,鸽乳的形成由催乳素的分泌而引起,而受亲鸽的抱窝而触发。鸽乳的构成主要包括蛋白质(11.0～18.8％)和脂肪(4.5～12.7％),明显缺乏碳水化合物。此外,成年鸽主要饲喂各种谷物原粮。由于鸽子本身固有的采食特性,无法根据其它禽类的营养需要来确定其营养需要量。根据成年鸽的繁殖性能,日粮粗蛋白含量推荐值为12％～18％,代谢能推荐值在12兆焦/千克左右。一些谷物的氮校正表观代谢能值,比如玉米(14.76兆焦/千克)、大麦(12.36兆焦/千克)、高梁(13.87兆焦/千克)、豌豆(14.01兆焦/千克)等的氮校正表观代谢能值与用家禽测得的表观代谢能值并没有很大的差别。对于鸽子来说,能够更好地利用脂肪作为能量来源(与其利用碳水化合物作为能量源的能力相比)。还讨论了饲料添加剂的应用并对进一步的研究提出了建议。

关键词：家鸽营养水平消化系统饲喂方法

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Does feeding more phases reduce ammonia concentrations from broiler litter?

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Animal Nutrition 2022年第4期11卷 152-159页

作者： Madri Brink geert p.j.janssens Evelyne Delezie Flanders Research Institute for Agriculture Fisheries and Food(ILVO)Animal Sciences UnitScheldeweg 689090 MelleBelgium Department of Veterinary and Biosciences Ghent UniversityHeidestraat 199820 MerelbekeBelgium

We compared a 3-and 5-phase feeding program in terms of ammonia concentrations measured at litter level,litter composition and quality,nitrogen(N)utilization,performance,welfare,and meat deposition in broilers.A total of 744 Ross 308 male broilers was divided into 2 treatments,each with 6 *** 3-phase diets were formulated to Cp and digestible lysine contents of 205 and 11.5 g/kg(0 to 9 d),195 and 10.8 g/kg(9 to 24 d),and 183.3 and 10.15 g/kg(24 to 39 d),*** 5-phase diets had additional phases from 17 to 24 d and 32 to 39 d with Cp and digestible lysine contents of 188 and 10.4 g/kg and 177 and 9.8 g/kg,*** 5 phases reduced the NH3concentrations at litter level by37.95%and 20.81%at 23(pge(pgen concentration for the 5-phase treatment than the 3-phase treatment at 24 and 39 d of age(pphase treatment at 39 d of age(pge litter pH at 24 and 32 d of age(pphase treatments had a lower incidence of foot lesions at 24 d of age(pperformance as well as carcass yield could be maintained,except for FCR,which was higher for the 5-phase treatment between 17 and 24 d of age and the overall period(ppectively).The impact of the 5-phase treatment regarding the utilization of N(digestibility,excretion,and retention)was less clear,however the NH3volatilized from the litter was significantly *** 5 phases may therefore potentially reduce the NH3emitted from broiler houses which has several environmental and health *** the 5-phase treatment resulted in a significant decrease in feed efficiency,growth performance and meat deposition were maintained.

关键词： Broiler Ammonia phase feeding Crude protein performance

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Reduction of dietary crude protein and feed form:Impact on broiler litter quality,ammonia concentrations,excreta composition,performance,welfare,and meat quality

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Animal Nutrition 2022年第2期9卷 291-303页

作者： Madri Brink geert p.j.janssens peter Demeyer Ozer Bagci Evelyne Delezie Flanders Research Institute for Agriculture Fisheries and Food(ILVO)Animal Sciences UnitScheldeweg 689090 MelleBelgium Department of Nutrition Genetics and EthologyGhent UniversityHeidestraat 199820 MerelbekeBelgium Flanders Research Institute for Agriculture Fisheries and Food(ILVO)Agricultural Engineering UnitBurg.Van Gansberghelaan 1159820 MerelbekeBelgium Department of Mechanical Engineering Eindhoven University of Technology5600 MB-EindhovenNetherlands.

Nitrogen(N)excreted by poultry is converted to ammonia(NH3),presenting an environmental risk and a health risk to the farmer and animals.A study was performed to investigate the effect of reduced Cp and feed form on broiler performance and welfare,meat and litter quality,N utilization,and NH3 concentrations at litter level.A total of 2,232 Ross 308 male broilers was divided into 6 treatments and 6 replicates,which was fed diets in both pellet and mash forms with different Cp levels of 205.0 g/kg(H,high),187.5 g/kg(M,intermediate)and 175.0 g/kg(L,low)in the grower phase and 195.0 g/kg(H),180.0 g/kg(M)and 165.6 g/kg(L)in the finisher *** amino acids(AA)were supplemented to maintain digestible AA-to-digestible lysine *** dietary Cp content to 187.5 g/kg in the grower phase and 180.0 g/kg in the finisher phase reduced NH3 concentrations at litter level(pp had no additional *** treatments had better litter qualities and lower incidences of foot and hock lesions than pellet treatments at d 38(pp had lower incidence of foot lesions at d 38(ppelleted diets had higher ADFI,ADg,and final BW,improved feed conversion ratio(FCR),and heavier carcasses(pproduction period of 39 *** could not be maintained when birds were fed L Cp pelleted *** study demonstrated that,with the supplementation of AA to meet requirements,the concentration of dietary Cp can be reduced to 187.5 and 180.0 g/kg in the grower and finisher phases respectively,without impairing broiler performance,meat yield and *** diets were favorable when considering the overall litter quality and welfare of the ***,they could not maintain the same broiler performance and slaughter yield as pelleted *** from the present study may assist the poultry sector towards a socially acceptable lowemission

关键词： Broiler Ammonia Crude protein Feed form performance

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Effect of dietary fibre on the gastrointestinal microbiota during critical illness:A scoping review

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World journal of Critical Care Medicine 2025年第1期14卷 49-59页

作者： Angajendra N ghosh Calum j Walsh Matthew j Maiden Tim p Stinear Adam M Deane Department of Intensive Care The Northern HospitalEpping 3076VictoriaAustralia Department of Microbiology and Immunology The Peter Doherty Institute for Infection and ImmunityMelbourne 3052VictoriaAustralia Department of Intensive Care The Royal Melbourne HospitalThe University of MelbourneParkville 3050VictoriaAustralia Department of Intensive Care Medicine The Royal Melbourne HospitalParkville 3050VictoriaAustralia

The systemic effects of gastrointestinal(gI)microbiota in health and during chronic diseases is increasingly *** strategies to modulate the gI microbiota during chronic diseases have demonstrated *** changes in dietary intake can rapidly change the gI microbiota,the impact of dietary changes during acute critical illness on the microbiota remain *** fibre is metabolised by carbohydrate-active enzymes and,in health,can alter gI *** aim of this scoping review was to describe the effects of dietary fibre supplementation in health and disease states,specifically during critical *** controlled trials and prospective cohort studies that include adults(>18 years age)and reported changes to gI microbiota as one of the study outcomes using non-culture methods,were *** show dietary fibres have an impact on faecal microbiota in health and *** fibre,inulin,has a marked and specific effect on increasing the abundance of faecal *** chain fatty acids produced by Bifidobacteria have been shown to be beneficial in other patient *** few trials have evaluated the effect of dietary fibre on the gI microbiota during critical *** research is necessary to establish optimal fibre type,doses,duration of intervention in critical illness.

关键词： gastrointestinal microbiota Dietary fibre Health Critical illness Short chain fatty acids

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Reproduction,Development,and growth Response to Captive Diets in the Shangcheng Stout Salamander,pachyhynobius shangchengensis(Amphibia,Urodela,Hynobiidae)

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Asian Herpetological Research 2012年第3期3卷 192-197页

作者： Frank pASMANS geert p.j.janssens Max SpARREBOOM3 jianping jIANg Kanto NISHIKAWA Department of pathology Bacteriology and Avian DiseasesFaculty of Veterinary MedicineGhent University Salisburylaan 1339820 MerelbekeBelgium Animal Nutrition Laboratory Faculty of Veterinary MedicineGhent University Salisburylaan 1339820 MerelbekeBelgium Netherlands Centre for Biodiversity Naturalis p.O.Box 9517 NL-2300 RA LeidenThe Netherlands Chengdu Institute of Biology Chinese Academy of Sciences graduate School of Human and Environmental Studies Kyoto UniversityYoshida-nihonmatsu-cho Sakyo606-8501 KyotoJapan

The Shangcheng stout salamander(pachyhynobius shangchengensis) is a poorly known stream dwelling hynobiid salamander from China. We studied the reproduction, development and growth response of the salamander to different diets in captivity. Two females each produced two unique, striated egg sacs, with each containing 18 and 20, and 22 and 32 white eggs with an average diameter of 3.3 mm. Hatchlings(n = 27) had front- and hind-limb buds with interdigit membranes and a large yolk sac, and developed cornified finger and toe tips during further development. Metamorphosis occurred between d 441 and d 454 after hatching at an average total length of 94.8 mm(n = 21). These reproductive and developmental traits fit in well with the ancestral state reconstruction in hynobiids. If corrected for dry mass, feed conversion ratios obtained by feeding bloodworms(Chironomidae) to p. shangchengensis larvae and mealworms(Tenebrio molitor) to postmetamorphs, were very low(0.33 and 0.34 respectively), equaling a very high mass conversion efficiency.

关键词： pachyhynobius shangchengensis husbandry reproduction nutrition development

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Supplementing oat hulls to the diet of suckling piglets altered their intestinal tract and colonic microbiota development

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Animal Nutrition 2023年第1期12卷 284-296页

作者： Hubèrt M.j.van Hees Koen Chiers Leo A.den Hartog Theo A.T.g.van Kempen Dominiek Maes Sam Millet geert p.j.janssens Department of Veterinary and Biosciences Ghent UniversityMerelbekeBelgium Trouw Nutrition Research and Development Amersfoortthe Netherlands Department of pathology Ghent UniversityMerelbekeBelgium Animal Nutrition Wageningen University and ResearchWageningenthe Netherlands Department of Animal Science North Carolina State UniversityRaleighNCUSA Department of Reproduction Obstetrics and Herd HealthGhent UniversityMerelbekeBelgium ILVO(Flanders Research Institute for Agriculture Fisheries and Food)MelleBelgium

Current study evaluated the effect of a fine and coarsely ground insoluble dietary fibre source on the gastrointestinal development of suckling *** hulls(OH)were selected as a model feedstuff,rich in cellulose,lignin,and insoluble dietary *** experimental supplemental diets were formulated:a finely ground,low fibre and nutrient dense diet served as control(CON).For the 2 high fibre diets,15%heat-treated starch in CON was exchanged with OH,either finely(OH-f)or coarsely ground(OH-c).Litters of 10 primi-and multiparous sows(mean litter size 14.6±0.84)were *** a litter,experimental diets were allotted to triplets of 4 *** approximately 12 d of age,piglets’individual feed intakes were recorded 2 times per day when separated from their dam for 70 *** could suckle with their dam for the remainder of the *** d 24 and 25,from the total pool of 120 piglets,seven healthy well-eating piglets per treatment were selected for post-mortem evaluation,resulting in 14 replicates per *** of OH-c and OH-f did not impede clinical health and production performance of *** full stomach weights tended to be greater for OH-c compared to OH-f whereas CON was intermediate(p=0.083).Supplementing OH significantly increased ileal villus height and caecal dry matter concentration(pgth,contents weight,short-chain fatty acid concentration and reduced total bacterial count as well asγ-proteobacteria count and proportion(ppecifically increased full gastrointestinal tract weight and caecum contents weight compared to piglets fed CON and ***,OH-c reduced colonic crypt depth when compared to OH-f(p=0.018).In conclusion,supplementing OH to a diet for suckling piglets exerted subtle developmental effects on gastrointestinal morphology and colonic microbial *** effects were largely independent from the particle size of the OH.

关键词： Oat hull Insoluble fibre gastrointestinal development Suckling piglet

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Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report

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Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： pascal j.goldschmidt-Clermont Aisha Khan george jimsheleishvili patricia graham Adriana Brooks Risset Silvera Alexander j.p.goldschmidt Damien D.pearse W.Dalton Dietrich Allan D.Levi james D.guest Miller School of Medicine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami project to Cure paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzady International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and function of motor neurons,axonal networks,and the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and potential trophic activities of Schwann cell-derived exosomal vesicles have been *** case report describes the treatment of a patient with advanced amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles,marking,to our knowledge,the first instance of such *** 81-year-old male patient presented with a 1.5-year history of rapidly progressive amyotrophic lateral *** initial diagnosis,the patient underwent a combination of generic riluzole,sodium phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and *** patient volunteered to participate in an FDA-approved single-patient expanded access treatment and received weekly intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles to potentially restore impaired Schwann cell and motor neuron *** confirmed that cultured Schwann cells obtained from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared impaired(senescent)and that exposure of the patient’s Schwann cells to allogeneic Schwann cell-derived exosomal vesicles,cultured expanded from a cadaver donor improved their growth capacity in *** a period of observation lasting 10 weeks,during which amyotrophic lateral sclerosis Functional Rating Scale-Revised and pulmonary function were regularly monitored,the patient received weekly consecutive infusions of 1.54×1012(×2),and then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-derived exosomal vesicles diluted in 40 mL of Dulbecco’s phosphate-buffered *** of the infusions were associated with adverse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

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Feasibility of upgrading the energy performance of recent massive brick houses

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Frontiers of Architectural Research 2014年第1期3卷 44-54页

作者： Bart janssens Aviel Verbruggen Department of Design Sciences and Architecture University of Antwerp Mutsaardstraat 3 I Antwerp2000 Belgium Department of Environment Technology end Technology Munugement University of Antwerp Prinsstraut13 Antwerp 2000 Belgium

Climate change policies imply significant reductions of energy use in buildings. For this, prevailing energy performance standards fall short, notwithstanding the emergence of stricter national building regulations. Regulations cover new built and renovation projects. New built houses that miss the best energy performance are soon candidate for energy upgrading. We investigate the architectural and economic aspects of upgrading recently built detached massive brick houses in Flanders （Belgium）. For representing actual building practices, consecutive upgrading steps from ｜ower to higher energy performance levels are considered. Questions addressed are： What is technically feasible in upgrading such houses？ Which construction works are easy, which difficult？ What are the architectural and financial consequences of a thorough upgrading？ The analysis shows that deep energy transformations are financially unacceptable, related to the irrevocab｜e character of investments in energy efficiency attributes of massive brick houses. This confirms that energy performance endowment measures should be designed and implemented at the time of first construction of a building.

关键词： Massive brick houses Upgrading energyperformance Thorough retrofits

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Development and Electrochemical Studies of Ruthenium Based Mixed Oxide Catalyst Electrodes for Chlorine Evolution

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Chemical Research in Chinese Universities 2002年第2期18卷 133-138页

作者： L.X.Yang j.p.g.Farr Department of Chemical and processing Engineering University of Newcastle Merz CourtNewcastle upon Tyne NE17RU School of Metallurgy and Materials The University of Birmingham EdgbastonBirmingham B152TTUK

Experimental results are presented which allow comparison of the electrochemical performance of RuO 2/Ti, Ru 0 3 Sn 0 7 O 2/Ti and Ru 0 3 V 0 7 O 2/Ti catalysts prepared on a titanium substrate by thermal decomposition from respective precursors. The highest activity for chlorine evolution is observed on the Ru 0 3 V 0 7 O 2/Ti electrode, lower on Ru 0 3 Sn 0 7 O 2/Ti and least on RuO 2/Ti. Voltammograms obtained in the polarisable region are used to characterize the different electrodes. Further more an analysis of the catalytic activity and reaction kinetics of the developed electrodes in NaCl are presented.

关键词： Catalyst Cl_(2) evolution Ruthenium oxide

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