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Primary Hyperparathyroidism Revealed by Impaired Renal Function with Persistent Elevation of Parathormon (PTH) and Normal Calcemia after Surgical Removal of the Parathyroid Adenoma

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Open Journal of Endocrine and Metabolic Diseases 2023年第2期13卷 39-44页

作者： Yao Assita Lecadou Jocelyne Maman Salahoudine N’guessan Anselme Danho Jocelyne kouassi frank Hué Adélaïde Koffi Dago Pierre Abodo Jacko Endocrinology Diabetology Department CHU Yopougon Abidjan Ivory Coast

Introduction: The curative management of primary hyperparathyroidism is based on surgery. We report the case of a patient presenting with elevated parathormone despite surgical removal of the parathyroid adenoma. Observation: A 48-year-old patient presented for more than 6 months with significant weight loss, polyuria with polydipsia and impaired renal function. The assessment carried out revealed hypercalcaemia at 155 mg/L with hypophastetaemia at 24 mg/L and an elevation of the parathyroid hormone at 218.9 pg/ml. Cervical ultrasound showed a mass at the expense of the lower left parathyroid gland. These results made it possible to conclude primary hyperparathyroidism by parathyroid adenoma which was supported surgically. The postoperative biological assessment revealed a normocalcemia at 85 mg/L associated with an increase in parathormone (PTH) at 271.9 pg/ml. In front of the normalization of calcemia in the subsequent controls and the amendment of all the signs, monitoring was carried out. 9 months after surgery, spontaneous normalization of PTH was observed at 38.4 pg/ml with normal serum calcium at 90 mg/l. Discussion: Primary hyperparathyroidism can be revealed by other manifestations. Post-operative follow-up is generally simple with normalization of PTH and serum calcium. However, there may persist an elevation of PTH with normal self-limiting calcemia.

关键词： Primary Hyperparathyroidism Postoperative Follow-Up Normocalcemic Hyperparathormonemia

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Glycemic Responses of Food Formulations Based on White Rice and White Bean

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Food and Nutrition Sciences 2023年第3期14卷 225-232页

作者： Assita Yao Jean-Brice Gbakayoro Cyrille Tan Anselme N’guessan Jocelyne Danho frank kouassi Adélaïde Hué Pierre Koffi-Dago Mory Traoré Salahoudine Maman Jacko Abodo Albarin Gbogouri Service d’Endocrinologie Diabétologie du CHU de Yopougon Abidjan Côte d’Ivoire Laboratoire de Nutrition et Sécurité Alimentaire Université Nangui Abrogoua Abidjan Côte d’Ivoire

The management of diabetes mellitus is based on lifestyle and dietary measures suggesting the consumption of foods with a low glycemic index. The present study was conducted in order to propose food formulas based on white rice and white beans resulting in a lower glycemic response. For this, food formulations based on these foods were first made, in particular the formulation [75% white rice + 25% white beans] and the formulation [50% rice + 50% white beans]. Then, the biochemical composition of white rice, white bean and these two formulations was determined by the usual methods. Finally, their glycemic responses over 120 minutes were studied by the FAO/ WHO 1998 method. The results showed that white rice [100% white rice] had the highest carbohydrate content (54.61%) followed respectively by the formulation [75% white rice + 25% white bean] (45.69%), the white bean [100% white bean] (29.1%) and the formulation [50% white rice + 50% white bean] (26.16%). In terms of glycemic responses, the formulation [50% white rice + 50% white beans] presented the best evolution with a lower peak (6.041 mmol/L) observed at T45min and a lower postprandial glycemia (4.872 mmol/ L) at T120min. An increase in the proportion of beans is therefore recommended as it may suggest a beneficial metabolic effect.

关键词： White Rice White Bean Food Formulation Glycemic Response

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