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Prevalence of and risk factors for erectile dysfunction in young nondiabetic obese men:results from a regional study

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Asian Journal of Andrology 2020年第4期22卷 372-378页

作者： María Molina-Vega Maite Asenjo-Plaza María JoséBanderas-Donaire María Dolores Hernández-Ollero Silvia Rodríguez-moreno Juan Jálvarez-Millán Pablo Cabezas-sanchez Fernando Cardona-Díaz Juan Alcaide-Torres Lourdes Garrido-Sánchez Daniel Castellano-Castillo francisco J Tinahones JoséC Fernández-García Department of Endocrinology and Nutrition Virgen de la Victoria University Hospital(IBIMA)Málaga UniversityMálaga 29010Spain Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y Nutrición(CIBEROBN) Instituto de Salud Carlos IIIMadrid 28029Spain Cruz de Humilladero Primary Care Center Málaga 29010Spain Teatinos Primary Care Center Málaga 29010Spain Chemical Sanitary Consulting(CQS Lab) Madrid 28003Spain

Erectile dysfunction(ED),a condition closely related to cardiovascular morbidity and mortality,is frequently associated with *** this study,we aimed to determine the prevalence of ED and evaluate the associated risk factors in a cohort of 254 young(18–49 years)nondiabetic obese(body mass index[BMI]≥30 kg m−2)men from primary *** function(International Index of Erectile Function[IIEF-5]questionnaire),quality of life(Aging Males'Symptoms[AMS scale]),and body composition analysis(Tanita MC-180MA)were *** testosterone was determined using high-performance liquid chromatography–mass *** logistic regression analysis was used to study the factors associated with *** prevalence was 42.1%.Subjects with ED presented higher BMI,waist circumference,number of components of the metabolic syndrome,AMS score,insulin resistance,and a more unfavorable body composition than those without *** logistic regression analysis showed that a pathological AMS score(odds ratio[OR]:4.238,P40%of subjects.A pathological AMS score,the degree of obesity,and age were positively associated with ED,while elevated HDL-cholesterol levels were inversely associated with the odds of presenting *** prospective studies are needed to evaluate the long-term consequences of ED in this population.

关键词： Aging Males'Symptoms score erectile dysfunction International Index of Erectile Function-5 questionnaire obesity testosterone

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PPIs are not associated with a lower incidence of portal-hypertension-related bleeding in cirrhosis

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World Journal of Gastroenterology 2010年第46期16卷 5869-5873页

作者： Mauricio Garcia-Saenz-de-Sicilia francisco sanchez-Avila Norberto C Chavez-Tapia Gustavo Lopez-Arce Sandra Garcia-Osogobio Roberto Ruiz-Cordero Felix I Tellez-Avila Department of Gastroenterology Instituto Nacional de Ciencias Medicas y Nutrición Salvador ZubiranMexico CityMexico Medica Sur Clinic and Fundation Endoscopy Department Instituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranMexico City14000Mexico

AIM:To determine if proton pump inhibitor use in cirrhotic patients with endoscopic findings of portal hypertension is associated with a lower frequency of gastrointestinal ***:Patients with cirrhosis and endoscopic findings related to portal hypertension,receiving or not receiving proton pump inhibitor (PPI) therapy,were included *** assigned patients to two groups:group 1 patients underwent PPI therapy and group 2 patients did not undergo PPI ***:One hundred and five patients with a median age of 58 (26-87) years were included,57 (54.3%) of which were *** varices were found in 82 (78%) patients,portal hypertensive gastropathy in 72 (68.6%) patients,and gastric varices in 15 (14.3%) *** therapy was used in 45.5% of patients (n=48).Seventeen (16.1%) patients presented with upper gastrointestinal bleeding;in 14/17 (82.3%) patients,bleeding was secondary to esophageal varices,and in 3/17 patients bleeding was attributed to portal hypertensive *** related to portal hypertension according to PPI therapy occurred in 18.7% (n=9) of group 1 and in 14% (n=8) of group 2 (odds ratio:0.83,95% confidence interval:0.5-1.3,P=0.51).CONCLUSION:Portal hypertension bleeding is not associated with PPI *** findings do not support the prescription of PPIs in patients with chronic liver disease with no currently accepted indication.

关键词： Drug prescription Liver cirrhosis Portal hypertension Proton pump inhibitors Upper gastrointestinal bleeding

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Modifications of L-Glutamine and L-Leucine Transport in Proliferating Lymphocytes

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Journal of Biosciences and Medicines 2015年第3期3卷 104-109页

作者： francisco sanchez Jose Luis Gil Macarena Perán Department of Biochemistry Molecular Biology and Immunology University of Málaga Málaga Spain Department of Health Sciences University of Jaén Jaén Spain

Lymphocytes respond to mitogens that stimulate proliferation by increasing theirs metabolic activity. In this study we investigate L-Glutamine and L-Leucine uptake as markers of cell response to Concavalina A (ConcaA) stimulation, using a high-resolution flow technique. We found that lymphocytes induced to blast transformation enhanced rate and efficiency of amino acid uptake during cell proliferation. Considering that increases in transport is the first quantifiable response of cells during malignant transformation, amino acid uptake could also be useful as an early marker of malignancy.

关键词： Cell Membrane Transport Lymphocytes L-Glutamine L-Leucine Malignancy Biomarkers

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A Real-World Perspective on Interfacility Transfers of Acute Ischemic Stroke from a Semi-Rural Center

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Open Journal of Emergency Medicine 2020年第1期8卷 1-12页

作者： Lluís Llauger Ester Puyuelo francisco sanchez-Mendez Emergency Department Vic University Hospital Vic Spain

Introduction: Interfacility transfers (IFT) of acute ischemic stroke (AIS) may not always lead to a better prognosis. Methods: Retrospective cohort study included AIS patients at an emergency department (ED) with telestroke. Multiple linear regression for departure time from ED (DT), quantile regression for length of in-hospital stay (LOS), and Kaplan-Meier estimator with Cox proportional hazards model for one-year survival (SV) were performed. Results: 192 patients included were categorised according to IFT. Mechanical thrombectomy was performed in 50% who had been transferred. Differences were found in DT, discharge disposition and LOS. An inverse relationship existed between DT and NIHSS. The strongest predictor of LOS was TACS (β = 3.14 [0.03 - 8.49];p = 0.005). SV was related to IFT (HR 4.68 [1.37 - 16.07];p = 0.014), age (HR 1.1 [1.04 - 1.17]), BI Conclusions: Shared decision-making with a stroke unit through telemedicine enabled a standardised clinical management in a non-metropolitan setting. Several improvement opportunities were identified: multimodal computed tomography availability before transfer, as well as optimization of response time and training in neurosonology of emergency physicians.

关键词： Stroke Emergency Room Transportation of Patients Prognosis

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Assessment of the Connection of Antisocial-Criminal Behavior, Corruption and Depression in College Students

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Psychology Research 2017年第3期7卷 131-139页

作者： Iris Xochitl Galicia Moyeda Alejandra sanchez Velasco francisco Javier Robles Ojeda Universidad Nacional Autonoma de Mexico Iztacala Mexico

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Clinical characteristics and surgical treatment of schwannomas of the esophagus and stomach: A case series and systematic review

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World Journal of Gastrointestinal Oncology 2019年第9期11卷 750-760页

作者： Jesús Morales-Maza francisco Ulises Pastor-Sifuentes Germán E Sánchez-Morales Emilio sanchez-Garcia Ramos Oscar Santes Uriel Clemente-Gutiérrez Adriana Simoneta Pimienta-Ibarra Heriberto Medina-Franco Department of Surgery Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

BACKGROUND Gastrointestinal schwannomas are slow-growing benign mesenchymal neoplasms that originate from Schwann cells of the nerve sheath of Auerbach′s plexus or less frequently from Meissner′s *** main differential diagnosis of gastric schwannomas are the gastrointestinal stromal tumors(GISTs),which are classified by their *** treatment of choice for gastric schwannomas is surgery where laparoscopy plays an important *** resection,subtotal or total gastrectomy can be *** its counterpart,esophageal schwannomas are benign tumors of the esophagus that are very uncommon since they comprise less than 2%of all esophageal *** main differential diagnosis is the leiomyoma which corresponds to the most common benign esophageal tumor,followed by *** treatment consists on tumoral enucleation or *** To review the available literature about gastrointestinal schwannomas;especially lesions from de stomach and esophagus,including diagnosis,treatment,and follow up,as well as,reporting our institutional *** A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes *** following databases were used for reviewing process:Pub Med,Ovid,MEDLINE,and *** English language manuscripts were *** gastrointestinal schwannomas specifically located in the esophagus and stomach were *** that did not report long-term follow-up were *** Gastric localization showed a higher prevalence in both,the literature review and our institution:94.95%(n=317)and 83%(n=5)*** a follow-up with disease-free survival greater than 36 mo in most cases:62.01%(n=80)vs66.66%(n=4).In both groups,the median size was>4.1 *** treatment is curative in most cases CONCLUSION Schwannoma must be taken into account in the differential diagnosis of gastrointestinal mesenchymal *** has a good prognosis,and most are benig

关键词： Schwannoma Esophagus Stomach Surgery Systematic review

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Complications of extrahepatic echinococcosis:Fistulization of an adrenal hydatid cyst into the intestine

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World Journal of Gastroenterology 2008年第9期14卷 1467-1469页

作者： Juan francisco Ruiz-Rabelo Manuel Gomez-Alvarez Joaquin sanchez-Rodriguez Sebastian Rufian Pea Department of General Surgery Reina Sofia University Hospital Avda Menendez Pidal S/N Cordoba 14004 Spain

Echinococcal cysts are usually found in liver and lungs, but any other organ can potentially be involved. Extrahepatic disease due to hydatid cyst may develop in the abdominal and pelvic cavity, aside from in other less common locations, which may make both diagnosis and treatment more complex. We present a rare case of extrahepatic echinococcosis in a 70-year old patient with a 4-d history of dull abdominal pain, anemia within the transfusion range and fever. She underwent surgery for left renal hydatid cysts 30 years ago. After non operative treatment, imaging studies showed a calcified hydatid cyst in a retrogastric location communicating with a proximal jejunal loop. En-block resection of the mass together with the adrenal gland was performed including closure of the enteric fistula. Anatomic pathology confirmed the diagnosis of a calcified hydatid cyst of left adrenal origin. Surgery is the treatment of choice and most authors recommend removal of cyst and adrenal gland.

关键词：包虫病并发症肾上腺囊肿外科手术

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正癸烷+正戊醇,+1-己醇,+庚醇二元混合物在293.15到363.15K和大气压力下的密度和粘度（英文）

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Chinese Journal of Chemical Engineering 2015年第3期23卷 559-571页

作者： Alejandro Estrada-Baltazar Micael Gerardo Bravo-sanchez Gustavo Arturo Iglesias-Silva Juan francisco Javier Alvarado Edgar Omar Castrejon-Gonzalez Mariana Ramos-Estrada Department of Chemical Engineering Instituto Tecnologico de Celaya Faculty of Chemical Engineering Universidad Michoacana de San Nicolas de Hidalgo

Densities(ρ) and dynamic viscosities(η) for three binary mixtures of n-decane with 1-pentanol,1-hexanol and1-heptanol are presented at temperatures from 293.15 to 363.15 K and atmospheric pressure over the entire composition *** density and viscosity are measured using a vibrating tube densimeter and a cylindrical Couette type rotating viscometer,*** molar volumes(V^E),viscosity deviations(△η) and excess Gibbs energy of activation of viscous flow(△G^(*E)) are calculated from the experimental *** and structural interactions are indicated by the sign and magnitude of these *** molar volumes and infinity dilution molar partial volumes are also calculated for each binary *** results are correlated using Redlich-Kister type equations.

关键词：振动管密度计二元混合物动态粘度大气压力正戊醇正癸烷温度庚醇

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Blood Flow-Restricted Training in Older Adults:A Narrative Review

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Journal of Science in Sport and Exercise 2020年第1期2卷 25-37页

作者： Abel Plaza-Florido Jairo H.Migueles Antonio Piepoli Pablo Molina-Garcia Maria Rodriguez-Ayllon Cristina Cadenas-sanchez Jose Mora-Gonzalez Irene Esteban-Cornejo francisco B.Ortega PROFITH"PROmoting FITness and Health Through Physical Activity"Research Group Sport and Health University Research Institute(iMUDS)Department of Physical and Sports EducationFaculty of Sport SciencesUniversity of GranadaCarretera de Alfacars/nCP 18071 GranadaSpain Department of Health Sciences Faculty of Health SciencesUniversity of JaénResearch Group CTS-026:Study Group on Physical ActivityPhysiotherapy and HealthJaénSpain Department of Rehabilitation Sciences KU Leuven-University of LeuvenLeuvenBelgium Department of Psychology Center for Cognitive and Brain HealthNortheastern UniversityBostonMAUSA

Background Low-intensity resistance training(LI-RT)combined with blood flow restriction(BFR)is an alternative to traditional moderate-high-intensity resistance training to increase strength and muscle ***,the evidence about the efficacy of this novel training method to increase strength and muscle mass in healthy and older adults with patholo-gies is ***,the possible risk and adverse effects with BFR training methodology in older adults should be ***(1)To summarize the current evidence on training with BFR strategies in older adults aiming to improve strength and to increase muscle mass;and(2)to provide recommendations for resistance and aerobic training with BFR in older adults based on the studies *** Studies that investigated the chronic responses to resistance training or aerobic training with BFR related to strength and muscle mass changes in older adults were *** independent researchers conducted the search in PubMed,Web of Science,and Google Scholar databases from their inception up to November 1,*** Seventeen out of 35 studies,which performed resistance or aerobic training with BFR in older adults focused on strength and muscle mass outcomes,were included in this *** performing resistance and aerobic train-ing with BFR found better improvements in strength and higher increase in muscle mass compared to non-BFR groups that performed the same training ***-intensity resistance training(HI-RT)without BFR provided greater improvements in strength and a similar increase in muscle mass compared to light-intensity resistance training(LI-RT)with *** Current evidence suggests that LI-RT and/or aerobic training with BFR improves strength and increases muscle mass in older ***-intensity training without BFR would normally not obtain such ***,LI-RT and aerobic training with BFR is an alternative to traditional methods to improve strength an

关键词： Hyertroply Strength Vascular oclusion Reistance raining Elderly aduts

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Modeling and simulation of normal and hemiparetic gait

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Frontiers of Mechanical Engineering 2015年第3期10卷 233-241页

作者： Lely A. LUENGAS Esperanza CAMARGO Giovanni sanchez Technological Faculty Universidad Distrital Francisco Jose de CaldasBogota Colombia Engineering Faculty Universidad de San Buenaventura BogotaColombia

Gait is the collective term for the two types of bipedal locomotion, walking and running. This paper is focused on walking. The analysis of human gait is of interest to many different disciplines, including biomecha- nics, human-movement science, rehabilitation and medicine in general. Here we present a new model that is capable of reproducing the properties of walking, normal and pathological. The aim of this paper is to establish the biomechanical principles that underlie human walking by using Lagrange method. The constraint forces of Rayleigh dissipation function, through which to consider the effect on the tissues in the gait, are included. Depending on the value of the factor present in the Rayleigh dissipation function, both normal and pathological gait can be simulated. First of all, we apply it in the normal gait and then in the permanent hemiparetic gait. Anthropometric data of adult person are used by simulation, and it is possible to use anthropometric data for children but is necessary to consider existing table ofanthropometric data. Validation of these models includes simulations of passive dynamic gait that walk on level ground. The dynamic walking approach provides a new perspective of gait analysis, focusing on the kinematics and kinetics of gait. There have been studies and simulations to show normal human gait, but few of them have focused on abnormal, especially hemiparetie gait. Quantitative comparisons of the model predictions with gait measurements show that the model can reproduce the significant characteristics of normal gait.

关键词： bipedal gait biomechanics dynamic walking,gait model human gait hemiparetic human gait

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