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Acupuncture for the management of dry eye disease

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Frontiers of Medicine 2022年第6期16卷 975-983页

作者： Julia Prinz Nicola Maffulli Matthias Fuest Peter Walter frank Hildebrand Filippo Migliorini Department of Ophthalmology RWTH Aachen UniversityPauwelsstr.3052074AachenGermany Department of Medicine Surgery and DentistryUniversity of SalernoVia S.Allende84081BaronissiSAItaly Queen Mary University of London Barts and the London School of Medicine and DentistryMile End Hospital275 Bancroft RoadLondonEI 4DGEngland School of Pharmacy and Bioengineering Keele University Faculty of MedicineThornburrow DriveStoke on TrentEngland Department of Orthopedics University Clinic AachenRWTH Aachen University Clinic52064AachenGermany

The effectiveness of using acupuncture for dry eye disease(DED)is ***,this systematic review investigated the effectiveness and feasibility of using acupuncture for DED in accordance with the 2020 PRISMA *** outcomes of interests were(1)to evaluate the efficacy of acupuncture in improving the ocular surface disease index(OSDI),Schirmer I test score,and tear breakup time from baseline to the last follow-up;(2)to determine possible complications of using acupuncture;and(3)to investigate the superiority of acupuncture over other commonly used treatments for *** from 394 patients were *** showed that acupuncture significantly prolonged the tear breakup time(P<0.0001),significantly increased the Schirmer I test score(P<0.0001),and significantly reduced the OSDI(P<0.0001)from baseline to the last *** with the control group,the acupuncture group had significantly greater Schirmer I test score(P<0.0001),significantly longer tear breakup time(P=0.0004),and significantly lower OSDI(P=0.002).These results suggest that acupuncture is effective and feasible in improving symptoms and signs of *** severe adverse effects of acupuncture were observed.

关键词： dry eye disease xerophthalmus acupuncture

Enhancement of THz generation in LiNbO_(3) waveguides via multi-bounce velocity matching

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Light(Science & Applications) 2022年第12期11卷 2994-3001页

作者： Blake S.Dastrup Eric R.Sung frank Wulf Clara Saraceno Keith A.Nelson Department of Chemistry Massachusetts Institute of TechnologyCambridgeMA 02139USA Faculty of Electrical Engineering and Information Technology Ruhr University BochumBochum 44801Germany

To realize the full promise of terahertz polaritonics(waveguide-based terahertz field generation,interaction,and readout)as a viable spectroscopy platform,much stronger terahertz fields are needed to enable nonlinear and even robust linear terahertz *** use a novel geometric approach in which the optical pump is totally internally reflected to increase the distance over which optical rectification *** matching is achieved by tuning the angle of internal *** doing this,we are able to enhance terahertz spectral amplitude by over 10x compared to conventional single-pass terahertz *** analysis of the depletion mechanisms reveals that 3-photon absorption and divergence of the pump beam are the primary limiters of further *** level of enhancement is promising for enabling routine spectroscopic measurements in an integrated fashion and is made more encouraging by the prospect of further enhancement by using longer pump wavelengths.

关键词： pump waveguide tuning

Load dependent microstructural evolution in an as-cast 26%Cr high chromium cast iron during unlubricated sliding

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Friction 2022年第8期10卷 1258-1275页

作者： U.Pranav NAYAK Sebastian SUÁREZ Valentin PESNEL frank MÜCKLICH María Agustina GUITAR Department of Materials Science Saarland UniversitySaarbrücken 66123Germany Materials Engineering Center Saarland Saarbrücken 66123Germany Ecole Européenne d’ingénieurs en Génie des Matériaux Universitéde LorraineNancy 54000France

In the current study,an as-cast 26%Cr high chromium cast iron(HCCI)alloy was subjected to dry-sliding linear wear tests,under different *** loads were selected based on analytically computing the critical load(PC)i.e.,the load necessary to induce plastic *** PC was calculated to be 15 N and accordingly,a sub-critical load(5 N)and an over-critical load(20 N)were *** influence of increasing the load during the wear test was investigated in terms of the matrix microstructural behaviour and its ability to support the surrounding *** morphological aspects of the wear tracks,and the deformed matrix microstructure adjacent and underneath the track was analysed by confocal laser scanning microscope(CLSM)and scanning electron microscope(SEM),*** evidence of plastic deformation of the matrix was observed below *** the contrary,at loads equal to and higher than PC,the austenitic matrix plastically deformed as evidenced by the presence of slip *** backscattered diffraction(EBSD)measurements in terms of grain reference orientation deviation,and micro-Vickers hardness of the austenitic matrix indicated a deformation depth of about 40μm at the maximum applied load of 20 *** active wear mechanisms during sliding were a combination of both adhesive and abrasive wear,although increasing the load shifted the dominant mechanism towards *** was primarily attributable to the increased propensity for carbide cracking and fracturing,combined with the inability of the hardened austenitic matrix surface and sub-surface to adequately support the broken carbide ***,the shift in the dominant wear mechanism was also reflected in the wear volume and subsequently,the wear rate.

关键词： high chromium cast iron unlubricated sliding plastic deformation wear resistance carbide spallation matrix hardness

Spatially engineered nonlinearity in resonant metasurfaces

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Photonics Research 2023年第2期11卷 252-259页

作者： ANNA FEDOTOVA MOHAMMADREZA YOUNESI MAXIMILIAN WEISSFLOG DENNIS ARSLAN THOMAS PERTSCH ISABELLE STAUDE frank SETZPFANDT Institute of Solid State Physics Friedrich Schiller University Jena07743 JenaGermany Institute of Applied Physics Abbe Center of PhotonicsFriedrich Schiller University Jena07745 JenaGermany Max Planck School of Photonics 07745 JenaGermany Fraunhofer Institute for Applied Optics and Precision Engineering 07745 JenaGermany

Spatial engineering of the nonlinear susceptibility χ^((2)) in resonant metasurfaces offers a new degree of freedom in the design of the far-field response of second-harmonic generation(SHG). We demonstrate this by applying electric field poling to lithium niobate(LN) thin films, which inverts the spontaneous polarization and thus the sign of χ^((2)). Metasurfaces fabricated in periodically poled LN films reveal the distinct influence of theχ^((2))-patterning on the spatial distribution of the second harmonic. This work is a first step toward far-field engineering of SHG in metasurfaces with electric field poling.

关键词： resonant surfaces harmonic

Effects of proteins on magnesium degradation-static *** conditions

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Journal of Magnesium and Alloys 2023年第4期11卷 1332-1342页

作者： Ruiqing Hou frank Feyerabend Heike Helmholz Vasil M.Garamus Regine Willumeit-Römer School of Materials Science and Engineering&Henan Key Laboratory of Advanced Magnesium Alloys Zhengzhou UniversityNo.100 Science AvenueZhengzhou 450001China Institute of Metallic Biomaterials Helmholtz-Zentrum Hereon(Hereon)Max-Planck-Str.1Geesthacht 21502Germany

The interaction between organic molecules and biomaterial surfaces determines the fate of biomaterials during their service life,which is also the research hotspots in the field of *** understand the mechanism of protein interaction with magnesium(Mg)degradation,alloying elements,immersion time,protein concentration and surface conditions have been previously considered for the effect of proteins on Mg ***,fluid flow,as one of the critical factors,drew little attention in this *** the present study,the effect of bovine serum albumin(BSA)and fetal bovine serum(FBS)on Mg degradation was compared under static and dynamic *** results revealed that both BSA and FBS slightly decreased the degradation rate of Mg in Hanks’balanced salt solution(HBSS)under static immersion due to the protein adsorption and the formation of a Ca/P-rich top layer on Mg surface,whereas under dynamic flow condition the degradation of Mg was significantly accelerated in the presence of BSA or *** reasons seemed to stem from the weakened protein adsorption on Mg surface in this case and the dynamically enhanced interaction between proteins and ions/products in solutions,which largely weaken the combination of the top Ca/P-rich layer with the inner corrosion product *** results highlight the importance of testing conditions for Mg characterization in vitro and the synergistic effect between different parameters on Mg degradation.

关键词： Flow Bovine serum albumin Fetal bovine serum Protein adsorption

The stability of carbon from a maize-derived hydrochar as a function of fractionation and hydrothermal carbonization temperature in a Podzol

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Biochar 2022年第1期4卷 315-326页

作者： Megan de Jager frank Schröter Michael Wark Luise Giani Institut Für Biologie Und Umweltwissenschaften Carl Von Ossietzky Univer-sitätOldenburgGermany Institut Für Chemie Carl Von Ossietzky UniversitätOldenburgGermany

Hydrochar(HC)produced by the hydrothermal carbonization(HTC)of typically wet biomass is generally considered to be less effective for carbon(C)sequestration in soils compared to biochar(BC)by pyrolysis,due to a higher content of more easily decomposable *** the recalcitrance of HC is suggested to improve with increasing HTC production temperature,the way it interacts and becomes associated with soil organic matter(SOM)fractions of different stabilities against decomposition,may also influence its effectiveness for C sequestration in *** that respect,this study aimed to verify the potential of HCs from maize silage produced at different HTC temperatures(190,210 and 230℃)for C sequestration in a HC-amended sandy loam *** do this,we conducted a pot trial experiment and traced the fate of HC-derived C(HC-C)within different SOM fractions,namely the free-and occluded particulate organic matter(POMF and POMO,respectively)fractions and that comprising organic matter(OM)bound to clays(OMCl).Approx.1 year after applying 5%of the different HTC temperature HCs to the soil,the SOM fractions were isolated by density fractionation for each HC treatment(HC190,HC210 and HC230)and the control(absent of HC).All fractions and the HCs were analyzed for organic C(OC)content and isotopic signatures(δ^(13)C).From the δ^(13)C signatures,the amount of HC-C and native soil organic carbon(SOC)within each fraction was *** C contents and decreased H/C and O/C ratios were observed with increasing HTC production temperatures,which sug-gests a lower stability for the low temperature *** ca.1 year,a loss of~20-23%of the bulk soil TOC was found in the HC-amended *** POMF fraction of the HC-amended soils showed losses of 68-81%HC-C and 52-72%native SOC,which may be due to a positive priming effect caused by HC *** POM_(O) and OM_(Cl) fractions of the HC-amended soils contained more OC than the control,indicating the integration of HC-C together wi

关键词： Hydrochar Carbon sequestration Carbon stabilization Soil organic matter fractions Soil density fractionation δ^(13)C analysis

Sensitive Information Protection Model Based on Bayesian Game

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Computers, Materials & Continua 2022年第10期73卷 883-898页

作者： Yuzhen Liu Zhe Liu Xiaoliang Wang Qing Yang Guocai Zuo frank Jiang School of Computer Science and Engineering Hunan University of Science and TechnologyXiangtan411201China Hunan Key Laboratory for Service computing and Novel Software Technology Xiangtan411201China College of computer and information engineering Hunan University of Technology and BusinessChangshaChina School of Computer Science and Information Engineering Guangzhou Maritime UniversityGuangzhouChina Hunan Software Vocational and Technical University XiangtanChina School of Engineering and IT University of New South WalesNSWAustralia

A game measurement model considering the attacker’s knowledge background is proposed based on the Bayesian game theory aiming at striking a balance between the protection of sensitive information and the quality of *** quantified the sensitive level of information according to the user’s personalized sensitive information protection *** on the probability distribution of sensitive level and attacker’s knowledge background type,the strategy combination of service provider and attacker was analyzed,and a game-based sensitive information protection model was *** the combination of strategies under Bayesian equilibrium,the information entropy was used to measure the leakage of sensitive ***,in the paper the influence of the sensitive level of information and the attacker’s knowledge background on the strategy of both sides of the game was considered *** on,the leakage of the user’s sensitive information was ***,the feasibility of the model was described by experiments.

关键词： Sensitive information game theory Bayesian equilibrium sensitive level information entropy

多中心视角下中心城市空间结构与都市圈经济绩效——以杭州都市圈为例

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中国商论 2024年第12期 1-4页

作者：程碧玥莫炎盈杨孛琦中国计量大学经济与管理学院浙江杭州310018 浙江树人学院经济与民生福祉学院浙江绍兴312030

随着世界范围内都市圈建设的不断深入,中心城市的空间格局及其对经济绩效的驱动作用,对促进城市区域可持续发展至关重要。因此,本文对2005—2020年杭州都市圈面板数据进行分析,并运用断点回归模型检验了多中心视角下中心城市空间结构对... 详细信息

随着世界范围内都市圈建设的不断深入,中心城市的空间格局及其对经济绩效的驱动作用,对促进城市区域可持续发展至关重要。因此,本文对2005—2020年杭州都市圈面板数据进行分析,并运用断点回归模型检验了多中心视角下中心城市空间结构对都市圈经济绩效的影响。研究发现:中心城市多中心空间结构对都市圈经济绩效提升总体上发挥着积极作用,其中,多功能中心发挥的作用更加明显;杭州多中心空间结构的完善与杭州都市圈经济绩效提升之间并无明显的因果联系。

关键词：区域协调发展中心城市杭州都市圈区域经济城市化建设

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Near-field launching and mapping unidirectional surface plasmon polaritons using an automated dual-tip scanning near-field optical microscope

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Photonics Research 2022年第11期10卷 2628-2641页

作者： NAJMEH ABBASIRAD ANGELA BARREDA YI-JU CHEN JER-SHING HUANG ISABELLE STAUDE frank SETZPFANDT THOMAS PERTSCH Institute of Applied Physics Abbe Center of PhotonicsFriedrich Schiller University Jena07745 JenaGermany Institute of Solid State Physics Friedrich Schiller University Jena07743 JenaGermany Research Department of Nanooptics Leibniz Institute of Photonic Technology07745 JenaGermany Fraunhofer-Institute for Applied Optics and Precision Engineering IOF 07745 JenaGermany

The spatial distribution of electromagnetic fields emitted from the aperture tip of a scanning near-field optical microscope(SNOM), which is called the emission pattern, depends on the geometry of the apex and the material composition of the tip’s coating. In previous works, experimental measurements of the emission pattern from the aperture tip were performed mostly in the far field. Moreover, the corresponding theoretical models were also developed based on these far-field measurements. Here, we have used the automated dual-tip SNOM to systematically characterize the emission from the aperture tip in the near field. In this regard, we have considered three different pairs of excitation and detection tips with distinct geometries. The emission patterns of the excitation tips were mapped using detection tips. Unidirectional surface plasmon polaritons(SPPs) at the surface of a gold platelet were launched by an excitation tip and measured in the near field by the detection tip. The experimental results were numerically reproduced by means of the Bethe–Bouwkamp model. This work puts into evidence the applicability of the automated dual-tip SNOM as the only available characterization technique to measure the emission from aperture tips in the near field. The reported asymmetric SPP radiation patterns can find applications in photonic integrated circuits or in biological and chemical sensing.

关键词： optical excitation field