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Towards a fast and stable tachypnea monitor:a C_(60)-Lys enabled optical fiber sensor for humidity tracking in breath progress

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Chinese Optics Letters 2024年第2期22卷 101-108页

作者：王富祥高峰王小牛王莹金飞任紫峭武俊黄振林周文俊沈常宇 College of Optical and Electronic Technology China Jiliang UniversityHangzhou 310018China College of Materials and Chemistry China Jiliang UniversityHangzhou 310018China

The pandemic of respiratory diseases enlightened people that monitoring respiration has promising prospects in averting many fatalities by tracking the development of ***,the response speed of current optical fiber sensors is still insufficient to meet the requirements of high-frequency respiratory detection during respiratory ***,a scheme for a fast and stable tachypnea monitor is proposed utilizing a water-soluble C_(60)-Lys ion compound as functional material for the tracking of humidity change in the progression of *** polarization of C_(60)-Lys can be tuned by the ambient relative humidity change,and an apparent refractive index alteration can be detected due to the small size *** our experiments,C_(60)-Lys is conformally and uniformly deposited on the surface of a tilted fiber Bragg grating(TFBG)to fabricate an ultra-fast-response,high-sensitivity,and long-term stable optical fiber humidity sensor.A relative humidity(RH)detecting sensitivity of 0.080 dB/%RH and the equilibrium response time and recovery time of 1.85 s and 1.58 s are observed,***,a linear relation is detected between the resonance intensity of the TFBG and the environment *** a practical breath monitoring experiment,the instantaneous response time and recovery time are measured as 40 ms and 41 ms,respectively,during a 1.5 Hz fast breath ***,an excellent time stability and high repeatability are exhibited in experiments conducted over a range of 7 days.

关键词： humidity sensor fullerene derivative optical fiber sensing tilted fiber Bragg grating nanomaterials

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肠道菌群对抗性淀粉的降解机制

中国食品学报 2024年第1期24卷 364-378页

作者：王扶香莫剑慧胡新中马蓁陕西师范大学食品工程与营养科学学院西安710119

抗性淀粉是指不能被健康人体小肠消化酶酶解,而进入结肠的一类复杂碳水化合物,可通过发酵及促进结肠微生物增殖,带给人体诸多健康益处。人体肠道中微生物种类繁多,这些微生物降解抗性淀粉的机理得到国内外学者的关注。本文结合国内外关... 详细信息

抗性淀粉是指不能被健康人体小肠消化酶酶解,而进入结肠的一类复杂碳水化合物,可通过发酵及促进结肠微生物增殖,带给人体诸多健康益处。人体肠道中微生物种类繁多,这些微生物降解抗性淀粉的机理得到国内外学者的关注。本文结合国内外关于抗性淀粉的研究进展,对抗性淀粉的分类、结构、产生酶抗性的机理及其生理功能进行概述,重点阐述抗性淀粉和肠道菌群的相互作用,探讨2种初级降解菌(即布氏瘤胃球菌和双歧杆菌)对抗性淀粉的降解机制,以及部分次级微生物在降解抗性淀粉中的作用,旨在为开发特定代谢功能的抗性淀粉型复杂碳水化合物,以及合理选择健康食品的目标功能化设计提供理论指导。

关键词：抗性淀粉肠道菌群降解机制

Successful treatment of severe monkeypox case with advanced HIV infection using plasma from smallpoxvaccinated healthy population:A case report

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iLABMED 2024年第1期2卷 60-66页

作者： Chuming Chen Weiming Yao Siran Huang Ling Peng Shiyan Feng Weibo Wu Yunlan Yi Zhiqiang Cheng Yang Yang Yan Yang Liuqing Yang Hongzhou Lu fuxiang wang Department of Infectious Diseases National Clinical Research Center for Infectious DiseaseShenzhen Third People's HospitalThe Second Affiliated HospitalSchool of MedicineSouthern University of Science and TechnologyShenzhenGuangdongChina Department of Pathology National Clinical Research Center for Infectious DiseaseShenzhen Third People's HospitalThe Second Affiliated HospitalSchool of MedicineSouthern University of Science and TechnologyShenzhenGuangdongChina Department of Blood Transfusion National Clinical Research Center for Infectious DiseaseShenzhen Third People's HospitalThe Second Affiliated HospitalSchool of MedicineSouthern University of Science and TechnologyShenzhenGuangdongChina

Since the first reported case of monkeypox in the UK in May 2022,there has been an upward trend in monkeypox cases and a global ***,reports of severe cases are relatively *** this study,we report a case of severe monkeypox in a patient with *** patient presented with skin lesions that started on his face and around the penis and persisted for several *** the course of the disease,he received systematic symp-tomatic supportive treatment,topical remedies,and special care for the *** also underwent cidofovir antiviral therapy and smallpox‐vaccinated healthy population‐derived plasma therapy in succession,with the condition ultimately showing improvement after plasma *** more than 3 months of hospitalization,he fully *** the best of our knowledge,this is the first reported use of smallpox‐vaccinated healthy population‐derived plasma in the treatment of severe monkeypox cases.

关键词： antiviral therapy co‐infection HIV monkeypox plasma therapy severe infection

Index Geographic Gossip Algorithm for Information Dissemination over Regular Graphs

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Chinese Journal of Electronics 2019年第2期28卷 386-391页

作者： wang Gang LIN Zun wang fuxiang School of Electrical and Information Engineering Beihang University China Mobile Communications Group Co.Ltd

An Index geographic gossip(IGG)algorithm is proposed. Relay nodes participate in information exchange and updating. The cumulative number of times these nodes participate is characterized by an index number, which can be used to accelerate information updating. The convergence property of the IGG algorithm is theoretically analyzed in ring and grid network topologies. The IGG algorithm improves the standard gossip algorithm by a gain of O(n) in both convergence time and communication cost. Compared to the geographic gossip algorithm, the IGG algorithm has a gain on the order of O(n) and O(n1/2) in the average hop count for information exchange and communication cost, respectively. Finally, the proposed IGG algorithm is compared with various baselines through simulations,and it is shown that significant performance gain can be achieved.

关键词： Information dissemination Gossip algorithm Node mobility Geography

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基于有限元的管道凹陷回弹与回圆分析

中国安全生产科学技术 2024年第4期20卷 163-171页

作者：杨辉臧红王富祥张银辉国家管网集团科学技术研究总院分公司河北廊坊065000 新奥科技发展有限公司河北廊坊065000

为了明确回弹与回圆行为对管道结构完整性的影响,解决不同约束状态下管道凹陷适用性评价结果的差异性问题,建立模拟3种管型在2类压头作用下凹陷成型-回弹-回圆全过程的三维有限元模型,系统地探讨管型、管径、壁厚、压头类型、压头尺寸... 详细信息

为了明确回弹与回圆行为对管道结构完整性的影响,解决不同约束状态下管道凹陷适用性评价结果的差异性问题,建立模拟3种管型在2类压头作用下凹陷成型-回弹-回圆全过程的三维有限元模型,系统地探讨管型、管径、壁厚、压头类型、压头尺寸、凹陷位置、螺距等对凹陷回弹率和回圆率的影响,采用非线性回归函数拟合得出不同类型管道回弹系数和回圆系数经验公式。研究结果表明:凹陷的回弹与回圆行为受管道结构刚度、凹陷形貌、尺寸、位置及内压等多因素影响,导致不同约束状态下凹陷变形历程和评价保守性差异;误差分析显示拟合预测精度较好。研究结果可用于基于内检测的凹陷深度的预测与评价。

关键词：凹陷回弹回圆有限元非线性回归内检测

Novel infrared and visible image fusion method based on independent component analysis

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Frontiers of Computer Science 2014年第2期8卷 243-254页

作者： Yin LU fuxiang wang Xiaoyan LUO Feng LIU National Key Laboratory of CNS/ATM School of Electronics and Information Engineering Beihang University Beijing 100191 China

The goal of infrared （IR） and visible image fu- sion is for the fused image to contain IR object features from the IR image and retain the visual details provided by the visible image. The disadvantage of traditional fusion method based on independent component analysis （ICA） is that the primary feature information that describes the IR objects and the secondary feature information in the IR image are fused into the fused image. Secondary feature information can de- press the visual effect of the fused image. A novel ICA-based IR and visible image fusion scheme is proposed in this paper. ICA is employed to extract features from the infrared image, and then the primary and secondary features are distinguished by the kurtosis information of the ICA base coefficients. The secondary features of the IR image are discarded during fu- sion. The fused image is obtained by fusing primary features into the visible image. Experimental results show that the pro- posed method can provide better perception effect.

关键词： image fusion independent component analysis(ICA) feature extraction kurtosis

采血机器人在HIV感染者随访门诊应用障碍及促进因素的质性研究

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中国艾滋病性病 2024年第7期30卷 693-698页

作者：石义容陈伟梅朱玉玲张丽媛王福祥何云深圳市第三人民医院广东深圳518112

目的了解HIV感染者使用采血机器人采血的体验及需求,探索采血机器人应用在HIV感染者随访门诊的障碍及促进因素。方法采用描述性质性研究方法,以目的抽样法选取2023年6月深圳市第三人民医院18个应用采血机器人采血的HIV感染者为研究对... 详细信息

目的了解HIV感染者使用采血机器人采血的体验及需求,探索采血机器人应用在HIV感染者随访门诊的障碍及促进因素。方法采用描述性质性研究方法,以目的抽样法选取2023年6月深圳市第三人民医院18个应用采血机器人采血的HIV感染者为研究对象,对患者进行半结构式访谈,根据内容分析法对资料进行分析并提炼主题。结果 18名访谈对象中,男性17例;年龄22~50岁;疼痛评分为0~6分;采血时长为168~251 s;满意17人。障碍因素3个:患者缺乏采血机器人相关知识、人-机-环交互不流畅、人文关怀缺失。促进因素3个:HIV感染者感知益处、感知歧视、应用场景可推广。结论未来可以提高HIV感染者对采血机器人技术认知、提升采血机器人硬件及功能设计,提升采血机器人感受体验,促使患者积极参与采血机器人采血决策。

关键词：采血机器人艾滋病病毒感染者障碍促进因素质性研究

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尼帕病毒的最新研究进展

新发传染病电子杂志 2024年第1期9卷 60-66页

作者：姚伟明王福祥卢洪洲国家感染性疾病临床医学研究中心深圳市第三人民医院(南方科技大学第二附属医院)感染重症科广东深圳518112

尼帕病毒是一种有包膜的多形性病毒,直径40~600nm,属于亨尼帕病毒属,副黏病毒科,单股负链RNA病毒目。病毒能引起人兽共患病,可在人际间传播,并在南亚、东南亚等地多次暴发流行。尼帕病毒主要侵害呼吸系统和中枢神经系统,引起急性发热、... 详细信息

尼帕病毒是一种有包膜的多形性病毒,直径40~600nm,属于亨尼帕病毒属,副黏病毒科,单股负链RNA病毒目。病毒能引起人兽共患病,可在人际间传播,并在南亚、东南亚等地多次暴发流行。尼帕病毒主要侵害呼吸系统和中枢神经系统,引起急性发热、头痛和不同程度的意识障碍,病死率高达40%~75%。尼帕病毒已被世界卫生组织列入其重点病原体蓝图清单,作为8种最危险的病原体之一,需要监测并准备应对措施以防止大流行。然而目前尚缺乏有效的预防疫苗和特效的抗病毒药物,治疗主要依靠系统性对症支持疗法。本文就尼帕病毒在病毒学、致病机制、尼帕病毒感染的临床特征、诊断学、抗病毒药物、疫苗研发和流行病学等方面的最新研究进展展开综述,旨在为未来的研究和防控提供参考。

关键词：尼帕病毒病毒学致病机制临床特征诊断学抗病毒药物疫苗研发流行病学

Striking antibody evasion of SARS-CoV-2 Omicron sub-lineages BQ.1.1, XBB.1 and CH.1.1

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National Science Review 2023年第8期10卷 74-77页

作者： Bin Ju Huimin Guo Miao wang Qing Fan Senlin Shen Xuejiao Liao Jie Jiang Haiyan wang fuxiang wang Zheng Zhang Institute for Hepatology National Clinical Research Center for Infectious Disease Shenzhen Third People's Hospital and The Second Affiliated Hospital School of Medicine Southern University of Science and Technology Guangdong Key Laboratory for Anti-Infection Drug Quality Evaluation Department of Infectious Diseases National Clinical Research Center for Infectious Disease Shenzhen Third People's Hospital and The Second Affiliated Hospital School of Medicine Southern University of Science and Technology Shenzhen Research Center for Communicable Disease Diagnosis and Treatment of the Chinese Academy of Medical Sciences

The recent emergence of various B.1.1.529(Omicron) sub-lineages of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) poses an enormous challenge for the prevention and treatment of coronavirus disease 2019(C... 详细信息

关键词： SUBVARIANTS