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Analysis of resonance asymmetry phenomenon in resonator integrated optic gyro

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Chinese Physics B 2018年第8期27卷 297-300页

作者： Yao Fei Yu-Ming He Xiao-Dong Wang fu-hua yang Zhao-Feng Li Engineering Research Center for Semiconductor Integrated Technology Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China College of Materials Science and Opto-Electronic Technology University of Chinese Academy of ScienceBeijing 100049China School of Microelectronics University of Chinese Academy of SciencesBeijing 100049China

Resonator integrated optic gyro （RIOG） is a high-accuracy gyroscope based on the Sagnac effect. The waveguide- type ring resonator is a key rotation sensing element in the RIOG. An asymmetric resonance line shape is found in the optic resonator. These asymmetries will induce offset errors when the phase modulation spectroscopy technique （PMST） is applied to the RIOG. The polarization errors and the difference among normal mode losses are found to be the two main sources of resonance asymmetry in an experiment. These sources are fully investigated and their contributions to the offset errors are compared. The analysis shows that proper modulation frequencies in clockwise （CW） and counterclockwise （CCW） directions can reduce an RIOG bias error. A transmissive resonator is recommended to obtain a better resonance line shape.

关键词： gyroscopes optical sensing and sensors resonators

Trends and hotspots in gastrointestinal neoplasms risk assessment: A bibliometric analysis from 1984 to 2022

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2842-2861页

作者： Qiang-Qiang fu Le Ma Xiao-Min Niu hua-Xin Zhao Xu-hua Ge hua Jin De-hua Yu Sen yang Department of General Practice Yangpu HospitalSchool of MedicineTongji UniversityShanghai 200090China Shanghai General Practice and Community Health Development Research Center Shanghai 200090China Department of Shanghai Lung Cancer Center Shanghai Chest HospitalShanghai Jiao Tong University School of MedicineShanghai 200030China Department of Oncology Shanghai Tenth People’s HospitalTongji University School of MedicineShanghai 200090China

BACKGROUND Gastrointestinal neoplasm(GN)significantly impact the global cancer burden and mortality,necessitating early detection and *** the evolution and current state of research in this field is *** To conducts a comprehensive bibliometric analysis of publications from 1984 to 2022 to elucidate the trends and hotspots in the GN risk assessment research,focusing on key contributors,institutions,and thematic *** This study conducted a bibliometric analysis of data from the Web of Science Core Collection database using the"bibliometrix"R package,VOSviewer,and *** analysis focused on the distribution of publications,contributions by institutions and countries,and trends in *** methods included data synthesis,network analysis,and visualization of international collaboration *** This analysis of 1371 articles on GN risk assessment revealed a notable evolution in terms of research focus and *** highlights the United States'critical role in advancing this field,with significant contributions from institutions such as Brigham and Women's Hospital and the National Cancer *** last five years,substantial advancements have been made,representing nearly 45%of the examined *** rates have dramatically increased,from 20 articles in 2002 to 112 in 2022,reflecting intensified research *** study underscores a growing trend toward interdisciplinary and international collaboration,with the Journal of Clinical Oncology standing out as a key publication *** shift toward more comprehensive and collaborative research methods marks a significant step in addressing GN *** This study underscores advancements in GN risk assessment through genetic analyses and machine learning and reveals significant geographical disparities in research *** calls for enhanced global collaboration and integration of artificial intelligence to improve cancer p

关键词： Gastrointestinal neoplasms Bibliometric analysis Risk assessment Network analysis Research trends

Effect of Al content in molten steel on interaction between MgO-C refractory and SPHC steel

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Journal of Iron and Steel Research International 2024年第4期31卷 838-848页

作者： fu-bin Gao fu-ming Wang Xiang Zhang Tian-yu Du Xin-hua Wangg School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Handan Iron and Steel Company Hegang GroupHandan 056015HebeiChina The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina

The effect of Al content in molten steel on the interaction between SPHC steel(0.005-0.068 wt.%Al,and 19×10^(-4)-58×10^(-4)wt.%O)and MgO-C refractory(11.63 wt.%C)was ***-metallic inclusions in the steel were examined at various periods(0,5,15,30,45,and 60 min)as well as the MgO-C interface after 60 min of corrosion at 1600℃.The results show that when MgO-C refractory comes into contact with SPHC steel,the refractory interface consists of three layers arranged from the innermost to the outermost,including the original refractory layer,the dense MgO layer,and the iron infiltration *** carbon in the MgO-C refractories and the Al content in the molten steel undergo a reaction with the MgO in the refractories,resulting in an increase in Mg concentration in the *** Al content in the molten steel from 0.005 to 0.068 wt.%causes a spinel layer to appear at the interface,and the disappearance time of Al_(2)O_(3) inclusions in the steel decreases from 60 to 30 min,while the average MgO content in inclusions ***,controlling the Al content in the molten steel and the smelting duration can help regulate the formation of spinel inclusionsinthe steel.

关键词： MgO-C refractory SPHC steel Inclusion-Spinel Al-killed steel Interfacial reaction

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单通道混合信号的深度联合分离译码算法

系统工程与电子技术 2018年第6期40卷 1378-1384页

作者：付君彭华杨勇解放军信息工程大学信息系统工程学院河南郑州450002

针对采用低密度奇偶校验(low density parity check,LDPC)码编码的单通道同频混合信号,提出一种深度联合分离译码算法。采用了Gibbs分离过程中的逐符号分离步骤和译码过程中的逐符号译码步骤之间交替更改变量节点似然软信息的方式,在初... 详细信息

针对采用低密度奇偶校验(low density parity check,LDPC)码编码的单通道同频混合信号,提出一种深度联合分离译码算法。采用了Gibbs分离过程中的逐符号分离步骤和译码过程中的逐符号译码步骤之间交替更改变量节点似然软信息的方式,在初期译码步骤输出的软信息模值较小,便于分离步骤对译码步骤的结果及时进行纠正,降低整体误比特率,软信息达到译码门限后开始发挥译码作用并最终和分离步骤达到一致收敛。仿真结果表明,本文提出的深度联合算法能够有效避免传统迭代分离译码算法由于分离过程的误比特率超出软输入软输出(soft input soft output,SISO)译码器纠错能力范围导致算法无法收敛的现象,降低联合分离译码算法的门限并提升整体性能,对于8PSK调制的混合信号在误比特率为10-3时有1dB的性能改善。

关键词：深度联合单通道盲分离和积译码 Gibbs采样软信息

Clinical outcome and prognostic factors of T4N0M0 colon cancer after R0 resection:A retrospective study

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 1869-1877页

作者： Bang Liu Zhao-Xiong Zhang Xin-yang Nie Wei-Lin Sun Yong-Jia Yan Wei-hua fu Department of General Surgery Tianjin Medical University General HospitalTianjin Medical UniversityTianjin 300052China

BACKGROUND Paradoxically,patients with T4N0M0(stage II,no lymph node metastasis)colon cancer have a worse prognosis than those with T2N1-2M0(stage III).However,no previous report has addressed this *** To screen prognostic risk factors for T4N0M0 colon cancer and construct a prognostic nomogram model for these *** Two hundred patients with T4N0M0 colon cancer were treated at Tianjin Medical University General Hospital between January 2017 and December 2021,of which 112 patients were assigned to the training cohort,and the remaining 88 patients were assigned to the validation *** between the training and validation groups were *** training cohort was subjected to multi-variate analysis to select prognostic risk factors for T4N0M0 colon cancer,followed by the construction of a nomogram *** The 3-year overall survival(OS)rates were 86.2%and 74.4%for the training and validation cohorts,***(P=0.000),T stage(P=0.001),right hemicolon(P=0.025),irregular review(P=0.040),and carbohydrate antigen 199(CA199)(P=0.011)were independent risk factors of OS in patients with T4N0M0 colon cancer.A nomogram model with good concordance and accuracy was *** Enterostomy,T stage,right hemicolon,irregular review,and CA199 were independent risk factors for OS in patients with T4N0M0 colon *** nomogram model exhibited good agreement and accuracy.

关键词： T4N0M0 colon cancer Prognosis Multivariate analysis Nomogram Colon cancer

Transient diabetes mellitus with ABCC8 variant successfully treated with sulfonylurea:Two case reports and review of literature

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World Journal of Diabetes 2024年第8期15卷 1811-1819页

作者： Ling-hua Shen Yan Cui Dong-Xia fu Wei yang Sheng-Nan Wu Hui-Zhen Wang Hai-hua yang Yong-Xing Chen Hai-Yan Wei Department of Endocrinology and Metabolism Henan Key Laboratory of Children's Genetics and Metabolic DiseasesChildren's Hospital Affiliated to Zhengzhou UniversityHenan Children's Hospital Zhengzhou Children's HospitalZhengzhou 450018Henan ProvinceChina

BACKGROUND Transient neonatal diabetes mellitus(TNDM)is a rare form of diabetes mellitus that usually presents within the first 6 mo of *** often enter remission within several months,although relapse can occur later in *** in the ABCC8 gene,which encodes the sulfonylurea receptor 1 of the ATP-sensitive potassium channel in pancreatic beta cells,are associated with TNDM and permanent neonatal *** study describes a novel de novo c.3880C>T heterozygous ABCC8 variant that causes TNDM and can be treated with sulfonylurea *** SUMMARY We retrospectively analyzed 2 Chinese patients with TNDM who were diagnosed,treated,or referred for follow-up between September 2017 and September *** patients were tested for mutations using targeted next-generation *** with neonatal diabetes mellitus caused by a c.3880C>T heterozygous missense variant in the ABCC8 gene have not been reported *** children had an onset of post-infectious diabetic ketoacidosis,which is worth *** a follow-up visit after discontinuing insulin injection,oral glyburide was found to be effective with no adverse *** Early genetic testing of neonatal diabetes mellitus aids in accurate diagnosis and treatment and helps avoid daily insulin injections that may cause pain.

关键词： Neonatal diabetes mellitus ABCC8 Sulfonylurea receptors 1 KATP channels Sulfonylurea Glyburide Insulinulin Case report

Impacts of high temperature,relative air humidity,and vapor pressure deficit on the seed set of contrasting maize genotypes during flowering

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Journal of Integrative Agriculture 2024年第9期23卷 2955-2969页

作者： Xin Dong Baole Li Zhenzhen Yan Ling Guan Shoubing huang Shujun Li Zhiyun Qi Ling Tang Honglin Tian Zhongjun fu hua yang Chongqing Academy of Agricultural Sciences Chongqing 401329China College of Agronomy and Biotechnology China Agricultural UniversityBeijing 100193China

Heat stress is a major constraint to current and future maize production at the global *** and female reproductive organs both play major roles in increasing seed set under heat stress at flowering,but their relative contributions to seed set are *** this study,a 2-year field experiment including three sowing dates in each year and 20 inbred lines was *** set,kernel number per ear,and grain yield were all reduced by more than 80%in the third sowing dates compared to the first sowing *** viability,silk emergence ratio,and anthesis-silking interval were the key determinants of seed set under heat stress;and their correlation coefficients were 0.89^(***),0.65^(***),and-0.72^(***),*** pressure deficit(VPD)and relative air humidity(RH)both had significant correlations with pollen viability and the silk emergence *** RH can alleviate the impacts of heat on maize seed set by maintaining high pollen viability and a high silk emergence *** a warming climate from 2020 to 2050,VPD will decrease due to the increased *** on their pollen viability and silk emergence ratios,the 20 genotypes fell into four different *** group with high pollen viability and a high silk emergence ratio performed better under heat stress,and their performance can be further improved by combining the improved flowering pattern traits.

关键词： maize pollen viability silk emergence heat stress relative humidity

Effect of Platelet-rich Plasma in Stimulating Macrophage Transformation into M2 Type under AMPK Signaling Pathway

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Chinese Journal of Biomedical Engineering 2024年第2期33卷 85-92页

作者： ZHONG Chang-rui fu Chun-hua Longyan First Affiliated Hospital of fujian Medical University The Second Hospital of Longyan

Objective: To explore the effect of platelet-rich plasma(RPR) in stimulating the transformation of pro-inflammatory(M1) macrophages into antiinflammatory(M2) under the adenosine-monophosphate-dependent protein kinase(AMPK) signaling pathway. Methods: Rat peritoneal macrophages(RAW264.7) were cultured and randomly divided into 8 groups: blank control group, LPS group, RPR group A, RPR group B, LPS+RPR(12 h) group, LPS+RPR(24 h) group A, LPS+RPR(24 h)group B, LPS+RPR(24 h) group C. RPR was prepared based on blood donors. The expressions of AMPK signaling pathway-related proteins(AMPK, ULK1, m TOR) and macrophage markers(i NOS, Arg-1) in the blank control group, LPS group, LPS+RPR(12 h)group and LPS+RPR(24 h) group were observed and compared. The expressions of macrophage markers in LPS+RPR(24 h) B and C groups were compared, and the expressions of AMPK and TGF-β in RPR A and B groups were compared. Results: The gray values of AMPK and ULK1 in LPS cells decreased significantly, while those in LPS+RPR(12 h) and LPS+RPR(24 h) A cells increased significantly. The gray values of AMPK and ULK1 in LPS+RPR(24 h) A cells were higher than those in LPS+RPR(12 h)cells(P<0.05). The m TOR gray value of LPS cells was significantly higher than that of LPS+RPR(24 h) A cells, and the m TOR gray value of LPS+RPR(24 h) A cells was significantly lower than that of LPS+RPR(12 h) cells(P<0.05). The expression of i NOS in LPS cells was significantly decreased, the expression of i NOS in LPS+RPR(12 h) and LPS+RPR(24 h) cells was significantly increased, and the expression of i NOS in LPS+RPR(24 h) cells was higher than that in LPS+RPR(12 h) cells(P<0.05). The expression of Arg-1 in LPS cells was significantly decreased, the expression of Arg-1 in LPS+RPR(12 h) and LPS+RPR(24 h) A cells was significantly increased, and the expression of Arg-1 in LPS+RPR(24 h) A cells was higher than that in LPS+RPR(12 h)cells(P<0.05). The i NOS expression level of LPS+PRP(24 h) C cells was significantly higher

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Comparison of prognosis and postoperative morbidities between standard pancreaticoduodenectomy and the TRIANGLE technique for resectable pancreatic ductal adenocarcinoma

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 689-699页

作者： He-Xing Hang Zheng-hua Cai Yi-Fei yang Xu fu Yu-Dong Qiu Hao Cheng Division of Pancreatic Surgery Department of General SurgeryNanjing Drum Tower HospitalThe Affiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008Jiangsu ProvinceChina

BACKGROUND Radical surgery combined with systemic chemotherapy offers the possibility of long-term survival or even cure for patients with pancreatic ductal adenocar-cinoma(PDAC),although tumor recurrence,especially locally,still inhibits the treatment *** TRIANGLE technique was introduced as an extended dissection procedure to improve the R0 resection rate of borderline resectable or locally advanced ***,there was a lack of studies concerning postoperative complications and long-term outcomes of this procedure on patients with resectable *** Patients with resectable PDAC eligible for PD from our hospital between June 2018 and December 2021 were enrolled in this retrospective cohort *** the patients were divided into PDstandard and PDTRIANGLE groups according to the surgical *** characteristics,surgical data,and postoperative morbidities were *** of the patients were followed up,and the date and location of tumor recurrence,and death were *** Kaplan-Meier method and log-rank test were used for the survival *** There were 93 patients included in the study and 37 underwent the TRIANGLE *** of operation was longer in the PDTRIANGLE group compared with the PDstandard group[440(410-480)min vs 320(265-427)min](P=0.001).Intraoperative blood loss[700(500-1200)mL vs 500(300-800)mL](P=0.009)and blood transfusion[975(0-1250)mL vs 400(0-800)mL](P=0.009)were higher in the PDTRIANGLE *** was a higher incidence of surgical site infection(43.2%vs 12.5%)(P=0.001)and postoperative diarrhea(54.1%vs 12.5%)(P=0.001)in the PDTRIANGLE *** rates of R0 resection and local recurrence,overall survival,and disease-free survival did not differ significantly between the two *** The TRIANGLE technique is safe,with acceptable postoperative morbidities compared with standardized PD,but it does not improve prognosis for patients with resectable PDAC.

关键词： Pancreatic ductal adenocarcinoma TRIANGLE technique Pancreaticoduodenectomy Prognosis Postoperative morbidities