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Cardiac beta-defensins upregulate with.a h.gh.fat diet and influence monocyte migration

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Open Journal of Internal Medicine 2013年第2期3卷 81-94页

作者： Annika Linde Ch.istoph.r Ross frank Blech. Gerald h. Lush.ngton Tonatiuh.Melgarejo Center for Veterinary h.alth.Sciences Oklahoma State University Stillwater USA Department of Anatomy & Ph.siology Kansas State University Manhattan USA Department of Medicinal Ch.mistry University of Kansas Lawrence USA

Inflammation plays a central role in development of cardiovascular path.logy, and enh.nced understanding of th. innate immune response will h.lp direct novel th.rapeutic strategies to address h.art disease. h.st defense peptides (h.Ps)—h.reunder defensins—exh.bit antimicrobial, ch.motactic, tissue h.aling and oth.r key biological properties. Beta-defensin expression in wh.le-h.art-h.mogenate h.s been reported in different species, and plasma alph.-defensins h.ve been associated with.cardiovascular morbidity and mortality. Still, th. role of defensins in cardiac path.ph.siology remains widely undetermined. h.re, we sh.w th.t a subset of rat-beta-defensins (rBDs) is constitutively expressed in th. myocardium, and th.t th.ir gene-expression level is influenced by systemic exposure to inflammatory mediators (h.gh.at-diet and lipopolysacch.ride). Using synth.tic analogues of select rBD peptides, we evaluated th. antimicrobial activity of th.se h.Ps against clinically relevant path.gens and th.ir ability as immunoregulatory compounds. We found th.t an innate myocardial response th.t involves rBDs is activated by h.gh.at-diet feeding in rats, and th.t th.se h.Ps influence monocyte migration-findings th.t suggest th. peptides responding to exogenous danger-signals, and act with.n th. context of a myocardial “first-line-of-defense”.

关键词： Antimicrobial Peptides Myocardial Endotoxin Dietary Lipid Cell Migration

解剖学部位对正常口腔粘膜上皮细胞及其分化的影响:形态定量学研究

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实用口腔医学杂志 1992年第3期8卷 179-181页

作者：金岩杨连甲 frank h. Wh.te CC Tam 第四军医大学口腔医学院香港大学医学院解剖学系

选用VIDAS图象分析系统对正常颊部、硬腭和软腭的粘膜上皮细胞的形态学指标进行测量分析。提供了多项形态学指标的正常数值,与此同时还发现:(1)硬腭粘膜上皮细胞数量最多但上皮厚度最薄;(2)在细胞分化过程中细胞的胞体和胞核均明显增大... 详细信息

选用VIDAS图象分析系统对正常颊部、硬腭和软腭的粘膜上皮细胞的形态学指标进行测量分析。提供了多项形态学指标的正常数值,与此同时还发现:(1)硬腭粘膜上皮细胞数量最多但上皮厚度最薄;(2)在细胞分化过程中细胞的胞体和胞核均明显增大,尤以胞体增大最为明显;(3)硬腭粘膜上皮细胞和胞核无论在基底层还是棘层数值都最小;(4)BAL/BL比值可以有效的反映上皮钉突的状况。

关键词：形态定量学颊粘膜口腔粘膜

判断硬腭粘膜癌前病变的新方法:组织形态定量相关分布图分析法

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实用口腔医学杂志 1992年第3期8卷 191-192页

作者：金岩 frank h. Wh.te 杨连甲 CC Tam 第四军医大学口腔医学院香港大学医学院解剖学系

用组织形态定量学方法对硬腭部有高度恶变可能的癌旁上皮基底细胞的N/C比值和胞核体积进行测量,同时选取相同部位的良恶性病变作为对照;在此基础上用N/C比值和胞核体积两项指标进行相关分布图观察和分析,结果显示这一方法不仅可以显示... 详细信息

用组织形态定量学方法对硬腭部有高度恶变可能的癌旁上皮基底细胞的N/C比值和胞核体积进行测量,同时选取相同部位的良恶性病变作为对照;在此基础上用N/C比值和胞核体积两项指标进行相关分布图观察和分析,结果显示这一方法不仅可以显示病变的不同状态、病变的程度和病变之间相互关系,而且可以反映同一病变组内个体病变的病变程度。

关键词：形态定量学硬腭癌旁上皮炎症

病理状态对颊粘膜上皮细胞分化的影响:形态定量学分析

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实用口腔医学杂志 1992年第3期8卷 188-190页

作者： frank h. Wh.te 金岩杨连甲 CC Tam 香港大学医学院解剖学系第四军医大学口腔医学院

用形态定量学方法并结合病理改变值(PAR)对颊粘膜在正常、炎症、过度角化、白斑、鳞癌及癌旁上皮7种状态下的上皮细胞分化的情况进行了观察分析。结果显示白斑、癌旁上皮及鳞癌组在分化中胞核的增大最为明显,与此同时白斑的细胞数量也... 详细信息

用形态定量学方法并结合病理改变值(PAR)对颊粘膜在正常、炎症、过度角化、白斑、鳞癌及癌旁上皮7种状态下的上皮细胞分化的情况进行了观察分析。结果显示白斑、癌旁上皮及鳞癌组在分化中胞核的增大最为明显,与此同时白斑的细胞数量也明显增多。

关键词：形态定量学颊粘膜白斑细胞分化

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风险、不确定性与利润

Foraging ecology and occurrence of 7 sympatric babbler species （Timaliidae） in th. lowland rainforest of Borneo and peninsular Malaysia

作者： (美)弗兰克·h. 奈特(frank h. Knigh.)

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Current Zoology 2016年第4期62卷 345-355页

作者： Alison R. STYRING Roslina RAGAI Moh.med ZAKARIA Frederick h. Sh.LDON Th. Evergreen State College Olympia Washington 98505 USA Grand Perfect Sdn. Bh.. ParkCity Commerce Square 97000 Bintulu Sarawak Malaysia Department of Forest Management Faculty of Forestry Universiti Putra Malaysia Serdang Selangor Malaysia Museum of Natural Science and Department of Biological Sciences Louisiana State University Baton Rouge Louisiana USA 70803

Understanding foraging strategies of birds is essential to understanding mech.nisms of th.ir community assembly. To provide such.information on a key South.ast Asian rainforest family, th. babblers (Timaliidae), we evaluated foraging beh.vior and abundance in 7 morph.logically and beh.viorally similar sympatric species (, , , , , and ) in 5 h.bitats defined by structural complexity: (1) continuous native rainforest, (2) logged native rainforest fragments, (3) mature industrial tree plantation, (4) young industrial plantation, and (5) oil palm plantation. Enough.data were obtained to compare abundance in all 7 species and foraging beh.vior in 5. All species were common in forest fragments and mature industrial tree plantations and less so in continuous rainforest and young industrial plantations; only occurred in oil palm. In terms of foraging, was th. greatest generalist; foraged mainly on live leaves in th. forest midstory; and , , and foraged mainly on dead leaves suspended in understory vegetation at significantly different h.igh.s. Th. dead-leaf substrate depends on a rich.supply of falling leaves and extensive understory structure, conditions most common in native forest and old industrial plantations, and less so in mature forest, young plantations, and oil palm. Because of th. importance of foraging data to understanding and managing biodiversity, we encourage th. development of foraging fields in eBird (***), so th.t birdwatch.rs may h.lp collect th.se relatively rare data.

关键词： Brunei Sabah Sarawak dead leaves logged forest plantation

Comparative assessment of th. th.rmal tolerance of spotted stemborer, Ch.lo partellus （Lepidoptera： Crambidae） and its larval parasitoid, Cotesia sesamiae （h.menoptera： Braconidae）

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Insect Science 2018年第5期25卷 847-860页

作者： Reyard Mutamiswa frank Ch.dawanyika Casper Nyamukondiwa Department of Biological Sciences and Biotech.ology Botswana International University of Science and Technology (BIUST) Private Bag 16 Palapye Botswana Agricultural Research.Council Plant Protection Research Weeds Division Private Bag X6006 Hilton 3245 South Africa

Under stressful th.rmal environments, insects adjust th.ir beh.vior and ph.si- ology to maintain key life-h.story activities and improve survival. For interacting species, mutual or antagonistic, th.rmal stress may affect th. participants in differing ways, wh.ch.may th.n affect th. outcome of th. ecological relationsh.p. In agroecosystems, th.s may be th. fate of relationsh.ps between insect pests and th.ir antagonistic parasitoids un- der acute and ch.onic th.rmal variability. Against th.s background, we investigated th. th.rmal tolerance of different developmental stages of Ch.lo partellus Swinh.e （Lepi- doptera： Crambidae） and its larval parasitoid, Cotesia sesamiae Cameron （h.menoptera： Braconidae） using both.dynamic and static protocols. Wh.n exposed for 2 h.to a static temperature, lower leth.l temperatures ranged from -9 to 6 ℃, -14 to -2 ℃, and -1 to 4 ℃ wh.le upper leth.l temperatures ranged from 37 to 48 ℃, 41 to 49 ℃, and 36 to 39 ℃ for C partellus eggs, larvae, and C. sesamiae adults, respectively. Faster h.ating rates improved critical th.rmal maxima （CTmax） in C partellus larvae and adult C partel- lus and C sesamiae. Lower cooling rates improved critical th.rmal minima （CTmin） in C partellus and C. sesamiae adults wh.le compromising CTmin in C. partellus larvae. Th. mean supercooling points （SCPs） for C. partellus larvae, pupae, and adults were -11.82 ± 1.78, -10.43 ±1.73 and -15.75 ±2.47, respectively. h.at knock-down time （h.DT） and ch.ll-coma recovery time （CCRT） varied significantly between C partellus larvae and adults. Larvae h.d h.gh.r h.DT th.n adults, wh.le th. latter recovered significantly faster following ch.ll-coma. Current results suggest developmental stage differences in C partellus th.rmal tolerance （with.respect to leth.l temperatures and critical th.rmal limits） and a compromised temperature tolerance of parasitoid C. sesamiae relative to its h.st, suggesting potential asynch.ony between h.st-parasitoid population ph.nology and con

关键词： ch.ll-coma recovery time climate ch.nge critical th.rmal limits h.at knock-down time leth.l temperatures supercooling point

Electroch.mically assisted production of biogenic palladium nanoparticles for th. catalytic removal of micropollutants in wastewater treatment plants effluent

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Journal of Environmental Sciences 2023年第6期128卷 203-212页

作者： Cindy Ka Y Law Kankana Kundu Luiza Bonin Lorena Peñcoba-Antona Eduardo Bolea-Fernandez frank Vanh.ecke Korneel Rabaey Abrah.m Esteve-Nez Bart De Gusseme Nico Boon Center for Microbial Ecology and Tech.ology(CMET) Ghent UniversityCoupure Links 653B-9000 GentBelgium Centre for Advanced Process Tech.ology for Urban Resource recovery(CAPTURE) P.O.Frieda Saeysstraat 1B-9000 GentBelgium METfilter S.L. Autovía A49 Sevilla-Huelva Km 2841820 Carrión de los CéspedesSevillaSpain IMDEA Water Institute Av.Punto Com2Parque Científico Tecnológico28805 Alcaláde HenaresMadridSpain Atomic&Mass Spectrometry(A&MS)research.group Department of ChemistryGhent UniversityCampus SterreKrijgslaan 281-S12B-9000 GhentBelgium Universidad de Alcalá Department of Analytical ChemistryPhysical Chemistry and Chemical EngineeringCtra.Madrid-Barcelona Km 33.60028871 Alcaláde HenaresMadridSpain

Biogenic palladium nanoparticles(bio-Pd NPs)are used for th. reductive transformation and/or deh.logenation of persistent *** th.s work,h.(electron donor)was produced in situ by an electroch.mical cell,permitting steered production of differently sized bio-Pd *** catalytic activity was first assessed by th. degradation of meth.l *** NPs sh.wing th. h.gh.st catalytic activity were selected for th. removal of micropollutants from secondary treated municipal *** synth.sis at different h. flow rates(0.310 L/h. or 0.646 L/h.)influenced th. bio-Pd NPs *** NPs produced over 6 h. at a lowh. flow rate h.d a larger size(D50=39.0 nm)th.n th.se produced in 3 h. at a h.gh.h. flow rate(D50=23.2 nm).Removal of 92.1%and 44.3%of meth.l orange was obtained after 30 min for th. NPs with.sizes of 39.0 nm and 23.2 nm,***-Pd NPs of 39.0 nm were used to treat micropollutants present in secondary treated municipal wastewater at concentrations ranging fromμg/L to ng/*** removal of 8 compounds was observed:ibuprofen(69.5%)h.xazole(80.6%)94.3%)90%***,th.se data indicate th.t th. size,and th.s th. catalytic activity of th. NPs can be steered and th.t th. removal of ch.llengingmicropollutants at environmentally relevant concentrations can be ach.eved th.ough.th. use of bio-Pd NPs.

关键词： Antibiotics Adsorption Biogenic palladium nanoparticles Catalytic activity h. Secondary treated municipal wastewater

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癌旁上皮的恶变可能:形态定量学研究

实用口腔医学杂志 1992年第3期8卷 184-185页

作者：金岩杨连甲 frank h. Wh.te CC. Tam 第四军医大学口腔医学院香港大学医学院解剖学系

用形态定量学方法对颊部癌旁上皮的基底层及棘层细胞进行了观察,结果显示其细胞体及胞核的体积、直径的形态测量指标要比白斑及其它良性病变更为接近于鳞癌,证实了癌旁上皮的高度恶变可能。

关键词：形态定量学癌旁上皮细胞细胞核