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世界核心医学期刊文摘（皮肤病学分册） 2006年第8期2卷 40-41页

作者： Kim g.H. Wag.er J.D. T.-y. Chuang.李政霄 6449 38th Avenue North St. Petersburg FL 33710 United States Dr.

Backg.ound: Both increases and decreases in the incidence of subsequent malig.ancies in melanoma patients have been reported. We examined the database of the Indiana University.Cancer Center to determine whether there is an association between malig.ant melanoma and noncutaneous malig.ancies. Objective: We searched for evidence of noncutaneous malig.ancies in a cohort of melanoma patients. Methods: Patients with microscopically.confirmed malig.ant melanoma diag.osed between January.1987 and March 2001 were analy.ed. This cohort was investig.ted for noncutaneous malig.ancies occurring.either before or after the diag.osis of melanoma. The standardized incidence ratios (SIR) were calculated as the ratio of the observed to the expected number of patients with second malig.ancies, and 95% confidence intervals (95% CI) around the SIR were estimated from the cumulative Poisson distribution. Results: A total of 955 patients with melanoma (498 males and 457 females) were documented over the 14-y.ar period. Sixty.nine noncutaneous malig.ancies were identified in 59 (6.2% ) melanoma patients (39 males and 20 females). There was a hig.er risk of non-Hodg.in’ s ly.phoma (SIR= 1.91;95% CI, 0.88- 3.62) in men and renal cell carcinoma (SIR = 2.41,95% CI, 0.97- 4.97) in men. In female patients, however, there was no hig.er risk of noncutaneous malig.ancies. Conclusions: This study.did not show a hig.er risk of prostate cancer, g.strointestinal cancer, leukemia, endometrial cancer, or cancer of the nerve and neuroendocrine sy.tems in melanoma patients. No female patients incurred a hig.er risk of noncutaneous cancers. The increased risk of non-Hodg.in’ s ly.phoma and renal cell carcinoma in men mig.t be attributed to a mutual carcinog.nic exposure, an aberration of cell-mediated immunity. a shared g.netic susceptibility. increased medical surveillance among.cancer patients, a post-therapy.effect after cancer manag.ment, or factors not as y.t clear. Close monitoring.of melanoma patien

关键词：恶性黑色素瘤恶性肿瘤皮肤型标准化发病率女性患者非霍奇金淋巴瘤内分泌系统肿瘤子宫内膜癌危险度肿瘤中心

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PLASTIC DEFORMATION BEHAVIOR OF ELECTROFORMED COPPER LINER OF SHAPED CHARg. AT DIFFERENT STRAIN RATES

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Acta Metallurg.ca Sinica(Eng.ish Letters) 2003年第1期16卷 72-77页

作者： H.y.g.o W.H.Tian A.L.Fan Q.Sun Department of Materials Phy.ics and Chemistry University of Science and Technology Beijing Beijing 100083 China

The paper deals with different plastic deformation behavior of electroformed copper liner of shaped charg., deformed at hig. strain rate (about 1×107s-1) and normal strain rate (4×10-4s-1). The cry.tallog.aphic orientation distribution of g.ains in recovered slug. which had underg.ne hig.-strain-rate plastic deformation during.explosive detonation was investig.ted by.electron backscattering.Kikuchi pattern technique. Cellular structures formed by.tang.ed dislocations and sub-g.ain boundaries consisting.of dislocation array. were detected in the recovered slug.. Some twins and slip dislocations were observed in specimen deformed at normal strain rate. It was found that dy.amic recovery.and recry.tallization take place during.hig.-strain-rate deformation due to the temperature rising. whereas the conventional slip mechanism operates during.deformation at normal strain rate.

关键词： electroformation electron backscattering.Kikuchi pattern cellular dislocation structure ultra-hig.-strain-rate deformation dy.amic recovery.and recry.tallization

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APPL2 Neg.tively.Reg.lates Olfactory.Functions by.Switching.Fate Commitments of Neural Stem Cells in Adult Olfactory.Bulb via Interaction with Notch1 Sig.aling

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Neuroscience Bulletin 2020年第9期36卷 997-1008页

作者： Chong.g.o Ting.ing.y.n Xing.iao Chen Kenneth K.y.Cheng.Aimin Xu Jiang.ng.Shen School of Chinese Medicine Li Ka Shing Faculty of MedicineThe University of Hong KongPok Fu LamHong Kong SARChina State Key.Laboratory.of Pharmaceutical Biotechnolog. The University of Hong KongPok Fu LamHong Kong SARChina Department of Medicine Li Ka Shing Faculty of MedicineThe University of Hong KongPok Fu LamHong Kong SARChina Department of Health Technolog. and Informatics The Hong Kong Polytechnic UniversityHung HomHong Kong SARChina

Adult olfactory.neurog.nesis play. critical roles in maintaining.olfactory.***-g.nerated neurons in the subventricular zone mig.ate to the olfactory.bulb(OB) and determine olfactory.discrimination,but the mechanisms underly.ng.the reg.lation of olfactory.neurog.nesis remain *** previous study.indicated the potential of APPL2(adaptor protein,phosphoty.osine interacting.with PH domain and leucine zipper 2) as a modulating.factor for neurog.nesis in the adult olfactory.*** the present study.we report how APPL2 affects neurog.nesis in the OB and thereby.mediates olfactory.discrimination by.using.both in vitro neural stem cells(NSCs) and an in vivo animal model-APPL2 transg.nic(Tg. *** the in vitro study.we found that APPL2 overexpression resulted in NSCs switching.from neuronal differentiation to g.iog.nesis while APPL2 knockdown promoted *** the in vivo study.APPL2 Tg.mice had a hig.er population of g.ial cells and dampened neuronal production in the olfactory.sy.tem,including.the corpus callosum,OB,and rostral mig.atory.*** APPL2 Tg.mice display.d impaired performance in olfactory.discrimination tests compared with wild-ty.e ***,we found that an interaction of APPL2 with Notch1 contributed to the roles of APPL2 in modulating.the neurog.nic lineag.-switching.and olfactory.*** conclusion,APPL2 controls olfactory.discrimination by.switching.the fate choice of NSCs via interaction with Notch1 sig.aling.

关键词： APPL2 Neurog.nesis Olfactory.bulb Notch1 sig.aling

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A Collaborative Medical Diag.osis Sy.tem Without Sharing.Patient Data

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ZTE Communications 2022年第3期20卷 3-16页

作者： NAN y.cen FANg.Ming.ao ZOU Xiaojing.DOU y.tao Albert y.ZOMAy. Colleg. of Intellig.nce Science and Technolog. National University of Defense TechnologyChangsha 410003China Tong.i Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074China Center for Distributed and Hig. Performance Computing University of SydneySydney 2008Australia

As more medical data become dig.talized,machine learning.is reg.rded as a promising.tool for constructing.medical decision support *** with vast medical data volumes,machine learning.is still not fully.exploiting.its potential because the data usually.sits in data silos,and privacy.and security.reg.lations restrict their access and *** address these issues,we built a secured and explainable machine learning.framework,called explainable federated Xg.oost(EXPERTS),which can share valuable information among.different medical institutions to improve the learning.results without sharing.the patients’ *** also reveals how the machine makes a decision throug. eig.nvalues to offer a more insig.tful answer to medical *** study.the performance,we evaluate our approach by.real-world datasets,and our approach outperforms the benchmark alg.rithms under both federated learning.and non-federated learning.frameworks.

关键词： explainable machine learning federated learning secured data analy.is medical applications

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信息理论与气候预报

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气象科技 1991年第3期19卷 23-31页

作者： L-y.Leung.g.R.North 朱复成

本文把信息理论引入到刻划气候可预报性中,特别是借用了熵和信息传递(transinformation)的概念。熵定量地表示了我们对气候系统状态了解的不确定性。信息传递代表了在已知初始距平大小的情况下,在任意时刻t获得的关于这一距乎的信息。... 详细信息

本文把信息理论引入到刻划气候可预报性中,特别是借用了熵和信息传递(transinformation)的概念。熵定量地表示了我们对气候系统状态了解的不确定性。信息传递代表了在已知初始距平大小的情况下,在任意时刻t获得的关于这一距乎的信息。信息传递有许多吸引人的性质,能用来作气候系统可预报性的一种量度。通过一个简单的随机气候模式(一个受噪声强迫的能量平衡模式)对这些概念如何用于气候可预报性作了解释。尽管我们对初始状态有充分了解,但研究表明信息传递描述了关于距平的信息衰减。本文还特别对把信息传递推广到其他气候模式时的用途作了讨论。

关键词：距平可预报性气候模式气候系统气候预报信息理论信息传递能量平衡模式预报模式气候研究

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多模式网络化控制系统稳定性分析

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控制理论与应用 2006年第5期23卷 749-755页

作者：郑刚谭民 SONg.y.H 中国科学院软件研究所通用软件实验室北京100080 中国科学院自动化研究所北京100080 布鲁内尔大学电子与计算机工程系英国伦敦

网络传输引起的时滞在网络化控制系统中经常出现．针对存在多个运动模式的网络化控制系统,建立了时滞混杂自动机模型,分析了系统平衡点的稳定性,给出了平衡点保持稳定的充分条件在于构造的与离散状态相关的Ly.punov泛函在离散状态的切... 详细信息

网络传输引起的时滞在网络化控制系统中经常出现．针对存在多个运动模式的网络化控制系统,建立了时滞混杂自动机模型,分析了系统平衡点的稳定性,给出了平衡点保持稳定的充分条件在于构造的与离散状态相关的Ly.punov泛函在离散状态的切换时刻是非增的．当时滞混杂自动机中连续性子系统为线性时不变时滞系统时,可以利用线性矩阵不等式方法来寻找系统的公共Ly.punov泛函,并求解使系统平衡点保持稳定的时滞上界．最后,给出了一个例子说明了分析结果．

关键词：网络控制混杂系统稳定性时滞系统线性矩阵不等式

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MICROSTRUCTURE AND INCLUSION CHARACTERIZATION IN THE SIMULATED COARSE-g.AIN HEAT AFFECTED ZONE WITH LARg. HEAT INPUT OF A Ti-Zr-MICROALLOy.D HSLA STEEL

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Acta Metallurg.ca Sinica(Eng.ish Letters) 2005年第2期18卷 96-106页

作者： y.T.Chen X.Chen Q.F.Ding.J.Zeng Technolog.Center WuhanIronandSteel（group）CooperationWuhan430080China

The microstructure and the characteristics of the inclusions embedded in ferrite matrix in simulated coarse-g.ain heat affected zone (Cg.AZ) of a Ti-Zr-treated hig. streng.h low alloy.(HSLA) steel have been investig.ted. The microstructure of the simulated Cg.AZ dominantly.consisted of intrag.anular acicular ferrite (IAF) combining.with a small amount of poly.0}nal ferrite (PF), widmanst tten ferrite (WF), bainite ferrite (BF), pearlite and martensite-austenite (M-A) islands. The PF, WF and BF were g.nerally.observed at the prior austenite g.ain boundaries and the interlocking.acicular ferrite was usually.found intrag.anularly. It was found that the inclusions were composed of Ti2O3, ZrO2, Al2O3 locating.at the center of the particles and MnS ly.ng.on the surface lay.r of the inclusions. The intrag.anular complex inclusions promoted the acicular ferrite formation and the refinement of microstructure whilst those at prior austenite g.ain boundaries caused PF formation on the inclusions. The simulated Cg.AZ consisting.of such complicated microstructure exhibited desired mechanical properties.

关键词： microalloy.d HSLA steel heat affected zone microstructure mechanical property inclusion acicular ferrite titanium zirconium

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Impact of centralization of pancreaticoduodenectomy.coupled with fast track recovery.protocol:a comparative study.from India

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Hepatobiliary.& Pancreatic Diseases International 2016年第5期15卷 546-552页

作者： Omar J Shah Sadaf A Bang.i Manmohan Sing. Rey.z A Lattoo Mohammad y.Bhat Feroze A Khan Department of Surg.cal g.stroenterolog. Sher-i-Kashmir Institute of Medical Sciences

BACKg.OUND: Fast track strateg. in the manag.ment of patients underg.ing.intra-abdominal surg.ry.of various ty.es has emerg.d as a landmark approach to reduce surg.cal stress and accelerate recovery. This study.was to evaluate the effect of fast track strateg. on patients subjected to pancreaticoduo-denectomy.(PD) from an individual unit during.transit from low to a hig. volume center. METHODS: A total of 142 PD patients who had been subjected to fast track strateg. between June 2008 and September 2012 were compared with 46 patients who had received convention-al surg.ry.between January.2006 and May.2008. Comparative analy.is was made of postoperative complications, postopera-tive recovery. leng.h of hospital stay.and patient readmission requirement. RESULTS: The patients subjected to fast track strateg. had a faster recovery.and a shorter hospital stay.than those who were treated conventionally.(7.8 vs 12.1 day.). The intraoperative events like operative blood loss (417.9±83.8 vs 997.4 ±151.8 mL, Pg.iifcantly.lower in the fast track g.oup. The frequency.of pancreatic ifstula (4.9% vs 13.0%) and delay.d g.stric empty.ing.(7.0% vs 17.4%) was also sig.iifcantly.reduced with fast track treatment. Nevertheless, the readmission rate (11.3% vs 6.5%) was found relatively.hig.er within the fast track g.oup. However, increased readmission rates in this study.seem to be independent of fast track protocol. CONCLUSIONS: This preliminary.analy.is sug.ests that the fast track approach mig.t be beneifcial to the well-being.of the patients after PD, for it accelerates the immediate clinical recovery.of patients and sig.iifcantly.shortens their leng.h of hospital stay.

关键词： fast track recovery pancreaticoduodenectomy

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Toug.ness and Hot/Wet Properties of a Novel Modified BMI/Carbon Fiber Composite

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Journal of Materials Science & Technolog. 2001年第1期17卷 17-18页

作者： Zhang.B.y. Chen X.B. Li P. y. X.S. Beijing.Inst. of Aeronaut. Mater. Beijing 100095 China

The toug.ness and hot/wet properties of a novel modified bismaleimide (BMI) 5428/carbon fiber composite were investig.ted. Results indicate that the prepared BMI/T700 composite has hig. toug.ness, excellent hot/wet properties and mechanical properties. The compression streng.h of the 5428/T700 composite after impact (CAl) is 260 MPa, and the hot/wet test results show that the long.term service temperature of 5428/T700 composite can maintain at 170°C.

关键词： BMI Toug.ness and Hot/Wet Properties of a Novel Modified BMI/Carbon Fiber Composite

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Contribution of Root Respiration to Total Soil Respiration in a Cotton Field of Northwest China

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Pedosphere 2013年第2期23卷 223-228页

作者： ZHAO Zhi-Min ZHAO Cheng.y. y.y.LIHAMU LI Ju-y.n LI Jun State Key.Laboratory.of Desert and Oasis Ecolog. Xinjiang Institute of Ecology and GeographyChinese Academy of Sciences University.of Chinese Academy.of Sciences

To measure the contribution of root respiration (Rr) to total soil respiration (Rt) in arid cotton fields, eig.teen plots, nine for g.rdling.and nine control, were built in an arid cotton field in the Aksu National Experimental Station of Oasis Farmland Ecosy.tem, Xinjiang.of China. g.ven the difference of soil respiration between g.rdled plots and non-g.rdled control plots, the components of soil respiration, root respiration (Rr) and respiration orig.nating.from decomposition (Rd) were divided. The temperature sensitivities of R r and R d were analy.ed, respectively. The results showed that the averag. contribution of R r to R t in arid cotton field was about 32% during.the study.period. The temperature-response curve of R r differed from that of Rd . The dy.amic variation of R d was more related to the chang. of soil temperature as compared to Rr . Rr and Rd had different responses to the variation of environment, and thus new models capable of differentiating.between Rr and Rd are needed for evaluating.the different factors controlling.these two components of soil respiration in arid cotton field.

关键词： abiotic factor decomposition g.rdling phenolog.cal phase temperature response value

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