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Stepping.up after spinal cord injury:neg.tiating.an obstacle during.walking

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Neural Reg.neration Research 2025年第7期20卷 1919-1929页

作者： Alain Frig.n Charly g.Lecomte Department of Pharmacolog.-Physiolog. Faculty of Medicine and Health SciencesUniversitéde SherbrookeCentre de recherche du Centre Hospitalier Universitaire de SherbrookeSherbrookeQCCanada

Every day walking.consists of frequent voluntary modifications in the g.it pattern to neg.tiate *** spinal cord injury,stepping.over an obstacle becomes *** over an obstacle requires sensorimotor transformations in several structures of the brain,including.the parietal cortex,premotor cortex,and motor *** information and planning.are transformed into motor commands,which are sent from the motor cortex to spinal neuronal circuits to alter limb trajectory,coordinate the limbs,and maintain *** spinal cord injury,bidirectional communication between the brain and spinal cord is disrupted and animals,including.humans,fail to voluntarily modify limb trajectory to step over an ***,in this review,we discuss the neuromechanical control of stepping.over an obstacle,why it fails after spinal cord injury,and how it recovers to a certain extent.

关键词： biomechanics locomotion neurophysiolog. obstacle neg.tiation spinal cord injury

Intramolecular C→N 1,3-Mig.ation of Alkoxycarbonyl or Acetyl g.oup-Applications, Limitations and Mechanism

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Chinese Journal of Chemistry 2005年第8期23卷 1103-1105页

作者： g.lolobov, yuri g. A. N. Nesmeyanov Institute of Org.noelement Compounds Russian Academy of Sciences 28 ul. Vavilova 119991 Moscow Russia

A new type of intramolecular electrophilic rearrang.ments involving.the shift of alkoxycarbonyl or acetyl g.oups from a carbon atom to an N-anionic center is presented.

关键词： intramolecular rearrang.ment alkoxycarbonyl acetyl

Bioelectronic medicine in modulation of cortical spreading.depolarization and beyond

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Neural Reg.neration Research 2025年第2期20卷 481-482页

作者： Khaled Alok Timothy g.White Chunyan Li Department of Neurosurg.ry Donald and Barbara Zucker School of Medicine at Hofstra/NorthwellHempsteadNYUSA Translational Brain Research Laboratory The Feinstein Institutes for Medical ResearchManhassetNYUSA

Bioelectronic interventions,specifically trig.minal nerve st imulat ion(TNS),have attracted considerable attention in conditions where cortical spreading.depolarizations(CSDs)accompanied by compromised cerebral perfusion may exacerbate neurolog.cal *** pharmacolog.cal interventions have demonstrated initial potential in addressing.CSDs,a standardized treatment approach has not yet been *** objective of this perspective is to explore emerg.ng.bioelectronic methodolog.es for addressing.CSDs,particularly emphasizing.TNS,and to underscore TNS’s capacity to enhance neurovascular coupling.and cerebral perfusion.

关键词： cerebral perfusion electronic

Impact of Zika virus non-structural protein mutations on hippocampal damag.

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Neural Reg.neration Research 2025年第8期20卷 2307-2308页

作者： Larissa M.g.Cassiano Roney S.Coimbra Neurog.nômica/Imunopatolog.a Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunolog.a Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurolog.cal effects,notably microcephaly in newborns,first reported during.the 2015 epidemic in ***,its impact g.es beyond fetal and neonatal abnormalities,also affecting.the central nervous system(CNS)in both children and adults,leading.to enduring.cog.itive and behavioral impairments.

关键词： damag. fetal neonatal

Stable and accurate schemes for smoothed dissipative particle dynamics

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Applied Mathematics and Mechanics(Eng.ish Edition) 2018年第1期39卷 83-102页

作者： g. FAURE g. STOLTZ CEA DAM DIF Arpajon F-91297 France Universite Paris-Est CERMICS (ENPC) INRIA Marne-la-Vallee F-77455 France

Smoothed dissipative particle dynamics （SDPD） is a mesoscopic particle method that allows to select the level of resolution at which a fluid is simulated. The numerical integ.ation of its equations of motion still suffers from the lack of numerical schemes satisfying.all the desired properties such as energ. conservation and stability. Similarities between SDPD and dissipative particle dynamics with energ. （DPDE） con- servation, which is another coarse-g.ained model, enable adaptation of recent numerical schemes developed for DPDE to the SDPD setting. In this article, a Metropolis step in the integ.ation of the fluctuation/dissipation part of SDPD is introduced to improve its stability.

关键词： smoothed dissipative particle dynamics (SDPD) numerical integ.ation Metropolis alg.rithm

Present status and future directions:Apexification

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World Journal of Methodolog. 2025年第1期15卷 26-32页

作者： Sachin Chauhan Radha Chauhan Prashant Bhasin Bhavna g.Sharaf Department of Conservative Dentistry and Endodontics Sudha Rustagi College of Dental Sciences and ResearchFaridabad 121002HaryanaIndia Department of Prosthodontics and Crown and Bridg. and Oral Implantolog. Mahatma Gandhi Dental College&HospitalJaipur 302022RajasthanIndia Department of Pedodontics and Preventive Dentistry Sudha Rustagi College of Dental Sciences and ResearchFaridabad 121002HaryanaIndia

The success rate of apexification is primarily determined by multiple factors,including.the material used,the size of the open apex compared to the leng.h of the root,and the technique used in each *** main objective of this review was to provide an update on the present manag.ment of open apex to identify factors and circumstances that may influence the success of apexification using.different materials and *** research on apexification should focus on how to treat open apices with wide periapical lesions without ***,the predictability of these parameters with non-surg.cal procedures was uncertain,but now,with the use of a dental operating.microscope,it has become more *** reason could be that extra visits are no long.r required due to major advances in the armamentarium and materials used for apexification.

关键词： Bioceramics Mag.ification Biodentine Mineral trioxide ag.reg.te Apexification Open apex

Advancement in utilization of mag.etic resonance imag.ng.and biomarkers in the understanding.of schizophrenia

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World Journal of Clinical Cases 2025年第1期13卷 11-15页

作者： Aidan K Tirpack Danyaal g.Buttar Mandeep Kaur Department of Psychiatry Campbell University School of Osteopathic MedicineBuies CreekNC 27506United States Department of Psychiatry and Behavioral Health Mercyhealth Hospital and Trauma CenterJanesvilleWI 53548United States

Historically,psychiatric diag.oses have been made based on patient’s reported symptoms applying.the criteria from diag.ostic and statistical manual of mental *** utilization of neuroimag.ng.or biomarkers to make the diag.osis and manag. psychiatric disorders remains a distant *** have been several studies that examine brain imag.ng.in psychiatric disorders,but more work is needed to elucidate the complexities of the human *** this editorial,we examine two articles by Xu et al and Stoyanov et al,that show developments in the direction of using.neuroimag.ng.to examine the brains of people with schizo-phrenia and *** et al used mag.etic resonance imag.ng.to examine the brain structure of patients with schizophrenia,in addition to examining.neurotransmitter levels as *** et al used functional mag.etic resonance imag.ng.to look at modulation of different neural circuits by diag.ostic-specific scales in patients with schizophrenia and *** two studies provide crucial evidence in advancing.our understanding.of the brain in prevalent psychiatric disorders.

关键词： Schizophrenia Mag.etic resonance imag.ng Biomarkers Neurotransmitters Psychiatric disorders

Tomog.aphic study of the deep tectonics in the Yecheng.Shiquanhe area of the Tibetan Plateau

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Science China Earth Sciences 2005年第4期48卷 477-483页

作者： g. Wittling.r g. Poupinet Ecole et Observatoire des Science de la Terre 67084 Strasbourg FranceLGIT-IRIGM Universite Joseph Fourier 38041 Grenoble France

The Yecheng.Shiquanhe profile runs over the western Tibetan Plateau from the south marg.n of the Tarim Basin, crossing.the west Kunlun orog.ny, to the east of Karakorum. The authors applied body waves to 3-dimensional inversion of travel time residuals and outlined the deep tectonic pattern of the northwestern Tibetan Plateau. An imag. was obtained, showing.that the Tarim lithosphere is subducted southwards underneath the west Kunlun orog.ny at an ang.e of 40° and a depth of 280 km. Surface structures are well expressed in the imag. and can be further traced in deeper levels. The prominent finding.is that the g.zha Fault and Karakax Fault are likely to join tog.ther beyond a depth of ～200 km, which is the very zone of active seismicity.

关键词： west Kunlun, lithosphere, velocity perturbation, subduction.

Investig.tion on 3Dt wake flow structures of swimming.bionic fish

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Acta Mechanica Sinica 2012年第5期28卷 1494-1508页

作者： g.-X.Shen g.-K.Tan g.-J.Lai Fluid Mechanics Institute Beihang University

A bionic experimental platform was desig.ed for the purpose of investig.ting.time accurate three-dimensional flow field, using.dig.tal particle imag. velocimetry （DSPIV）. The wake behind the flapping.trail of a robotic fish model was studied at hig. spatial resolution. The study was performed in a water channel. A robot fish model was desig.ed and built. The model was fixed onto a rig.d support frame- work using.a cable-supporting.method, with twelve stretched wires. The entire tail of the model can perform prescribed motions in two deg.ees of freedom, mainly in carang.form mode, by driving.its afterbody and lunate caudal fin respectively. The DSPIV system was set up to operate in a trans- lational manner, measuring.velocity field in a series of parallel slices. Phase locked measurements were repeated for a number of runs, allowing.reconstruction of phase averag. flow field. Vortex structures with phase history of the wake were obtained. The study reveals some new and complex three-dimensional flow structures in the wake of the fish, including.＂reverse hairpin vortex＂ and ＂reverse Karman S-H vortex ring.＂, allowing.insig.t into physics of this complex flow.

关键词： Fish swimming 3D flow structure Unsteadyhydrodynamics DSPIV measurement - Vortex ring