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World Journal of Clinical Cases 2021年第30期9卷 9192-9197页

作者： Xin Yao Shi-Hui Li Li-Rong fu Shan-Hong Tang jian-Ping qin Department of Gastroenterology General Hospital of Western Theater CommandChengdu 610083Sichuan ProvinceChina

BACKGROUND Esophagogastric varices are a common complication of cirrhosis with portal hypertension and endoscopic treatment has been recognized as a primary preventive and therapeutic option for such patients;however,it should be noted that bradyarrhythmia is regarded as one of the contraindications to endoscopic ***,acute variceal bleeding may result in a high mortality rate in cirrhotic patients with portal hypertension accompanied by *** present,there is an absence of reports concerning the treatment of such group of patients who underwent transjugular intrahepatic portosystemic shunt(TIPS).The present report details the case of a cirrhotic patient with acute variceal bleeding accompanied by bradyarrhythmia who underwent TIPS under temporary pacemaker *** SUMMARY We report the case of a 64-year-old male patient who was confirmed with bradyarrhythmia by ambulatory electrocardiogram 24 h before the *** patient was successfully treated by TIPS under temporary pacemaker *** In terms of cirrhotic patients with abnormal cardiac electrophysiological conduction,TIPS may be effective in reducing the complications of portal hypertension following the exclusion of severe pulmonary hypertension and heart failure,showing moderate feasibility in clinical applications.

关键词： Transjugular intrahepatic portosystemic shunt Hypertension Cirrhotic Temporary pacemaker Bradyarrhythmia

Simulation of the Brownian coagulation of nanoparticles with initial bimodal size distribution via moment method

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Acta Mechanica Sinica 2012年第5期28卷 1227-1237页

作者： jian-Zhong Lin fu-Jun Gan China Jiliang University Department of Mechanics Zhejiang University

The Brownian coagulation of nanoparticles with initial bimodal size distribution, i.e., mode i and j, is numerically studied using the moment method. Evolutions of particle number concentration, geometric average diameter and geometric standard deviation are given in the free molecular regime, the continuum regime, the free molecular regime and transition regime, the free molecular regime and continuum regime, respectively. The results show that, both in the free molecular regime and the continuum regime, the num- ber concentration of mode i and j decreases with increasing time. The evolutions of particle geometric average diameter with different initial size distribution are quite different. Both intra-modal and inter-modal coagulation finally make the polydispersed size distribution become monodispersed. As time goes by, the size distribution with initial bimodal turns to be unimoda/and shifts to a larger particle size range. In the free molecular regime and transition regime, the inter- modal coagulation becomes dominant when the number concentrations of mode i and j are of the same order. The effects of the number concentration of mode i and mode j on the evolution of geometric average diameter of mode j are negligible, while the effects of the number concentration of mode j on the evolution of geometric average diameter of mode j is distinct. In the free molecular regime and continuum regime, the higher the initial number concentration of mode j, the more obvious the variation of the number concentration of mode i.

关键词： Nanoparticles - Brownian coagulation. Bimodalsize distribution Moment method

Magnaporthe oryzae MTP1 gene encodes a type Ⅲ transmembrane protein involved in conidiation and conidial germination

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第7期9卷 511-519页

作者： qin LU jian-ping LU Xiao-dong LI Xiao-hong LIU Hang MIN fu-cheng LIN College of Life Sciences Zhejiang University Hangzhou 310058 China Institute of Biotechnology Zhejiang University Hangzhou 310029 China

In this study the MTP1 gene, encoding a type III integral transmembrane protein, was isolated from the rice blast fungus Magnaporthe oryzae. The Mtp 1 protein is 520 amino acids long and is comparable to the Ytp 1 protein of Saccharomyces cerevisiae with 46% sequence similarity. Prediction programs and MTP1-GFP （green fluorescent protein） fusion expression results indicate that Mtp 1 is a protein located at several membranes in the cytoplasm. The functions of the MTP1 gene in the growth and development of the fungus were studied using an MTP1 gene knockout mutant. The MTP1 gene was primarily expressed at the hyphal and conidial stages and is necessary for conidiation and conidial germination, but is not required for pathogenicity. The Amtpl mutant grew more efficiently than the wild type strain on non-fermentable carbon sources, implying that the MTP1 gene has a unique role in respiratory growth and carbon source use.

关键词： Magnaporthe oryzae Magnaporthe grisea MTP1 cDNA Gene knockout Conidial germination

Radiation effect of Apocynum fiber

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Nuclear Science and Techniques 2006年第1期17卷 38-42页

作者： ZOU qin ZHAO Xin ZHANG jian-Bing TANG Jun FAN Zhao-Tian SUN Wan-fu The Center of Analysis and Measurement of Xinjiang University Urumqi 830046 China

Changes of surface shape, aggregate state, and microstructure of Apocynum fiber before and after irradia-tion were studied by XRD, IR, SEM, ESR, and solid state 13C CP/ MAS NMR. The results show that the surface shape and microstructure were not spoiled under 50 kGy gamma irradiation, while the crystallization of Apocynum fiber changed under 280 kGy . It also shows that different free radicals appear after irradiation and their concentration increases with the increase of irradiation dose.

关键词：辐射效应罗布麻纤维氢键结合表面形状微结构

An improved de-interleaving algorithm of radar pulses based on SOFM with self-adaptive network topology

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Journal of Systems Engineering and Electronics 2020年第4期31卷 712-721页

作者： jianG Wen fu Xiongjun CHANG Jiayun qin Rui School of Information and Electronics Beijing Institute of TechnologyBeijing 100081China

As a core part of the electronic warfare(EW) system,de-interleaving is used to separate interleaved radar signals. As interleaved radar pulses become more complex and denser, intelligent classification of radar signals has become very important. The self-organizing feature map(SOFM) is an excellent artificial neural network, which has huge advantages in intelligent classification of complex data. However, the de-interleaving process based on SOFM is faced with the problems that the initialization of the map size relies on prior information and the network topology cannot be adaptively adjusted. In this paper, an SOFM with self-adaptive network topology(SANT-SOFM) algorithm is proposed to solve the above problems. The SANT-SOFM algorithm first proposes an adaptive proliferation algorithm to adjust the map size, so that the initialization of the map size is no longer dependent on prior information but is gradually adjusted with the input data. Then,structural optimization algorithms are proposed to gradually optimize the topology of the SOFM network in the iterative process,constructing an optimal SANT. Finally, the optimized SOFM network is used for de-interleaving radar signals. Simulation results show that SANT-SOFM could get excellent performance in complex EW environments and the probability of getting the optimal map size is over 95% in the absence of priori information.

关键词： de-interleaving self-organizing feature map(SOFM) self-adaptive network topology(SANT)

Division of diagenesis reservoir facies and its control——Case study of Chang-3 reservoir in Yangchang formation of fuxian exploration area in northern Shaanxi

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Mining Science and Technology 2009年第4期19卷 537-543页

作者： fu Guo-min qin Xiao-li MIAO qing ZHANG Tian-jin YANG jian-peng lnstitute of Resources Chang ＇an University Xi＂ an Shaanxi 710054 China Zhongyuan Oil Field Company Sinopec Puyang Henan 457001 China Department of Geology and Environment Engineering Xi＇ an University of Science and Technology Xi＇ an Shaanxi 710054 China yanchang Oilfield Limited-Liability Company Yan ＇an Shaanxi 716000 China

By dividing the diagenetic reservoir facies and studying its distribution,we can effectively evaluate *** an analytical method for mutual relationships among diagenesis of reservoirs,structural characteristics and the origin of types of sand,we classified the diagenetic reservoir of the Yanchang formation Chang-3 oil layer into different types and analyzed the factors controlling this high quality *** results show that:1) the catagenesis of the Chang-3 oil layer in the fuxian region is complex and variable;2) mechanical compaction,pressure solutions and cementation of all kinds of authogenous minerals decreases porosity by 28.13% and 3) corrosion increases porosity by 3.39%.Cementation and corrosion of laumontite is a kind of catagenesis which makes this region different from other exploratory *** original amount and rate of corrosion of laumontite are the main factors for the increase in laumontite *** Chang-3 oil layer developed four kinds of diagenetic reservoir facies,of which the weak compaction facies,i.e.,laumontite corrosion and overgrowth,of the original pore reservoir facies has the most promising *** distribution is controlled by a sedimentary facies zone and is widely developed in the original truncated tributary channel facies belt of the delta *** development of this high quality reservoir is controlled by the distribution of sedimentary sand bodies and secondarily-eroded porosity of laumontite in the Chang-3 oil layer of the fuxian exploratory region.

关键词： diagenesis laumontite diagenetic facies Yanchang formation northern Shaanxi province

Role of CD8^(+) T lymphocyte cells:Interplay with stromal cells in tumor microenvironment

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Acta Pharmaceutica Sinica B 2021年第6期11卷 1365-1378页

作者： qin Xie jian Ding Yi Chen College of Pharmaceutical Sciences Zhejiang UniversityHangZhou 310012China Division of Anti-Tumor Pharmacology Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beiing 100049China State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Shanghai Hai He Pharmaceutical Co. Ltd.Shanghai 201203China

CD8^(+) T lymphocytes are pivotal cells in the host response to antitumor *** microenvironments provide the conditions necessary for regulating infiltrating CD8^(+) T cells in favor of tumor survival,including weakening CD8^(+) T cell activation,driving tumor cells to impair immune attack,and recruiting other cells to reprogram the immune *** in tumor microenvironment,stromal cells exert immunosuppressive skills to avoid CD8^(+) T cell *** this review,we explore the universal function and fate decision of infiltrated CD8^(+) T cells and highlight their antitumor response within various stromal architectures in the process of confronting neoantigen-specific tumor ***,this review provides a foundation for the development of antitumor therapy based on CD8^(+)T lymphocyte manipulation.

关键词： CD8+T lymphocyte Stromal cell Tumor microenvironment Immunosuppression Immunotherapy Antitumor

On entire solutions of some Fermat type differential-difference equations

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 69-88页

作者： LONG jian-ren qin Da-zhuan School of Mathematical Sciences Guizhou Normal UniversityGuiyang 550025China

On one hand,we study the existence of transcendental entire solutions with finite order of the Fermat type difference *** the other hand,we also investigate the existence and growth of solutions of nonlinear different... 详细信息

关键词： entire solutions differential-difference equations existence finite order

Dependence of Charged Particle Pseudorapidity Distributions on Centrality in Pb-Pb Collisions at√sNN=2.76 TeV

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Chinese Physics Letters 2013年第2期30卷 61-64页

作者： SUN jian-Xin TIAN Cai-Xing WANG Er-qin LIU fu-Hu Institute of Theoretical Physics Shanxi UniversityTaiyuan 030006 School of Physics and Electronic Science Datong UniversityDatong 037009

The dependence of charged particle pseudorapidity distributions on centrality in Pb-Pb collisions at√sNN=2.76 TeV is studied by using a multi-source thermal model(previously the two-cylinder model or the multi-source ideal gas model).The rapidity shifts of the interacting system are almost independent of the centrality *** contribution of leading nucleons increases with the increasing centrality class(percent).The calculated results are compared and found to be in agreement with the experimental data of the ATLAS,ALICE,and CMS collaborations.

关键词： N=2 cylinder Collisions

Experimental study of the shrinkage behavior of cemented paste backfill

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Journal of Rock Mechanics and Geotechnical Engineering 2021年第3期13卷 545-554页

作者： Jiahao qin jian Zheng Li Li Research Institute on Mines and the Environment(RIME UQAT-Polytechnique) Department of CivilGeological and Mining EngineeringÉcole Polytechnique de MontréalMontréalQuébecH3C 3A7Canada

Cemented paste backfill(CPB)is largely used in underground mine stopes *** a CPB is placed in a stope,an important task is to estimate the settlement associated with the shrinkage and selfweight consolidation of the *** is closely related to the volume management to ensure the stability of barricades and tight contacts between the backfill and stope *** the years,shrinkage studies were mostly performed on fine-grained soils(silts and clays),with only a few publications on the shrinkage behavior of uncemented *** study has been published on the shrinkage behavior of *** fill this gap,a series of shrinkage tests has been conducted on CPB with different cement contents,including zero cement content(uncemented paste backfill,uCPB).The results show that the shrinkage response of CPB is very different from that of *** a given initial water content,CPB exhibits a shorter normal shrinkage stage than *** unsaturation onset water content and void ratio,shrinkage limit and final void ratio of CPB are generally higher than those of *** a given cement content,the shrinkage behaviors of CPB and uCPB are significantly influenced by the initial water content.

关键词： Cemented paste backfill(CPB) Shrinkage Evaporation Underground mine stopes Volume variation