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Automatic"Ground Truth"Annotation and Industrial Workpiece Dataset Generation for Deep Learning

International Journal of Automation and computing 2020年第4期17卷 539-550页

作者： fu-qiang liu Zong-Yi Wang College of Automation Harbin Engineering UniversityNo.145 Nantong RoadNangang DistrictHarbin 150001China

In industry,it is becoming common to detect and recognize industrial workpieces using deep learning *** this field,the lack of datasets is a big problem,and collecting and annotating datasets in this field is very labor *** researchers need to perform dataset annotation if a dataset is generated by *** is also one of the restrictive factors that the current method based on deep learning cannot expand *** present,there are very few workpiece datasets for industrial fields,and the existing datasets are generated from ideal workpiece computer aided design(CAD)models,for which few actual workpiece images were collected and *** propose an automatic industrial workpiece dataset generation method and an automatic ground truth annotation *** in our methods are three algorithms that we proposed:a point cloud based spatial plane segmentation algorithm to segment the workpieces in the real scene and to obtain the annotation information of the workpieces in the images captured in the real scene;a random multiple workpiece generation algorithm to generate abundant composition datasets with random rotation workpiece angles and positions;and a tangent vector based contour tracking and completion algorithm to get improved contour *** our procedures,annotation information can be obtained using the algorithms proposed in this *** completion of the annotation process,a json format file is *** R-CNN(Faster R-convolutional neural network),SSD(single shot multibox detector)and YOLO(you only look once:unified,real-time object detection)are trained using the datasets proposed in this *** experimental results show the effectiveness and integrity of this dataset generation and annotation method.

关键词： Deep learning dataset generation automatic annotation neural networks industrial workpiece dataset

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EFFECT OF HYPERCROSSLINKED RESINS SURFACE CHEMISTRY ON THE ADSORPTION OF PHENOL FROM AQUEOUS SOLUTION

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Chinese Journal of Polymer Science 2006年第6期24卷 585-591页

作者： Guan-hua Meng Ai-min Li Wei-ben Yang fu-qiang liu Quan-xing Zhang State Key Laboratory of Pollution Control and Resources Reuse School of the Environment Nanjing University Nanjing 210093 China Engineering Technology Research Center of Organic Toxie Substance Control and Resource Reuse of Jiangsu Province Nanjing 210038 China

Two hypercrosslinked resins with similar physical characters but different surface chemistry were synthesized and used to remove phenol from aqueous solutions. The FTIR spectra, elemental analysis and the Boehm titration were used to characterize the chemical properties of the resins. The adsorption experiments were carried out using the bottle-point technique, and the effects of the surface chemistry on the adsorption were discussed. The adsorption data fit well with the Freundlich model, indicating the heterogeneity of the resins surface. It could be seen from the experimental results that the adsorption capacity increased with the increase in the total surface concentration of oxygen-containing groups. The pH dependence and the effects of ionic strength were also discussed. The kinetic adsorption data fit well with the pseudo-second order model, and the results showed that the surface oxygen-containing groups have little effect on the adsorption rate.

关键词： Hypercrosslinked resin Phenol Surface chemistry Adsorption isotherm Kinetic study.

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Design, Synthesis and Anticancer Activity of Novel 6-（Aminophenyl）-2,4-bismorpholino-1,3,5-triazine Derivatives Bearing Arylmethylene Hydrazine Moiety

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Chemical Research in Chinese Universities 2014年第2期30卷 257-265页

作者： HUANG qiang fu qiangqiang liu Yajing BAI Jinying WANG Qianying LIAO Huimin GONG Ping Key Laboratory of Structure-Based Drug Design and Discovery Ministry of EducationShenyang Pharmaceutical University Shenyang 110016 P.R.China

In an attempt to develop potent and selective anticancer agents,we designed and synthesized a series of novel bis（morpholino-1,3,5-triazine） derivatives beating aylmethylene hydrazine moiety and evaluated their cytotoxicity,in vitro,against H460（non-small-cell lung cancer）,HT-29（human colorectal cancer） and MDA-MB-231（human breast cancer） cell *** pharmacological results indicate that all the compounds exhibit enhanced cytotoxicity than BMCL-200908069-1,and six target compounds（7e,7h,7j,9a,9b,9c） were superior to PAC-1 against all the tested cancer cell *** most active compound 7j,with IC50（inhibitory concentration 50％）values of 0.75,0.34 and 0.60 μ mol/L against HT-29,H460 and MDA-MB-231 cancer cell lines,was 39-,28-,and 60-fold more potent than BMCL-200908069-1 （29.24,9.52 and 36.21 μmol/L）,respectively.

关键词： Bis(morpholino-1,3,5-triazine) Design Anticancer activity

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Synergistic co-removal of zinc(Ⅱ) and cefazolin by a Fe/amine-modified chitosan composite

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Chinese Chemical Letters 2019年第12期30卷 2196-2200页

作者： Chen Ling Yixuan Zhao Zixi Ren Jiangang Han Changqing Zhu fu-qiang liu College of Biology and the Environment Nanjing Forestry UniversityNanjing 210037China State Key Laboratory of Pollution Control and Resource Reuse School of the EnvironmentNanjing UniversityNanjing 210023China

A novel Fe/amine modified chitosan composite(Fe/N-CS) was facilely synthesized and showed higher affinity to both Zn(Ⅱ) and cefazolin(CEF) than its *** co-adsorption of them by Fe/NCS was observed in varied *** adsorption amount maximally increased by 100.1% for Zn and68.2% for CEF in bi-solute *** initial adsorption rate of Zn(Ⅱ) also improved with *** increasing temperature facilitated *** results of the preloading tests,FTIR/XPS characterizations and DFT calculations suggested that(1) both polyamines and Fe sites participated in the adsorption of Zn(Ⅱ) and CEF,(2) Zn(Ⅱ) could serve as a new efficient site for CEF,forming [amineZn-CEF]/[FeOH-Zn-CEF] ternary complexes,and(3) the co-presence of CEF shielded the electrostatic repulsion between protonated amines and Zn(Ⅱ),contributing to the enhancement of Zn(Ⅱ) ***,the ion strength exerted positive and negative influences on the adsorption of Zn(Ⅱ) and CEF,***,CEF and Zn(Ⅱ) were successively recovered by 0.1 mol/L NaOH followed by2 mmol/L ***/N-CS could be stably reused five *** findings imply that Fe/N-CS is promising for the highly efficient co-removal of concurrent heavy metals and antibiotics.

关键词： Coadsorption Heavy metal ions Antibiotics Biomass Bridging effect Polyamine Hydrous ferric oxide

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Study on the Formation Mechanism of Oxygen-containing Groups on the Surfaces of Hypercrosslinked Polystyrenes

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Chinese Chemical Letters 2006年第1期17卷 121-124页

作者： Guan Hua MENG Ai Min LI Lin WU fu qiang liu Quan Xing ZHANG State Key Laboratory of Pollution Control and Resource Reuse School of the Environment Nanjing University Nanjing 210093 Engineering Technology Research-Center of Organic Toxic Substance Control and Resource Reuse of Jiangsu Province Nanjing 210038

The synthetic parameters were changed to explore the formation mechanism of the oxygen-containing groups on the surfaces of the hypercrosslinked polymers. The FT-IR spectra and the Boehm titration were used to characterize the surface chemistry of the synthesized polymers. The GC-MS was applied to analyze nitrobenzene which was the solvent in the reaction. The functionalities such as carbonyls and phenols were formed through the oxidation of residual chloromethyl groups by nitrobenzene and the carboxylic groups were formed through further oxidation by oxygen. The nitrobenzene was deoxidized to nitrosobenzene and further to aniline.

关键词： Synthesis oxygen-containing groups mechanism.

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Respiratory syncytial virus:the possible trigger of airway remodeling through matrix metaUoproteinase activation?

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Chinese Medical Journal 2007年第1期120卷 3-4页

作者： WEN fu-qiang liu Dai-shun Department of Respiratory Medicine West China Hospital WestChina School of Medicine Sichuan University Chengdu 610041China

Respiratory syncytial virus （RSV） is a leading cause of .epidemic respiratory tract illness in children. Severe RSV infections involving the lower respiratory tract are primarily seen in young children with naive immune systems and/or genetic predispositions. However, RSV was not recognized as a potentially serious problem in older adults until the 1970s, when outbreaks of the virus infection occurred in long-term care facilities. Since then, additional studies in hospitalized adults have suggested that RSV may be an important cause of illness in community-dwelling elderly people, patients with suppressed T-cell immunity （such as heart transplant recipients）.

关键词： respiratory syncytial virus matrix metalloproteinase airway remodeling

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Completion pneumonectomy An effective procedure to benign and malignant diseases of the residual lung

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吉林大学学报(医学版) 1997年第3期 69-73页

作者： Tong Li,Fan Zhimin,fu qiang,Meng Qingbin,liu Guojin ( Department of Surgical Oncology,First Clinical College ) \ \

回顾研究完结性全肺切除术。它是指手术切除从前经历过部分肺切除术后遗留下的残肺的一种手术。此种手术技术上困难，据文献报道，手术死亡率和并发症发生率均高于标准的全肺切除术。在过去的２３年里，先后有７５例病人，年龄从１５岁... 详细信息

回顾研究完结性全肺切除术。它是指手术切除从前经历过部分肺切除术后遗留下的残肺的一种手术。此种手术技术上困难，据文献报道，手术死亡率和并发症发生率均高于标准的全肺切除术。在过去的２３年里，先后有７５例病人，年龄从１５岁到７５岁，因再发原发癌（ｎ＝１５）、复发癌（ｎ＝３８）或良性胸膜肺疾病（ｎ＝２２），在我院和加拿大拉瓦尔医院接受完结性肺切除术。从首次手术到完结性全肺切除术的间隔，肺癌病人平均为２９个月，肺良性疾病平均为２１７个月。共有６例病人于术中（ｎ＝２）或术后早期（ｎ＝４）死亡。手术死亡率为８．０％，其中，肺癌病人手术死亡率为９．４％，肺良性疾病病人为４．５％。本病组例治疗结果提示，完全性全肺切除术手术危险性与标准全肺切除术所报道的相近，该手术值得推荐。

关键词： Completion pneumonectomy Residual lung Second primary cancer Local recurrence

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Synthesis,Structure and Properties of α-Keggin-type of K_(6)H_(3)[ZnW_(11)O_(40)Al]·9.5H_(2)O

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Chemical Research in Chinese Universities 1997年第4期13卷 14-18页

作者： YANG Qi hua, fu qiang, liu Jing fu ** (Department of Chemistry, Northeast Normal University, Changchun, 130024) XING Yan, LIN Yong hua and JIA Heng qing (Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022)

A new heteropolycomplex, K 6H 3[ZnW 11 O 40 Al]·9 5H 2O was prepared and characterized by means of elemental analysis, IR, UV spectroscopy, 27 Al NMR , electrochemistry and X ray crystallography. The crystal of K 6H 3[ZnW 11 O 40 Al]·9 5H 2O is cubic, space group Fm 3m , with lattice constants a=b=c =2 144 8(2) nm, V =9 866(2) nm 3, Mo radiation, R =0 057 8 for 497 independent data with [ I>2δ(I) ]. The anion is of α type Keggin structure with C s symmetry.

关键词： Lacunary Keggin structure Synthesis 27 Al NMR

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The emerging role of nitric oxide in the synaptic dysfunction of vascular dementia

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Neural Regeneration Research 2025年第2期20卷 402-415页

作者： Xiaorong Zhang Zhiying Chen Yinyi Xiong Qin Zhou Ling-qiang Zhu Dan liu Department of Pathology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Jiujiang Clinical Precision Medicine Research Center JiujiangJiangxi ProvinceChina Center for Cognitive Science and Transdisciplinary Studies Jiujiang UniversityJiangxi ProvinceChina Department of Neurology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of Rehabilitation Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of Pathophysiology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

With an increase in global aging,the number of people affected by cerebrovascular diseases is also increasing,and the incidence of vascular dementia-closely related to cerebrovascular risk-is increasing at an epidemic ***,few therapeutic options exist that can markedly improve the cognitive impairment and prognosis of vascular dementia *** in Alzheimer’s disease and other neurological disorders,synaptic dysfunction is recognized as the main reason for cognitive *** oxide is one of the ubiquitous gaseous cellular messengers involved in multiple physiological and pathological processes of the central nervous ***,nitric oxide has been implicated in regulating synaptic plasticity and plays an important role in the pathogenesis of vascular *** review introduces in detail the emerging role of nitric oxide in physiological and pathological states of vascular dementia and summarizes the diverse effects of nitric oxide on different aspects of synaptic dysfunction,neuroinflammation,oxidative stress,and blood-brain barrier dysfunction that underlie the progress of vascular ***,we propose that targeting the nitric oxide-sGC-cGMP pathway using certain specific approaches may provide a novel therapeutic strategy for vascular dementia.

关键词： endoplasmic reticulum stress endothelial nitric oxide synthase gene therapy nitric oxide NO-sGC-cGMP pathway synaptic dysfunction vascular dementia

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次氯酸与Cu2+氧化修饰高密度脂蛋白

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生物化学与生物物理学报 2001年第3期33卷 262-268页

作者：傅强刘秉文华西医科大学生物化学与分子生物学研究所!成都610041

为了进一步研究氧化修饰高密度脂蛋白 (Ox HDL)的性质 ,观察了次氯酸 (HOCl)及Cu2 +对HDL的氧化作用 ,并对其性质进行了研究。结果发现 ,同LDL一样 ,HDL在体外也可被HOCl及Cu2 +氧化修饰 ,使其颗粒表面负电荷增加 ,TBARS值上升 ;另外 ,... 详细信息

为了进一步研究氧化修饰高密度脂蛋白 (Ox HDL)的性质 ,观察了次氯酸 (HOCl)及Cu2 +对HDL的氧化作用 ,并对其性质进行了研究。结果发现 ,同LDL一样 ,HDL在体外也可被HOCl及Cu2 +氧化修饰 ,使其颗粒表面负电荷增加 ,TBARS值上升 ;另外 ,在HOCl氧化修饰下 ,HDL的载脂蛋白AI及AII发生降解 ,而在Cu2 +氧化下 ,HDLapoAI则聚合为二聚体 ;HOCl和Cu2 +诱导下Ox HDL卵磷脂降解成溶血卵磷脂 ,同时其载脂蛋白还发生羰基修饰。然而HOCl和Cu2 +介导的HDL氧化修饰在性质及动力学改变上各不相同

关键词：高密度脂蛋白次氯酸 Cu2+ 氧化修饰 Ox-HDL

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