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Foot reflexolog. in autoimmune diseases:Effectiveness and mechanisms

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World Journal of Clinical Cases 2025年第7期13卷 1-5页

作者： Jozélio Freire de Carvalho Aaron Lerner Carina Benzvi Núcleo de Pesquisa em Doenças Crônicas não Transmissíveis Federal University of BahiaSalvador 40231-300BahiaBrazil Department of Research Chaim Sheba Medical CenterThe Zabludowicz Research Center for Autoimmune DiseasesRamat Gan 52621Israel

Foot reflexolog.(FR)is a Chinese-orig.nated and non-invasive complementary therapy increasing.y used by functional,alternative and para-medical *** attempts are made to study FR in non-functional org.nic *** present invited Editorial discusses the application of FR in autoimmune diseases(AD),hig.lig.ting.a few successful studies demonstrating.symptomatic relief and objective *** promising.results,the FR domain remains under-investig.ted and an urg.nt need to confirm and understand the effect of FR in chronic diseases,including.AD,is hig.ly recommended.

关键词： Reflexolog. Foot reflexolog. Sensorineural hearing.loss Autoimmune diseases Autoimmunity

Effects of different cue positions on evoked potentials in the cerebral cortex during.g.obal and local processing.of compound stimuli A study of event-related potential

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Neural Reg.neration Research 2009年第11期4卷 941-946页

作者： Xuemin Zhang.Yong.a lio Siyu Bai Yaqin Zheng School of Psycholog. State Key Laboratory of Cognitive Neuroscience and Learning Beijing Normal University Beijing 100875 China Department of Psycholog. New York State University Albany 12246 New York USA Department of Educational Psycholog. Xuchang University Xuchang 461000 Henan Province China

BACKg.OUND： Previous studies of attentional control have focused primarily on pre-cue control of attentional cue and direction. OBJECTIVE： To measure the differences in electrical activity of brain cells while processing.pre-cue and post-cue compound stimuli, and to explore brain electrical activity during.g.obal and local processing.of compound stimuli according.to electroencephalog.am （EEg. recording.. DESIg., TIME AND SETTINg. A within-subject desig. study was performed at the School of Psycholog., State Key Laboratory of Cog.itive Neuroscience and Learning. Beijing.Normal University, China from March to May 2006. PARTICIPANTS： A total of 30 healthy, underg.aduate students, ag.d 17-24 years, comprising.12 males and 18 females, were voluntarily enrolled from Beijing.Normal University. Subjects exhibited normal or corrected-to-normal visual acuity. No sig.ificant non sig.al wave drift was detected during.testing. METHODS： A total of 30 subjects were subjected to pre-cue and post-cue compound stimulus processing.using.event-related potential and EEg.recording.. MAIN OUTCOME MEASURES： Evoked potential was recorded in different brain reg.ons utilizing.event-related potential to observe hemispheric symmetry, cue consistency and g.obal-local features. RESULTS： Pre-cue compound stimuli resulted in hemispheric asymmetry for early wave （N1） and late wave （P3） in anterior brain reg.ons. Early- and late-wave induced hemispheric asymmetry for electrode points （O1, 02, P3, P4, Pz, F3, F4, F7, F8, Fz, FP1, FP2, T7, TS, C3, C4, and Cz） during.processing.of pre-cue compound stimuli （P 〈 0.05）. Post-cue compound stimuli did not induce hemispheric asymmetry of brain waves induced by the above-described electrode points. No sig.ificant differences in g.obal and local responses were determined during.processing.of post-cue compound stimuli. Under pre-cue conditions, sig.ificant differences were observed in N1 and P3 in the above-mentioned electrode points （P 〈 0.05）. However, under p

关键词： compound stimuli cue event-related potential hemispheric symmetry attention

Etiolog. of g.anulomatous inflammation:A retrospective study of 174 children in a tertiary care center

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Asian Pacific Journal of Tropical Medicine 2022年第11期15卷 511-517页

作者： Ummühan Cay Derya Alabaz ÖzlemÖzg.r g.ndeşlioğlu Aysun Hatice Ug.z Hande Yanar Department of Pediatric Infectious Diseases Faculty of MedicineÇukurova UniversityAdanaTurkey Department of Patholog. Faculty of MedicineÇukurova UniversityAdanaTurkey

Objective:To investig.te g.anulomatous inflammation etiolog. based on clinical history and ancillary ***:Children ag.d<18 years with biopsy proven g.anulomatous lesions in any tissue specimens between January 2014 and... 详细信息

Objective:To investig.te g.anulomatous inflammation etiolog. based on clinical history and ancillary ***:Children ag.dg.anulomatous lesions in any tissue specimens between January 2014 and January 2022 were included in the *** diag.osis was based on the results of immunohistochemical staining.molecular tests,culture,serolog.,radiolog.cal and other auxiliary laboratory *** were categ.rized into infectious and noninfectious ***:In total,174 patients with g.anulomatosis inflammation confirmed by histopatholog. were *** 59.2%patients were males,and the median ag. was 4.48(IQR 2.36-6.39)years(rang.:16 months-18 years).The tissues/org.ns that were most commonly biopsied were lymph node,bone,skin,and lung.51.1%,17.8%,9.2%,and 5.7%,respectively).Infectious and non-infectious causes were identified in 73.0%and 12.6%patients,respectively,in terms of g.anulomatosis inflammation etiolog.;however,no cause was identified in 14.4%*** most common infectious cause was tuberculosis(in 51.7%patients),followed by toxoplasmosis,asperg.llosis,mucormycosis,leishmaniasis,and cat-scratch disease(in 8.6%,5.7%,1.7%,1.7%,and 1.1%patients,respectively).The common non-infectious cause was chronic g.anulomatous *** evaluation revealed g.anulomatosis inflammation in 33.3%patients,necrotizing.g.anulomatosis inflammation in 30.5%patients,and caseating.g.anulomatosis inflammation in 12.1%*** the patholog. results of patients with and without tuberculosis were compared,the incidence of caseating.g.anulomatosis inflammation(P=0.003)and necrotizing.g.anulomatosis inflammation(P=0.005)was hig.er in patients with ***:Chronic g.anulomatous disease is the most common non-infectious cause in ***,primary or secondary immune deficiencies may cause g.anulomatosis inflammation,especially in pediatric patients.

关键词： g.anulomatous Children Tuberculosis Chronic g.anulomatous disease

Three-year follow-up in advanced pediatric keratoconus:thin corneas may not have pachymetry properly assessed after crosslinking

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International Journal of Ophthalmolog.(Eng.ish edition) 2020年第10期13卷 1561-1566页

作者： Rosalia Antunes-Foschini Sidney Júlio Faria-e-Sousa Hospital das Clínicas Medical School of Ribeirao PretoUniversity of Sao PauloRibeirao Preto 14049-900Brazil Department of Ophthalmolog. OtorhinolaryngologyHead and Neck SurgeryMedical School of Ribeirao PretoUniversity of Sao PauloRibeirao Preto 14049-900Brazil

AIM:To analyze the crosslinking.CXL)effects in pediatric keratoconus,and to identify the patients’corneal characteristics whose pachymetry could not be adequately evaluated by Scheimpflug.method after ***:Consecutive pediatric patients with prog.essive keratoconus underwent CXL were ***-corrected visual acuity(BCVA)and spheric equivalent(SE)were measured before and after *** CXL,g.oups 1 and 2 were divided based on the posterior surface Pentacam quality specifications(QS):"OK"(g.oup 1)and"not OK"(g.oup 2).The mean(RmF and RmB)and minimum(RminF and RminB)radius of curvatures of the anterior and posterior corneal surfaces,and the thinnest pachymetry(Pmin)were measured preoperatively at 3,6,12,24,and 36 *** was ***:Twenty-six patients(14 men,mean ag. 14±1.8 y)and median Kmax of 59.9 D initially and 61.4 D preoperatively were *** was not different before and 24 mo after *** 2 statistically differed to g.oup 1 in that SE was more myopic before and with no difference 24 mo after CXL;RmF and RmB were steeper and Pmin was thinner *** 2,in which pachymetric chang.s could not be adequately evaluated after surg.ry,presented with sig.ificant RmF flattening.a shift to hyperopia,and more haze after ***:Patients whose pachymetry could not be adequately evaluated after CXL had steeper and thinner corneas before *** predictive factors for impaired QS after CXL are RmF,RmB,and *** advanced keratoconus,alternative methods to analyze pachymetry and the posterior surface should be considered.

关键词： keratoconus cross-linking corneal pachymetry corneal topog.aphy corneal opacity

Introduction to the Special Issue on Computer-Aided Uncertainty Modeling.and Reliability Evaluation for Complex Eng.neering.Structures

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Computer Modeling.in Eng.neering.& Sciences 2024年第10期141卷 1-5页

作者： Debiao Meng.Abílio Manuel Pinho de Jesus Zeng.Meng School of Mechanical and Electrical Eng.neering University of Electronic Science and Technology of ChinaChengdu611731China INEg. Faculty of EngineeringUniversity of PortoPorto4200-465Portugal School of Civil Eng.neering Hefei University of TechnologyHefei230009China

1 Summary With the advancement of science and technolog.,complex eng.neering.structures are widely used in extreme environments[1].In equipment service,many uncertainty factors sig.ificantly affect safety and reliability[2–5].Therefore,ensuring.hig. reliability of structures has become an important research direction in eng.neering.*** the same time,the importance of equipment health manag.ment of complex eng.neering.structures is becoming.increasing.y prominent[6–8].Computer-aided uncertainty modeling.and reliability assessment have become key tools,and finite element simulation and alg.rithmic innovation play a key role in the reliability analysis of complex equipment[9,10].These techniques can accurately simulate stress and damag. accumulation under various operating.environments,providing.eng.neers with important decision support and optimization solutions.

关键词： extreme Reliability environments

Archean-Ediacaran evolution of the Campos g.rais Domain-A reworked marg.n of the São Francisco paleocontinent(SE Brazil):Constraints from metamafic-ultramafic rocks

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g.oscience Frontiers 2022年第5期13卷 286-308页

作者： Marco Aurélio Piacentini Pinheiro g.org. L.g.ice Joana Reis Mag.lhães g.olog.cal Survey of Brazil–CPRM Av Brazil 1731Belo Horizonte 30140-002Brazil Department of Mineral Sciences National Museum of Natural HistorySmithsonian Institution10th Street and Constitution Avenue NWWashington D.C.20560USA

The Campos g.rais Domain(Cg.)in southeastern Brazil is an approximately 180 km×35 km area of Archean–Proterozoic rocks located southwest of the São Francisco Craton(SFC).The Archean–Paleopro terozoic evolution of the Cg.—along.ide its potential correlation with the SFC or other cratonic blocks in the reg.on-is currently *** present the results of systematic petrog.aphy,bulkrock g.ochemistry,mineral chemistry and g.ochronolog. for a suite of scarcely studied mafic–ultramafic rocks from the *** also provide a compilation of previously reported bulk-rock g.ochemical and spinel g.oup mineral chemical data for mafic–ultramafic rocks throug.out the Cg.,and g.ochronolog.cal information for various lithotypes in the *** Cg. records a protracted Mesoarchean to Statherian(3.1–1.7 g.)crustal evolution,which we interpret to share a common history with the southern SFC and their related reworked seg.ents,sug.esting.that it is a westward extension of this cratonic *** metavolcano-sedimentary rocks of the Fortaleza de Minas and Alpinópolis seg.ents represent a Mesoarchean g.eenstone belt that is stratig.aphically and chemically comparable to Archean g.eenstone belts worldwide,and that is broadly coeval with a local suite of tonalite-trondhjemite-g.ano diorite(TTg.g.eisses and mig.atites.U-Pb SHRIMP zircon data from a subalkaline metag.bbro yielded a concordia ag. of ca.2.96 g.,revealing.a previously unrecog.ized phase of Archean mag.atism in the Cg. that can be chrono-correlated with metakomatiite and TTg.g.neration elsewhere in the São Francisco *** data contradict a hypothesis whereby the metavolcano-sedimentary rocks of the Jacuí-Bom Jesus da Penha and Petúnia seg.ents represent an ophiolite,as previously sug.ested,instead presenting.features that point to formation in association with a continental *** with a U-Pb(SHRIMP)crystallization ag. of ca.2.13 g. recorded by zircon g.ains from a metaultramafic rock,these data h

关键词： Komatiites São Francisco Craton Southern Brasília Orog.n Archean g.odynamics Rhyacian orog.ny

Biobased polyurethanes for biomedical applications

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Bioactive Materials 2021年第4期6卷 1083-1106页

作者： Sophie Wendels Luc av´erous BioTeam/ICPEES-ECPM UMR CNRS 7515Universit´e de Strasbourg25 Rue Becquerel67087Strasbourg Cedex 2France

Polyurethanes(PUs)are a major family of polymers displaying.a wide spectrum of physico-chemical,mechanical and structural properties for a larg. rang. of *** have shown suitable for biomedical applications and are used in this domain since *** current variety of biomass available has extended the diversity of starting.materials for the elaboration of new biobased macromolecular architectures,allowing.the development of biobased PUs with advanced properties such as controlled biotic and abiotic *** this frame,new tunable biomedical devices have been successfully *** structures with precise tissue biomimicking.can be obtained and are adequate for adhesion,proliferation and differentiation of many cell’s ***,new smart shape-memory PUs with adjustable shape-recovery properties have demonstrated promising.results for biomedical applications such as wound *** fossil-based starting.materials substitution for biomedical implants is slowly improving.nonetheless better renewable contents need to be achieved for most PUs to obtain biobased *** a presentation of some PU g.neralities and an understanding.of a biomaterial structure-biocompatibility relationship,recent developments of biobased PUs for non-implantable devices as well as short-and long.term implants are described in detail in this review and compared to more conventional PU structures.

关键词： Polyurethanes Biobased Biomedical Bioactive Tissue eng.neering Biocompatibility Scaffold

Lidocaine in fibromyalg.a:A systematic review

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World Journal of Psychiatry 2022年第4期12卷 615-622页

作者： Jozélio Freire de Carvalho Thelma L Skare Health Sciences Institute Federal University of BahiaSalvador 40231-300Brazil Rheumatolog. Unit Evangélico Mackenzie HospitalCuritiba 80730-420Brazil

BACKg.OUND Fibromyalg.a(FM)patients are treated with antidepressants,and in most cases,these drug. lose efficacy or present side *** lidocaine(IL)is an anesthetic drug.used in some FM *** To systematically review the safety and efficacy of IL in FM *** To systematically search PubMed for articles in Eng.ish,Spanish,and Japanese with Eng.ish Abstracts on FM and lidocaine between 1966 and February *** study was reg.stered at *** We found only ten articles published in this field,with a total of 461 *** predominated varying.from 95%to 100%in the *** varied from 40.9 to 55 years *** duration varied from 1 mo to 6.4 *** dose varied from 2 to 7.5 mg.kg.via intravenous ***-up period varied from 65.7 to 90 *** outcomes,most studies used the visual analog.e scale(VAS)for pain;before short-term lidocaine administration,VAS was between 6.1 and 8.1 and after treatment was between 1.7 and 4.5 *** long.term lidocaine,VAS varied from 30%to 35.4%after lidocaine *** effects were observed in 0%to 39.6%of cases,they were usually mild or *** This study demonstrates the short-term effectiveness and safety of intravenous lidocaine in FM ***,more studies,including.long.term follow-up,are still needed.

关键词： Lidocaine Fibromyalg.a Pain Intravenous infusions

A Chemical Dealloying.Approach for Pt Surface-enriched Pt_(3)Co Alloy Nanoparticles as Oxyg.n Reduction Reaction Electrocatalysts

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Chemical Research in Chinese Universities 2022年第4期38卷 991-998页

作者： CHEN Yuanda CHEN Yong.ing.lio Yuxiang.CHEN Sheng.i Colleg. of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power SourcesWuhan UniversityWuhan430072P.R.China

Pt-based alloys are the optimal electrocatalysts for oxyg.n reduction reaction(ORR)*** of Pt-based alloys has shown to be an effective approach to improving.ORR *** dealloying.is controllable for morpholog. by chang.ng.electrochemical parameters but is difficult to scale up due to complex operation and energ. *** dealloying.is suitable for a larg. scale but it is not easy to control the morpholog. because hig.ly corrosive acids(HNO_(3) or H2SO4)are commonly *** this work,a facile chemical dealloying.method for Pt_(3)Co/C has been employed to synthesize electrocatalysts for ORR using.weak acids and buffer solutions of different pH,which could slow down the dissolution rate for Co atoms and increase the diffusion time for Pt atoms to improve ORR *** can be observed that the mass activities(MA)of the Pt_(3)Co/C alloy after dealloying.with H3PO4 and NaH2PO4/Na2HPO4 buffer solution of pH=6 are close to that after electrochemical dealloying.process,and are more than two times that of commercial Pt/*** addition,Pt_(3)Co/C after dealloying.with a buffer solution of pH=6 only showed a slig.t deg.adation in the half-wave potential and electrochemical surface area(ECSA)after stability test for 5000 cycles,which is more stable than commercial Pt/*** shows that by controlling.pH of the solvent,the ORR activity can be further *** facile approach provides a new strateg. to control morpholog. of Pt-based electrocatalysts by chemical dealloying.which can contribute to promising.application for cathodic electrocatalysts desig. of proton exchang. membrane fuel cells(PEMFCs).

关键词： Oxyg.n reduction reaction(ORR) Chemical dealloying Electrochemical dealloying Pt-based alloy